# La Roche-Posay vs Clarins

Page: https://lovi.care/skincare/fr/compare/la-roche-posay-vs-clarins

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for France.

La Roche-Posay and Clarins are two respected French skincare houses offering targeted solutions for diverse complexions. The former is known for nourishing [serums](https://lovi.care/skincare/fr/ingredients/serum), rich moisturizers, gentle cleansers, and targeted eye products formulated with [glycerin](https://lovi.care/skincare/fr/ingredients/glycerin), soothing [thermal water](https://lovi.care/skincare/fr/ingredients/thermal-water), and [niacinamide](https://lovi.care/skincare/fr/ingredients/niacinamide), suiting mature skin and skin with dark spots best. Meanwhile, the latter is celebrated for nourishing moisturizers, targeted serums, delicate eye products, and refreshing toners harnessing soothing shea and replenishing squalane to best suit sensitive and mature skin. These brands ultimately differ in their key botanical and scientific elements, with both delivering carefully balanced care.

La Roche-Posay is a French skincare brand founded in 1975 and owned by L'Oréal S.A. since 1989.

[laroche-posay.com.au](https://www.laroche-posay.com.au/our-commitments/history.html) [fr.wikipedia.org](https://fr.wikipedia.org/wiki/L%27Or%C3%A9al)

Clarins is a French skincare brand founded in 1954 and owned by Famille C (Groupe Clarins).

[groupeclarins.com](https://www.groupeclarins.com/our-governance/) [en.wikipedia.org](https://en.wikipedia.org/wiki/Clarins) [happi.com](https://www.happi.com/top-company-profile/clarins/)

This page compares some of the most popular La Roche-Posay and Clarins products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg3acabb2f82).

### Popular La Roche-Posay vs Clarins products

#### La Roche-Posay

- [Toleriane Double Repair Face Moisturizer](https://lovi.care/skincare/fr/p/la-roche-posay/toleriane-double-repair-face-moisturizer/for/oily-acne-prone-skin) — High fit
- [Cicaplast Baume B5+](https://lovi.care/skincare/fr/p/la-roche-posay/cicaplast-baume-b5/for/sensitive-skin) — Superior fit — [€17.78 at Amazon](https://www.amazon.fr/dp/B07SNCRCP1?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1)
- [Mela B3 Serum](https://lovi.care/skincare/fr/p/la-roche-posay/mela-b3-serum/for/acne-prone-skin) — High fit — [€55.61 at Amazon](https://www.amazon.fr/dp/B0BQF5X6FR?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1)
- [Retinol B3 Serum](https://lovi.care/skincare/fr/p/la-roche-posay/retinol-b3-serum/for/dark-spots) — Average fit — [€44.16 at Lookfantastic](https://www.lookfantastic.fr/p/la-roche-posay-retinol-b3-anti-wrinkle-anti-ageing-serum-with-retinol-and-vitamin-b3-suitable-for-sensitive-skin-30ml/12382710/)
- [Effaclar Medicated Gel Cleanser](https://lovi.care/skincare/fr/p/la-roche-posay/effaclar-medicated-gel-cleanser/for/acne-prone-skin) — High fit — [€16.90 at Notino](https://www.notino.fr/la-roche-posay/effaclar-gel-purifiant-en-profondeur-pour-peaux-grasses-sensibles/p-75718/)
- [Hyalu B5 Serum](https://lovi.care/skincare/fr/p/la-roche-posay/hyalu-b5-serum/for/sensitive-skin) — High fit — [€40.00 at Amazon](https://www.amazon.fr/dp/B0CZ3WBPTJ?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1)
- [Lipikar AP+M Triple Repair Moisturizing Cream](https://lovi.care/skincare/fr/p/la-roche-posay/lipikar-ap-m-triple-repair-moisturizing-cream/for/dry-skin) — High fit — [€25.42 at Amazon](https://www.amazon.fr/dp/B0849KTG44?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1)
- [Anthelios](https://lovi.care/skincare/fr/p/la-roche-posay/anthelios/for/dark-spots) — Superior fit — [€26.00 at Amazon](https://www.amazon.fr/dp/B0GZK2X1H4?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1)

#### Clarins

- [Double Serum](https://lovi.care/skincare/fr/p/clarins/double-serum/for/sensitive-skin) — High fit — [€57.50 at Notino](https://www.notino.fr/clarins/double-serum-serum-intense-anti-age-6978018/p-16257503/)
- [Total Eye Lift](https://lovi.care/skincare/fr/p/clarins/total-eye-lift/for/mature-skin) — Superior fit — [€54.10 at Notino](https://www.notino.fr/clarins/total-eye-lift-creme-yeux-anti-rides-recharge/p-16360815/)
- [Double Serum Eye](https://lovi.care/skincare/fr/p/clarins/double-serum-eye/for/dry-sensitive-skin) — High fit — [€86.50 at Notino](https://www.notino.fr/clarins/double-serum-eye-serum-anti-rides-contour-des-yeux-effet-nourrissant-7136326/p-16389300/)
- [Cryo-Flash Cream-Mask](https://lovi.care/skincare/fr/p/clarins/cryo-flash-cream-mask/for/dry-sensitive-skin) — High fit — [€65.90 at Notino](https://www.notino.fr/clarins/cryo-flash-mask-masque-hydratant-fermete-et-anti-age/p-16199984/)
- [Beauty Flash Balm](https://lovi.care/skincare/fr/p/clarins/beauty-flash-balm/for/dry-skin) — Warning fit — [€30.50 at Notino](https://www.notino.fr/clarins/beauty-flash-balm-creme-de-jour-illuminatrice-effet-hydratant-pour-peaux-fatiguees/p-16122610/)
- [Multi-Active Jour](https://lovi.care/skincare/fr/p/clarins/multi-active-jour/for/mature-skin) — Average fit — [€51.50 at Notino](https://www.notino.fr/clarins/multi-active-day-cream-all-skin-types-creme-lissante-et-illuminatrice-pour-tous-types-de-peau/p-16232224/)
- [Double Serum Light Texture](https://lovi.care/skincare/fr/p/clarins/double-serum-light-texture/for/dry-sensitive-skin) — High fit — [€71.50 at Notino](https://www.notino.fr/clarins/double-serum-light-texture-serum-intense-anti-age-7061452/p-16300238/)
- [Extra-Firming Neck & Décolleté Cream](https://lovi.care/skincare/fr/p/clarins/extra-firming-neck-and-decollete-cream/for/dry-skin) — Average fit — [€9.49 at Amazon](https://www.amazon.fr/dp/B0GRHD15CC?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1)

