# CELL BY CELL Soft Enzyme Powder for acne-prone skin

**Lovi Fit: Average fit for acne-prone skin.**
Combination Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/fr/p/cell-by-cell/soft-enzyme-powder/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for France.

Brand: CELL BY CELL
Category: [Exfoliants](https://lovi.care/skincare/fr/best/exfoliators)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for acne-prone skin; other products fit it better.

## Why this fit

- Offers moderate cleansing for your combination skin, as Sodium Cocoyl Isethionate and Sodium Lauroyl Glutamate help remove impurities without causing irritation. Zea Mays Starch and Aloe Barbadensis Leaf Juice further support oil absorption and hydration, making it generally suitable for your skin type.
- While beneficial for general cleansing, the formula does not directly target your primary concerns of acne, blemishes, and breakouts.
- The product is safe for your acne-prone skin, containing no harsh or prohibited ingredients that would cause irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/fr/p/cell-by-cell/soft-enzyme-powder/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/fr/p/cell-by-cell/soft-enzyme-powder/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/fr/p/cell-by-cell/soft-enzyme-powder/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/fr/p/cell-by-cell/soft-enzyme-powder/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/fr/p/cell-by-cell/soft-enzyme-powder/for/acne-prone-skin): Average (this page)
- [Skin with dark spots](https://lovi.care/skincare/fr/p/cell-by-cell/soft-enzyme-powder/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/fr/p/cell-by-cell/soft-enzyme-powder/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/fr/p/cell-by-cell/soft-enzyme-powder/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/fr/p/cell-by-cell/soft-enzyme-powder/for/oily-acne-prone-skin): Average

## Key ingredients

Sodium Cocoyl Isethionate, Aloe Barbadensis Leaf Juice, Collagen, Allantoin, Opuntia Ficus-Indica Stem Extract

## What the research says

- Sodium cocoyl isethionate micelles are too large to penetrate stratum corneum aqueous pores, resulting in significant steric hindrance that prevents skin barrier perturbation and explains its skin mildness. ([Journal of Cosmetic Science, 2007](https://pubmed.ncbi.nlm.nih.gov/17598025/))
- A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo. ([Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/))
- Topical aloe vera gel significantly accelerated split-thickness skin graft donor-site healing compared to placebo in 12 patients, but showed no significant difference in pain relief. ([Plastic and Reconstructive Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29649056/))
- Topical application of Aloe vera cream reduced postoperative pain at rest and during defecation, accelerated wound healing at two weeks, and decreased analgesic requirements in patients after open hemorrhoidectomy compared to placebo. ([Journal of Alternative and Complementary Medicine, 2010](https://pubmed.ncbi.nlm.nih.gov/20569031/))
- Formulations containing 0.10%, 0.25%, and 0.50% freeze-dried Aloe vera extract increased stratum corneum water content compared with the vehicle in 20 female subjects, while transepidermal water loss was not modified. ([Skin Research and Technology, 2006](https://pubmed.ncbi.nlm.nih.gov/17026654/))
- Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35818134/))
- Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks. ([International Journal of Molecular Sciences, 2022](https://pubmed.ncbi.nlm.nih.gov/35163025/))
- Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers. ([Marine Drugs, 2023](https://pubmed.ncbi.nlm.nih.gov/36827098/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment. ([Aesthetic Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29948103/))
- Opuntia ficus-indica extract and its isorhamnetin-glucosyl-rhamnoside suppressed nitric oxide, COX-2, TNF-alpha, and IL-6 production in vitro and inhibited croton oil-induced ear edema in vivo. ([BioMed Research International, 2015](https://pubmed.ncbi.nlm.nih.gov/25821823/))
- Opuntia ficus-indica extract activated AHR-NRF2 signaling, inhibited reactive oxygen species generation, and upregulated filaggrin and loricrin expression in human keratinocytes. ([Journal of Medicinal Food, 2015](https://pubmed.ncbi.nlm.nih.gov/26061570/))
- Pre-treating normal human keratinocytes with an Opuntia ficus-indica cladode water extract protected against UVA-induced oxidative stress and apoptosis by inhibiting free radicals, lipid peroxidation, and GSH depletion. ([Bioorganic & Medicinal Chemistry Letters, 2017](https://pubmed.ncbi.nlm.nih.gov/29107540/))

