# Mesoestetic vs grace & stella

Page: https://lovi.care/skincare/fr/compare/mesoestetic-vs-grace-and-stella

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for France.

Mesoestetic and grace & stella are two distinctive skincare lines offering thoughtful solutions for daily routines. The Spanish brand is known for targeted [serums](https://lovi.care/skincare/fr/ingredients/serum) with meticulous formulas that suit mature, sensitive, and uneven skin best, featuring the Cosmelan 2 for acne-prone skin. Meanwhile, the Canadian brand is loved for nourishing eye products and moisturizers that suit all skin types, including Under Eye Masks for acne-prone skin and [Hyaluronic Acid](https://lovi.care/skincare/fr/ingredients/hyaluronic-acid) Serum for dark spots. While both deliver balanced nourishment and long-term health, they differ through the former's rigorous composition for specific sensitivities and the latter's versatile hydration for universal self-care.

Mesoestetic is a Spanish skincare brand founded in 1984 and owned by Mesoestetic Pharma Group, S.L..

[mesoestetic.com](https://www.mesoestetic.com/about-us) [tracxn.com](https://tracxn.com/d/companies/mesoestetic/__1eAnF7uALQzHII_So8HqZbHfSUJuilusj9hTisrG0tk)

grace & stella is a Canadian skincare brand founded in 2016 and owned by Gravitiq since 2022.

[graceandstella.com](https://www.graceandstella.com/pages/faq) [tracxn.com](https://tracxn.com/d/companies/gravitiq/__cAcLAYVXizPoeM7P-lpcSTukNbDz1463zb8cbxeIerY) [pitchbook.com](https://pitchbook.com/profiles/company/484071-94) [preqin.com](https://www.preqin.com/data/profile/asset/gravitiq-holdings--inc-/454659)

This page compares some of the most popular Mesoestetic and grace & stella products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pgeaaf53e375).

### Popular Mesoestetic vs grace & stella products

#### grace & stella

- [Under Eye Mask](https://lovi.care/skincare/fr/p/grace-and-stella/under-eye-mask/for/oily-skin) — Superior fit — [€27.95 at Amazon](https://www.amazon.fr/dp/B014G1G10Q?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1)
- [Hyaluronic Acid Serum](https://lovi.care/skincare/fr/p/grace-and-stella/hyaluronic-acid-serum/for/dry-sensitive-skin) — High fit

#### Mesoestetic

- [Cosmelan 2](https://lovi.care/skincare/fr/p/mesoestetic/cosmelan-2/for/acne-prone-skin) — Average fit

## Questions and answers

### Mesoestetic or grace & stella: which is better?

grace & stella is generally the better choice here, offering Superior to High Lovi fit levels across most skin types for products like their Under Eye Mask and [Hyaluronic Acid](https://lovi.care/skincare/fr/ingredients/hyaluronic-acid) [Serum](https://lovi.care/skincare/fr/ingredients/serum). By comparison, Mesoestetic shows only Average fits for its Cosmelan 2 serum across similar skin types, along with Low fits for sensitive and dry skin. All the products on this page for both brands list no fragrance in their ingredients.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### What is the difference between Mesoestetic and grace & stella?

grace & stella has a Superior fit for oily skin with its Under Eye Mask and High fits across most skin types, whereas Mesoestetic has Average fits for its Cosmelan 2 serum and Low fits for sensitive or dry skin. Every product on this page for both brands lists no fragrance in its ingredients.

### Which is more affordable, Mesoestetic or grace & stella?

Neither grace & stella nor Mesoestetic shares pricing information on this page, so a comparison of which brand is more affordable cannot be made.

### Which causes fewer breakouts, Mesoestetic or grace & stella?

grace & stella fits acne-prone skin with a High Lovi level on this page, while Mesoestetic products on this page show an Average fit for it. Every product on this page for both brands lists no fragrance in its ingredients.

### Where are Mesoestetic and grace & stella headquartered?

Mesoestetic is headquartered in Spain and grace & stella is headquartered in Canada.

### How does the Lovi fit level for dry skin compare between Mesoestetic's Cosmelan 2 and grace & stella's Hyaluronic Acid Serum?

