# Lactic acid and betaine

Page: https://lovi.care/skincare/fr/ingredients/lactic-acid-and-betaine

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for France.

Work well together

Use [lactic acid](https://lovi.care/skincare/fr/ingredients/lactic-acid) first, then apply [betaine](https://lovi.care/skincare/fr/ingredients/betaine) to restore moisture since acids can dry skin. Lactic acid gently exfoliates, while betaine replenishes lost [water](https://lovi.care/skincare/fr/ingredients/water) so the skin stays comfortable. If tingling happens, use a lower strength or space them further apart.

[Effects of water activity and low molecular weight humectants on skin permeability and hydration dynamics - a double-blind, randomized and controlled study](https://pubmed.ncbi.nlm.nih.gov/24786192/) [The efficiency of humectants as skin moisturizers in the presence of oil](https://pubmed.ncbi.nlm.nih.gov/11301638/)

- [All about lactic acid](https://lovi.care/skincare/fr/ingredients/lactic-acid)
- [All about betaine](https://lovi.care/skincare/fr/ingredients/betaine)

### [Lactic acid](https://lovi.care/skincare/fr/ingredients/lactic-acid) products

- [Medicube Zero Pore Pad](https://lovi.care/skincare/fr/p/medicube/zero-pore-pad/for/oily-skin) — Superior fit — [€17.15 at Amazon](https://www.amazon.fr/dp/B09V7Z4TJG?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1)
- [First Aid Beauty KP Bump Eraser Body Scrub](https://lovi.care/skincare/fr/p/first-aid-beauty/kp-bump-eraser-body-scrub/for/dark-spots) — Average fit — [€12.65 at Lookfantastic](https://www.lookfantastic.fr/p/first-aid-beauty-kp-bump-eraser-body-scrub-with-10-aha-56.7g/14897216/)
- [EltaMD UV Clear Broad-Spectrum SPF 46](https://lovi.care/skincare/fr/p/eltamd/uv-clear-broad-spectrum-spf-46/for/oily-acne-prone-skin) — Superior fit — [€75.18 at Amazon](https://www.amazon.fr/dp/B00ZPWR0N8?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1)
- [First Aid Beauty Facial Radiance Pads](https://lovi.care/skincare/fr/p/first-aid-beauty/facial-radiance-pads/for/sensitive-skin) — Superior fit — [€41.22 at Amazon](https://www.amazon.fr/dp/B0G8TPX5DR?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1)
- [CeraVe SA Lotion for Rough & Bumpy Skin](https://lovi.care/skincare/fr/p/cerave/sa-lotion-for-rough-and-bumpy-skin/for/oily-skin) — Average fit
- [CeraVe Renewing SA Cream](https://lovi.care/skincare/fr/p/cerave/renewing-sa-cream/for/oily-acne-prone-skin) — High fit
- [The Ordinary Alpha Arbutin 2% + HA](https://lovi.care/skincare/fr/p/the-ordinary/alpha-arbutin-2-ha/for/dark-spots) — Superior fit — [€12.08 at Amazon](https://www.amazon.fr/dp/B06XCZFCFZ?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1)
- [The Ordinary Retinal 0.2% Emulsion](https://lovi.care/skincare/fr/p/the-ordinary/retinal-0-2-emulsion/for/oily-acne-prone-skin) — High fit — [€17.48 at Amazon](https://www.amazon.fr/dp/B0CZ5VG3L1?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1)
- [Kate Somerville ExfoliKate Intensive Exfoliating Treatment](https://lovi.care/skincare/fr/p/kate-somerville/exfolikate-intensive-exfoliating-treatment/for/mature-skin) — Superior fit — [€16.30 at Amazon](https://www.amazon.fr/dp/B076CFBMQZ?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1)
- [Dr. Dennis Gross Alpha Beta Universal Daily Peel](https://lovi.care/skincare/fr/p/dr-dennis-gross/alpha-beta-universal-daily-peel/for/acne-prone-skin) — Superior fit — [€127.62 at Amazon](https://www.amazon.fr/dp/B0CSKS5X7X?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1)
- [The Ordinary Lactic Acid 5% + HA](https://lovi.care/skincare/fr/p/the-ordinary/lactic-acid-5-ha/for/dry-skin) — Superior fit
- [Good Molecules Overnight Exfoliating Treatment](https://lovi.care/skincare/fr/p/good-molecules/overnight-exfoliating-treatment/for/oily-skin) — Superior fit — [€22.99 at Amazon](https://www.amazon.fr/dp/B08TMDRF1L?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1)