## Why other products fit acne-prone skin better

- A fixed combination of hydroxypinacolone retinoate, retinol glycospheres, and papain glycospheres in aqueous gel applied once daily for 12 weeks achieved a 41% mean reduction in GAGS score and a 40.8% mean reduction in total lesions, with 15.3% of patients experiencing mild to moderate local side effects, in 94 evaluable patients with comedonal-papular, mild to moderate acne of the face. ([Giornale Italiano Di Dermatologia E Venereologia, 2015](https://pubmed.ncbi.nlm.nih.gov/25876142/))

## What reviewers say

Based on limited data, users consistently describe this cleanser as an exceptionally gentle powder-to-foam exfoliant that effectively smooths skin texture without stripping moisture. It is frequently recommended for sensitive, acne-prone, and oily skin types, with many users reporting a reduction in small bumps and a baby-soft finish after use.

- Liked: Gentle exfoliation (mostly mentioned)
- Liked: Skin texture improvement (often mentioned)
- Liked: Deep cleansing (sometimes noted)
- Liked: Non-stripping (sometimes noted)
- Disliked: Packaging design (sometimes noted)
- Disliked: Clumping issues (rarely noted)
- Disliked: Messy application (rarely noted)
- Disliked: Price vs. quantity (rarely noted)

## How to apply

- Use your enzyme powder cleanser as part of your PM weekly routine. Start by using it once a week and build up slowly if your skin is happy.
- Place this step after your regular cleanser and before applying your hydrating toner. Follow the weekly routine order for the best results.
- Mix the powder with a little water in your hands to create a soft foam. Gently massage onto your face and avoid rubbing too hard.
- Apply the enzyme powder cleanser on slightly damp skin to help activate the formula evenly. Make sure your face is clean before applying.
- Avoid the sensitive eye area during application. Do a patch test first and do not combine this with strong acids on the same night.
- Video: https://storage.pora.ai/2d8db6e67371d665a6a7736b5ed5d762.mp4

## Questions and answers

### How well does CELL BY CELL Soft Enzyme Powder work for acne-prone skin?

CELL BY CELL Soft Enzyme Powder works moderately well for acne-prone skin by gently removing impurities without irritation, though it does not directly target breakouts. An enzyme powder cleanser for this skin needs ingredients like Niacinamide or Licorice Root Extract to actively target blemishes alongside safe, soothing, and hydrating care.
Sources: [Journal of Cosmetic Science, 2007](https://pubmed.ncbi.nlm.nih.gov/17598025/)

### Which ingredients make this cleanser a good fit for acne-prone skin?

Aloe Barbadensis Leaf Juice and Sodium Cocoyl Isethionate help make this cleanser a good fit because they gently wash away dirt and calm the skin without causing irritation. To truly clear acne-prone skin, a cleanser of this type needs soothing and gentle ingredients that actively target blemishes and breakouts while keeping the skin balanced.
Sources: [Journal of Cosmetic Science, 2007](https://pubmed.ncbi.nlm.nih.gov/17598025/), [Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/)

### What does Sodium Cocoyl Isethionate do for acne-prone skin?

Sodium cocoyl isethionate helps wash acne-prone skin gently because its large size keeps it from getting deep into the skin to cause irritation or dryness. This ingredient keeps your skin calm and clean while maintaining your skin barrier, which a cleanser for breakouts needs to do without stripping dry or sensitive skin.
Sources: [Journal of Cosmetic Science, 2007](https://pubmed.ncbi.nlm.nih.gov/17598025/), [Dermatologic Therapy, 2004](https://pubmed.ncbi.nlm.nih.gov/14728695/)

### What does Aloe Vera Leaf Juice do for acne-prone skin?

Aloe Vera Leaf Juice helps calm acne-prone skin and may reduce redness, bumps, and spots when used consistently. Studies show it helps clear breakouts and keeps skin smooth by fighting blemish-causing factors.
Sources: [Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/), [The Journal of Dermatological Treatment, 2014](https://pubmed.ncbi.nlm.nih.gov/23336746/)

### Where does it go in a skincare routine for acne-prone skin?

This enzyme powder cleanser goes in your weekly routine, used once a week as an exfoliating step after your cleanser. While it is safe and gentle for your skin, it does not directly target acne and breakouts, so a product for this skin needs active blemish-fighting ingredients like salicylic acid or benzoyl peroxide.

