# Biossance Squalane + Vitamin C Dark Spot Serum for oily skin

**Lovi Fit: High fit for oily skin.**
Oily Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/fr/p/biossance/squalane-vitamin-c-dark-spot-serum/for/oily-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for France.

Brand: [Biossance](https://lovi.care/skincare/fr/brands/biossance)
Category: [Serums and treatments](https://lovi.care/skincare/fr/best/serums)

This fit is calculated for the concerns frequently associated with oily skin: shine, enlarged pores, blackheads, and blemishes. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for oily skin; a few serums fit it even better.

## Why this fit

- Offers moderate brightening for your oily skin due to 3-O-Ethyl Ascorbic Acid and Glycyrrhiza Glabra Root Extract, which help regulate melanogenesis and provide antioxidant activity.
- While the serum offers general hydration benefits, its primary function is not directly targeted at managing oily shine.
- The formula is safe for your oily skin, with no risks of irritation from harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/fr/p/biossance/squalane-vitamin-c-dark-spot-serum/for/oily-skin): High (this page)
- [Dry skin](https://lovi.care/skincare/fr/p/biossance/squalane-vitamin-c-dark-spot-serum/for/dry-skin): Superior
- [Combination skin](https://lovi.care/skincare/fr/p/biossance/squalane-vitamin-c-dark-spot-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/fr/p/biossance/squalane-vitamin-c-dark-spot-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/fr/p/biossance/squalane-vitamin-c-dark-spot-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/fr/p/biossance/squalane-vitamin-c-dark-spot-serum/for/dark-spots): Superior
- [Mature skin](https://lovi.care/skincare/fr/p/biossance/squalane-vitamin-c-dark-spot-serum/for/mature-skin): Superior
- [Dry sensitive skin](https://lovi.care/skincare/fr/p/biossance/squalane-vitamin-c-dark-spot-serum/for/dry-sensitive-skin): Superior
- [Oily acne-prone skin](https://lovi.care/skincare/fr/p/biossance/squalane-vitamin-c-dark-spot-serum/for/oily-acne-prone-skin): Superior

## Key ingredients

Ascorbic Acid, Squalane, White Shiitake Mushroom Extract, Licorice Root Extract, Sodium Hyaluronate

## What the research says

- A multi-component dissolving microneedle patch loaded with glabridin, 3-O-ethyl-L-ascorbic acid, and tranexamic acid effectively reduced chloasma and age spots while demonstrating safety in clinical evaluation, alongside significant antioxidant, anti-tyrosinase, and melanin-reduction effects in vitro and in vivo. ([Polymers, 2023](https://pubmed.ncbi.nlm.nih.gov/37571190/))
- A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/))
- Licochalcone A activated Nrf2 signaling, elevated cytoprotective enzymes, increased the reduced-to-oxidized glutathione ratio, and decreased reactive oxygen species in human fibroblasts and neutrophils, while a LicA-rich licorice extract lowered UVA-induced oxidative processes in vivo. ([Experimental Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25381913/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))
- Lentinan reduced benzo(a)pyrene-induced oxidative stress, malondialdehyde levels, and inflammatory cytokine production while increasing antioxidant enzyme activities in human keratinocytes. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31135098/))
- Shiitake mushroom ethanol extract exhibited moderate antioxidant capacity, 51.99% elastase inhibition, concentration-dependent collagenase suppression, and non-toxicity in human keratinocytes, supporting its safe incorporation into stable topical anti-aging skin-care formulations. ([Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41656649/))
- Combining 755 nm alexandrite laser with topical licorice gel significantly reduces terminal hair counts compared to alexandrite laser with placebo in women with idiopathic hirsutism. ([Evidence-based Complementary and Alternative Medicine, 2015](https://pubmed.ncbi.nlm.nih.gov/26273313/))
- Bioactive glycyrrhizic acid and oxymatrine ionic liquid self-assembled nanomicelles significantly promoted the transdermal permeation, subcutaneous retention, and anti-photoaging efficacy of palmitoyl pentapeptide-4 in cellular and animal models compared to unformulated peptide. ([Advanced Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39783908/))
- Topical application of Glycyrrhiza glabra and Sophora japonica flavonoid-rich fractions individually and in combination significantly increased the wound healing rate and reduced oxidative stress compared to wound and Nolaver-treated groups. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37049756/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))

## What reviewers say

Based on a very large amount of data, this serum is frequently praised for its lightweight, milky texture that hydrates while effectively brightening dull complexions and fading acne scars over time. Many with sensitive skin find it gentle and non-irritating, although a subset of users experienced no visible changes in pigmentation or suffered severe allergic reactions like redness and swelling.

- Liked: Brightens complexion (mostly mentioned)
- Liked: Fades dark spots (often mentioned)
- Liked: Hydrating texture (often mentioned)
- Liked: Gentle formula (sometimes noted)
- Disliked: High price (sometimes noted)
- Disliked: No visible results (sometimes noted)
- Disliked: Allergic reactions (rarely noted)
- Disliked: Poor packaging (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week and build up to daily use if your skin tolerates it well.
- Apply the serum after cleansing and toning, but right before your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin. Let it absorb ⏱ for a minute before applying the next product.
- Apply the serum on clean and dry skin since your skin is not sensitive and you want to target oily shine. This helps control excess oil throughout the night.
- Avoid the delicate eye area and do a patch test before using the serum for the very first time.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Biossance Squalane + Vitamin C Dark Spot Serum a great fit for oily skin?

