# La Roche-Posay vs Grown Alchemist

Page: https://lovi.care/skincare/fr/compare/la-roche-posay-vs-grown-alchemist

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for France.

La Roche-Posay and Grown Alchemist are two distinct skincare lines known for thoughtful formulations that address a variety of [complex](https://lovi.care/skincare/fr/ingredients/complex) skin types. The French brand, established in 1975 and under L'Oréal S.A. ownership since 1989, features nourishing [serums](https://lovi.care/skincare/fr/ingredients/serum), rich moisturizers, gentle cleansers, and targeted eye products powered by [glycerin](https://lovi.care/skincare/fr/ingredients/glycerin), soothing [thermal water](https://lovi.care/skincare/fr/ingredients/thermal-water), and [niacinamide](https://lovi.care/skincare/fr/ingredients/niacinamide) to best suit mature skin and skin with dark spots. Conversely, the second line is recognized for its own dedicated cleansers, serums, and overall formulas designed to ideally accommodate sensitive, dry, and combination skin. While both offer standout solutions for acne-prone skin, dark spots, and mature concerns, they fundamentally differ in their ingredient philosophies and targeted skin compatibility.

La Roche-Posay is a French skincare brand founded in 1975 and owned by L'Oréal S.A. since 1989.

[laroche-posay.com.au](https://www.laroche-posay.com.au/our-commitments/history.html) [fr.wikipedia.org](https://fr.wikipedia.org/wiki/L%27Or%C3%A9al)

This page compares some of the most popular La Roche-Posay and Grown Alchemist products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pgf0cdc37e30).

### Popular La Roche-Posay vs Grown Alchemist products

#### La Roche-Posay

- [Toleriane Double Repair Face Moisturizer](https://lovi.care/skincare/fr/p/la-roche-posay/toleriane-double-repair-face-moisturizer/for/oily-acne-prone-skin) — High fit
- [Cicaplast Baume B5+](https://lovi.care/skincare/fr/p/la-roche-posay/cicaplast-baume-b5/for/sensitive-skin) — Superior fit — [€17.78 at Amazon](https://www.amazon.fr/dp/B07SNCRCP1?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1)
- [Mela B3 Serum](https://lovi.care/skincare/fr/p/la-roche-posay/mela-b3-serum/for/acne-prone-skin) — High fit — [€55.61 at Amazon](https://www.amazon.fr/dp/B0BQF5X6FR?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1)
- [Retinol B3 Serum](https://lovi.care/skincare/fr/p/la-roche-posay/retinol-b3-serum/for/dark-spots) — Average fit — [€44.16 at Lookfantastic](https://www.lookfantastic.fr/p/la-roche-posay-retinol-b3-anti-wrinkle-anti-ageing-serum-with-retinol-and-vitamin-b3-suitable-for-sensitive-skin-30ml/12382710/)
- [Effaclar Medicated Gel Cleanser](https://lovi.care/skincare/fr/p/la-roche-posay/effaclar-medicated-gel-cleanser/for/acne-prone-skin) — High fit — [€16.90 at Notino](https://www.notino.fr/la-roche-posay/effaclar-gel-purifiant-en-profondeur-pour-peaux-grasses-sensibles/p-75718/)
- [Hyalu B5 Serum](https://lovi.care/skincare/fr/p/la-roche-posay/hyalu-b5-serum/for/sensitive-skin) — High fit — [€40.00 at Amazon](https://www.amazon.fr/dp/B0CZ3WBPTJ?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1)
- [Lipikar AP+M Triple Repair Moisturizing Cream](https://lovi.care/skincare/fr/p/la-roche-posay/lipikar-ap-m-triple-repair-moisturizing-cream/for/dry-skin) — High fit — [€25.42 at Amazon](https://www.amazon.fr/dp/B0849KTG44?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1)
- [Anthelios](https://lovi.care/skincare/fr/p/la-roche-posay/anthelios/for/dark-spots) — Superior fit — [€26.00 at Amazon](https://www.amazon.fr/dp/B0GZK2X1H4?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1)

