# Sesderma vs Ambi Skincare Page: https://lovi.care/skincare/fr/compare/sesderma-vs-ambi-skincare The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for France. Sesderma and Ambi Skincare are respected skincare lines offering advanced [serums](https://lovi.care/skincare/fr/ingredients/serum) and targeted formulas. Founded in 1989 and owned by Grupo Sesderma since 2026, the Spanish brand is known for its meticulously engineered formulas with botanical [extracts](https://lovi.care/skincare/fr/ingredients/extract) and active compounds that suit sensitive, hyperpigmented, and aging skin types, including the Azelac RU Serum for acne-prone skin. Meanwhile, the other brand is warmly loved for its gentle care addressing melanin-rich skin, featuring the Fade Cream as a standout product for acne-prone skin. While both help maintain a balanced and radiant complexion through consistent use, they differ in their specific formulations and ideal skin types. Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026. [skinexpert.sesderma.com](https://skinexpert.sesderma.com/en/jb-capital-joins-the-shareholding-of-sesderma-group-as-a-strategic-partner/) [sesderma.com](https://www.sesderma.com/us_en/about-us.html) This page compares some of the most popular Sesderma and Ambi Skincare products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg38fe8f1d12). ### Popular Sesderma vs Ambi Skincare products #### Ambi Skincare - [Fade Cream](https://lovi.care/skincare/fr/p/ambi-skincare/fade-cream/for/dark-spots) — High fit — [€28.36 at Amazon](https://www.amazon.fr/dp/B0BTQ79WBC?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1) #### Sesderma - [Azelac RU Serum](https://lovi.care/skincare/fr/p/sesderma/azelac-ru-serum/for/acne-prone-skin) — High fit — [€35.90 at Amazon](https://www.amazon.fr/dp/B00987RKWW?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1) ### Sesderma vs Ambi Skincare [serums](https://lovi.care/skincare/fr/ingredients/serum) and treatments #### Ambi Skincare - [Fade Cream](https://lovi.care/skincare/fr/p/ambi-skincare/fade-cream/for/dark-spots) — High fit — [€28.36 at Amazon](https://www.amazon.fr/dp/B0BTQ79WBC?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1) #### Sesderma - [Azelac RU Serum](https://lovi.care/skincare/fr/p/sesderma/azelac-ru-serum/for/acne-prone-skin) — High fit — [€35.90 at Amazon](https://www.amazon.fr/dp/B00987RKWW?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1) ## Questions and answers ### Sesderma or Ambi Skincare: which is better? For skin with dark spots, Ambi Skincare's Fade Cream and Sesderma's Azelac RU [Serum](https://lovi.care/skincare/fr/ingredients/serum) both earn a High Lovi fit level, making them both strong choices depending on your fragrance preference. Ambi Skincare products on this page list no fragrance, while Sesderma includes fragrance in its serum. ### What is the difference between Sesderma and Ambi Skincare? For skin with dark spots, both Sesderma and Ambi Skincare achieve a High Lovi fit level across the products on this page. Sesderma's Azelac RU Serum contains fragrance, whereas Ambi Skincare's Fade Cream lists no fragrance in its ingredients. ### Which is more affordable, Sesderma or Ambi Skincare? Neither brand lists prices or affordability details for the products on this page, so a comparison cannot be made. ### Which causes fewer breakouts, Sesderma or Ambi Skincare? For acne-prone skin, Lovi rates Sesderma's Azelac RU Serum as High and Ambi Skincare's Fade Cream as Average. Sesderma contains fragrance, whereas Ambi Skincare lists no fragrance. ### When were Sesderma and Ambi Skincare founded and who currently owns them? Sesderma was founded in Spain in 1989 and is owned by Grupo Sesderma since 2026. Ambi Skincare was founded in 1966 and is owned by AMBI Enterprises LLC since 2018. ### Which products from Sesderma and Ambi Skincare contain fragrance? Sesderma includes Azelac RU Serum, which lists fragrance among its ingredients. In contrast, Ambi Skincare features products on this page that all list no fragrance. ### How does the Lovi fit level for oily skin compare between Azelac RU Serum and Fade Cream? Fade Cream has a High Lovi fit level for oily skin, whereas Azelac RU Serum has an Average Lovi fit level for oily skin. Both products on this page are serums designed to address dark spots. ## Research behind their key ingredients - [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000 - [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002 - [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007 - [Nicotinic acid/niacinamide and the skin](https://pubmed.ncbi.nlm.nih.gov/17147561/) Niacin · Journal of Cosmetic Dermatology, 2004 - [Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/27261203/) Retinol · International Journal of Cosmetic Science, 2017 - [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Retinol · The British Journal of Dermatology, 2019 - [Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/33923739/) Azelaic acid · Pharmaceutics, 2021 - [A topical lipophilic niacin derivative increases NAD, epidermal differentiation and barrier function in photodamaged skin](https://pubmed.ncbi.nlm.nih.gov/17518989/) Niacin · Experimental Dermatology, 2007 - [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017 - [Comparison