# FATION NOSCA9 TROUBLE SERUM for mature skin

**Lovi Fit: Average fit for mature skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/fr/p/fation/nosca9-trouble-serum/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for France.

Brand: [FATION](https://lovi.care/skincare/fr/brands/fation)
Category: [Serums and treatments](https://lovi.care/skincare/fr/best/serums)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for mature skin; other serums fit it better.

## Why this fit

- This product offers moderate benefits for your normal skin, with ingredients like Hyaluronic Acid and Glycerin providing essential hydration and Ceramide NP supporting your skin barrier. While it addresses general skincare needs, it does not specifically target your wrinkles and fine lines.
- Artemisia Princeps Leaf Extract and Centella Asiatica Extract are included for their calming and blemish-reducing properties, which are beneficial for acne-prone skin but less relevant to your primary concerns.
- The formula is safe for your normal skin, as it lacks harsh ingredients and poses no irritation risks.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/fr/p/fation/nosca9-trouble-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/fr/p/fation/nosca9-trouble-serum/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/fr/p/fation/nosca9-trouble-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/fr/p/fation/nosca9-trouble-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/fr/p/fation/nosca9-trouble-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/fr/p/fation/nosca9-trouble-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/fr/p/fation/nosca9-trouble-serum/for/mature-skin): Average (this page)
- [Dry sensitive skin](https://lovi.care/skincare/fr/p/fation/nosca9-trouble-serum/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/fr/p/fation/nosca9-trouble-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Artemisia Princeps Leaf Extract, Glycerin, Panthenol

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- A lipid mixture enriched by ceramide NP with fatty acids of diverse chain lengths significantly improved skin barrier recovery rate, stratum corneum integrity, and hydration compared to a vehicle cream in healthy adult male volunteers with corticosteroid-impaired skin. ([Skin Pharmacology and Physiology, 2022](https://pubmed.ncbi.nlm.nih.gov/34348350/))
- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Artemisia princeps-derived nanovesicles accelerate cell proliferation, decrease senescence-associated beta-galactosidase activity, inhibit MMP-1 activity more effectively than EGCG, and increase procollagen type I expression in human dermal cells and skin models. ([Journal of Extracellular Biology, 2025](https://pubmed.ncbi.nlm.nih.gov/40292385/))
- Artemisia annua aqueous extract increased the itching threshold, inhibited TSLP expression, and promoted FLG mRNA expression in in vitro and in vivo models. ([Journal of Ethnopharmacology, 2024](https://pubmed.ncbi.nlm.nih.gov/37604330/))
- Artemisia Capillaris Thunb. extract protects human HaCaT keratinocytes from UVB-induced apoptosis and inflammation by suppressing the cGAS/STING signaling pathway. ([Journal of Photochemistry and Photobiology. B, Biology, 2024](https://pubmed.ncbi.nlm.nih.gov/39032373/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans. ([Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/))

## Why other serums fit mature skin better

- Caviar oil enhanced adipocyte differentiation in vitro, reduced MMP expression while increasing collagen and elastin formation ex vivo, and improved skin moisture, elasticity, and density in 102 participants over four weeks of Cavi Balm usage compared to baseline. ([In Vivo, 2023](https://pubmed.ncbi.nlm.nih.gov/37652485/))
- Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants. ([Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/))
- A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/))

## What reviewers say

Based on a very large amount of data, this serum is widely praised by users with acne-prone and sensitive skin for its ability to rapidly calm redness and inflammation without clogging pores. While it is not an overnight miracle cure for active breakouts, consistent use strengthens the skin barrier and significantly reduces the severity and duration of hormonal acne and irritation.

- Liked: Lightweight & fast absorbing (mostly mentioned)
- Liked: Rapidly calms redness (mostly mentioned)
- Liked: Improves barrier health (often mentioned)
- Liked: Non-comedogenic (often mentioned)
- Disliked: Not moisturizing enough (sometimes noted)
- Disliked: Price point (sometimes noted)
- Disliked: Slight stickiness (rarely noted)
- Disliked: Slow results on acne (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
- Apply this serum after your toner and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- You can apply the serum on dry skin for the best results against fine lines.
- Always do a patch test before your first use and avoid the sensitive eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Fation Nosca9 Serum work for mature skin?