#### Grown Alchemist

- [Gentle Gel Facial Cleanser](https://lovi.care/skincare/fr/p/grown-alchemist/gentle-gel-facial-cleanser/for/dry-sensitive-skin) — Average fit
- [Hydra-Restore Cream Cleanser](https://lovi.care/skincare/fr/p/grown-alchemist/hydra-restore-cream-cleanser/for/sensitive-skin) — High fit — [€35.00 at Amazon](https://www.amazon.fr/dp/B00G3J8ISI?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1)
- [Instant Smoothing Serum](https://lovi.care/skincare/fr/p/grown-alchemist/instant-smoothing-serum/for/dry-sensitive-skin) — Average fit

## People Say

La Roche-Posay

Grown Alchemist

- Skin Soothing and Sensitivity Mostly Mentioned Mostly Mentioned “Great retinol for beginners — La Roche-Posay Retinol B3 Serum” “Only cream that doesn't sting — La Roche-Posay Toleriane Dermallergo Eye Cream” “Calmed my skin after a chemical peel — La Roche-Posay Thermal Spring Water” “Perfect for sensitive skin — Grown Alchemist Gentle Gel Facial Cleanser”
- Hydration and Moisture Mostly Mentioned Mostly Mentioned “absorbs instantly — La Roche-Posay Toleriane Double Repair Face Moisturizer” “skin feels plump — La Roche-Posay Hyalu B5 Serum” “Skin version of chugging water — Grown Alchemist Instant Smoothing Serum” “doesn't strip at all — Grown Alchemist Hydra-Restore Cream Cleanser”
- Skin Texture Improvement Mostly Mentioned Often Mentioned “lightweight and absorbs quickly — La Roche-Posay Mela B3 Serum” “absorbs in seconds — La Roche-Posay Anthelios” “silkiest cleanser — Grown Alchemist Hydra-Restore Cream Cleanser” “Smooths out fine lines — Grown Alchemist Instant Smoothing Serum”
- Fragrance and Scent (Positive) Not noted Mostly Mentioned “Smells amazing — Grown Alchemist Gentle Gel Facial Cleanser” “smell is divine — Grown Alchemist Hydra-Restore Cream Cleanser”
- Price and Value Sometimes Noted Often Mentioned “expensive for the size — La Roche-Posay Hyalu B5 Serum” “Too expensive for the size — La Roche-Posay Toleriane Dermallergo Eye Cream” “Tube is tiny for the price — La Roche-Posay Cicaplast Gel B5” “expensive for what it is — Grown Alchemist Hydra-Restore Cream Cleanser”
- Packaging and Pump Issues Often Mentioned Often Mentioned “pump stops working — La Roche-Posay Lipikar AP+M Triple Repair Moisturizing Cream” “Pump stopped working halfway — La Roche-Posay Toleriane Dermallergo Eye Cream” “tube cracks easily — Grown Alchemist Hydra-Restore Cream Cleanser” “Metal tube gets annoying — Grown Alchemist Gentle Gel Facial Cleanser”
- Fragrance and Scent Sometimes Noted Often Mentioned “scent is awful — La Roche-Posay Mela B3 Serum” “overwhelming floral smell — La Roche-Posay Hyalu B5 Serum” “Too perfumy notes — Grown Alchemist Gentle Gel Facial Cleanser” “smells medicinal — Grown Alchemist Hydra-Restore Cream Cleanser”
- Makeup Incompatibility Rarely Noted Often Mentioned “Pills under makeup — La Roche-Posay Cicaplast Baume B5+” “Pills under my foundation — La Roche-Posay Cicaplast Gel B5” “Isn't going to be your makeup remover — Grown Alchemist Gentle Gel Facial Cleanser”

## Questions and answers

### La Roche-Posay or Grown Alchemist: which is better?

La Roche-Posay fits mature skin, skin with dark spots, and dry skin best, and reviewers frequently mention its gentle and effective [serums](https://lovi.care/skincare/fr/ingredients/serum) and soothing moisturizers. Grown Alchemist features fragrance-free formulas and hydrating cleansers, though reviewers note performance and packaging issues.

### What is the difference between La Roche-Posay and Grown Alchemist?

La Roche-Posay offers a much wider selection of products on this page compared to Grown Alchemist, and it fits best for mature skin, skin with dark spots, and dry skin.

