# Mesoestetic vs SKIN&CO Page: https://lovi.care/skincare/fr/compare/mesoestetic-vs-skin-and-co The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for France. Mesoestetic and SKIN&CO are celebrated skincare brands offering expertly crafted formulas designed to elevate daily routines. The Spanish house, founded in 1984 and owned by Mesoestetic Pharma Group, S.L., is known for targeted [serums](https://lovi.care/skincare/fr/ingredients/serum) that suit mature, sensitive, and uneven skin, featuring the Cosmelan 2 for precise acne care. Meanwhile, the second brand is loved for deeply nourishing moisturizers suited to dry, normal, and combination skin, offering the Truffle Therapy Serum for acne-prone complexions. Both deliver balanced nourishment and thoughtful care, differing primarily in their specific targeted ingredients and the ideal skin types they serve. Mesoestetic is a Spanish skincare brand founded in 1984 and owned by Mesoestetic Pharma Group, S.L.. [mesoestetic.com](https://www.mesoestetic.com/about-us) [tracxn.com](https://tracxn.com/d/companies/mesoestetic/__1eAnF7uALQzHII_So8HqZbHfSUJuilusj9hTisrG0tk) This page compares some of the most popular Mesoestetic and SKIN&CO products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg641e5c66af). ### Popular Mesoestetic vs SKIN&CO products #### Mesoestetic - [Cosmelan 2](https://lovi.care/skincare/fr/p/mesoestetic/cosmelan-2/for/acne-prone-skin) — Average fit #### SKIN&CO - [Truffle Therapy Serum](https://lovi.care/skincare/fr/p/skin-and-co/truffle-therapy-serum/for/dry-skin) — Average fit ## Questions and answers ### Mesoestetic or SKIN&CO: which is better? Neither brand is universally better, as Lovi rates all the products on this page as having an Average fit for most skin types. Mesoestetic has no fragrance in its products on this page, whereas SKIN&CO includes fragrance in its Truffle Therapy [Serum](https://lovi.care/skincare/fr/ingredients/serum). ### What is the difference between Mesoestetic and SKIN&CO? Mesoestetic is a Spanish brand founded in 1984, while SKIN&CO is an independent brand founded in 2008. Furthermore, every product on this page from Mesoestetic lists no fragrance, whereas the Truffle Therapy Serum from SKIN&CO includes fragrance. ### Which is more affordable, Mesoestetic or SKIN&CO? The provided page facts do not contain pricing information, so it is not possible to determine whether Mesoestetic or SKIN&CO is more affordable. ### Which causes fewer breakouts, Mesoestetic or SKIN&CO? For acne-prone skin, Mesoestetic and SKIN&CO both have an average Lovi fit, meaning the products on this page help similarly with breakouts. Every product by Mesoestetic on this page lists no fragrance, whereas SKIN&CO includes fragrance. ### Which brand uses fragrance in its products, Mesoestetic or SKIN&CO? SKIN&CO uses fragrance in its Truffle Therapy Serum, whereas every product from Mesoestetic lists no fragrance. ### When were Mesoestetic and SKIN&CO founded? Mesoestetic was founded in 1984 in Spain, while SKIN&CO was founded in 2008. ### What is the Lovi fit level of Cosmelan 2 for sensitive skin? For sensitive skin, the Lovi fit level of Cosmelan 2 is Low. ## Research behind their key ingredients - [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002 - [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice · Clinical Pharmacology, 2018 - [Tailoring of Retinyl Palmitate-Based Ethosomal Hydrogel as a Novel Nanoplatform for Acne Vulgaris Management: Fabrication, Optimization, and Clinical Evaluation Employing a Split-Face Comparative Study](https://pubmed.ncbi.nlm.nih.gov/34211271/) Retinyl palmitate · International Journal of Nanomedicine, 2021 - [Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/33923739/) Azelaic acid · Pharmaceutics, 2021 - [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017 - [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020 - [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024 - [Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Erythema and Post-Inflammatory Hyperpigmentation in Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/38734843/) Azelaic acid · Dermatology and Therapy, 2024 - [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023 ## The brands - Spanish skincare: [Mesoestetic](https://lovi.care/skincare/fr/brands/mesoestetic) - Skincare: [SKIN&CO](https://lovi.care/skincare/fr/brands/skin-and-co) ## More comparisons - [SKIN1004 vs Mesoestetic](https://lovi.care/skincare/fr/compare/skin1004-vs-mesoestetic) - [SKIN1004 vs SKIN&CO](https://lovi.care/skincare/fr/compare/skin1004-vs-skin-and-co) - [Anua vs Mesoestetic](https://lovi.care/skincare/fr/compare/anua-vs-mesoestetic) - [Anua vs SKIN&CO](https://lovi.care/skincare/fr/compare/anua-vs-skin-and-co) - [Medicube vs Mesoestetic](https://lovi.care/skincare/fr/compare/medicube-vs-mesoestetic) - [Medicube vs SKIN&CO](https://lovi.care/skincare/fr/compare/medicube-vs-skin-and-co) - [The Ordinary vs Mesoestetic](https://lovi.care/skincare/fr/compare/the-ordinary-vs-mesoestetic) - [The Ordinary vs SKIN&CO](https://lovi.care/skincare/fr/compare/the-ordinary-vs-skin-and-co) - [Beauty of Joseon vs Mesoestetic](https://lovi.care/skincare/fr/compare/beauty-of-joseon-vs-mesoestetic) - [Beauty of Joseon vs SKIN&CO](https://lovi.care/skincare/fr/compare/beauty-of-joseon-vs-skin-and-co) - [COSRX vs Mesoestetic](https://lovi.care/skincare/fr/compare/cosrx-vs-mesoestetic) - [COSRX vs SKIN&CO](https://lovi.care/skincare/fr/compare/cosrx-vs-skin-and-co) - [CeraVe vs Mesoestetic](https://lovi.care/skincare/fr/compare/cerave-vs-mesoestetic) - [CeraVe vs SKIN&CO](https://lovi.care/skincare/fr/compare/cerave-vs-skin-and-co) - [La Roche-Posay vs Mesoestetic](https://lovi.care/skincare/fr/compare/la-roche-posay-vs-mesoestetic) - [La Roche-Posay vs SKIN&CO](https://lovi.care/skincare/fr/compare/la-roche-posay-vs-skin-and-co) - [Dr. Althea vs Mesoestetic](https://lovi.care/skincare/fr/compare/dr-althea-vs-mesoestetic) - [Dr. Althea vs SKIN&CO](https://lovi.care/skincare/fr/compare/dr-althea-vs-skin-and-co) - [Some By Mi vs Mesoestetic](https://lovi.care/skincare/fr/compare/some-by-mi-vs-mesoestetic) - [Some By Mi vs SKIN&CO](https://lovi.care/skincare/fr/compare/some-by-mi-vs-skin-and-co) ## About the Lovi Fit Lovi: Unbiased, science-based skincare AI trained on real user outcomes. Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning. Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board). Page built Nov 8, 2026. More from Lovi: https://lovi.care/skincare/llms.txt ## This page in other countries - United States: https://lovi.care/skincare/compare/mesoestetic-vs-skin-and-co - United Kingdom: https://lovi.care/skincare/uk/compare/mesoestetic-vs-skin-and-co - Ireland: https://lovi.care/skincare/ie/compare/mesoestetic-vs-skin-and-co - Germany: https://lovi.care/skincare/de/compare/mesoestetic-vs-skin-and-co - France: https://lovi.care/skincare/fr/compare/mesoestetic-vs-skin-and-co (this page) - Italy: https://lovi.care/skincare/it/compare/mesoestetic-vs-skin-and-co - Netherlands: https://lovi.care/skincare/nl/compare/mesoestetic-vs-skin-and-co - Spain: https://lovi.care/skincare/es/compare/mesoestetic-vs-skin-and-co - Canada: https://lovi.care/skincare/ca/compare/mesoestetic-vs-skin-and-co - Australia: https://lovi.care/skincare/au/compare/mesoestetic-vs-skin-and-co - Singapore: https://lovi.care/skincare/sg/compare/mesoestetic-vs-skin-and-co - Saudi Arabia: https://lovi.care/skincare/sa/compare/mesoestetic-vs-skin-and-co - United Arab Emirates: https://lovi.care/skincare/ae/compare/mesoestetic-vs-skin-and-co