This serum works moderately well for mature skin because ingredients like hyaluronic acid, glycerin, and ceramide NP keep your skin hydrated and help support the skin barrier. While it is safe and calming, it lacks ingredients that target wrinkles and fine lines. Treatments that fit mature skin better need potent antioxidants, anti-aging components, and ingredients that improve skin elasticity and firmness.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Skin Pharmacology and Physiology, 2022](https://pubmed.ncbi.nlm.nih.gov/34348350/)

### Which ingredients make this serum a good fit for mature skin?

Glycerin, Hyaluronic Acid, and Ceramide NP make this serum a good fit by providing essential hydration and supporting the skin barrier. However, mature skin needs a product of this type that also targets wrinkles and fine lines with ingredients that improve skin elasticity.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Skin Pharmacology and Physiology, 2022](https://pubmed.ncbi.nlm.nih.gov/34348350/)

### What does Mugwort Leaf Extract do for mature skin?

Mugwort Leaf Extract helps mature skin by supporting its natural barrier proteins, which keeps the skin feeling soft and smooth. This ingredient helps strengthen the outer layer so it holds onto moisture better as you age.
Sources: [International Journal of Molecular Sciences, 2017](https://pubmed.ncbi.nlm.nih.gov/28892018/)

### What does Glycerin do for mature skin?

Glycerin helps keep mature skin feeling soft and smooth by drawing moisture into the outer layer and locking it in. This daily hydration boost supports the skin barrier, keeping dry areas comfortable and protected against irritation.
Sources: [The British Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18510666/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Where does this serum go in a skincare routine for mature skin?

This treatment goes in the evening routine after cleansing and before moisturizing. To better fit mature skin, a product of this type needs firming peptides and antioxidants that specifically target wrinkles and fine lines.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first and following it with your retinol product. This helps keep your skin hydrated and is unlikely to cause irritation since the formula is gentle.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Skin Pharmacology and Physiology, 2022](https://pubmed.ncbi.nlm.nih.gov/34348350/)

### How often should I use this serum?

You can use this treatment in the evening as part of your routine. Mature skin needs products with firming ingredients like retinoids and peptides to target fine lines and wrinkles.

### Can this serum clog pores, cause breakouts or purging for mature skin?

This serum is unlikely to clog pores or cause breakouts on mature skin, as it lacks harsh ingredients and poses no irritation risks. To properly care for mature skin, a product of this type needs ingredients that target wrinkles and fine lines while supporting firmness and elasticity.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for mature skin

- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/fr/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/mature-skin) — Superior fit — €57.00 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/fr/p/skinceuticals/c-e-ferulic/for/mature-skin) — Superior fit — €139.99 at Amazon
- [La Prairie Skin Caviar Liquid Lift](https://lovi.care/skincare/fr/p/la-prairie/skin-caviar-liquid-lift/for/mature-skin) — High fit — €599.90 at Amazon

## Pairs well with

- Cleanser: [La Roche-Posay Hydrating Gentle Cleanser](https://lovi.care/skincare/fr/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/mature-skin) — Superior fit — €28.02 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/fr/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — €18.45 at Amazon
- Moisturizer: [Elizabeth Arden Ceramide Lift and Firm Night Cream](https://lovi.care/skincare/fr/p/elizabeth-arden/advanced-ceramide-lift-and-firm-night-cream/for/mature-skin) — Superior fit — €76.29 at Amazon

## Where to buy

No store in France has a checked price for this product, so the page shows none.

## Ingredients

Artemisia Princeps Leaf Extract, Water, Glycerin, Dipropylene Glycol, Panthenol, 1,2-Hexanediol, Pentylene Glycol, Hyaluronic Acid, Diethoxyethyl Succinate, Hydroxyethyl Urea, Acrylates C10-30 Alkyl Acrylate Cross Polymer, Ammonium Acryloyldimethyltaurate Vp Copolymer, Tromethamine, Allantoin, Centella Asiatica Extract, Hydroxyacetophenone, Ethylhexylglycerin, Polyglyceryl-10 Laurate, Succinic Acid, Xanthan Gum, Sodium Heparin, Pyrus Malus Fruit Extract, Tocopherol, Caprylyl Capryl Glucoside, Hydrogenated Lecithin, Ceramide Np
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/fation/nosca9-trouble-serum/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/fation/nosca9-trouble-serum/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/fation/nosca9-trouble-serum/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/fation/nosca9-trouble-serum/for/mature-skin
- France: https://lovi.care/skincare/fr/p/fation/nosca9-trouble-serum/for/mature-skin (this page)
- Italy: https://lovi.care/skincare/it/p/fation/nosca9-trouble-serum/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/fation/nosca9-trouble-serum/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/fation/nosca9-trouble-serum/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/fation/nosca9-trouble-serum/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/fation/nosca9-trouble-serum/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/fation/nosca9-trouble-serum/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/fation/nosca9-trouble-serum/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/fation/nosca9-trouble-serum/for/mature-skin