# Sesderma vs Endocare

Page: https://lovi.care/skincare/fr/compare/sesderma-vs-endocare

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for France.

Sesderma and Endocare are Spanish skincare brands offering advanced [serums](https://lovi.care/skincare/fr/ingredients/serum), nurturing moisturizers, and sophisticated formulas. Sesderma suits sensitive, hyperpigmented, and aging skin types best through products like the Azelac RU Serum, while Endocare suits mature and dry skin best through standout choices like the Tensage Cream. Both rely on botanical [extracts](https://lovi.care/skincare/fr/ingredients/extract), active compounds, and advanced scientific formulations to refine skin texture and promote a radiant complexion. Ultimately, these brands differ in their founding years, ownership, and target skin concerns.

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

[skinexpert.sesderma.com](https://skinexpert.sesderma.com/en/jb-capital-joins-the-shareholding-of-sesderma-group-as-a-strategic-partner/) [sesderma.com](https://www.sesderma.com/us_en/about-us.html)

Endocare is a Spanish skincare brand founded in 1996 and owned by Cantabria Labs.

[pitchbook.com](https://pitchbook.com/profiles/company/267212-62) [endocare.com.tw](https://www.endocare.com.tw/)

This page compares some of the most popular Sesderma and Endocare products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg1de9fa44f4).

### Popular Sesderma vs Endocare products

#### Sesderma

- [Azelac RU Serum](https://lovi.care/skincare/fr/p/sesderma/azelac-ru-serum/for/acne-prone-skin) — High fit — [€35.90 at Amazon](https://www.amazon.fr/dp/B00987RKWW?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1)

#### Endocare

- [Tensage Cream](https://lovi.care/skincare/fr/p/endocare/tensage-cream/for/mature-skin) — Average fit

## Questions and answers

### Sesderma or Endocare: which is better?

Neither brand is universally better, as Sesderma achieves a High fit for acne-prone skin and dark spots with its Azelac RU [Serum](https://lovi.care/skincare/fr/ingredients/serum), while Endocare avoids fragrance across the products on this page and achieves an Average fit for mature skin.

### What is the difference between Sesderma and Endocare?

Sesderma offers the products on this page with fragrance, whereas every Endocare product on this page lists no fragrance. For dark spots, Sesderma Azelac RU Serum has a High Lovi fit, while Endocare Tensage Cream has an Average fit.

### Which is more affordable, Sesderma or Endocare?

I am sorry, but the provided page facts and studies do not contain pricing or affordability information for either Sesderma or Endocare.

### Which causes fewer breakouts, Sesderma or Endocare?

Endocare products on this page are unlikely to suit breakout-prone skin well, as Tensage Cream has a Low fit for acne-prone skin and Caution for oily or combination skin. Sesderma's Azelac RU Serum helps with acne-prone skin with a High fit.

[Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/)

### Which brand was founded earlier, Sesderma or Endocare?

Sesderma was founded earlier in 1989, while Endocare was founded in 1996.

### Do products from Sesderma or Endocare contain fragrance?

For the products on this page, Sesderma includes fragrance in its Azelac RU Serum, while Endocare lists no fragrance in the ingredients for any of its products.

### Which company currently owns Sesderma?

Grupo Sesderma currently owns Sesderma.

## Research behind their key ingredients

- [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007
- [Nicotinic acid/niacinamide and the skin](https://pubmed.ncbi.nlm.nih.gov/17147561/) Niacin · Journal of Cosmetic Dermatology, 2004
- [Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/27261203/) Retinol · International Journal of Cosmetic Science, 2017
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Retinol · The British Journal of Dermatology, 2019
- [Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/33923739/) Azelaic acid · Pharmaceutics, 2021
- [A topical lipophilic niacin derivative increases NAD, epidermal differentiation and barrier function in photodamaged skin](https://pubmed.ncbi.nlm.nih.gov/17518989/) Niacin · Experimental Dermatology, 2007
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [The Effects of Filtrate of the Secretion of the Cryptomphalus Aspersa on Photoaged Skin](https://pubmed.ncbi.nlm.nih.gov/23652894/) Sca · Journal of Drugs in Dermatology, 2013
- [Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Erythema and Post-Inflammatory Hyperpigmentation in Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/38734843/) Azelaic acid · Dermatology and Therapy, 2024
- [The Moisturizing Efficacy of a Proprietary Dermo-Cosmetic Product( CLS02021) Versus Placebo in a 4-week Application Period](https://pubmed.ncbi.nlm.nih.gov/35774045/) Proprietary · Medical Archives, 2022
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Efficacy and Safety of a New Cosmeceutical Regimen Based on the Combination of Snail Secretion Filtrate and Snail Egg Extract to Improve Signs of Skin Aging](https://pubmed.ncbi.nlm.nih.gov/32308795/) Sca · The Journal of Clinical and Aesthetic Dermatology, 2020
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [The efficacy of enoxolone in reducing erythema and pain after laser treatment: A randomized split-face pilot study](https://pubmed.ncbi.nlm.nih.gov/38622995/) Glycyrrhetinic acid · Journal of Cosmetic Dermatology, 2024
- [Efficacy and safety of a facial serum containing snail secretion filtrate, Calendula officinalis, and Glycyrrhiza glaba root extract in the treatment of maskne: A randomized placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/35763437/) Snail secretion filtrate sca growth factor technology filtrate · Journal of Cosmetic Dermatology, 2022
- [A novel facial moisturizer containing Saccharide isomerate accelerates skin barrier restoration following intense pulsed light treatment: a randomized split-face study](https://pubmed.ncbi.nlm.nih.gov/41211697/) Saccharide isomerate · The Journal of Dermatological Treatment, 2025

## The brands

- Spanish skincare: [Sesderma](https://lovi.care/skincare/fr/brands/sesderma)
- Spanish skincare: [Endocare](https://lovi.care/skincare/fr/brands/endocare)

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- [La Roche-Posay vs Endocare](https://lovi.care/skincare/fr/compare/la-roche-posay-vs-endocare)
- [Dr. Althea vs Sesderma](https://lovi.care/skincare/fr/compare/dr-althea-vs-sesderma)
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- [Some By Mi vs Sesderma](https://lovi.care/skincare/fr/compare/some-by-mi-vs-sesderma)
- [Some By Mi vs Endocare](https://lovi.care/skincare/fr/compare/some-by-mi-vs-endocare)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/sesderma-vs-endocare
- United Kingdom: https://lovi.care/skincare/uk/compare/sesderma-vs-endocare
- Ireland: https://lovi.care/skincare/ie/compare/sesderma-vs-endocare
- Germany: https://lovi.care/skincare/de/compare/sesderma-vs-endocare
- France: https://lovi.care/skincare/fr/compare/sesderma-vs-endocare (this page)
- Italy: https://lovi.care/skincare/it/compare/sesderma-vs-endocare
- Netherlands: https://lovi.care/skincare/nl/compare/sesderma-vs-endocare
- Spain: https://lovi.care/skincare/es/compare/sesderma-vs-endocare
- Canada: https://lovi.care/skincare/ca/compare/sesderma-vs-endocare
- Australia: https://lovi.care/skincare/au/compare/sesderma-vs-endocare
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