of clinical efficacies of sodium ascorbyl phosphate, retinol and their combination in acne treatment](https://pubmed.ncbi.nlm.nih.gov/19134126/) Sodium ascorbyl phosphate · International Journal of Cosmetic Science, 2009 - [Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Erythema and Post-Inflammatory Hyperpigmentation in Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/38734843/) Azelaic acid · Dermatology and Therapy, 2024 - [Efficacy of a topical serum containing L-ascorbic acid, neohesperidin, pycnogenol, tocopherol, and hyaluronic acid in relation to skin aging signs](https://pubmed.ncbi.nlm.nih.gov/35150043/) Vitamin e · Journal of Cosmetic Dermatology, 2022 - [Assessment of Combined Ascorbyl Palmitate (AP) and Sodium Ascorbyl Phosphate (SAP) on Facial Skin Sebum Control in Female Healthy Volunteers](https://pubmed.ncbi.nlm.nih.gov/27756097/) Sodium ascorbyl phosphate · Drug Research, 2017 - [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998 - [Modulation of skin pigmentation by the tetrapeptide PKEK: in vitro and in vivo evidence for skin whitening effects](https://pubmed.ncbi.nlm.nih.gov/22142309/) Sodium ascorbyl phosphate · Experimental Dermatology, 2012 - [Tocopherol succinate-loaded ethosomal gel synthesized by cold method technique: Deeper biophysical characterizations for translational application on human skin](https://pubmed.ncbi.nlm.nih.gov/38268219/) Vitamin e · Journal of Cosmetic Dermatology, 2024 - [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025 - [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021 - [The efficacy of enoxolone in reducing erythema and pain after laser treatment: A randomized split-face pilot study](https://pubmed.ncbi.nlm.nih.gov/38622995/) Glycyrrhetinic acid · Journal of Cosmetic Dermatology, 2024 - [Facial disbiosis and UV filters](https://pubmed.ncbi.nlm.nih.gov/39499337/) Octinoxate · Archives of Dermatological Research, 2024 ## The brands - Spanish skincare: [Sesderma](https://lovi.care/skincare/fr/brands/sesderma) - Skincare: [Ambi Skincare](https://lovi.care/skincare/fr/brands/ambi-skincare) ## More comparisons - [SKIN1004 vs Sesderma](https://lovi.care/skincare/fr/compare/skin1004-vs-sesderma) - [SKIN1004 vs Ambi Skincare](https://lovi.care/skincare/fr/compare/skin1004-vs-ambi-skincare) - [Anua vs Sesderma](https://lovi.care/skincare/fr/compare/anua-vs-sesderma) - [Anua vs Ambi Skincare](https://lovi.care/skincare/fr/compare/anua-vs-ambi-skincare) - [Medicube vs Sesderma](https://lovi.care/skincare/fr/compare/medicube-vs-sesderma) - [Medicube vs Ambi Skincare](https://lovi.care/skincare/fr/compare/medicube-vs-ambi-skincare) - [The Ordinary vs Sesderma](https://lovi.care/skincare/fr/compare/the-ordinary-vs-sesderma) - [The Ordinary vs Ambi Skincare](https://lovi.care/skincare/fr/compare/the-ordinary-vs-ambi-skincare) - [Beauty of Joseon vs Sesderma](https://lovi.care/skincare/fr/compare/beauty-of-joseon-vs-sesderma) - [Beauty of Joseon vs Ambi Skincare](https://lovi.care/skincare/fr/compare/beauty-of-joseon-vs-ambi-skincare) - [COSRX vs Sesderma](https://lovi.care/skincare/fr/compare/cosrx-vs-sesderma) - [COSRX vs Ambi Skincare](https://lovi.care/skincare/fr/compare/cosrx-vs-ambi-skincare) - [CeraVe vs Sesderma](https://lovi.care/skincare/fr/compare/cerave-vs-sesderma) - [CeraVe vs Ambi Skincare](https://lovi.care/skincare/fr/compare/cerave-vs-ambi-skincare) - [La Roche-Posay vs Sesderma](https://lovi.care/skincare/fr/compare/la-roche-posay-vs-sesderma) - [La Roche-Posay vs Ambi Skincare](https://lovi.care/skincare/fr/compare/la-roche-posay-vs-ambi-skincare) - [Dr. Althea vs Sesderma](https://lovi.care/skincare/fr/compare/dr-althea-vs-sesderma) - [Dr. Althea vs Ambi Skincare](https://lovi.care/skincare/fr/compare/dr-althea-vs-ambi-skincare) - [Some By Mi vs Sesderma](https://lovi.care/skincare/fr/compare/some-by-mi-vs-sesderma) - [Some By Mi vs Ambi Skincare](https://lovi.care/skincare/fr/compare/some-by-mi-vs-ambi-skincare) ## About the Lovi Fit Lovi: Unbiased, science-based skincare AI trained on real user outcomes. Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning. Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board). Page built Nov 8, 2026. More from Lovi: https://lovi.care/skincare/llms.txt ## This page in other countries - United States: https://lovi.care/skincare/compare/sesderma-vs-ambi-skincare - United Kingdom: https://lovi.care/skincare/uk/compare/sesderma-vs-ambi-skincare - Ireland: https://lovi.care/skincare/ie/compare/sesderma-vs-ambi-skincare - Germany: https://lovi.care/skincare/de/compare/sesderma-vs-ambi-skincare - France: https://lovi.care/skincare/fr/compare/sesderma-vs-ambi-skincare (this page) - Italy: https://lovi.care/skincare/it/compare/sesderma-vs-ambi-skincare - Netherlands: https://lovi.care/skincare/nl/compare/sesderma-vs-ambi-skincare - Spain: https://lovi.care/skincare/es/compare/sesderma-vs-ambi-skincare - Canada: https://lovi.care/skincare/ca/compare/sesderma-vs-ambi-skincare - Australia: https://lovi.care/skincare/au/compare/sesderma-vs-ambi-skincare - Singapore: https://lovi.care/skincare/sg/compare/sesderma-vs-ambi-skincare - Saudi Arabia: https://lovi.care/skincare/sa/compare/sesderma-vs-ambi-skincare - United Arab Emirates: https://lovi.care/skincare/ae/compare/sesderma-vs-ambi-skincare