## People Say

La Roche-Posay

Clarins

- Hydration and Moisture Mostly Mentioned Mostly Mentioned “absorbs instantly — La Roche-Posay Toleriane Double Repair Face Moisturizer” “skin feels plump — La Roche-Posay Hyalu B5 Serum” “skin drinks it up — Clarins Double Serum” “keeps skin moist — Clarins Multi-Active Jour”
- Gentle on Sensitive Skin Mostly Mentioned Rarely Noted “Great retinol for beginners — La Roche-Posay Retinol B3 Serum” “Only cream that doesn't sting — La Roche-Posay Toleriane Dermallergo Eye Cream” “Calmed my skin after a chemical peel — La Roche-Posay Thermal Spring Water” “no irritation for contact wearers — Clarins Total Eye Lift”
- Fast Absorption and Lightweight Sometimes Noted Often Mentioned “absorbs immediately — Clarins Double Serum Eye” “sinks in immediately — Clarins Double Serum Light Texture” “absorbs quickly without grease — Clarins Total Eye Lift” “absorbs in seconds — La Roche-Posay Anthelios”
- Skin Texture and Smoothing Often Mentioned Often Mentioned “Skin feels smoother — La Roche-Posay Retinol B3 Serum” “softens forehead lines — La Roche-Posay Hyalu B5 Serum” “neck feels smoother — Clarins Extra-Firming Neck & Décolleté Cream” “makes skin silky smooth — Clarins Hydrating Toning Lotion”
- Brightening and Dark Spots Sometimes Noted Often Mentioned “skin looks brighter immediately — Clarins Cryo-Flash Cream-Mask” “Gives off the most stunning natural radiance I've ever come across. — Clarins Beauty Flash Balm” “radiant youthful glow — Clarins Multi-Active Jour” “skin looks brighter — La Roche-Posay Mela B3 Serum”
- Texture and Quality Sometimes Noted Often Mentioned “melting non-oily texture — Clarins Extra-Firming Neck & Décolleté Cream” “Creamy texture feels luxurious upon application — Clarins Extra-Firming Day Cream” “feels like silk — Clarins Double Serum” “lightweight and absorbs quickly — La Roche-Posay Mela B3 Serum”
- Price and Value Sometimes Noted Mostly Mentioned “expensive for the size — La Roche-Posay Hyalu B5 Serum” “Too expensive for the size — La Roche-Posay Toleriane Dermallergo Eye Cream” “Tube is tiny for the price — La Roche-Posay Cicaplast Gel B5” “way too expensive — Clarins Double Serum”
- Fragrance and Scent Sometimes Noted Often Mentioned “scent is awful — La Roche-Posay Mela B3 Serum” “overwhelming floral smell — La Roche-Posay Hyalu B5 Serum” “Smells like cheap fragrance — La Roche-Posay Retinol B3 Serum” “smells like perfume — Clarins Multi-Active Jour”
- Packaging and Pump Issues Often Mentioned Often Mentioned “pump stops working — La Roche-Posay Lipikar AP+M Triple Repair Moisturizing Cream” “Pump stopped working halfway — La Roche-Posay Toleriane Dermallergo Eye Cream” “dispenses too much product — Clarins Total Eye Lift” “dispenses too much — Clarins Double Serum Eye”
- Product Pilling and Texture Issues Often Mentioned Rarely Noted “sat on top of skin — Clarins Double Serum” “Described as having a sticky, gel-like texture. — Clarins Beauty Flash Balm” “leaves a sticky film — Clarins Hydrating Toning Lotion” “pills like crazy — La Roche-Posay Toleriane Double Repair Face Moisturizer”

### La Roche-Posay vs Clarins routines for dry skin

#### La Roche-Posay-focused routine

- Cleanser: [Toleriane Double Repair Face Moisturizer](https://lovi.care/skincare/fr/p/la-roche-posay/toleriane-double-repair-face-moisturizer/for/dry-skin) — Average fit — Morning · Evening · Once a week
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/fr/p/cosrx/propolis-synergy-toner/for/dry-skin) — Superior fit — [€18.55 at Amazon](https://www.amazon.fr/dp/B089SCWPJR?tag=lovi-care-web-routine05-21&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [Pure Vitamin C Cream](https://lovi.care/skincare/fr/p/la-roche-posay/pure-vitamin-c-cream/for/dry-skin) — Superior fit — [€62.95 at Amazon](https://www.amazon.fr/dp/B07VGLYZBH?tag=lovi-care-web-routine05-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Anthelios](https://lovi.care/skincare/fr/p/la-roche-posay/anthelios/for/dry-skin) — High fit — [€26.00 at Amazon](https://www.amazon.fr/dp/B0GZK2X1H4?tag=lovi-care-web-routine05-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Respectissime Waterproof Eye Makeup Remover](https://lovi.care/skincare/fr/p/la-roche-posay/respectissime-waterproof-eye-makeup-remover/for/dry-skin) — High fit — [€13.80 at Lookfantastic](https://www.lookfantastic.fr/p/la-roche-posay-toleriane-respectissime-waterproof-eye-make-up-remover-125ml/11355388/) — Evening · Once a week
- Serum or Treatment: [Cicaplast Baume B5+](https://lovi.care/skincare/fr/p/la-roche-posay/cicaplast-baume-b5/for/dry-skin) — High fit — [€17.78 at Amazon](https://www.amazon.fr/dp/B07SNCRCP1?tag=lovi-care-web-routine05-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Nourishing Mask: [Anua Heartleaf 77% Soothing Sheet Mask](https://lovi.care/skincare/fr/p/anua/heartleaf-77-soothing-sheet-mask/for/dry-skin) — Superior fit — [€19.90 at Amazon](https://www.amazon.fr/dp/B0H5JZX1Z1?tag=lovi-care-web-routine05-21&linkCode=osi&th=1&psc=1) — Once a week