### La Roche-Posay or Grown Alchemist: which cleanser is better?

La Roche-Posay offers more cleanser options on this page that achieve High Lovi fit levels for specific skin types, such as the Effaclar Medicated Gel Cleanser for acne-prone and oily skin.

### Which is more affordable, La Roche-Posay or Grown Alchemist?

Grown Alchemist is more affordable according to reviewer feedback, as price, value, and size concerns are often mentioned for La Roche-Posay products on this page.

### Which causes fewer breakouts, La Roche-Posay or Grown Alchemist?

La Roche-Posay helps address acne-prone and oily acne-prone skin with targeted options like Effaclar [Adapalene](https://lovi.care/skincare/fr/ingredients/adapalene) Gel, which Lovi rates as Superior for acne-prone skin. Grown Alchemist features fewer products on this page, and its cleansers and serums achieve Average Lovi fit levels for acne-prone skin.

### How do the founding years and current ownership of La Roche-Posay and Grown Alchemist compare?

La Roche-Posay was founded in France in 1975 and has been owned by L'Oréal S.A. since 1989, whereas Grown Alchemist was founded in 2008 and has been independently owned since 2024.

### Which brand has more fragrance-free options among their listed products?

La Roche-Posay has more fragrance-free options among the products on this page, with 21 out of 35 items listing no fragrance.

### Which brand scores better specifically for skin soothing and sensitivity according to review themes?

La Roche-Posay scores better specifically for skin soothing and sensitivity according to review themes.

