# BIOEFFECT EGF Serum for dry sensitive skin

**Lovi Fit: Superior fit for dry sensitive skin.**
Dry Skin Fit: Superior · Effectiveness: Superior · Safety: Excellent.

Page: https://lovi.care/skincare/fr/p/bioeffect/egf-serum/for/dry-sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for France.

Brand: [BIOEFFECT](https://lovi.care/skincare/fr/brands/bioeffect)
Category: [Serums and treatments](https://lovi.care/skincare/fr/best/serums)

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best serums for dry sensitive skin.

## Why this fit

- Excellent suitability for your dry and sensitive skin as Glycerin and Sodium Hyaluronate provide superior hydration and humectant action, ideal for combating dryness and flakiness.
- The high concentrations of Rh-Oligopeptide-1 and Barley Sh-Oligopeptide-1 further enhance skin regeneration, plumping fine lines and wrinkles for a smoother appearance.
- The product is safe for your skin, containing no harsh ingredients and featuring soothing components that minimize irritation risk.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/fr/p/bioeffect/egf-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/fr/p/bioeffect/egf-serum/for/dry-skin): Superior
- [Combination skin](https://lovi.care/skincare/fr/p/bioeffect/egf-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/fr/p/bioeffect/egf-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/fr/p/bioeffect/egf-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/fr/p/bioeffect/egf-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/fr/p/bioeffect/egf-serum/for/mature-skin): Superior
- [Dry sensitive skin](https://lovi.care/skincare/fr/p/bioeffect/egf-serum/for/dry-sensitive-skin): Superior (this page)
- [Oily acne-prone skin](https://lovi.care/skincare/fr/p/bioeffect/egf-serum/for/oily-acne-prone-skin): High

## Key ingredients

Rh-Oligopeptide-1, Glycerin, Sodium Hyaluronate, Hordeum Vulgare Seed Extract, Tromethamine

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical epidermal growth factor combined with silver sulfadiazine accelerated the rate of epidermal regeneration and significantly decreased healing time by approximately 1 to 1.5 days across all stages of healing in skin-graft-donor sites of 12 patients compared to silver sulfadiazine alone. ([The New England Journal of Medicine, 1989](https://pubmed.ncbi.nlm.nih.gov/2659995/))
- Topical recombinant human epidermal growth factor combined with ablative fractional carbon dioxide laser significantly improved striae surface texture and showed significantly greater participant satisfaction regarding marked improvement compared to ablative fractional carbon dioxide laser combined with Aloe vera gel in patients with striae alba. ([Lasers in Surgery and Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/30614013/))
- Topical EGF combined with fractional CO2 laser significantly improves the clinical appearance of atrophic acne scars and decreases skin pigmentation compared to fractional CO2 laser alone in patients with atrophic acne scars. ([The Journal of Clinical and Aesthetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35942017/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Lidocaine at 20% and lidocaine 10% with trometamol provided effective pain control comparable to lidocaine/prilocaine in healthy adults after a 60-minute exposure, while propylene glycol did not accelerate the onset of analgesia. ([Journal of Pain Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28546768/))
- A Tris/Arg-formulated cleanser significantly decreased noninflammatory and inflammatory acne and pore size with keratotic plugs compared to an AEC/AC cleanser in male Thai subjects with mild to moderate acne over 4 weeks. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31347768/))
- Ketorolac tromethamine poloxamer hydrogel provided sufficient bioavailability to reach the site of action with anti-inflammatory efficacy and no visual skin irritation in volunteers. ([Pharmaceutical Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28540502/))

## What reviewers say

Users with dry, mature, or dehydrated skin highly praise this serum for its deep hydration, plumping effects, and ability to reduce fine lines, resulting in a radiant complexion. Some users with oily or combination skin find the texture sticky or heavy.

- Liked: Hydrating and plumping (mostly mentioned)
- Liked: Radiant glow (often mentioned)
- Liked: Reduces fine lines (often mentioned)
- Disliked: Expensive product (often mentioned)
- Liked: Improves texture (sometimes noted)
- Disliked: Sticky texture (sometimes noted)
- Disliked: Too heavy (rarely noted)

## How to apply

- Use this PM routine for your evening skincare. Start using the serum 3 times a week and increase to daily use if your skin feels comfortable.
- Apply the serum after cleansing and toner, but right before your moisturizer. This step locks in deep hydration for dry skin.
- Gently press 2-3 drops of the serum into your skin using your palms. Let it absorb completely for a minute ⏱ before applying your next product.
- Since your skin is sensitive, apply the serum on completely dry skin for better tolerance and less irritation.
- Avoid the sensitive eye area during application. Always do a patch test before your first use to ensure your skin reacts well.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes BIOEFFECT EGF Serum one of the best fits for dry sensitive skin?

