# Bioderma Hydrabio Serum for oily acne-prone skin

**Lovi Fit: High fit for oily acne-prone skin.**
Oily Skin Fit: Average · Effectiveness: Average · Safety: Excellent.

Page: https://lovi.care/skincare/fr/p/bioderma/hydrabio-serum/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for France.

Brand: [Bioderma](https://lovi.care/skincare/fr/brands/bioderma)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/fr/best/moisturizers)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for oily acne-prone skin; a few moisturizers fit it even better.

## Why this fit

- Offers excellent moisturizing for your oily skin, as glycerin and sodium hyaluronate provide hydration and plumpness without exacerbating oiliness.
- Niacinamide and Laminaria Ochroleuca Extract offer soothing benefits, supporting general skin health though not specifically targeting your acne and breakouts.
- The product is safe for your oily skin, with no risks of irritation due to the absence of harsh ingredients and the presence of calming components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/fr/p/bioderma/hydrabio-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/fr/p/bioderma/hydrabio-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/fr/p/bioderma/hydrabio-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/fr/p/bioderma/hydrabio-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/fr/p/bioderma/hydrabio-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/fr/p/bioderma/hydrabio-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/fr/p/bioderma/hydrabio-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/fr/p/bioderma/hydrabio-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/fr/p/bioderma/hydrabio-serum/for/oily-acne-prone-skin): High (this page)

## Key ingredients

Aquagenium Patent, Sodium Hyaluronate, Niacinamide, Glycerin, Laminaria Ochroleuca Extract

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))

## What reviewers say

Based on a very large amount of data, users consistently praise this serum for its lightweight, gel-like texture that delivers deep hydration without leaving a sticky residue, making it ideal for dehydrated and sensitive skin. While most find it plumps and smooths the complexion effectively, those with extremely dry skin often note it works best when layered under a richer moisturizer rather than as a standalone solution.

- Liked: Lightweight & fast-absorbing (mostly mentioned)
- Liked: Deep hydration (often mentioned)
- Liked: Excellent makeup base (sometimes noted)
- Liked: Sensitive skin friendly (sometimes noted)
- Disliked: Fragrance presence (sometimes noted)
- Disliked: Price vs. size (sometimes noted)
- Disliked: Availability issues (rarely noted)
- Disliked: Not enough for dry skin (rarely noted)

## How to apply

- Use this AM and PM routine every day to help clear your skin. Always remember to finish with SPF in the morning.
- Apply the moisturizer after your cleanser and toner, right before your SPF during the day.
- Gently press a small amount into your skin and avoid rubbing to keep pores clear.
- Apply on clean, slightly damp skin to help the product absorb better and control oil.
- Avoid the sensitive eye area and do a simple patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes Bioderma Hydrabio Serum a great fit for oily acne-prone skin?

Bioderma Hydrabio Serum is a great fit because glycerin and sodium hyaluronate provide hydration and plumpness without making your skin oily. Niacinamide and Laminaria Ochroleuca Extract also help soothe the skin, and the formula is unlikely to cause irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for oily acne-prone skin?

Glycerin and sodium hyaluronate make this serum a great fit by providing deep hydration without adding extra oil to your skin. Niacinamide and Laminaria Ochroleuca Extract also help soothe the skin safely without causing irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Aquagenium Patent do for oily acne-prone skin?

Aquagenium Patent helps oily acne-prone skin by boosting hydration and teaching the skin to hold onto the moisture it naturally makes. This keeps the skin soft and balanced without clogging pores or feeling heavy.

### What does Hyaluronic Acid do for oily acne-prone skin?

Hyaluronic acid helps calm oily acne-prone skin by reducing sebum production and lipid synthesis in sebaceous glands. It also supports skin barrier function and improves hydration while helping deliver treatments without causing irritation.
Sources: [The Journal of Investigative Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28163068/), [Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35796638/)

### Where does this serum go in a skincare routine for oily acne-prone skin?

This serum goes in the evening routine after cleansing and toning, followed by your moisturizer. Putting treatments in the evening keeps things simple and adds extra safety around sun exposure.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first to keep your skin hydrated and calm while retinol works. Using a hydrating moisturizer like this helps lower the chances of irritation and dryness when using strong acne treatments.
Sources: [Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37276158/), [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use this serum?