## Research behind their key ingredients

- [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Final report on the safety assessment of Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate](https://pubmed.ncbi.nlm.nih.gov/11766131/) Benzyl alcohol · International Journal of Toxicology, 2001
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate molecule · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol, Vitamin b5 · American Journal of Clinical Dermatology, 2002
- [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007
- [Regulatory effects of Lactobacillus plantarum-GMNL6 on human skin health by improving skin microbiome](https://pubmed.ncbi.nlm.nih.gov/33526970/) Lactobacillus · International Journal of Medical Sciences, 2021
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Tocopherol, Ascorbic acid, Tocopherol vitamin e · Journal of Cosmetic Dermatology, 2020
- [Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/27261203/) Retinol · International Journal of Cosmetic Science, 2017
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Retinol · The British Journal of Dermatology, 2019
- [Vesicular carriers containing phenylethyl resorcinol for topical delivery system; liposomes, transfersomes and invasomes](https://pubmed.ncbi.nlm.nih.gov/32104421/) Phenylethyl resorcinol · Asian Journal of Pharmaceutical Sciences, 2018
- [Moisturizing and Antiinflammatory Properties of Cosmetic Formulations Containing Centella asiatica Extract](https://pubmed.ncbi.nlm.nih.gov/27168678/) Madecassoside · Indian Journal of Pharmaceutical Sciences, 2016
- [Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin](https://pubmed.ncbi.nlm.nih.gov/33037252/) Squalane · Scientific Reports, 2020
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf extract · Clinical Pharmacology, 2018
- [Vitamin C mesotherapy versus topical application for gingival hyperpigmentation: a clinical and histopathological study](https://pubmed.ncbi.nlm.nih.gov/33966113/) Ascorbic acid · Clinical Oral Investigations, 2021
- [Ethosomes of Phenylethyl Resorcinol as Vesicular Delivery System for Skin Lightening Applications](https://pubmed.ncbi.nlm.nih.gov/28804723/) Phenylethyl resorcinol · BioMed Research International, 2017
- [Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate-irritated skin](https://pubmed.ncbi.nlm.nih.gov/18717861/) Ceramide-3, Ceramide np · International Journal of Dermatology, 2008
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Tocopherol, Ascorbic acid, Tocopherol vitamin e · Journal of Cosmetic Dermatology, 2020
- [Efficacy of probiotic-derived lotion from Lactobacillus paracasei MSMC 39-1 in mild to moderate acne vulgaris, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/35384257/) Lactobacillus · Journal of Cosmetic Dermatology, 2022
- [Clinical, biometric and structural evaluation of the long-term effects of a topical treatment with ascorbic acid and madecassoside in photoaged human skin](https://pubmed.ncbi.nlm.nih.gov/18503551/) Centella asiatica leaf extract · Experimental Dermatology, 2008
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin, Madecassoside · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [The Effects of a Standardized Extract of Centella asiatica on Postlaser Resurfacing Wound Healing on the Face: A Split-Face, Double-Blind, Randomized, Placebo-Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/32310680/) Madecassoside · Journal of Alternative and Complementary Medicine, 2020
- [Prevention and Reduction of Atrophic Acne Scars with Adapalene 0.3%/Benzoyl Peroxide 2.5% Gel in Subjects with Moderate or Severe Facial Acne: Results of a 6-Month Randomized, Vehicle-Controlled Trial Using Intra-Individual Comparison](https://pubmed.ncbi.nlm.nih.gov/29549588/) Adapalene usp retinoid acne treatment, Adapalene · American Journal of Clinical Dermatology, 2018
- [Efficacy and Safety of a Fixed-Dose Clindamycin Phosphate 1.2%, Benzoyl Peroxide 3.1%, and Adapalene 0.15% Gel for Moderate-to-Severe Acne: A Randomized Phase II Study of the First Triple-Combination Drug](https://pubmed.ncbi.nlm.nih.gov/34674160/) Adapalene, Adapalene usp retinoid acne treatment · American Journal of Clinical Dermatology, 2022
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol, Vitamin b5 · The Journal of Dermatological Treatment, 2017
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Adenosine-loaded dissolving microneedle patches to improve skin wrinkles, dermal density, elasticity and hydration](https://pubmed.ncbi.nlm.nih.gov/29574973/) Adenosine · International Journal of Cosmetic Science, 2018
