# A+ 345 Relief Cream for acne-prone skin

**Lovi Fit: Average fit for acne-prone skin.**
Combination Skin Fit: High · Effectiveness: Average · Safety: Excellent.

Page: https://lovi.care/skincare/fr/p/a/345-relief-cream/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for France.

Brand: [A+](https://lovi.care/skincare/fr/brands/a)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/fr/best/moisturizers)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for acne-prone skin; other moisturizers fit it better.

## Why this fit

- Offers moderate hydration and soothing benefits for your combination skin, as glycerin and hyaluronic acid provide excellent moisturizing effects while niacinamide and panthenol support barrier repair.
- The inclusion of Centella Asiatica Leaf Extract and Coptis Japonica Root Extract offers additional calming properties suitable for managing blemishes and breakouts.
- The product is safe for your skin, with no reported irritation risks due to its gentle formulation and absence of harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/fr/p/a/345-relief-cream/for/oily-skin): Low
- [Dry skin](https://lovi.care/skincare/fr/p/a/345-relief-cream/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/fr/p/a/345-relief-cream/for/combination-skin): Low
- [Sensitive skin](https://lovi.care/skincare/fr/p/a/345-relief-cream/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/fr/p/a/345-relief-cream/for/acne-prone-skin): Average (this page)
- [Skin with dark spots](https://lovi.care/skincare/fr/p/a/345-relief-cream/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/fr/p/a/345-relief-cream/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/fr/p/a/345-relief-cream/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/fr/p/a/345-relief-cream/for/oily-acne-prone-skin): Average

## Key ingredients

Niacinamide, Hyaluronic Acid, Coptis Japonica Root Extract

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical steroid withdrawal is driven by excess mitochondrial NAD+ metabolism that can be successfully targeted using complex I-inhibiting interventions such as metformin and berberine. ([The Journal of Investigative Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40088241/))
- Topical steroid withdrawal presents as a distinct dermatopathology characterized by burning, flushing, thermodysregulation, and elevated mitochondrial NAD+ oxidation, which can be improved by targeting complex I with metformin or berberine. ([MedRxiv, 2024](https://pubmed.ncbi.nlm.nih.gov/38712043/))
- Hydroxypropyl methylcellulose hydrogel formulations of berberine chloride-loaded escinosomes increased skin residence time and transdermal permeability while maintaining high safety and biocompatibility without skin irritation. ([International Journal of Biological Macromolecules, 2020](https://pubmed.ncbi.nlm.nih.gov/32682035/))

## What reviewers say

Based on a very large amount of data, this lightweight, gel-like cream is widely celebrated by users with oily, combination, and sensitive skin for its ability to soothe redness and fade post-acne marks without clogging pores. However, those with dry skin often find it insufficiently moisturizing, and a subset of users report breakouts or fungal acne triggers despite its soothing claims.

- Liked: Lightweight & fast-absorbing (mostly mentioned)
- Liked: Ideal for oily/combo skin (often mentioned)
- Liked: Soothing & calming (often mentioned)
- Liked: Fades acne marks (sometimes noted)
- Disliked: Not moisturizing enough (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Fungal acne trigger (rarely noted)
- Disliked: Texture/pilling issues (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help keep breakouts under control.
- Apply after your cleanser and toner, and make sure to use your SPF right after in the morning.
- Gently spread a small amount of moisturizer over your face using soft motions. Let it absorb into the skin for a minute before getting dressed or applying makeup.
- Apply on slightly damp skin to help lock in extra moisture. This keeps your combination skin balanced without feeling heavy.
- Avoid the eye area and do a patch test before your first use. Stop using if you feel any irritation.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does A+ 345 Relief Cream work for acne-prone skin?

A+ 345 Relief Cream works for acne-prone skin, though other products fit it better. This moisturizer offers moderate hydration and soothing benefits to help keep your skin calm. A moisturizing treatment for this skin needs effective ingredients that target blemishes without irritation, along with soothing agents and hydrating ingredients to maintain balance.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Which ingredients make this cream a good fit for acne-prone skin?

Niacinamide, hyaluronic acid, panthenol, and centella asiatica leaf extract make this cream a good fit by providing hydration and soothing blemishes without irritation. To work best for acne-prone skin, a moisturizing treatment needs targeted ingredients that clear breakouts, calm redness, and repair the skin barrier without clogging pores or causing irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### What does Niacinamide do for acne-prone skin?