#### Clarins-focused routine

- Cleanser: [Gentle Foaming Cleanser](https://lovi.care/skincare/fr/p/clarins/gentle-foaming-cleanser/for/dry-skin) — Average fit — [€18.50 at Notino](https://www.notino.fr/clarins/cleansing-soothing-gentle-foaming-cleanser-mousse-demaquillante-douce-avec-effets-apaisants/p-16261768/) — Morning · Evening · Once a week
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/fr/p/cosrx/propolis-synergy-toner/for/dry-skin) — Superior fit — [€18.55 at Amazon](https://www.amazon.fr/dp/B089SCWPJR?tag=lovi-care-web-routine05-21&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [Hydra-Essentiel Silky Cream](https://lovi.care/skincare/fr/p/clarins/hydra-essentiel-silky-cream/for/dry-skin) — Superior fit — [€32.00 at Notino](https://www.notino.fr/clarins/hydra-essentielha2-silky-cream-spf-15-creme-soyeuse-hydratante-spf-15/p-16173388/) — Morning · Evening · Once a week
- SPF: [Purito Daily Soft Touch Sunscreen](https://lovi.care/skincare/fr/p/purito/daily-soft-touch-sunscreen/for/dry-skin) — Superior fit — [€12.98 at Amazon](https://www.amazon.fr/dp/B0CYCBVBTR?tag=lovi-care-web-routine05-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Total Cleansing Oil](https://lovi.care/skincare/fr/p/clarins/total-cleansing-oil/for/dry-skin) — High fit — [€19.50 at Notino](https://www.notino.fr/clarins/cleansing-total-cleansing-oil-huile-demaquillante-purifiante-visage/p-16229349/) — Evening · Once a week
- Serum or Treatment: [BRIGHT PLUS](https://lovi.care/skincare/fr/p/clarins/bright-plus/for/dry-skin) — Average fit — Evening · Once a week
- Nourishing Mask: [Cryo-Flash Cream-Mask](https://lovi.care/skincare/fr/p/clarins/cryo-flash-cream-mask/for/dry-skin) — High fit — [€65.90 at Notino](https://www.notino.fr/clarins/cryo-flash-mask-masque-hydratant-fermete-et-anti-age/p-16199984/) — Once a week

[See multi-brand routine · 98% fit](https://lovi.care/skincare/fr/skin/dry-skin)

### La Roche-Posay vs Clarins routines for oily skin

#### La Roche-Posay-focused routine

- Cleanser: [Effaclar Medicated Gel Cleanser](https://lovi.care/skincare/fr/p/la-roche-posay/effaclar-medicated-gel-cleanser/for/oily-skin) — High fit — [€16.90 at Notino](https://www.notino.fr/la-roche-posay/effaclar-gel-purifiant-en-profondeur-pour-peaux-grasses-sensibles/p-75718/) — Morning · Evening · Once a week
- Hydrating Toner: [Some By Mi Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/fr/p/some-by-mi/snail-truecica-miracle-repair-toner/for/oily-skin) — Superior fit — [€19.99 at Amazon](https://www.amazon.fr/dp/B08125WDCF?tag=lovi-care-web-routine05-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Toleriane Dermallergo Night Cream](https://lovi.care/skincare/fr/p/la-roche-posay/toleriane-dermallergo-night-cream/for/oily-skin) — High fit — [€22.00 at Amazon](https://www.amazon.fr/dp/B09DPHF489?tag=lovi-care-web-routine05-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Anthelios](https://lovi.care/skincare/fr/p/la-roche-posay/anthelios/for/oily-skin) — Superior fit — [€26.00 at Amazon](https://www.amazon.fr/dp/B0GZK2X1H4?tag=lovi-care-web-routine05-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Micellar Water Ultra](https://lovi.care/skincare/fr/p/la-roche-posay/micellar-water-ultra/for/oily-skin) — Average fit — [€28.02 at Amazon](https://www.amazon.fr/dp/B01N7T7JKJ?tag=lovi-care-web-routine05-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Pixi Glow Tonic](https://lovi.care/skincare/fr/p/pixi/glow-tonic/for/oily-skin) — Superior fit — [€29.29 at Amazon](https://www.amazon.fr/dp/B09SN5B88W?tag=lovi-care-web-routine05-21&linkCode=osi&th=1&psc=1) — Evening
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/fr/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [€49.00 at Amazon](https://www.amazon.fr/dp/B0D1YJN279?tag=lovi-care-web-routine05-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Effaclar Mask](https://lovi.care/skincare/fr/p/la-roche-posay/effaclar-mask/for/oily-skin) — Average fit — [€21.90 at Notino](https://www.notino.fr/la-roche-posay/effaclar-masque-purifiant-pour-eliminer-les-exces-de-sebum-et-les-pores/p-619783/) — Once a week

#### Clarins-focused routine

- Cleanser: [Gentle Foaming Cleanser](https://lovi.care/skincare/fr/p/clarins/gentle-foaming-cleanser/for/oily-skin) — Average fit — [€18.50 at Notino](https://www.notino.fr/clarins/cleansing-soothing-gentle-foaming-cleanser-mousse-demaquillante-douce-avec-effets-apaisants/p-16261768/) — Morning · Evening · Once a week
- Hydrating Toner: [Some By Mi Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/fr/p/some-by-mi/snail-truecica-miracle-repair-toner/for/oily-skin) — Superior fit — [€19.99 at Amazon](https://www.amazon.fr/dp/B08125WDCF?tag=lovi-care-web-routine05-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Double Serum Light Texture](https://lovi.care/skincare/fr/p/clarins/double-serum-light-texture/for/oily-skin) — Average fit — [€71.50 at Notino](https://www.notino.fr/clarins/double-serum-light-texture-serum-intense-anti-age-7061452/p-16300238/) — Morning · Evening · Once a week
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/fr/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/oily-skin) — Superior fit — [€34.30 at Amazon](https://www.amazon.fr/dp/B0CF22FB86?tag=lovi-care-web-routine05-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Total Cleansing Oil](https://lovi.care/skincare/fr/p/clarins/total-cleansing-oil/for/oily-skin) — Average fit — [€19.50 at Notino](https://www.notino.fr/clarins/cleansing-total-cleansing-oil-huile-demaquillante-purifiante-visage/p-16229349/) — Evening · Once a week
- Cleansing Toner: [Purifying Toning Lotion](https://lovi.care/skincare/fr/p/clarins/purifying-toning-lotion/for/oily-skin) — Average fit — [€18.90 at Notino](https://www.notino.fr/clarins/cleansing-purifying-toning-lotion-lotion-tonique-douce-pour-peaux-mixtes-a-grasses/p-16229346/) — Evening
- Serum or Treatment: [BRIGHT PLUS](https://lovi.care/skincare/fr/p/clarins/bright-plus/for/oily-skin) — Caution fit — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/fr/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [€49.00 at Amazon](https://www.amazon.fr/dp/B0D1YJN279?tag=lovi-care-web-routine05-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask](https://lovi.care/skincare/fr/p/herbivore-botanicals/blue-tansy-bha-and-enzyme-pore-refining-mask/for/oily-skin) — Superior fit — [€79.97 at Amazon](https://www.amazon.fr/dp/B015RRNQCY?tag=lovi-care-web-routine05-21&linkCode=osi&th=1&psc=1) — Once a week

[See multi-brand routine · 97% fit](https://lovi.care/skincare/fr/skin/oily-skin)