- [A topical gel of tea tree oil nanoemulsion containing adapalene versus adapalene marketed gel in patients with acne vulgaris: a randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/34251536/) Adapalene, Adapalene usp retinoid acne treatment · Archives of Dermatological Research, 2022
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Panthenol, Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Gluconolactone · Clinical, Cosmetic and Investigational Dermatology, 2019
- [Systematic Study of Paeonol/Madecassoside Co-Delivery Nanoemulsion Transdermal Delivery System for Enhancing Barrier Repair and Anti-Inflammatory Efficacy](https://pubmed.ncbi.nlm.nih.gov/37446936/) Centella asiatica leaf extract, Madecassoside · Molecules, 2023
- [A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne](https://pubmed.ncbi.nlm.nih.gov/1303072/) Gluconolactone · The Australasian Journal of Dermatology, 1992
- [Efficacy of olive leaf extract-containing cream for facial rejuvenation: A pilot study](https://pubmed.ncbi.nlm.nih.gov/32333467/) Olive leaf extract · Journal of Cosmetic Dermatology, 2020
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [Biomimetic hyaluronic acid-stabilized zinc oxide nanoparticles in acne treatment: A preclinical and clinical approach](https://pubmed.ncbi.nlm.nih.gov/40254135/) Zinc · Journal of Controlled Release, 2025
- [A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid](https://pubmed.ncbi.nlm.nih.gov/34348350/) Ceramide-3, Ceramide np · Skin Pharmacology and Physiology, 2022
- [Clay jojoba oil facial mask for lesioned skin and mild acne--results of a prospective, observational pilot study](https://pubmed.ncbi.nlm.nih.gov/22585103/) Argilla · Forschende Komplementarmedizin, 2012
- [Efficacy and safety of moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese versus 0.02% triamcinolone acetonide cream in decreasing adverse reaction and downtime after ablative fractional carbon dioxide laser resurfacing: A split-face, double-blinded, randomized, controlled trial](https://pubmed.ncbi.nlm.nih.gov/30945430/) Centella asiatica leaf extract · Journal of Cosmetic Dermatology, 2019
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Comparison of skin calming effects of cosmetic products containing 4-t-butylcyclohexanol or acetyl dipeptide-1 cetyl ester on capsaicin-induced facial stinging in volunteers with sensitive skin](https://pubmed.ncbi.nlm.nih.gov/26805418/) Neurosensine · Journal of the European Academy of Dermatology and Venereology, 2016
- [A dermocosmetic containing bakuchiol, Ginkgo biloba extract and mannitol improves the efficacy of adapalene in patients with acne vulgaris: result from a controlled randomized trial](https://pubmed.ncbi.nlm.nih.gov/25914553/) Ginkgo biloba extract · Clinical, Cosmetic and Investigational Dermatology, 2015
- [2-Mercaptonicotinoyl glycine prevents UV-induced skin darkening and delayed tanning in healthy subjects: A randomized controlled clinical study](https://pubmed.ncbi.nlm.nih.gov/38372022/) 2-mercaptonicotinoyl glycine · Journal of Cosmetic Dermatology, 2024
- [A Bayesian network meta-analysis of 14 molecules inhibiting UV daylight-induced pigmentation](https://pubmed.ncbi.nlm.nih.gov/38433524/) 2-mercaptonicotinoyl glycine · Journal of the European Academy of Dermatology and Venereology, 2024
- [Clindamycin phosphate 1.2%/adapalene 0.15%/benzoyl peroxide 3.1% gel for moderate-to-severe acne: Efficacy and safety results from two randomized phase 3 trials](https://pubmed.ncbi.nlm.nih.gov/37656094/) Adapalene · Journal of the American Academy of Dermatology, 2023
- [Efficacy and Tolerability of Topical Nicotinamide Plus Antibacterial Adhesive Agents and Zinc-Pyrrolidone Carboxylic Acid Versus Placebo as an Adjuvant Treatment for Moderate Acne Vulgaris in Indonesia: A Multicenter, Double-blind, Randomized, Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/32983333/) Zinc pca · The Journal of Clinical and Aesthetic Dermatology, 2020
- [Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/35775872/) Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022
- [Effects of 1,3-propanediol associated, or not, with butylene glycol and/or glycerol on skin hydration and skin barrier function](https://pubmed.ncbi.nlm.nih.gov/37699769/) Propanediol · International Journal of Cosmetic Science, 2024
- [Assessment of the Benefit of a Deep Cleansing Gel Containing Salicylic Acid 2%, Zinc Gluconate 0.2% and Lipohydroxy Acids 0.05% in Patients with Mild to Moderate Truncal Acne: Results from an Exploratory Study](https://pubmed.ncbi.nlm.nih.gov/36698447/) Zinc gluconate · Clinical, Cosmetic and Investigational Dermatology, 2023
- [Subclinical, non-erythematous irritation with an open assay model (washing): sodium lauryl sulfate (SLS) versus sodium laureth sulfate (SLES)](https://pubmed.ncbi.nlm.nih.gov/11278060/) Sodium laureth sulfate · Food and Chemical Toxicology, 2001