This serum is one of the best fits because glycerin and sodium hyaluronate provide deep hydration to combat dryness and flakiness on dry sensitive skin. It also contains high concentrations of skin-regenerating ingredients that help plump fine lines for a smoother look while keeping irritation risk low.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for dry sensitive skin?

Glycerin and Sodium Hyaluronate make this serum a great fit by providing deep hydration to fight dryness and flakiness, while soothing components help keep your skin calm and comfortable.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does EGF do for dry sensitive skin?

EGF helps calm dry sensitive skin by supporting skin repair and renewal, though it may need to be paired with rich moisturizers and soothing ingredients to properly comfort very dry or reactive areas.
Sources: [International Journal of Molecular Medicine, 2017](https://pubmed.ncbi.nlm.nih.gov/28204807/)

### What does Glycerin do for dry sensitive skin?

Glycerin helps dry sensitive skin by drawing moisture into the skin and keeping it there, making the skin soft and smooth. It is very gentle and unlikely to cause irritation while improving how well the skin holds onto water. This type of skin needs ingredients that boost hydration and repair the barrier without causing stinging.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [The British Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18510666/)

### Where does this serum go in a skincare routine for dry sensitive skin?

This serum goes in the evening routine after your cleansing and toning steps, followed by a moisturizer. Applying treatments at night helps keep things simple and provides extra safety around sun exposure.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first to help keep your dry, sensitive skin calm and hydrated before layering retinol on top. This approach helps reduce the likelihood of irritation while supporting skin regeneration and a smooth feel.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### How often should I use this serum?

This treatment is used in the evening as part of your routine. It helps keep dry and sensitive skin calm and hydrated without harsh ingredients.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can this serum clog pores, cause breakouts or purging for dry sensitive skin?

This serum is unlikely to clog pores or cause breakouts on dry sensitive skin, as it contains no harsh ingredients and features a safe formula designed to minimize irritation. Its hydrating and soothing components help keep skin comfortable without heavy oils that typically trigger blemishes.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

## Alternatives for dry sensitive skin

- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/fr/p/skinceuticals/c-e-ferulic/for/dry-sensitive-skin) — Superior fit — €139.99 at Amazon
- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/fr/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/dry-sensitive-skin) — Superior fit — €57.00 at Amazon
- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/fr/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/dry-sensitive-skin) — Superior fit — €18.25 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/fr/p/cerave/hydrating-facial-cleanser/for/dry-sensitive-skin) — Superior fit — €7.50 at Amazon
- Soothing Toner: [SKIN1004 Centella Asiatica Toning Toner](https://lovi.care/skincare/fr/p/skin1004/centella-asiatica-toning-toner/for/dry-sensitive-skin) — Superior fit — €18.79 at Amazon
- Moisturizer with Sun Protection: [d'Alba UVessence Mild Waterfull Sun Cream SPF 50](https://lovi.care/skincare/fr/p/d-alba/uvessence-mild-waterfull-sun-cream-spf-50/for/dry-sensitive-skin) — Superior fit — €29.95 at Amazon

## Where to buy

No store in France has a checked price for this product, so the page shows none.

## Ingredients

Glycerin, Water, Sodium Hyaluronate, Tromethamine, Sodium Chloride, Hordeum Vulgare Seed Extract, Rh-Oligopeptide-1 Barley Sh-Oligopeptide-1
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/bioeffect/egf-serum/for/dry-sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/bioeffect/egf-serum/for/dry-sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/bioeffect/egf-serum/for/dry-sensitive-skin
- Germany: https://lovi.care/skincare/de/p/bioeffect/egf-serum/for/dry-sensitive-skin
- France: https://lovi.care/skincare/fr/p/bioeffect/egf-serum/for/dry-sensitive-skin (this page)
- Italy: https://lovi.care/skincare/it/p/bioeffect/egf-serum/for/dry-sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/bioeffect/egf-serum/for/dry-sensitive-skin
- Spain: https://lovi.care/skincare/es/p/bioeffect/egf-serum/for/dry-sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/bioeffect/egf-serum/for/dry-sensitive-skin
- Australia: https://lovi.care/skincare/au/p/bioeffect/egf-serum/for/dry-sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/bioeffect/egf-serum/for/dry-sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/bioeffect/egf-serum/for/dry-sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/bioeffect/egf-serum/for/dry-sensitive-skin