Niacinamide helps acne-prone skin by reducing both inflamed and uninflamed breakouts and calming redness. It is also very helpful for keeping oily skin balanced by cutting down on excess oil production, and it is well tolerated by most people.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38299457/), [Cureus, 2024](https://pubmed.ncbi.nlm.nih.gov/38725769/)

### What does Hyaluronic Acid do for acne-prone skin?

Hyaluronic acid helps acne-prone skin by soothing irritation, calming redness, and keeping the skin balanced without clogging pores. When combined with targeted ingredients like zinc oxide, it may also help reduce breakouts.
Sources: [Biomedicines, 2025](https://pubmed.ncbi.nlm.nih.gov/41007718/), [Drug Delivery, 2017](https://pubmed.ncbi.nlm.nih.gov/28155509/)

### Where does it go in a skincare routine for acne-prone skin?

This moisturizer goes after your hydrating toner in the morning, and after your treatment step in the evening. It provides moderate hydration and calming benefits, though acne-prone skin also needs lightweight, non-clogging formulas with blemish-clearing actives like salicylic acid or tea tree oil for the best fit.
Sources: [International Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/31461548/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this cream with retinol, and in what order?

You can use this cream with retinol, and applying it first helps calm the skin and reduce irritation while your skin adjusts. Acne-prone skin works best with moisturizers that contain ceramides, niacinamide, and soothing plant extracts to support the skin barrier without clogging pores.
Sources: [Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37276158/), [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use it?

You can use this moisturizing treatment twice daily as part of your morning and evening routine. Regular daily application helps keep acne-prone skin balanced and hydrated while supporting barrier repair.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this cream clog pores, cause breakouts or purging for acne-prone skin?

This cream is unlikely to cause breakouts, as it has a gentle formula without harsh ingredients, though a small number of reviewers have reported issues. To properly care for acne-prone skin, a moisturizer of this type needs calming ingredients and lightweight hydrators that keep pores clear while soothing blemishes.

### Can I use it around the eyes or on my body?

You can use this moisturizing treatment around your eyes and on your body because its gentle formula and ingredients like glycerin and hyaluronic acid provide reliable hydration without irritation. However, because skin is thinner around the eyes and varies in thickness across the body, results may differ.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for acne-prone skin

- [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/fr/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/acne-prone-skin) — Superior fit — €17.90 at Amazon
- [COSRX Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/fr/p/cosrx/advanced-snail-96-mucin-power-essence/for/acne-prone-skin) — Superior fit — €14.90 at Amazon
- [belif The True Cream Aqua Bomb](https://lovi.care/skincare/fr/p/belif/the-true-cream-aqua-bomb/for/acne-prone-skin) — High fit — €34.16 at Amazon

## Pairs well with

- Cleanser: [B.LAB Matcha Hydrating Foam Cleanser](https://lovi.care/skincare/fr/p/b-lab/matcha-hydrating-foam-cleanser/for/acne-prone-skin) — Superior fit — €13.98 at Amazon
- Hydrating Toner: [La Mer The Tonic](https://lovi.care/skincare/fr/p/la-mer/the-tonic/for/acne-prone-skin) — Superior fit — €10.25 at Amazon
- SPF: [d'Alba Piedmont Waterfull Mild Sunscreen](https://lovi.care/skincare/fr/p/d-alba/piedmont-waterfull-mild-sunscreen/for/acne-prone-skin) — Superior fit — €16.99 at Amazon

## Where to buy

No store in France has a checked price for this product, so the page shows none.

## Ingredients

Water, Propanediol, Glycerin, Cyclohexasiloxane, 1,2-Hexanediol, Niacinamide, Caprylic Capric Triglyceride, Polyglycerin-3, Panthenol, Polyglyceryl-10 Stearate, Hydrogenated Polydecene, Hydrogenated Poly C6-14 Olefin, Dicaprylyl Carbonate, Ammonium Acryloyldimethyltaurate Vp Copolymer, C14-22 Alcohols, Polymethylsilsesquioxane, C12-20 Alkyl Glucoside, Butylene Glycol, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Ethylhexylglycerin, Polyquaternium-51, Tromethamine, Hyaluronic Acid, Coptis Japonica Root Extract, Houttuynia Cordata Extract, Oenothera Biennis Flower Extract, Beta-Glucan, Resveratrol, Gardenia Florida Fruit Extract, Lavandula Angustifolia Flower Extract Lavender Flower Extract, Opuntia Ficus-Indica Stem Extract, Hydrolyzed Hyaluronic Acid, Centella Asiatica Leaf Extract, Phenoxyethanol, Hibiscus Sabdariffa Flower Extract, Tocopherol, Corallina Officinalis Extract, Ceramide Np
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/a/345-relief-cream/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/a/345-relief-cream/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/a/345-relief-cream/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/a/345-relief-cream/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/a/345-relief-cream/for/acne-prone-skin (this page)
- Italy: https://lovi.care/skincare/it/p/a/345-relief-cream/for/acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/a/345-relief-cream/for/acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/a/345-relief-cream/for/acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/a/345-relief-cream/for/acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/a/345-relief-cream/for/acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/a/345-relief-cream/for/acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/a/345-relief-cream/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/a/345-relief-cream/for/acne-prone-skin