### [Betaine](https://lovi.care/skincare/fr/ingredients/betaine) products

- [COSRX Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/fr/p/cosrx/advanced-snail-96-mucin-power-essence/for/dry-skin) — Superior fit — [€14.90 at Amazon](https://www.amazon.fr/dp/B00PBX3L7K?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1)
- [COSRX The Hyaluronic Acid 3 Serum](https://lovi.care/skincare/fr/p/cosrx/the-hyaluronic-acid-3-serum/for/combination-skin) — High fit — [€20.76 at Amazon](https://www.amazon.fr/dp/B09ZYCVH8N?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1)
- [Good Molecules Niacinamide Serum](https://lovi.care/skincare/fr/p/good-molecules/niacinamide-serum/for/oily-skin) — Average fit — [€41.10 at Amazon](https://www.amazon.fr/dp/B0BX32CXP6?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1)
- [COSRX Advanced Snail 92 All in One Cream](https://lovi.care/skincare/fr/p/cosrx/advanced-snail-92-all-in-one-cream/for/sensitive-skin) — Superior fit — [€16.94 at Amazon](https://www.amazon.fr/dp/B01LEJ5MSK?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1)
- [MEDIHEAL Collagen Ampoule Pad](https://lovi.care/skincare/fr/p/mediheal/collagen-ampoule-pad/for/mature-skin) — High fit — [€30.99 at Amazon](https://www.amazon.fr/dp/B0BHVF95S9?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1)
- [PanOxyl Clarifying Exfoliant](https://lovi.care/skincare/fr/p/panoxyl/clarifying-exfoliant/for/combination-skin) — High fit — [€21.60 at Amazon](https://www.amazon.fr/dp/B0CPQ9S5J8?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1)
- [Anua Heartleaf 77% Clear Pad](https://lovi.care/skincare/fr/p/anua/heartleaf-77-clear-pad/for/sensitive-skin) — High fit — [€22.99 at Amazon](https://www.amazon.fr/dp/B08JLMRTZS?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1)
- [innisfree Cherry Blossom Glow Jelly Cream](https://lovi.care/skincare/fr/p/innisfree/cherry-blossom-glow-jelly-cream/for/dry-skin) — Average fit — [€28.00 at Amazon](https://www.amazon.fr/dp/B0F3HGKWN7?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1)
- [The INKEY List Omega Water Cream](https://lovi.care/skincare/fr/p/the-inkey-list/omega-water-cream/for/dry-skin) — High fit — [€9.10 at Amazon](https://www.amazon.fr/dp/B09XY514HX?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1)
- [Illiyoon Ceramide Ato Soothing Gel](https://lovi.care/skincare/fr/p/illiyoon/ceramide-ato-soothing-gel/for/acne-prone-skin) — High fit — [€19.99 at Amazon](https://www.amazon.fr/dp/B081PXPDQ9?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1)
- [COSRX Advanced Snail Mucin Power Sheet Mask](https://lovi.care/skincare/fr/p/cosrx/advanced-snail-mucin-power-sheet-mask/for/dry-skin) — Superior fit
- [AMOREPACIFIC Treatment Enzyme Peel](https://lovi.care/skincare/fr/p/amorepacific/treatment-enzyme-peel/for/dark-spots) — Superior fit

## Questions and answers

### Can you use lactic acid and betaine together?

Yes, you can use [lactic acid](https://lovi.care/skincare/fr/ingredients/lactic-acid) and [betaine](https://lovi.care/skincare/fr/ingredients/betaine) together because the humectant properties of betaine help replenish [water](https://lovi.care/skincare/fr/ingredients/water) content and improve your skin's tolerance to the acid. Lovi rates this combination as Superior for all skin types, especially dry and sensitive skin.