- [A Rose Extract Protects the Skin against Stress Mediators: A Potential Role of Olfactory Receptors](https://pubmed.ncbi.nlm.nih.gov/33081083/) Rose bud · Molecules, 2020
- [Clinical evaluation of the efficacy of a facial serum containing dioic acid, glycolic acid, salicylic acid, LHA, citric acid, and HEPES in treating post-inflammatory hyperchromia and controlling oily skin in patients with acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/33617668/) Capryloyl salicylic acid, Citric acid · Journal of Cosmetic Dermatology, 2021
- [Amino acid complex (AAComplex) benefits in cosmetic products: In vitro and in vivo clinical studies](https://pubmed.ncbi.nlm.nih.gov/34694692/) Complex amino acid · Journal of Cosmetic Dermatology, 2022
- [Is benzyl alcohol a significant contact sensitizer?](https://pubmed.ncbi.nlm.nih.gov/35080274/) Benzyl alcohol · Journal of the European Academy of Dermatology and Venereology, 2022
- [Clinical tolerance and efficacy of capryloyl salicylic acid peel compared to a glycolic acid peel in subjects with fine lines/wrinkles and hyperpigmented skin](https://pubmed.ncbi.nlm.nih.gov/19146601/) Capryloyl salicylic acid · Journal of Cosmetic Dermatology, 2008
- [Comparative benefit of two thermal spring waters after photodynamic therapy procedure](https://pubmed.ncbi.nlm.nih.gov/17348993/) La roche-posay thermal spring water · Journal of Cosmetic Dermatology, 2007
- [Zinc(II) Complexes of Amino Acids as New Active Ingredients for Anti-Acne Dermatological Preparations](https://pubmed.ncbi.nlm.nih.gov/33561977/) Complex amino acid · International Journal of Molecular Sciences, 2021
- [Effect of a botanical cleansing lotion on skin sebum and erythema of the face: A randomized controlled blinded half-side comparison](https://pubmed.ncbi.nlm.nih.gov/30022595/) Willow bark extract · Journal of Cosmetic Dermatology, 2019
- [Anti-Inflammatory Effect of a Novel Topical Herbal Composition (VEL-091604) Consisting of Gentian Root, Licorice Root and Willow Bark Extract](https://pubmed.ncbi.nlm.nih.gov/30690691/) Willow bark extract · Planta Medica, 2019
- [Development of solid lipid microparticles (SLMs) containing asiatic acid for topical treatment of acne: Characterization, stability, in vitro and in vivo anti-acne assessment](https://pubmed.ncbi.nlm.nih.gov/38460769/) Centella asiatica leaf extract · International Journal of Pharmaceutics, 2024
- [Comprehensive assessment of the efficacy and safety of a clay mask in oily and acne skin](https://pubmed.ncbi.nlm.nih.gov/38009030/) Argilla · Skin Research and Technology, 2023
- [Noninvasive evaluation of the influence of aucubin-containing cosmetic macroemulsion on selected skin parameters](https://pubmed.ncbi.nlm.nih.gov/32750209/) Plantago extract · Journal of Cosmetic Dermatology, 2021
- [A dermocosmetic formulation containing Vichy volcanic mineralizing water, Vitreoscilla filiformis extract, niacinamide, hyaluronic acid, and vitamin E regenerates and repairs acutely stressed skin](https://pubmed.ncbi.nlm.nih.gov/34979590/) Vitreoscilla ferment · Journal of the European Academy of Dermatology and Venereology, 2022
- [Comparison of methods for assessing photoprotection against ultraviolet A in vivo](https://pubmed.ncbi.nlm.nih.gov/3819071/) Butyl methoxydibenzoylmethane · Journal of the American Academy of Dermatology, 1987
- [Using ordered mesoporous silica SBA-15 to limit cutaneous penetration and transdermal permeation of organic UV filters](https://pubmed.ncbi.nlm.nih.gov/31437563/) Butyl methoxydibenzoylmethane · International Journal of Pharmaceutics, 2019
- [A controlled, three-part trial to investigate the barrier function and skin hydration properties of six skin protectants](https://pubmed.ncbi.nlm.nih.gov/16439809/) Dimethicone · Ostomy/wound Management, 2005
- [Enhancing Photoprotection and Mitigating Ex Vivo Stratum Corneum Oxidative Stress: A Multifunctional Strategy Combining Rosmarinic Acid with UVB Filters](https://pubmed.ncbi.nlm.nih.gov/40227214/) Octocrylene · Antioxidants, 2025
- [A randomized controlled trial to compare the effectiveness and safety of adsorbent lotion containing tapioca starch, spent grain wax, Butyrospermum parkii extract, argania spinosa kernel oil, aloe barbadensis, rosehip oil, and allantoin with a low-potency topical corticosteroid in the treatment of intertrigo](https://pubmed.ncbi.nlm.nih.gov/33811776/) Shea butter · Journal of Cosmetic Dermatology, 2022
- [Clinical efficacy and safety of nano-microneedle-assisted phenylethyl resorcinol for the treatment of infraorbital dark circles](https://pubmed.ncbi.nlm.nih.gov/32783330/) Phenylethyl resorcinol · Journal of Cosmetic Dermatology, 2021