Mesoestetic's Cosmelan 2 has a Low Lovi fit level for dry skin, whereas grace & stella's Hyaluronic Acid Serum reaches a High fit level.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Do any of the products from Mesoestetic or grace & stella contain fragrance?

Every product on this page from both Mesoestetic and grace & stella lists no fragrance in its ingredients.

## Research behind their key ingredients

- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice · Clinical Pharmacology, 2018
- [Tailoring of Retinyl Palmitate-Based Ethosomal Hydrogel as a Novel Nanoplatform for Acne Vulgaris Management: Fabrication, Optimization, and Clinical Evaluation Employing a Split-Face Comparative Study](https://pubmed.ncbi.nlm.nih.gov/34211271/) Retinyl palmitate · International Journal of Nanomedicine, 2021
- [Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/33923739/) Azelaic acid · Pharmaceutics, 2021
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Erythema and Post-Inflammatory Hyperpigmentation in Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/38734843/) Azelaic acid · Dermatology and Therapy, 2024
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025
- [Functional properties and skin care effects of sodium trehalose sulfate](https://pubmed.ncbi.nlm.nih.gov/38606717/) Trehalose · Skin Research and Technology, 2024

## The brands

- Spanish skincare: [Mesoestetic](https://lovi.care/skincare/fr/brands/mesoestetic)
- Canadian skincare: [grace & stella](https://lovi.care/skincare/fr/brands/grace-and-stella)

## More comparisons

- [SKIN1004 vs Mesoestetic](https://lovi.care/skincare/fr/compare/skin1004-vs-mesoestetic)
- [SKIN1004 vs grace & stella](https://lovi.care/skincare/fr/compare/skin1004-vs-grace-and-stella)
- [Anua vs Mesoestetic](https://lovi.care/skincare/fr/compare/anua-vs-mesoestetic)
- [Anua vs grace & stella](https://lovi.care/skincare/fr/compare/anua-vs-grace-and-stella)
- [Medicube vs Mesoestetic](https://lovi.care/skincare/fr/compare/medicube-vs-mesoestetic)
- [Medicube vs grace & stella](https://lovi.care/skincare/fr/compare/medicube-vs-grace-and-stella)
- [The Ordinary vs Mesoestetic](https://lovi.care/skincare/fr/compare/the-ordinary-vs-mesoestetic)
- [The Ordinary vs grace & stella](https://lovi.care/skincare/fr/compare/the-ordinary-vs-grace-and-stella)
- [Beauty of Joseon vs Mesoestetic](https://lovi.care/skincare/fr/compare/beauty-of-joseon-vs-mesoestetic)
- [Beauty of Joseon vs grace & stella](https://lovi.care/skincare/fr/compare/beauty-of-joseon-vs-grace-and-stella)
- [COSRX vs Mesoestetic](https://lovi.care/skincare/fr/compare/cosrx-vs-mesoestetic)
- [COSRX vs grace & stella](https://lovi.care/skincare/fr/compare/cosrx-vs-grace-and-stella)
- [CeraVe vs Mesoestetic](https://lovi.care/skincare/fr/compare/cerave-vs-mesoestetic)
- [CeraVe vs grace & stella](https://lovi.care/skincare/fr/compare/cerave-vs-grace-and-stella)
- [La Roche-Posay vs Mesoestetic](https://lovi.care/skincare/fr/compare/la-roche-posay-vs-mesoestetic)
- [La Roche-Posay vs grace & stella](https://lovi.care/skincare/fr/compare/la-roche-posay-vs-grace-and-stella)
- [Dr. Althea vs Mesoestetic](https://lovi.care/skincare/fr/compare/dr-althea-vs-mesoestetic)
- [Dr. Althea vs grace & stella](https://lovi.care/skincare/fr/compare/dr-althea-vs-grace-and-stella)
- [Some By Mi vs Mesoestetic](https://lovi.care/skincare/fr/compare/some-by-mi-vs-mesoestetic)
- [Some By Mi vs grace & stella](https://lovi.care/skincare/fr/compare/some-by-mi-vs-grace-and-stella)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

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- France: https://lovi.care/skincare/fr/compare/mesoestetic-vs-grace-and-stella (this page)
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- Spain: https://lovi.care/skincare/es/compare/mesoestetic-vs-grace-and-stella
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