### La Roche-Posay vs Clarins routines for combination skin

#### La Roche-Posay-focused routine

- Cleanser: [Effaclar Medicated Gel Cleanser](https://lovi.care/skincare/fr/p/la-roche-posay/effaclar-medicated-gel-cleanser/for/combination-skin) — High fit — [€16.90 at Notino](https://www.notino.fr/la-roche-posay/effaclar-gel-purifiant-en-profondeur-pour-peaux-grasses-sensibles/p-75718/) — Morning · Evening · Once a week
- Hydrating Toner: [Paula's Choice Skin Balancing Pore-Reducing Toner](https://lovi.care/skincare/fr/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — [€36.00 at Amazon](https://www.amazon.fr/dp/B07P7VZ2J9?tag=lovi-care-web-routine05-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Toleriane Dermallergo Night Cream](https://lovi.care/skincare/fr/p/la-roche-posay/toleriane-dermallergo-night-cream/for/combination-skin) — High fit — [€22.00 at Amazon](https://www.amazon.fr/dp/B09DPHF489?tag=lovi-care-web-routine05-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Anthelios](https://lovi.care/skincare/fr/p/la-roche-posay/anthelios/for/combination-skin) — Superior fit — [€26.00 at Amazon](https://www.amazon.fr/dp/B0GZK2X1H4?tag=lovi-care-web-routine05-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Respectissime Waterproof Eye Makeup Remover](https://lovi.care/skincare/fr/p/la-roche-posay/respectissime-waterproof-eye-makeup-remover/for/combination-skin) — Average fit — [€13.80 at Lookfantastic](https://www.lookfantastic.fr/p/la-roche-posay-toleriane-respectissime-waterproof-eye-make-up-remover-125ml/11355388/) — Evening · Once a week
- Cleansing Toner: [Medicube Zero Pore Pad 2.0](https://lovi.care/skincare/fr/p/medicube/zero-pore-pad-2-0/for/combination-skin) — Superior fit — [€17.15 at Amazon](https://www.amazon.fr/dp/B09V7Z4TJG?tag=lovi-care-web-routine05-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Cicaplast Baume B5+](https://lovi.care/skincare/fr/p/la-roche-posay/cicaplast-baume-b5/for/combination-skin) — Average fit — [€17.78 at Amazon](https://www.amazon.fr/dp/B07SNCRCP1?tag=lovi-care-web-routine05-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/fr/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — [€49.00 at Amazon](https://www.amazon.fr/dp/B0D1YJN279?tag=lovi-care-web-routine05-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Effaclar Mask](https://lovi.care/skincare/fr/p/la-roche-posay/effaclar-mask/for/combination-skin) — Average fit — [€21.90 at Notino](https://www.notino.fr/la-roche-posay/effaclar-masque-purifiant-pour-eliminer-les-exces-de-sebum-et-les-pores/p-619783/) — Once a week

#### Clarins-focused routine

- Cleanser: [Gentle Foaming Cleanser](https://lovi.care/skincare/fr/p/clarins/gentle-foaming-cleanser/for/combination-skin) — Average fit — [€18.50 at Notino](https://www.notino.fr/clarins/cleansing-soothing-gentle-foaming-cleanser-mousse-demaquillante-douce-avec-effets-apaisants/p-16261768/) — Morning · Evening · Once a week
- Hydrating Toner: [Paula's Choice Skin Balancing Pore-Reducing Toner](https://lovi.care/skincare/fr/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — [€36.00 at Amazon](https://www.amazon.fr/dp/B07P7VZ2J9?tag=lovi-care-web-routine05-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Double Serum Light Texture](https://lovi.care/skincare/fr/p/clarins/double-serum-light-texture/for/combination-skin) — Average fit — [€71.50 at Notino](https://www.notino.fr/clarins/double-serum-light-texture-serum-intense-anti-age-7061452/p-16300238/) — Morning · Evening · Once a week
- Pre-Cleanser: [Total Cleansing Oil](https://lovi.care/skincare/fr/p/clarins/total-cleansing-oil/for/combination-skin) — Average fit — [€19.50 at Notino](https://www.notino.fr/clarins/cleansing-total-cleansing-oil-huile-demaquillante-purifiante-visage/p-16229349/) — Evening · Once a week
- Cleansing Toner: [Purifying Toning Lotion](https://lovi.care/skincare/fr/p/clarins/purifying-toning-lotion/for/combination-skin) — Average fit — [€18.90 at Notino](https://www.notino.fr/clarins/cleansing-purifying-toning-lotion-lotion-tonique-douce-pour-peaux-mixtes-a-grasses/p-16229346/) — Evening
- Serum or Treatment: [BRIGHT PLUS](https://lovi.care/skincare/fr/p/clarins/bright-plus/for/combination-skin) — Low fit — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/fr/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — [€49.00 at Amazon](https://www.amazon.fr/dp/B0D1YJN279?tag=lovi-care-web-routine05-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask](https://lovi.care/skincare/fr/p/herbivore-botanicals/blue-tansy-bha-and-enzyme-pore-refining-mask/for/combination-skin) — Superior fit — [€79.97 at Amazon](https://www.amazon.fr/dp/B015RRNQCY?tag=lovi-care-web-routine05-21&linkCode=osi&th=1&psc=1) — Once a week

[See multi-brand routine · 96% fit](https://lovi.care/skincare/fr/skin/combination-skin)

## Questions and answers

### La Roche-Posay or Clarins: which is better?

Both brands offer an equal routine fit across all skin types on the products on this page, but they differ in formulations and feedback. La Roche-Posay is generally better for sensitive skin and value, while Clarins is often noted for texture, brightening, and luxury. [Niacinamide](https://lovi.care/skincare/fr/ingredients/niacinamide) helps control skin aging and pigmentation.

[The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/) [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### What is the difference between La Roche-Posay and Clarins?

La Roche-Posay and Clarins are both French skincare brands founded decades ago, but they differ in formulation approaches and user feedback on this page. La Roche-Posay tends to be gentler on sensitive skin and has more fragrance-free options, whereas Clarins is often noted for luxurious textures and glowing [serums](https://lovi.care/skincare/fr/ingredients/serum). Both brands achieve high routine fit levels across major skin types.

### La Roche-Posay or Clarins for dry skin?

Both brands are a good choice for dry skin, as Lovi rates the routine fit for dry skin as High for both La Roche-Posay and Clarins. La Roche-Posay features products like Pure [Vitamin C](https://lovi.care/skincare/fr/ingredients/vitamin-c) Cream which has a Superior fit for dry skin, while Clarins offers options like Hydra-Essentiel Silky Cream which also has a Superior fit for dry skin.

### La Roche-Posay or Clarins: which cleanser is better?

Both La Roche-Posay and Clarins offer effective cleansers on the products on this page, but La Roche-Posay tends to be gentler on sensitive skin. Reviewers note that La Roche-Posay has fewer fragrance and scent issues than Clarins.

### Which is more affordable, La Roche-Posay or Clarins?

La Roche-Posay is more affordable, as price and value concerns are often mentioned for Clarins and are a notable drawback on its page.