- [Lactobionic acid in a natural alkylpolyglucoside-based vehicle: assessing safety and efficacy aspects in comparison to glycolic acid](https://pubmed.ncbi.nlm.nih.gov/20367666/) Pha polyhydroxy acid · Journal of Cosmetic Dermatology, 2010
- [Topical prevention from high energy visible light-induced pigmentation by 2-mercaptonicotinoyl glycine, but not by ascorbic acid antioxidant: 2 randomized controlled trials](https://pubmed.ncbi.nlm.nih.gov/41142247/) 2-mercaptonicotinoyl glycine · Frontiers in Pharmacology, 2025
- [Rosa gallica and its active compound, cyanidin-3,5-O-diglucoside, improve skin hydration via the GLK signaling pathway](https://pubmed.ncbi.nlm.nih.gov/36573713/) Rose bud · BioFactors, 2023
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol, Vitamin b5 · Journal of Cosmetic Dermatology, 2025
- [A multicenter, double-blind study to evaluate the efficacy and safety of 2 treatments in participants with mild to moderate acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/22838094/) Micro-exfoliating lha · Cutis, 2012
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026
- [Propanediol (and) Caprylic Acid (and) Xylitol as a New Single Topical Active Ingredient against Acne: In Vitro and In Vivo Efficacy Assays](https://pubmed.ncbi.nlm.nih.gov/34771112/) Propanediol · Molecules, 2021
- [Clinical efficacy of herbal extract cream on the skin hydration, elasticity, thickness, and dermis density for aged skin: A randomized controlled double-blind study](https://pubmed.ncbi.nlm.nih.gov/30636339/) Botanical extracts · Journal of Cosmetic Dermatology, 2019
- [Protective properties of Avène Thermal Spring Water on biomechanical, ultrastructural and clinical parameters of human skin](https://pubmed.ncbi.nlm.nih.gov/32870553/) Prebiotic thermal water, La roche-posay thermal spring water, Thermal spring water · Journal of the European Academy of Dermatology and Venereology, 2020
- [Comparison of clindamycin 1% and benzoyl peroxide 5% gel to a novel composition containing salicylic acid, capryloyl salicylic acid, HEPES, glycolic acid, citric acid, and dioic acid in the treatment of acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/23545907/) Capryloyl salicylic acid · Journal of Drugs in Dermatology, 2013
- [Histometric assessment of the age-related skin response to 2-hydroxy-5-octanoyl benzoic acid](https://pubmed.ncbi.nlm.nih.gov/9603669/) Capryloyl salicylic acid · Skin Pharmacology and Applied Skin Physiology, 1998
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery](https://pubmed.ncbi.nlm.nih.gov/36279763/) Hydrolyzed hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022
- [Evaulation of irritation potential of surfactant mixtures](https://pubmed.ncbi.nlm.nih.gov/18503452/) Sodium laureth sulfate · International Journal of Cosmetic Science, 1999
- [Influence of the emulsifier on nanostructure and clinical application of liquid crystalline emulsions](https://pubmed.ncbi.nlm.nih.gov/36918671/) Camellia seed oil · Scientific Reports, 2023
- [Development and efficacy assessments of tea seed oil makeup remover](https://pubmed.ncbi.nlm.nih.gov/27988044/) Camellia seed oil · Annales Pharmaceutiques Francaises, 2017
- [Impact of Hydrocolloid Dressing and Moisturizing Cream as Facial Skin Protectants Among Health Care Workers](https://pubmed.ncbi.nlm.nih.gov/38771104/) Dimethicone · Military Medicine, 2024
- [Effects of Malaysian thermal spring water as adjunct therapy for mild to moderate acne vulgaris - a prospective, randomised, controlled, split face study](https://pubmed.ncbi.nlm.nih.gov/38553920/) Prebiotic thermal water, La roche-posay thermal spring water, Thermal spring water, La roche-posay prebiotic thermal water, Thermal water · The Medical Journal of Malaysia, 2024
- [Efficacy and safety of a facial serum and a mask containing salicylic acid and lipohydroxy acid in acne management: A randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/36999489/) Micro-exfoliating lha · Journal of Cosmetic Dermatology, 2023
- [Facial disbiosis and UV filters](https://pubmed.ncbi.nlm.nih.gov/39499337/) Ethylhexyl salicylate · Archives of Dermatological Research, 2024
- [Rapid and Visible Efficacy of a Dermocosmetic in Acne Patients With Fair Skin Phototypes: Results of a Randomized Split-Face Study](https://pubmed.ncbi.nlm.nih.gov/41487026/) Zinc gluconate · Journal of Cosmetic Dermatology, 2026
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- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Shea butter, Butyrospermum parkii butter shea butter · Lasers in Medical Science, 2025
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## The brands