### Which goes first, lactic acid or betaine?

Lovi rates the combination of lactic acid and betaine as working well together.

### Are lactic acid and betaine good for sensitive skin?

Lactic acid and betaine work well together for sensitive skin because betaine is a humectant that helps replenish water and improve skin tolerance while using acids. This combination is beneficial for all skin types, especially dry and sensitive skin.

## Research on lactic acid and betaine

- [Lactate triggers KAT8-mediated LTBP1 lactylation at lysine 752 to promote skin rejuvenation by inducing collagen synthesis in fibroblasts](https://pubmed.ncbi.nlm.nih.gov/39102921/) Lactic acid · International Journal of Biological Macromolecules, 2024
- [Poly-L-Lactic acid increases collagen gene expression and synthesis in cultured dermal fibroblast (Hs68) through the TGF-β/Smad pathway](https://pubmed.ncbi.nlm.nih.gov/36575891/) Lactic acid · Journal of Cosmetic Dermatology, 2023
- [Synergetic Effects of Aloe Vera Extract with Trimethylglycine for Targeted Aquaporin 3 Regulation and Long-Term Skin Hydration](https://pubmed.ncbi.nlm.nih.gov/38611819/) Betaine · Molecules, 2024
- [Formulation of Ascorbic Acid and Betaine-based Therapeutic Deep Eutectic System for Enhanced Transdermal Delivery of Ascorbic Acid](https://pubmed.ncbi.nlm.nih.gov/38794349/) Betaine · Pharmaceutics, 2024
- [Do urea/ammonium lactate combinations achieve better skin protection and hydration than either component alone?](https://pubmed.ncbi.nlm.nih.gov/11803256/) Lactic acid · Skin Pharmacology and Applied Skin Physiology, 2002
- [The use of different concentrations of betaine as a reducing irritation agent in soaps monitored visually and non-invasively](https://pubmed.ncbi.nlm.nih.gov/12535284/) Betaine · Skin Research and Technology, 2003

