# COSRX The 6 Peptide Skin Booster Serum for acne-prone skin

**Lovi Fit: High fit for acne-prone skin.**
Combination Skin Fit: High · Effectiveness: Superior · Safety: Excellent.

Page: https://lovi.care/skincare/fr/p/cosrx/the-6-peptide-skin-booster-serum/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for France.

Brand: [COSRX](https://lovi.care/skincare/fr/brands/cosrx)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/fr/best/moisturizers)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for acne-prone skin; a few moisturizers fit it even better.

## Why this fit

- Excellent for your combination skin and acne concerns, as niacinamide helps regulate oil production and reduce inflammation, while acetyl hexapeptide-8 supports skin health and combats breakouts. Polyquaternium-51 provides essential hydration, balancing both oily and dry areas effectively.
- The high concentrations of peptides like copper tripeptide-1 and acetyl hexapeptide-8 offer significant moisturizing and anti-aging benefits, visibly reducing fine lines and wrinkles.
- The formula is safe for your skin, containing soothing ingredients like tocopherol and allantoin and lacking any harsh or irritating components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/fr/p/cosrx/the-6-peptide-skin-booster-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/fr/p/cosrx/the-6-peptide-skin-booster-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/fr/p/cosrx/the-6-peptide-skin-booster-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/fr/p/cosrx/the-6-peptide-skin-booster-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/fr/p/cosrx/the-6-peptide-skin-booster-serum/for/acne-prone-skin): High (this page)
- [Skin with dark spots](https://lovi.care/skincare/fr/p/cosrx/the-6-peptide-skin-booster-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/fr/p/cosrx/the-6-peptide-skin-booster-serum/for/mature-skin): Superior
- [Dry sensitive skin](https://lovi.care/skincare/fr/p/cosrx/the-6-peptide-skin-booster-serum/for/dry-sensitive-skin): Superior
- [Oily acne-prone skin](https://lovi.care/skincare/fr/p/cosrx/the-6-peptide-skin-booster-serum/for/oily-acne-prone-skin): High

## Key ingredients

Sodium Hyaluronate, Peptides, N-Acetyl Glucosamine, Niacinamide, Allantoin

## What the research says

- Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group. ([American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/))
- Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days. ([Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/))
- Acetyl hexapeptide-3 and tripeptide-10 citrulline demonstrated antiwrinkle efficacy and decreased transepidermal water loss in twenty-four healthy volunteers compared to control groups, though synergistic effects between the two peptides remained unclear. ([Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28150423/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical 2% N-acetyl glucosamine reduced facial hyperpigmentation in an 8-week split-face clinical test, with an even greater effect observed when combined with 4% niacinamide. ([Journal of Cosmetic Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17348991/))
- N-acetyl-glucosamine-loaded nanostructured lipid carriers successfully delivered the hydrophilic agent through the skin and reduced melanin distribution in healthy volunteers. ([Advanced Pharmaceutical Bulletin, 2016](https://pubmed.ncbi.nlm.nih.gov/28101465/))
- Topical cosmetic products containing hyaluronic acid, N-acetyl glucosamine, and gamma-amino butyric acid improved skin hydration by 24.28% to 33.60%, elasticity by 11.98%, and skin lightening by 5.26% over 2 months in 20 female participants. ([Journal of Cosmetic and Laser Therapy, 2019](https://pubmed.ncbi.nlm.nih.gov/30040516/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment. ([Aesthetic Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29948103/))

## What reviewers say

Based on a very large amount of data, users consistently praise this serum as a lightweight, water-like "booster" that significantly improves skin texture and hydration without heaviness. It is widely celebrated for smoothing pores and creating a "glass skin" glow. A small minority of users with specific sensitivities experienced breakouts or closed comedones.

- Liked: Lightweight & fast-absorbing (mostly mentioned)
- Liked: Hydrating & plumping (often mentioned)
- Liked: Improves skin texture (often mentioned)
- Liked: Gentle & non-irritating (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Ingredient sensitivities (rarely noted)
- Disliked: No visible results (rarely noted)
- Disliked: Sticky residue (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help keep breakouts under control.
- Apply after your cleanser and toner, and make sure to use your SPF right after in the morning.
- Gently spread a small amount of moisturizer over your face using soft motions. Let it absorb into the skin for a minute before getting dressed or applying makeup.
- Apply on slightly damp skin to help lock in extra moisture. This keeps your combination skin balanced without feeling heavy.
- Avoid the eye area and do a patch test before your first use. Stop using if you feel any irritation.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes COSRX The 6 Peptide Skin Booster Serum a great fit for acne-prone skin?

COSRX The 6 Peptide Skin Booster Serum is a great fit for acne-prone skin because niacinamide helps regulate oil production and reduce inflammation, while peptides like acetyl hexapeptide-8 support skin health and combat breakouts. The formula also provides essential hydration to balance oily and dry areas effectively without any harsh components.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/)

### Which ingredients make this serum a good fit for acne-prone skin?

Niacinamide helps regulate oil production and reduce inflammation, while acetyl hexapeptide-8 supports skin health and combats breakouts. Additionally, soothing components like allantoin and tocopherol help keep acne-prone skin calm and comfortable.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/)

### What does Hyaluronic Acid do for acne-prone skin?

Hyaluronic acid helps acne-prone skin by soothing irritation, calming redness, and keeping the skin balanced without clogging pores. When combined with targeted ingredients like zinc oxide, it may also help reduce breakouts.
Sources: [Biomedicines, 2025](https://pubmed.ncbi.nlm.nih.gov/41007718/), [Drug Delivery, 2017](https://pubmed.ncbi.nlm.nih.gov/28155509/)

### What do Peptides do for acne-prone skin?

Peptides help calm acne-prone skin by reducing redness and soothing inflammation while supporting the skin barrier. Certain advanced peptide formulas also work to target acne-causing bacteria and help balance oil production.
Sources: [Biochemical Pharmacology, 2025](https://pubmed.ncbi.nlm.nih.gov/39662606/), [Bioresources and Bioprocessing, 2026](https://pubmed.ncbi.nlm.nih.gov/42219443/)

### Where does this serum go in a skincare routine for acne-prone skin?

This serum goes in the evening routine as a treatment step, applied after cleansing and before moisturizing. Putting treatments in the evening helps keep things simple and provides extra safety around sun exposure.