### Between La Roche-Posay and Clarins, which brand offers more fragrance-free products?

La Roche-Posay offers significantly more fragrance-free options, with 21 out of 35 products on this page listing no fragrance. In contrast, Clarins has only 1 fragrance-free product among the 24 listed on its page.

### How do La Roche-Posay and Clarins compare regarding brightening and dark spots according to review themes?

Clarins does better than La Roche-Posay regarding brightening and dark spots according to review themes. Both brands feature key ingredients like niacinamide and vitamin C that help improve skin appearance and reduce pigmentation.

[The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/) [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### Which brand is better for sensitive skin regarding fragrance and scent issues?

La Roche-Posay is better for sensitive skin regarding fragrance and scent issues, as 21 of the products on this page list no fragrance compared to only 1 for Clarins. Reviewers also note that strong fragrance and scent issues are less of a concern for La Roche-Posay.

### La Roche-Posay or Clarins for oily skin?

Both La Roche-Posay and Clarins offer products that are well-suited for oily skin, with both brands achieving a High routine fit level for this skin type. La Roche-Posay features options like the Anthelios sunscreen which has a Superior fit level for oily skin, while Clarins provides choices such as the Double Serum Light Texture.

### La Roche-Posay or Clarins: which moisturizer is better?

Both brands offer moisturizers with a High or Superior Lovi fit depending on your skin type. La Roche-Posay moisturizers frequently feature hydrating and soothing key ingredients like [glycerin](https://lovi.care/skincare/fr/ingredients/glycerin), niacinamide, and [hyaluronic acid](https://lovi.care/skincare/fr/ingredients/hyaluronic-acid), whereas Clarins formulas often incorporate [shea butter](https://lovi.care/skincare/fr/ingredients/shea-butter) and squalane.

[The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/) [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### La Roche-Posay or Clarins for sensitive skin?

Both La Roche-Posay and Clarins offer options that fit sensitive skin well, as the products on this page show high routine fit levels for both brands. However, reviewers note that La Roche-Posay does better when it comes to being gentle on sensitive skin.

### La Roche-Posay or Clarins for acne-prone skin?

Both brands offer an equal routine fit level of High for acne-prone skin. La Roche-Posay includes many fragrance-free options across the products on this page, whereas almost all Clarins products list fragrance.