This serum is a great fit for your oily skin because it offers moderate brightening using vitamin C and licorice root extract to help even out skin tone. It also has a safe formula that is unlikely to cause irritation while providing light hydration.
Sources: [Polymers, 2023](https://pubmed.ncbi.nlm.nih.gov/37571190/), [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/)

### Which ingredients make this serum a good fit for oily skin?

This serum is a great fit for your oily skin because 3-O-Ethyl Ascorbic Acid and licorice root extract help brighten dark spots and provide antioxidant care. These ingredients work safely to improve skin tone without causing irritation or adding heavy shine.
Sources: [Polymers, 2023](https://pubmed.ncbi.nlm.nih.gov/37571190/)

### What does Vitamin C do for oily skin?

Vitamin C helps brighten skin tone and smooth texture while providing antioxidant protection that prevents sebum oxidation. For oily skin, this type of product typically needs to be paired with oil-controlling or pore-clearing ingredients like salicylic acid or plant extracts.
Sources: [International Journal of Cosmetic Science, 2005](https://pubmed.ncbi.nlm.nih.gov/18492184/)

### What does Squalane do for oily skin?

Squalane helps keep oily skin soft and smooth without feeling heavy, though oxidized forms may sometimes trigger irritation. To work well for oily skin, this type of product needs lightweight, non-clogging ingredients that balance moisture without adding excess grease.
Sources: [The Journal of Investigative Dermatology, 2006](https://pubmed.ncbi.nlm.nih.gov/16778793/)

### Where does this serum go in a skincare routine for oily skin?

This serum goes in your evening routine, applied after cleansing and toning and before your moisturizer. Putting treatments in the evening keeps things simple and helps avoid extra safety concerns around sun exposure.

### Can I use this serum with retinol, and in what order?

You can use this treatment alongside a retinol, applying the treatment first in your evening routine and following with your retinol and moisturizer. This serum is a great fit for your oily skin and helps brighten without clogging pores or causing irritation.

### How often should I use this serum?

You can use this treatment in your evening routine for simplicity and extra safety around sun exposure. It is safe for your oily skin, with no risks of irritation from harsh ingredients.
Sources: [Facial Plastic Surgery, 2014](https://pubmed.ncbi.nlm.nih.gov/24488631/)

### Can this serum clog pores, cause breakouts or purging for oily skin?

Biossance Squalane + Vitamin C Dark Spot Serum is safe for oily skin and is unlikely to cause breakouts or clog pores, as its formula avoids harsh ingredients that trigger irritation. It helps brighten dark spots while keeping skin balanced without heavy oils.
Sources: [Polymers, 2023](https://pubmed.ncbi.nlm.nih.gov/37571190/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for oily skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/fr/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/oily-skin) — Superior fit — €18.25 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/fr/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/oily-skin) — Superior fit — €35.99 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/fr/p/skinceuticals/c-e-ferulic/for/oily-skin) — High fit — €139.99 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/fr/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — €11.35 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/fr/p/some-by-mi/snail-truecica-miracle-repair-toner/for/oily-skin) — Superior fit — €19.99 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/fr/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/oily-skin) — Superior fit — €17.47 at Amazon

## Where to buy

No store in France has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, 3-O-Ethyl Ascorbic Acid, Squalane, Lentinus Edodes Mycelium Extract, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Glycyrrhiza Glabra Root Extract Licorice Root Extract, Sodium Hyaluronate, Citric Acid, Polyacrylate Crosspolymer-6, Acacia Senegal Gum, Xanthan Gum, Sodium Gluconate, Sodium Citrate, Phenoxyethanol, Ethylhexylglycerin
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/biossance/squalane-vitamin-c-dark-spot-serum/for/oily-skin
- United Kingdom: https://lovi.care/skincare/uk/p/biossance/squalane-vitamin-c-dark-spot-serum/for/oily-skin
- Ireland: https://lovi.care/skincare/ie/p/biossance/squalane-vitamin-c-dark-spot-serum/for/oily-skin
- Germany: https://lovi.care/skincare/de/p/biossance/squalane-vitamin-c-dark-spot-serum/for/oily-skin
- France: https://lovi.care/skincare/fr/p/biossance/squalane-vitamin-c-dark-spot-serum/for/oily-skin (this page)
- Italy: https://lovi.care/skincare/it/p/biossance/squalane-vitamin-c-dark-spot-serum/for/oily-skin
- Netherlands: https://lovi.care/skincare/nl/p/biossance/squalane-vitamin-c-dark-spot-serum/for/oily-skin
- Spain: https://lovi.care/skincare/es/p/biossance/squalane-vitamin-c-dark-spot-serum/for/oily-skin
- Canada: https://lovi.care/skincare/ca/p/biossance/squalane-vitamin-c-dark-spot-serum/for/oily-skin
- Australia: https://lovi.care/skincare/au/p/biossance/squalane-vitamin-c-dark-spot-serum/for/oily-skin
- Singapore: https://lovi.care/skincare/sg/p/biossance/squalane-vitamin-c-dark-spot-serum/for/oily-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/biossance/squalane-vitamin-c-dark-spot-serum/for/oily-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/biossance/squalane-vitamin-c-dark-spot-serum/for/oily-skin