# Anua Niacinamide 10% + TXA 4% Serum for sensitive skin

**Lovi Fit: Average fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: Low Risk.

Page: https://lovi.care/skincare/fr/p/anua/niacinamide-10-txa-4-serum/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for France.

Brand: [Anua](https://lovi.care/skincare/fr/brands/anua)
Category: [Serums and treatments](https://lovi.care/skincare/fr/best/serums)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for sensitive skin; other serums fit it better.

## Why this fit

- Offers moderate brightening and evening of skin tone, which is supportive for your redness and irritation, due to the presence of niacinamide and tranexamic acid in moderate concentrations.
- The inclusion of panthenol and allantoin provides mild soothing effects, and the formula is highly suitable for normal skin due to niacinamide and glycerin offering good humectant action and barrier repair.
- The product is generally safe for your sensitive skin, with a low risk of irritation due to the absence of harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/fr/p/anua/niacinamide-10-txa-4-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/fr/p/anua/niacinamide-10-txa-4-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/fr/p/anua/niacinamide-10-txa-4-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/fr/p/anua/niacinamide-10-txa-4-serum/for/sensitive-skin): Average (this page)
- [Acne-prone skin](https://lovi.care/skincare/fr/p/anua/niacinamide-10-txa-4-serum/for/acne-prone-skin): Superior
- [Skin with dark spots](https://lovi.care/skincare/fr/p/anua/niacinamide-10-txa-4-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/fr/p/anua/niacinamide-10-txa-4-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/fr/p/anua/niacinamide-10-txa-4-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/fr/p/anua/niacinamide-10-txa-4-serum/for/oily-acne-prone-skin): Superior

## Key ingredients

Niacinamide, Txa Tranexamic Acid, Hyaluronic Acid, Panthenol, Allantoin

## What the research says

- Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans. ([Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/))
- Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two. ([Auris, Nasus, Larynx, 2020](https://pubmed.ncbi.nlm.nih.gov/32067777/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment. ([Aesthetic Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29948103/))

## What reviewers say

Based on a very large amount of data, this serum is highly effective at fading post-acne marks and evening out skin tone, with many users reporting a radiant glow within weeks. While generally well-tolerated and hydrating for many, a significant number of users find the serum leaves a sticky residue, and a smaller portion experience breakouts or irritation, possibly due to the high niacinamide concentration.

- Liked: Fades dark spots (mostly mentioned)
- Liked: Brightens skin (often mentioned)
- Disliked: Sticky finish (often mentioned)
- Liked: Hydrating (sometimes noted)
- Liked: Improves texture (sometimes noted)
- Disliked: Caused breakouts (sometimes noted)
- Disliked: Caused irritation (rarely noted)
- Disliked: Slow results (rarely noted)

## How to apply

- Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
- Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
- Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
- Always do a patch test before your first use and avoid getting the serum too close to your eyes .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Anua Niacinamide 10% + TXA 4% Serum work for sensitive skin?

This serum works for sensitive skin, though other products fit it better. It helps calm redness and even out skin tone with a low risk of irritation, but a product for this skin needs stronger soothing and skin-repairing ingredients without harsh additives to deliver optimal results.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/)

### Which ingredients make this serum a good fit for sensitive skin?

Niacinamide and tranexamic acid help even out skin tone and calm redness, while panthenol and allantoin provide mild soothing effects for sensitive skin. This serum works for your skin, though products rated higher for sensitive skin need extra antioxidants and deeply calming ingredients that soothe irritation without any risk.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### What does Niacinamide do for sensitive skin?