- French skincare: [La Roche-Posay](https://lovi.care/skincare/fr/brands/la-roche-posay)
- Skincare: [Grown Alchemist](https://lovi.care/skincare/fr/brands/grown-alchemist)

## More comparisons

- [SKIN1004 vs La Roche-Posay](https://lovi.care/skincare/fr/compare/skin1004-vs-la-roche-posay)
- [SKIN1004 vs Grown Alchemist](https://lovi.care/skincare/fr/compare/skin1004-vs-grown-alchemist)
- [Anua vs La Roche-Posay](https://lovi.care/skincare/fr/compare/anua-vs-la-roche-posay)
- [Anua vs Grown Alchemist](https://lovi.care/skincare/fr/compare/anua-vs-grown-alchemist)
- [Medicube vs La Roche-Posay](https://lovi.care/skincare/fr/compare/medicube-vs-la-roche-posay)
- [Medicube vs Grown Alchemist](https://lovi.care/skincare/fr/compare/medicube-vs-grown-alchemist)
- [The Ordinary vs La Roche-Posay](https://lovi.care/skincare/fr/compare/the-ordinary-vs-la-roche-posay)
- [The Ordinary vs Grown Alchemist](https://lovi.care/skincare/fr/compare/the-ordinary-vs-grown-alchemist)
- [Beauty of Joseon vs La Roche-Posay](https://lovi.care/skincare/fr/compare/beauty-of-joseon-vs-la-roche-posay)
- [Beauty of Joseon vs Grown Alchemist](https://lovi.care/skincare/fr/compare/beauty-of-joseon-vs-grown-alchemist)
- [COSRX vs La Roche-Posay](https://lovi.care/skincare/fr/compare/cosrx-vs-la-roche-posay)
- [COSRX vs Grown Alchemist](https://lovi.care/skincare/fr/compare/cosrx-vs-grown-alchemist)
- [CeraVe vs La Roche-Posay](https://lovi.care/skincare/fr/compare/cerave-vs-la-roche-posay)
- [CeraVe vs Grown Alchemist](https://lovi.care/skincare/fr/compare/cerave-vs-grown-alchemist)
- [La Roche-Posay vs Dr. Althea](https://lovi.care/skincare/fr/compare/la-roche-posay-vs-dr-althea)
- [La Roche-Posay vs Some By Mi](https://lovi.care/skincare/fr/compare/la-roche-posay-vs-some-by-mi)
- [La Roche-Posay vs Torriden](https://lovi.care/skincare/fr/compare/la-roche-posay-vs-torriden)
- [La Roche-Posay vs celimax](https://lovi.care/skincare/fr/compare/la-roche-posay-vs-celimax)
- [La Roche-Posay vs Purito](https://lovi.care/skincare/fr/compare/la-roche-posay-vs-purito)
- [La Roche-Posay vs Cetaphil](https://lovi.care/skincare/fr/compare/la-roche-posay-vs-cetaphil)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/la-roche-posay-vs-grown-alchemist
- United Kingdom: https://lovi.care/skincare/uk/compare/la-roche-posay-vs-grown-alchemist
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- Germany: https://lovi.care/skincare/de/compare/la-roche-posay-vs-grown-alchemist
- France: https://lovi.care/skincare/fr/compare/la-roche-posay-vs-grown-alchemist (this page)
- Italy: https://lovi.care/skincare/it/compare/la-roche-posay-vs-grown-alchemist
- Netherlands: https://lovi.care/skincare/nl/compare/la-roche-posay-vs-grown-alchemist
- Spain: https://lovi.care/skincare/es/compare/la-roche-posay-vs-grown-alchemist
- Canada: https://lovi.care/skincare/ca/compare/la-roche-posay-vs-grown-alchemist
- Australia: https://lovi.care/skincare/au/compare/la-roche-posay-vs-grown-alchemist
- Singapore: https://lovi.care/skincare/sg/compare/la-roche-posay-vs-grown-alchemist
- Saudi Arabia: https://lovi.care/skincare/sa/compare/la-roche-posay-vs-grown-alchemist
- United Arab Emirates: https://lovi.care/skincare/ae/compare/la-roche-posay-vs-grown-alchemist