### Can I use it with retinol, and in what order?

Yes, you can use this moisturizing treatment with retinol by applying the treatment first to keep your skin calm and hydrated, followed by your retinol. This layered approach helps reduce the irritation and dryness that retinol can sometimes cause on acne-prone skin.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use this serum?

You can use this serum daily as part of your evening routine. Daily application helps keep acne-prone skin balanced and hydrated while improving overall texture and reducing breakouts.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can it clog pores, cause breakouts or purging for acne-prone skin?

This serum is a great fit for acne-prone skin because niacinamide helps balance oil and soothe redness, while soothing ingredients like allantoin keep the formula gentle and unlikely to cause irritation. Reviewers rarely mention breakouts, and the gentle ingredients mean it is unlikely to clog pores.

### Can I use this serum around the eyes or on my body?

You can safely use this moisturizing treatment on the thin skin around your eyes and on your body to help smooth fine lines and keep areas soft and hydrated. It is unlikely to cause irritation because the formula includes soothing ingredients and lacks harsh components.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [Polymers, 2023](https://pubmed.ncbi.nlm.nih.gov/37896378/)

### Is it fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for acne-prone skin

- [Revision Skincare Hydrating Serum](https://lovi.care/skincare/fr/p/revision-skincare/hydrating-serum/for/acne-prone-skin) — Superior fit — €191.05 at Amazon
- [innisfree Green Tea Seed Hyaluronic Acid Hydrating Serum](https://lovi.care/skincare/fr/p/innisfree/green-tea-seed-hyaluronic-acid-hydrating-serum/for/acne-prone-skin) — High fit — €29.00 at Amazon
- [Isntree Green Tea Fresh Serum](https://lovi.care/skincare/fr/p/isntree/green-tea-fresh-serum/for/acne-prone-skin) — High fit — €12.56 at Amazon

## Pairs well with

- Cleanser: [B.LAB Matcha Hydrating Foam Cleanser](https://lovi.care/skincare/fr/p/b-lab/matcha-hydrating-foam-cleanser/for/acne-prone-skin) — Superior fit — €13.98 at Amazon
- Hydrating Toner: [La Mer The Tonic](https://lovi.care/skincare/fr/p/la-mer/the-tonic/for/acne-prone-skin) — Superior fit — €10.25 at Amazon
- SPF: [d'Alba Piedmont Waterfull Mild Sunscreen](https://lovi.care/skincare/fr/p/d-alba/piedmont-waterfull-mild-sunscreen/for/acne-prone-skin) — Superior fit — €16.99 at Amazon

## Where to buy

- Amazon.fr: €18.60 (https://www.amazon.fr/dp/B0CCJ3SRB9?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1)
- Lookfantastic: €23.29 (https://www.lookfantastic.fr/p/cosrx-the-6-peptide-skin-booster-serum-150ml/15212379/)
- Notino: €23.90 (https://www.notino.fr/cosrx/the-6-peptide-skin-booster-serum-serum-regenerant-et-raffermissant-pour-peaux-seches-a-sensibles/p-16246267/)
Prices checked 10 Oct – 6 Nov 2026.

## Ingredients

Water, Dipropylene Glycol, Glycerin, Pentylene Glycol, 1,2-Hexanediol, Niacinamide, Ammonium Acryloyldimethyltaurate Vp Copolymer, Polyacrylate Crosspolymer-6, Butylene Glycol, Xanthan Gum, Ethylhexylglycerin, Adenosine, Polyquaternium-51, Disodium Edta, Citric Acid, Caprylyl Glycol, Betaine, T-Butyl Alcohol, Sodium Pca, Sodium Lactate, Acetyl Hexapeptide-8, Copper Tripeptide-1, Pca, Sh-Polypeptide-121, Serine, Alanine, Allantoin, Sodium Hyaluronate, Acetyl Glucosamine, Glycine, Glutamic Acid, Lysine Hcl, Threonine, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Arginine, Tocopherol, Oligopeptide-68, Proline, Dextran, Palmitoyl Tripeptide-8, Glycine Soja Oil Soybean Oil, Hydrogenated Lecithin, Potassium Sorbate, Sodium Oleate
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/cosrx/the-6-peptide-skin-booster-serum/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/cosrx/the-6-peptide-skin-booster-serum/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/cosrx/the-6-peptide-skin-booster-serum/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/cosrx/the-6-peptide-skin-booster-serum/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/cosrx/the-6-peptide-skin-booster-serum/for/acne-prone-skin (this page)
- Italy: https://lovi.care/skincare/it/p/cosrx/the-6-peptide-skin-booster-serum/for/acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/cosrx/the-6-peptide-skin-booster-serum/for/acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/cosrx/the-6-peptide-skin-booster-serum/for/acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/cosrx/the-6-peptide-skin-booster-serum/for/acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/cosrx/the-6-peptide-skin-booster-serum/for/acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/cosrx/the-6-peptide-skin-booster-serum/for/acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/cosrx/the-6-peptide-skin-booster-serum/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/cosrx/the-6-peptide-skin-booster-serum/for/acne-prone-skin