Niacinamide helps calm sensitive skin by strengthening the skin barrier and reducing redness and irritation. It is very well tolerated and may improve overall comfort and resilience with regular use.
Sources: [Cutis, 2005](https://pubmed.ncbi.nlm.nih.gov/16209160/), [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/)

### What does Tranexamic Acid do for sensitive skin?

Tranexamic acid helps calm sensitive skin by strengthening the skin barrier and reducing redness and flushing. It is unlikely to cause severe reactions, making it a well-tolerated choice for reactive or easily irritated skin.
Sources: [International Journal of Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/23967870/), [Clinical, Cosmetic and Investigational Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38895607/)

### Where does this serum go in a skincare routine for sensitive skin?

This serum goes in the evening routine after your cleansing and soothing toner, followed by a moisturizer. Sensitive skin works best with treatment products that include soothing ingredients like panthenol and allantoin alongside gentle brighteners to calm redness and irritation.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first to help calm your skin, followed by your retinol. This product is generally safe with a low risk of irritation for your sensitive skin, but a product for this skin needs extra soothing and barrier-repairing ingredients like panthenol and allantoin to prevent dryness.

### How often should I use this serum?

This serum is used in the evening once a week for sensitive skin, and people who tolerate it well may carefully use it more often. To work best for this skin type, a product needs soothing ingredients like panthenol and allantoin to keep it calm and comfortable.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Can this serum clog pores, cause breakouts or purging for sensitive skin?

This serum may cause breakouts for some people with sensitive skin, as reviewers moderately complain about this issue. To better prevent clogged pores and breakouts, sensitive skin needs a lightweight, non-greasy formula with gentle soothing ingredients and without heavy sticky agents.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for sensitive skin

- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/fr/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/sensitive-skin) — Superior fit — €57.00 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/fr/p/skinceuticals/c-e-ferulic/for/sensitive-skin) — High fit — €139.99 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/fr/p/neogen-dermalogy/real-vitamin-c-serum/for/sensitive-skin) — High fit — €37.67 at Amazon

## Pairs well with

- Cleanser: [La Roche-Posay Hydrating Gentle Cleanser](https://lovi.care/skincare/fr/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/sensitive-skin) — Superior fit — €28.02 at Amazon
- Soothing Toner: [Pixi Milky Tonic](https://lovi.care/skincare/fr/p/pixi/milky-tonic/for/sensitive-skin) — Superior fit — €27.60 at Amazon
- Moisturizer with Sun Protection: [innisfree Daily Mild Sunscreen](https://lovi.care/skincare/fr/p/innisfree/daily-mild-sunscreen/for/sensitive-skin) — Superior fit — €24.00 at Amazon

## Where to buy

- Amazon.fr: €22.50 (https://www.amazon.fr/dp/B0DL92QM79?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1)
- Lookfantastic: €20.24 (https://www.lookfantastic.fr/p/anua-niacinamide-10-txa-4-serum-30ml/16201620/)
- Notino: €30.90 (https://www.notino.fr/anua/niacinamide-10-txa-4-dark-spot-correcting-serum-serum-illuminateur-pour-un-teint-unifie/p-16268710/)
Prices checked 17 Oct – 5 Nov 2026.

## Ingredients

Water, Niacinamide, Glycerin, Butylene Glycol, 1,2-Hexanediol, Betaine, Panthenol, Hyaluronic Acid, Allantoin, Tocopherol, Ethylhexylglycerin, Xanthan Gum, Disodium Edta
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/anua/niacinamide-10-txa-4-serum/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/anua/niacinamide-10-txa-4-serum/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/anua/niacinamide-10-txa-4-serum/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/anua/niacinamide-10-txa-4-serum/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/anua/niacinamide-10-txa-4-serum/for/sensitive-skin (this page)
- Italy: https://lovi.care/skincare/it/p/anua/niacinamide-10-txa-4-serum/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/anua/niacinamide-10-txa-4-serum/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/anua/niacinamide-10-txa-4-serum/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/anua/niacinamide-10-txa-4-serum/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/anua/niacinamide-10-txa-4-serum/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/anua/niacinamide-10-txa-4-serum/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/anua/niacinamide-10-txa-4-serum/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/anua/niacinamide-10-txa-4-serum/for/sensitive-skin