## Research behind their key ingredients

- [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002
- [The Effect of Aloe Vera Clinical Trials on Prevention and Healing of Skin Wound: A Systematic Review](https://pubmed.ncbi.nlm.nih.gov/30666070/) Aloe barbadensis leaf juice · Iranian Journal of Medical Sciences, 2019
- [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007
- [Regulatory effects of Lactobacillus plantarum-GMNL6 on human skin health by improving skin microbiome](https://pubmed.ncbi.nlm.nih.gov/33526970/) Lactobacillus · International Journal of Medical Sciences, 2021
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Ascorbic acid, Tocopherol · Journal of Cosmetic Dermatology, 2020
- [Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/27261203/) Retinol · International Journal of Cosmetic Science, 2017
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Retinol · The British Journal of Dermatology, 2019
- [Vesicular carriers containing phenylethyl resorcinol for topical delivery system; liposomes, transfersomes and invasomes](https://pubmed.ncbi.nlm.nih.gov/32104421/) Phenylethyl resorcinol · Asian Journal of Pharmaceutical Sciences, 2018
- [Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo](https://pubmed.ncbi.nlm.nih.gov/19186973/) Acerola fruit extract, Ascorbyl glucoside · Journal of Periodontology, 2009
- [Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo](https://pubmed.ncbi.nlm.nih.gov/27279007/) Chamomile extracts · International Journal of Molecular Medicine, 2016
- [Moisturizing and Antiinflammatory Properties of Cosmetic Formulations Containing Centella asiatica Extract](https://pubmed.ncbi.nlm.nih.gov/27168678/) Madecassoside · Indian Journal of Pharmaceutical Sciences, 2016
- [Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin](https://pubmed.ncbi.nlm.nih.gov/33037252/) Squalane · Scientific Reports, 2020
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice · Clinical Pharmacology, 2018
- [Vitamin C mesotherapy versus topical application for gingival hyperpigmentation: a clinical and histopathological study](https://pubmed.ncbi.nlm.nih.gov/33966113/) Ascorbic acid · Clinical Oral Investigations, 2021
- [Ethosomes of Phenylethyl Resorcinol as Vesicular Delivery System for Skin Lightening Applications](https://pubmed.ncbi.nlm.nih.gov/28804723/) Phenylethyl resorcinol · BioMed Research International, 2017
- [Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate-irritated skin](https://pubmed.ncbi.nlm.nih.gov/18717861/) Ceramide-3, Ceramide np · International Journal of Dermatology, 2008
- [Effects of Locally Applied Glycerol and Xylitol on the Hydration, Barrier Function and Morphological Parameters of the Skin](https://pubmed.ncbi.nlm.nih.gov/27349297/) Xylitol · Acta Dermato-venereologica, 2017
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Ascorbic acid, Tocopherol · Journal of Cosmetic Dermatology, 2020
- [Efficacy of probiotic-derived lotion from Lactobacillus paracasei MSMC 39-1 in mild to moderate acne vulgaris, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/35384257/) Lactobacillus · Journal of Cosmetic Dermatology, 2022
- [Clinical, biometric and structural evaluation of the long-term effects of a topical treatment with ascorbic acid and madecassoside in photoaged human skin](https://pubmed.ncbi.nlm.nih.gov/18503551/) Centella asiatica leaf extract · Experimental Dermatology, 2008
- [Anti-inflammatory activities of colloidal oatmeal (Avena sativa) contribute to the effectiveness of oats in treatment of itch associated with dry, irritated skin](https://pubmed.ncbi.nlm.nih.gov/25607907/) Avena sativa kernel extract oat kernel extract · Journal of Drugs in Dermatology, 2015
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [The Effects of a Standardized Extract of Centella asiatica on Postlaser Resurfacing Wound Healing on the Face: A Split-Face, Double-Blind, Randomized, Placebo-Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/32310680/) Madecassoside · Journal of Alternative and Complementary Medicine, 2020
- [Prevention and Reduction of Atrophic Acne Scars with Adapalene 0.3%/Benzoyl Peroxide 2.5% Gel in Subjects with Moderate or Severe Facial Acne: Results of a 6-Month Randomized, Vehicle-Controlled Trial Using Intra-Individual Comparison](https://pubmed.ncbi.nlm.nih.gov/29549588/) Adapalene usp retinoid acne treatment, Adapalene · American Journal of Clinical Dermatology, 2018
- [Efficacy and Safety of a Fixed-Dose Clindamycin Phosphate 1.2%, Benzoyl Peroxide 3.1%, and Adapalene 0.15% Gel for Moderate-to-Severe Acne: A Randomized Phase II Study of the First Triple-Combination Drug](https://pubmed.ncbi.nlm.nih.gov/34674160/) Adapalene, Adapalene usp retinoid acne treatment · American Journal of Clinical Dermatology, 2022
- [Two superior antioxidants: Ferulic acid and ascorbic acid in reducing signs of photoaging-A split-face comparative study](https://pubmed.ncbi.nlm.nih.gov/34877760/) Acerola fruit extract · Dermatologic Therapy, 2022
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Stable Ozonides with Vitamin E Acetate versus Corticosteroid in the Treatment of Lichen Sclerosus in Foreskin: Evaluation of Effects on Inflammation](https://pubmed.ncbi.nlm.nih.gov/30991399/) Tocopheryl acetate · Urologia Internationalis, 2019
- [Adenosine-loaded dissolving microneedle patches to improve skin wrinkles, dermal density, elasticity and hydration](https://pubmed.ncbi.nlm.nih.gov/29574973/) Adenosine · International Journal of Cosmetic Science, 2018
- [A topical gel of tea tree oil nanoemulsion containing adapalene versus adapalene marketed gel in patients with acne vulgaris: a randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/34251536/) Adapalene, Adapalene usp retinoid acne treatment · Archives of Dermatological Research, 2022
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Panthenol, Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Gluconolactone · Clinical, Cosmetic and Investigational Dermatology, 2019
- [Mechanism of action and clinical benefits of colloidal oatmeal for dermatologic practice](https://pubmed.ncbi.nlm.nih.gov/20865844/) Avena sativa kernel extract · Journal of Drugs in Dermatology, 2010
- [High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin](https://pubmed.ncbi.nlm.nih.gov/11684194/) Witch hazel leaf extract · Phytochemistry, 2001
- [Systematic Study of Paeonol/Madecassoside Co-Delivery Nanoemulsion Transdermal Delivery System for Enhancing Barrier Repair and Anti-Inflammatory Efficacy](https://pubmed.ncbi.nlm.nih.gov/37446936/) Centella asiatica leaf extract, Madecassoside · Molecules, 2023
- [A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne](https://pubmed.ncbi.nlm.nih.gov/1303072/) Gluconolactone · The Australasian Journal of Dermatology, 1992
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [Biomimetic hyaluronic acid-stabilized zinc oxide nanoparticles in acne treatment: A preclinical and clinical approach](https://pubmed.ncbi.nlm.nih.gov/40254135/) Zinc · Journal of Controlled Release, 2025
- [Fatty acids based α-Tocopherol loaded nanostructured lipid carrier gel: In vitro and in vivo evaluation for moisturizing and anti-aging effects](https://pubmed.ncbi.nlm.nih.gov/32129554/) Vitamin e · Journal of Cosmetic Dermatology, 2020
- [A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid](https://pubmed.ncbi.nlm.nih.gov/34348350/) Ceramide-3, Ceramide np · Skin Pharmacology and Physiology, 2022
- [Clay jojoba oil facial mask for lesioned skin and mild acne--results of a prospective, observational pilot study](https://pubmed.ncbi.nlm.nih.gov/22585103/) Jojoba seed oil · Forschende Komplementarmedizin, 2012