### Can I use this cleanser with retinol, and in what order?

You can use this cleanser in your routine when using retinol, applying it in the evening before your retinol treatment. It is unlikely to irritate your skin, but an acne-prone skin routine needs targeted ingredients like salicylic acid or benzoyl peroxide to directly treat breakouts and blemishes.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/), [American Family Physician, 2012](https://pubmed.ncbi.nlm.nih.gov/23062156/)

### How often should I use it?

Start by using this enzyme powder cleanser once a week as part of your routine. If your skin tolerates it well and you see good results, you may carefully use it more often.

### Can this cleanser clog pores, cause breakouts or purging for acne-prone skin?

CELL BY CELL Soft Enzyme Powder is unlikely to clog pores or cause breakouts on acne-prone skin because it contains gentle cleansers like Sodium Cocoyl Isethionate and soothing ingredients like Aloe Barbadensis Leaf Juice. However, since the formula does not directly target acne, blemishes, or breakouts, skin prone to breakouts generally needs a cleanser with targeted acne-fighting ingredients like salicylic acid or benzoyl peroxide.
Sources: [Journal of Cosmetic Science, 2007](https://pubmed.ncbi.nlm.nih.gov/17598025/)

### Is it fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for acne-prone skin

- [By Wishtrend Green Tea & Enzyme Powder Wash](https://lovi.care/skincare/fr/p/by-wishtrend/green-tea-and-enzyme-powder-wash/for/acne-prone-skin) — High fit — €16.71 at Amazon
- [NEEDLY Mild Enzyme Cleansing Powder](https://lovi.care/skincare/fr/p/needly/mild-enzyme-cleansing-powder/for/acne-prone-skin) — High fit — €39.00 at Amazon
- [VT Cica Mild Powder Wash](https://lovi.care/skincare/fr/p/vt/cica-mild-powder-wash/for/acne-prone-skin) — Superior fit — €5.00 at Notino

## Pairs well with

- Cleanser: [B.LAB Matcha Hydrating Foam Cleanser](https://lovi.care/skincare/fr/p/b-lab/matcha-hydrating-foam-cleanser/for/acne-prone-skin) — Superior fit — €13.98 at Amazon
- Hydrating Toner: [La Mer The Tonic](https://lovi.care/skincare/fr/p/la-mer/the-tonic/for/acne-prone-skin) — Superior fit — €10.25 at Amazon
- Moisturizer: [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/fr/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/acne-prone-skin) — Superior fit — €17.90 at Amazon

## Where to buy

No store in France has a checked price for this product, so the page shows none.

## Ingredients

Zea Mays Starch, Sodium Cocoyl Isethionate, Sodium Lauroyl Glutamate, Aloe Barbadensis Leaf Juice, Opuntia Ficus-Indica Stem Extract, Allantoin, Collagen, Sorbitol, Ascorbyl Palmitate, Isopropyl Palmitate, Grapefruit Seed Extract, Pollen Extract, Titanium Dioxide, Citric Acid, Disodium Edta
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/cell-by-cell/soft-enzyme-powder/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/cell-by-cell/soft-enzyme-powder/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/cell-by-cell/soft-enzyme-powder/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/cell-by-cell/soft-enzyme-powder/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/cell-by-cell/soft-enzyme-powder/for/acne-prone-skin (this page)
- Italy: https://lovi.care/skincare/it/p/cell-by-cell/soft-enzyme-powder/for/acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/cell-by-cell/soft-enzyme-powder/for/acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/cell-by-cell/soft-enzyme-powder/for/acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/cell-by-cell/soft-enzyme-powder/for/acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/cell-by-cell/soft-enzyme-powder/for/acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/cell-by-cell/soft-enzyme-powder/for/acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/cell-by-cell/soft-enzyme-powder/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/cell-by-cell/soft-enzyme-powder/for/acne-prone-skin