## Other combinations

- Keep them apart: [Benzoyl peroxide and lactic acid](https://lovi.care/skincare/fr/ingredients/benzoyl-peroxide-and-lactic-acid)
- Keep them apart: [Retinol and lactic acid](https://lovi.care/skincare/fr/ingredients/retinol-and-lactic-acid)
- Depends on the strength: [Niacinamide and lactic acid](https://lovi.care/skincare/fr/ingredients/niacinamide-and-lactic-acid)
- Work well together: [Lactic acid and sodium lactate](https://lovi.care/skincare/fr/ingredients/lactic-acid-and-sodium-lactate)
- Work well together: [Lactic acid and tromethamine](https://lovi.care/skincare/fr/ingredients/lactic-acid-and-tromethamine)
- Work well together: [Acetyl hexapeptide-3 and betaine](https://lovi.care/skincare/fr/ingredients/acetyl-hexapeptide-3-and-betaine)
- Work well together: [Bio-placenta peptides and betaine](https://lovi.care/skincare/fr/ingredients/bio-placenta-peptides-and-betaine)
- Work well together: [Collagen peptide and betaine](https://lovi.care/skincare/fr/ingredients/collagen-peptide-and-betaine)
- Work well together: [Betaine and copper peptide](https://lovi.care/skincare/fr/ingredients/betaine-and-copper-peptide)
- Work well together: [Hexapeptide and betaine](https://lovi.care/skincare/fr/ingredients/hexapeptide-and-betaine)
- Work well together: [Betaine and hexapeptide-9](https://lovi.care/skincare/fr/ingredients/betaine-and-hexapeptide-9)
- Work well together: [Betaine and palmitoyl pentapeptide-4](https://lovi.care/skincare/fr/ingredients/betaine-and-palmitoyl-pentapeptide-4)
- Work well together: [Betaine and palmitoyl tripeptide-1](https://lovi.care/skincare/fr/ingredients/betaine-and-palmitoyl-tripeptide-1)
- Work well together: [Betaine and peptide-rich plasma](https://lovi.care/skincare/fr/ingredients/betaine-and-peptide-rich-plasma)
- Work well together: [Betaine and triple peptide blend](https://lovi.care/skincare/fr/ingredients/betaine-and-triple-peptide-blend)
- Work well together: [AHA blend glycolic and citric acids and betaine](https://lovi.care/skincare/fr/ingredients/aha-blend-glycolic-and-citric-acids-and-betaine)
- Work well together: [Betaine and citric acid](https://lovi.care/skincare/fr/ingredients/betaine-and-citric-acid)
- Work well together: [Glycolic acid and betaine](https://lovi.care/skincare/fr/ingredients/glycolic-acid-and-betaine)
- Work well together: [Glycerin and lactic acid](https://lovi.care/skincare/fr/ingredients/glycerin-and-lactic-acid)
- Depends on the strength: [Lactic acid and hyaluronic acid](https://lovi.care/skincare/fr/ingredients/lactic-acid-and-hyaluronic-acid)
- Work well together: [Mandelic acid and betaine](https://lovi.care/skincare/fr/ingredients/mandelic-acid-and-betaine)
- Work well together: [Betaine and tri-ceramide complex](https://lovi.care/skincare/fr/ingredients/betaine-and-tri-ceramide-complex)
- Keep them apart: [Lactic acid and acetyl hexapeptide-3](https://lovi.care/skincare/fr/ingredients/lactic-acid-and-acetyl-hexapeptide-3)
- Keep them apart: [Bio-placenta peptides and lactic acid](https://lovi.care/skincare/fr/ingredients/bio-placenta-peptides-and-lactic-acid)
- Keep them apart: [Carnosine and lactic acid](https://lovi.care/skincare/fr/ingredients/carnosine-and-lactic-acid)
- Keep them apart: [Lactic acid and collagen peptide](https://lovi.care/skincare/fr/ingredients/lactic-acid-and-collagen-peptide)
- Keep them apart: [Lactic acid and copper peptide](https://lovi.care/skincare/fr/ingredients/lactic-acid-and-copper-peptide)
- Keep them apart: [Hexapeptide and lactic acid](https://lovi.care/skincare/fr/ingredients/hexapeptide-and-lactic-acid)
- Keep them apart: [Lactic acid and hexapeptide-9](https://lovi.care/skincare/fr/ingredients/lactic-acid-and-hexapeptide-9)
- Keep them apart: [Lactic acid and palmitoyl pentapeptide-4](https://lovi.care/skincare/fr/ingredients/lactic-acid-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Lactic acid and palmitoyl tripeptide-1](https://lovi.care/skincare/fr/ingredients/lactic-acid-and-palmitoyl-tripeptide-1)
- Keep them apart: [Lactic acid and peptide-rich plasma](https://lovi.care/skincare/fr/ingredients/lactic-acid-and-peptide-rich-plasma)
- Keep them apart: [Lactic acid and triple peptide blend](https://lovi.care/skincare/fr/ingredients/lactic-acid-and-triple-peptide-blend)