- [Efficacy and Tolerability of a Skin Brightening/Anti-Aging Cosmeceutical Containing Retinol 0.5%, Niacinamide, Hexylresorcinol, and Resveratrol](https://pubmed.ncbi.nlm.nih.gov/27391637/) Hexylresorcinol · Journal of Drugs in Dermatology, 2016
- [Efficacy and safety of moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese versus 0.02% triamcinolone acetonide cream in decreasing adverse reaction and downtime after ablative fractional carbon dioxide laser resurfacing: A split-face, double-blinded, randomized, controlled trial](https://pubmed.ncbi.nlm.nih.gov/30945430/) Centella asiatica leaf extract · Journal of Cosmetic Dermatology, 2019
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Comparison of skin calming effects of cosmetic products containing 4-t-butylcyclohexanol or acetyl dipeptide-1 cetyl ester on capsaicin-induced facial stinging in volunteers with sensitive skin](https://pubmed.ncbi.nlm.nih.gov/26805418/) Neurosensine · Journal of the European Academy of Dermatology and Venereology, 2016
- [A dermocosmetic containing bakuchiol, Ginkgo biloba extract and mannitol improves the efficacy of adapalene in patients with acne vulgaris: result from a controlled randomized trial](https://pubmed.ncbi.nlm.nih.gov/25914553/) Ginkgo biloba extract · Clinical, Cosmetic and Investigational Dermatology, 2015
- [2-Mercaptonicotinoyl glycine prevents UV-induced skin darkening and delayed tanning in healthy subjects: A randomized controlled clinical study](https://pubmed.ncbi.nlm.nih.gov/38372022/) 2-mercaptonicotinoyl glycine · Journal of Cosmetic Dermatology, 2024
- [A Bayesian network meta-analysis of 14 molecules inhibiting UV daylight-induced pigmentation](https://pubmed.ncbi.nlm.nih.gov/38433524/) 2-mercaptonicotinoyl glycine · Journal of the European Academy of Dermatology and Venereology, 2024
- [Clindamycin phosphate 1.2%/adapalene 0.15%/benzoyl peroxide 3.1% gel for moderate-to-severe acne: Efficacy and safety results from two randomized phase 3 trials](https://pubmed.ncbi.nlm.nih.gov/37656094/) Adapalene · Journal of the American Academy of Dermatology, 2023
- [Colloidal Oatmeal <em>(Avena Sativa)</em> Improves Skin Barrier Through Multi-Therapy Activity](https://pubmed.ncbi.nlm.nih.gov/27272074/) Avena sativa kernel extract oat kernel extract · Journal of Drugs in Dermatology, 2016
- [Superior even skin tone and anti-ageing benefit of a combination of 4-hexylresorcinol and niacinamide](https://pubmed.ncbi.nlm.nih.gov/34958693/) Hexylresorcinol · International Journal of Cosmetic Science, 2022
- [Efficacy of a topical serum containing L-ascorbic acid, neohesperidin, pycnogenol, tocopherol, and hyaluronic acid in relation to skin aging signs](https://pubmed.ncbi.nlm.nih.gov/35150043/) Vitamin e · Journal of Cosmetic Dermatology, 2022
- [Efficacy and Tolerability of Topical Nicotinamide Plus Antibacterial Adhesive Agents and Zinc-Pyrrolidone Carboxylic Acid Versus Placebo as an Adjuvant Treatment for Moderate Acne Vulgaris in Indonesia: A Multicenter, Double-blind, Randomized, Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/32983333/) Zinc pca · The Journal of Clinical and Aesthetic Dermatology, 2020
- [Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/35775872/) Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022
- [Effects of 1,3-propanediol associated, or not, with butylene glycol and/or glycerol on skin hydration and skin barrier function](https://pubmed.ncbi.nlm.nih.gov/37699769/) Propanediol · International Journal of Cosmetic Science, 2024
- [Assessment of the Benefit of a Deep Cleansing Gel Containing Salicylic Acid 2%, Zinc Gluconate 0.2% and Lipohydroxy Acids 0.05% in Patients with Mild to Moderate Truncal Acne: Results from an Exploratory Study](https://pubmed.ncbi.nlm.nih.gov/36698447/) Zinc gluconate · Clinical, Cosmetic and Investigational Dermatology, 2023
- [Subclinical, non-erythematous irritation with an open assay model (washing): sodium lauryl sulfate (SLS) versus sodium laureth sulfate (SLES)](https://pubmed.ncbi.nlm.nih.gov/11278060/) Sodium laureth sulfate · Food and Chemical Toxicology, 2001
- [Topical application of jojoba (Simmondsia chinensis L.) wax enhances the synthesis of pro-collagen III and hyaluronic acid and reduces inflammation in the ex-vivo human skin organ culture model](https://pubmed.ncbi.nlm.nih.gov/38344180/) Jojoba seed oil · Frontiers in Pharmacology, 2024
- [Development of stable tocopherol succinate-loaded ethosomes to enhance transdermal permeation: In vitro and in vivo characterizations](https://pubmed.ncbi.nlm.nih.gov/35274433/) Vitamin e · Journal of Cosmetic Dermatology, 2022
- [Clinical evaluation of the efficacy of a facial serum containing dioic acid, glycolic acid, salicylic acid, LHA, citric acid, and HEPES in treating post-inflammatory hyperchromia and controlling oily skin in patients with acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/33617668/) Capryloyl salicylic acid, Citric acid · Journal of Cosmetic Dermatology, 2021
- [Amino acid complex (AAComplex) benefits in cosmetic products: In vitro and in vivo clinical studies](https://pubmed.ncbi.nlm.nih.gov/34694692/) Complex amino acid · Journal of Cosmetic Dermatology, 2022
- [In Vitro and Clinical Safety Assessment of the Multiple W/O/W Emulsion Based on the Active Ingredients from Rosmarinus officinalis L., Avena sativa L. and Linum usitatissimum L](https://pubmed.ncbi.nlm.nih.gov/34065623/) Avena sativa kernel extract oat kernel extract · Pharmaceutics, 2021
- [Whitening effect of alpha-bisabolol in Asian women subjects](https://pubmed.ncbi.nlm.nih.gov/20642768/) Bisabolol · International Journal of Cosmetic Science, 2010
- [Clinical tolerance and efficacy of capryloyl salicylic acid peel compared to a glycolic acid peel in subjects with fine lines/wrinkles and hyperpigmented skin](https://pubmed.ncbi.nlm.nih.gov/19146601/) Capryloyl salicylic acid · Journal of Cosmetic Dermatology, 2008
- [Comparative benefit of two thermal spring waters after photodynamic therapy procedure](https://pubmed.ncbi.nlm.nih.gov/17348993/) La roche-posay thermal spring water · Journal of Cosmetic Dermatology, 2007
- [Zinc(II) Complexes of Amino Acids as New Active Ingredients for Anti-Acne Dermatological Preparations](https://pubmed.ncbi.nlm.nih.gov/33561977/) Complex amino acid · International Journal of Molecular Sciences, 2021
- [In Vitro and Randomized, Double-Blind, Placebo-Controlled Trial to Determine the Efficacy and Safety of Nine Antiacne Medicinal Plants](https://pubmed.ncbi.nlm.nih.gov/32695206/) Saponaria officinalis leaf extract · Evidence-based Complementary and Alternative Medicine, 2020
- [Skin improvement and stability of Echinacea purpurea dermatological formulations](https://pubmed.ncbi.nlm.nih.gov/20384903/) Echinacea purpurea extract · International Journal of Cosmetic Science, 2010
- [Development of solid lipid microparticles (SLMs) containing asiatic acid for topical treatment of acne: Characterization, stability, in vitro and in vivo anti-acne assessment](https://pubmed.ncbi.nlm.nih.gov/38460769/) Centella asiatica leaf extract · International Journal of Pharmaceutics, 2024
- [Comprehensive assessment of the efficacy and safety of a clay mask in oily and acne skin](https://pubmed.ncbi.nlm.nih.gov/38009030/) Argilla · Skin Research and Technology, 2023
- [Squalane as a Promising Agent Protecting UV-Induced Inhibition of Collagen Biosynthesis and Wound Healing in Human Dermal Fibroblast](https://pubmed.ncbi.nlm.nih.gov/40363772/) Squalane · Molecules, 2025
- [The impacts of sodium lauroyl sarcosinate in facial cleanser on facial skin microbiome and lipidome](https://pubmed.ncbi.nlm.nih.gov/37990616/) Sodium lauroyl sarcosinate · Journal of Cosmetic Dermatology, 2024