You can use this treatment in your evening routine for simplicity and extra safety around sun exposure, though it may also be used in the morning or twice a day if desired. Glycerin and sodium hyaluronate provide hydration and plumpness without making your skin oily, while niacinamide and Laminaria Ochroleuca Extract offer soothing benefits.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this serum clog pores, cause breakouts or purging for oily acne-prone skin?

Bioderma Hydrabio Serum is unlikely to clog pores or cause breakouts on oily acne-prone skin, as glycerin and sodium hyaluronate provide lightweight hydration without adding excess oil. The formula is safe and gentle for this skin type, with no harsh ingredients that typically trigger irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this serum around the eyes or on my body?

You can safely use this moisturizing treatment on the thin skin around the eyes and on the body because its gentle formula provides deep hydration without irritation. The skin on the body and around the eyes benefits from lightweight, soothing ingredients like glycerin and sodium hyaluronate to keep areas smooth and comfortable.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Is this serum fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (parfum).

## Alternatives for oily acne-prone skin

- [COSRX Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/fr/p/cosrx/advanced-snail-96-mucin-power-essence/for/oily-acne-prone-skin) — Superior fit — €14.90 at Amazon
- [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/fr/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/oily-acne-prone-skin) — Superior fit — €17.90 at Amazon
- [innisfree Green Tea Seed Hyaluronic Acid Hydrating Serum](https://lovi.care/skincare/fr/p/innisfree/green-tea-seed-hyaluronic-acid-hydrating-serum/for/oily-acne-prone-skin) — Superior fit — €29.00 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/fr/p/cerave/foaming-facial-cleanser/for/oily-acne-prone-skin) — Superior fit — €11.35 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/fr/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-acne-prone-skin) — Superior fit — €36.00 at Amazon
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/fr/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/oily-acne-prone-skin) — Superior fit — €34.30 at Amazon

## Where to buy

- Amazon.fr: €27.97 (https://www.amazon.fr/dp/B077GNPDX8?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1)
- Notino: €26.90 (https://www.notino.fr/bioderma/hydrabio-serum-serum-visage-pour-peaux-deshydratees/p-406040/)
- Lookfantastic: €31.28 (https://www.lookfantastic.fr/p/bioderma-hydrabio-hyalu-face-serum-for-dry-dehydrated-skin-with-hyaluronic-acid-and-niacinamide-30ml/14939661/)
Prices checked 10 Oct – 5 Nov 2026.

## Ingredients

Water, Glycerin, Xylitol, Sodium Polyacrylate, Mannitol, Rhamnose, Fructooligosaccharides, Laminaria Ochroleuca Extract, Niacinamide, Pyrus Malus Fruit Extract, Dimethicone, Cyclopentasiloxane, Trideceth-6, Peg Ppg-18 18 Dimethicone, Sodium Hyaluronate, Hexyldecanol, Caprylic Capric Triglyceride, Disodium Edta, Chlorphenesin, Phenoxyethanol, Parfum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/bioderma/hydrabio-serum/for/oily-acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/bioderma/hydrabio-serum/for/oily-acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/bioderma/hydrabio-serum/for/oily-acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/bioderma/hydrabio-serum/for/oily-acne-prone-skin
- France: https://lovi.care/skincare/fr/p/bioderma/hydrabio-serum/for/oily-acne-prone-skin (this page)
- Italy: https://lovi.care/skincare/it/p/bioderma/hydrabio-serum/for/oily-acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/bioderma/hydrabio-serum/for/oily-acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/bioderma/hydrabio-serum/for/oily-acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/bioderma/hydrabio-serum/for/oily-acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/bioderma/hydrabio-serum/for/oily-acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/bioderma/hydrabio-serum/for/oily-acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/bioderma/hydrabio-serum/for/oily-acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/bioderma/hydrabio-serum/for/oily-acne-prone-skin