- Keep them apart: [Adapalene and lactic acid](https://lovi.care/skincare/fr/ingredients/adapalene-and-lactic-acid)
- Keep them apart: [Lactic acid and granactive retinoid](https://lovi.care/skincare/fr/ingredients/lactic-acid-and-granactive-retinoid)
- Keep them apart: [Lactic acid and hydroxypinacolone retinoate](https://lovi.care/skincare/fr/ingredients/lactic-acid-and-hydroxypinacolone-retinoate)
- Keep them apart: [Pro-retinol and lactic acid](https://lovi.care/skincare/fr/ingredients/pro-retinol-and-lactic-acid)
- Keep them apart: [Retinal and lactic acid](https://lovi.care/skincare/fr/ingredients/retinal-and-lactic-acid)
- Keep them apart: [Lactic acid and retinoid blend](https://lovi.care/skincare/fr/ingredients/lactic-acid-and-retinoid-blend)
- Keep them apart: [Tretinoin and lactic acid](https://lovi.care/skincare/fr/ingredients/tretinoin-and-lactic-acid)
- Work well together: [Lactic acid and gluconolactone](https://lovi.care/skincare/fr/ingredients/lactic-acid-and-gluconolactone)
- Work well together: [Lactic acid and lactobionic acid](https://lovi.care/skincare/fr/ingredients/lactic-acid-and-lactobionic-acid)
- Work well together: [Lactic acid and cholesterol](https://lovi.care/skincare/fr/ingredients/lactic-acid-and-cholesterol)
- Work well together: [Lactic acid and lauric acid](https://lovi.care/skincare/fr/ingredients/lactic-acid-and-lauric-acid)
- Work well together: [Linoleic acid and lactic acid](https://lovi.care/skincare/fr/ingredients/linoleic-acid-and-lactic-acid)
- Keep them apart: [Lactic acid and tri-ceramide complex](https://lovi.care/skincare/fr/ingredients/lactic-acid-and-tri-ceramide-complex)
- Work well together: [Arginine and lactic acid](https://lovi.care/skincare/fr/ingredients/arginine-and-lactic-acid)
- Work well together: [Lactic acid and GABA](https://lovi.care/skincare/fr/ingredients/lactic-acid-and-gaba)
- Work well together: [Silk amino acids and lactic acid](https://lovi.care/skincare/fr/ingredients/silk-amino-acids-and-lactic-acid)
- Work well together: [Lactic acid and taurine](https://lovi.care/skincare/fr/ingredients/lactic-acid-and-taurine)
- Work well together: [Lactic acid and theanine](https://lovi.care/skincare/fr/ingredients/lactic-acid-and-theanine)
- Work well together: [Ferulic acid and lactic acid](https://lovi.care/skincare/fr/ingredients/ferulic-acid-and-lactic-acid)
- Work well together: [Vitamin E and lactic acid](https://lovi.care/skincare/fr/ingredients/vitamin-e-and-lactic-acid)
- Keep them apart: [Azelaic acid and lactic acid](https://lovi.care/skincare/fr/ingredients/azelaic-acid-and-lactic-acid)
- Keep them apart: [Salicylic acid and lactic acid](https://lovi.care/skincare/fr/ingredients/salicylic-acid-and-lactic-acid)
- Work well together: [Allantoin and lactic acid](https://lovi.care/skincare/fr/ingredients/allantoin-and-lactic-acid)
- Work well together: [Lactic acid and bisabolol](https://lovi.care/skincare/fr/ingredients/lactic-acid-and-bisabolol)
- Work well together: [Panthenol and lactic acid](https://lovi.care/skincare/fr/ingredients/panthenol-and-lactic-acid)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi checks every pairing with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this pairing advice: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/ingredients/lactic-acid-and-betaine
- United Kingdom: https://lovi.care/skincare/uk/ingredients/lactic-acid-and-betaine
- Ireland: https://lovi.care/skincare/ie/ingredients/lactic-acid-and-betaine
- Germany: https://lovi.care/skincare/de/ingredients/lactic-acid-and-betaine
- France: https://lovi.care/skincare/fr/ingredients/lactic-acid-and-betaine (this page)
- Italy: https://lovi.care/skincare/it/ingredients/lactic-acid-and-betaine
- Netherlands: https://lovi.care/skincare/nl/ingredients/lactic-acid-and-betaine
- Spain: https://lovi.care/skincare/es/ingredients/lactic-acid-and-betaine
- Canada: https://lovi.care/skincare/ca/ingredients/lactic-acid-and-betaine
- Australia: https://lovi.care/skincare/au/ingredients/lactic-acid-and-betaine
- Singapore: https://lovi.care/skincare/sg/ingredients/lactic-acid-and-betaine
- Saudi Arabia: https://lovi.care/skincare/sa/ingredients/lactic-acid-and-betaine
- United Arab Emirates: https://lovi.care/skincare/ae/ingredients/lactic-acid-and-betaine