- [Synergetic Effects of Aloe Vera Extract with Trimethylglycine for Targeted Aquaporin 3 Regulation and Long-Term Skin Hydration](https://pubmed.ncbi.nlm.nih.gov/38611819/) Betaine · Molecules, 2024
- [A dermocosmetic formulation containing Vichy volcanic mineralizing water, Vitreoscilla filiformis extract, niacinamide, hyaluronic acid, and vitamin E regenerates and repairs acutely stressed skin](https://pubmed.ncbi.nlm.nih.gov/34979590/) Vitreoscilla ferment · Journal of the European Academy of Dermatology and Venereology, 2022
- [Comparison of methods for assessing photoprotection against ultraviolet A in vivo](https://pubmed.ncbi.nlm.nih.gov/3819071/) Butyl methoxydibenzoylmethane · Journal of the American Academy of Dermatology, 1987
- [Using ordered mesoporous silica SBA-15 to limit cutaneous penetration and transdermal permeation of organic UV filters](https://pubmed.ncbi.nlm.nih.gov/31437563/) Butyl methoxydibenzoylmethane · International Journal of Pharmaceutics, 2019
- [Formulation of Ascorbic Acid and Betaine-based Therapeutic Deep Eutectic System for Enhanced Transdermal Delivery of Ascorbic Acid](https://pubmed.ncbi.nlm.nih.gov/38794349/) Betaine · Pharmaceutics, 2024
- [A controlled, three-part trial to investigate the barrier function and skin hydration properties of six skin protectants](https://pubmed.ncbi.nlm.nih.gov/16439809/) Dimethicone · Ostomy/wound Management, 2005
- [Enhancing Photoprotection and Mitigating Ex Vivo Stratum Corneum Oxidative Stress: A Multifunctional Strategy Combining Rosmarinic Acid with UVB Filters](https://pubmed.ncbi.nlm.nih.gov/40227214/) Octocrylene · Antioxidants, 2025
- [A randomized controlled trial to compare the effectiveness and safety of adsorbent lotion containing tapioca starch, spent grain wax, Butyrospermum parkii extract, argania spinosa kernel oil, aloe barbadensis, rosehip oil, and allantoin with a low-potency topical corticosteroid in the treatment of intertrigo](https://pubmed.ncbi.nlm.nih.gov/33811776/) Shea butter · Journal of Cosmetic Dermatology, 2022
- [Clinical efficacy and safety of nano-microneedle-assisted phenylethyl resorcinol for the treatment of infraorbital dark circles](https://pubmed.ncbi.nlm.nih.gov/32783330/) Phenylethyl resorcinol · Journal of Cosmetic Dermatology, 2021
- [Lactobionic acid in a natural alkylpolyglucoside-based vehicle: assessing safety and efficacy aspects in comparison to glycolic acid](https://pubmed.ncbi.nlm.nih.gov/20367666/) Pha polyhydroxy acid · Journal of Cosmetic Dermatology, 2010
- [Topical prevention from high energy visible light-induced pigmentation by 2-mercaptonicotinoyl glycine, but not by ascorbic acid antioxidant: 2 randomized controlled trials](https://pubmed.ncbi.nlm.nih.gov/41142247/) 2-mercaptonicotinoyl glycine · Frontiers in Pharmacology, 2025
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Nanowire-based squalene oleogel repairs skin photoaging](https://pubmed.ncbi.nlm.nih.gov/40001122/) Squalane · Journal of Nanobiotechnology, 2025
- [Why is sodium cocoyl isethionate (SCI) mild to the skin barrier? - An in vitro investigation based on the relative sizes of the SCI micelles and the skin aqueous pores](https://pubmed.ncbi.nlm.nih.gov/17598025/) Sodium cocoyl isethionate · Journal of Cosmetic Science, 2007
- [Emulgels Containing Perilla frutescens Seed Oil, Moringa oleifera Seed Oil, and Mixed Seed Oil: Microemulsion and Safety Assessment](https://pubmed.ncbi.nlm.nih.gov/35745923/) Moringa oleifera seed extract · Polymers, 2022
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025
- [A multicenter, double-blind study to evaluate the efficacy and safety of 2 treatments in participants with mild to moderate acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/22838094/) Micro-exfoliating lha · Cutis, 2012
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026
- [Propanediol (and) Caprylic Acid (and) Xylitol as a New Single Topical Active Ingredient against Acne: In Vitro and In Vivo Efficacy Assays](https://pubmed.ncbi.nlm.nih.gov/34771112/) Propanediol · Molecules, 2021
- [Modulating effects of oatmeal extracts in the sodium lauryl sulfate skin irritancy model](https://pubmed.ncbi.nlm.nih.gov/11867969/) Avena sativa kernel extract oat kernel extract · Skin Pharmacology and Applied Skin Physiology, 2002
- [Prospective, randomized, double-blind clinical study of split-body comparison of topical hydroquinone and hexylresorcinol for skin pigment appearance](https://pubmed.ncbi.nlm.nih.gov/36502500/) Hexylresorcinol · Archives of Dermatological Research, 2023
- [Combining Topical and Oral Botanicals for Skin Redness, Pigmentation, Sleep, and Mood: A Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/36431167/) Saffron extracts flower · Journal of Clinical Medicine, 2022
- [Moisturizing effect of stable cream containing Crocus sativus extracts](https://pubmed.ncbi.nlm.nih.gov/25362612/) Saffron extracts flower · Pakistan Journal of Pharmaceutical Sciences, 2014
- [Tocopherol succinate-loaded ethosomal gel synthesized by cold method technique: Deeper biophysical characterizations for translational application on human skin](https://pubmed.ncbi.nlm.nih.gov/38268219/) Vitamin e · Journal of Cosmetic Dermatology, 2024
- [Protective properties of Avène Thermal Spring Water on biomechanical, ultrastructural and clinical parameters of human skin](https://pubmed.ncbi.nlm.nih.gov/32870553/) Prebiotic thermal water, La roche-posay thermal spring water, Thermal spring water · Journal of the European Academy of Dermatology and Venereology, 2020
- [Comparison of clindamycin 1% and benzoyl peroxide 5% gel to a novel composition containing salicylic acid, capryloyl salicylic acid, HEPES, glycolic acid, citric acid, and dioic acid in the treatment of acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/23545907/) Capryloyl salicylic acid · Journal of Drugs in Dermatology, 2013
- [Histometric assessment of the age-related skin response to 2-hydroxy-5-octanoyl benzoic acid](https://pubmed.ncbi.nlm.nih.gov/9603669/) Capryloyl salicylic acid · Skin Pharmacology and Applied Skin Physiology, 1998
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery](https://pubmed.ncbi.nlm.nih.gov/36279763/) Hydrolyzed hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022
- [Evaulation of irritation potential of surfactant mixtures](https://pubmed.ncbi.nlm.nih.gov/18503452/) Sodium laureth sulfate · International Journal of Cosmetic Science, 1999
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Evaluation of additive effects of hydrolyzed jojoba (Simmondsia chinensis) esters and glycerol: a preliminary study](https://pubmed.ncbi.nlm.nih.gov/19146603/) Jojoba esters · Journal of Cosmetic Dermatology, 2008
- [A Double-Blind, 12-Week Study to Evaluate the Antiaging Efficacy of a Cream Containing the NFκB Inhibitor 4-Hexyl-1, 3-Phenylenediol and Ascorbic Acid-2 Glucoside in Adult Females](https://pubmed.ncbi.nlm.nih.gov/27272084/) Ascorbyl glucoside · Journal of Drugs in Dermatology, 2016
- [In vitro, ex vivo and clinical approaches to evaluate the potential effect of Gentiana lutea extract on skin](https://pubmed.ncbi.nlm.nih.gov/37365865/) Gentiana lutea extract · International Journal of Cosmetic Science, 2023
- [Lemon Balm (Melissa officinalis L.) Leaf Extract Promotes Endo180 Production in Dermal Fibroblasts and has Antiwrinkle Effect on Human Skin](https://pubmed.ncbi.nlm.nih.gov/39888701/) Melissa officinalis leaf extract · Photodermatology, Photoimmunology & Photomedicine, 2025
- [Impact of Hydrocolloid Dressing and Moisturizing Cream as Facial Skin Protectants Among Health Care Workers](https://pubmed.ncbi.nlm.nih.gov/38771104/) Dimethicone · Military Medicine, 2024
- [Effects of Malaysian thermal spring water as adjunct therapy for mild to moderate acne vulgaris - a prospective, randomised, controlled, split face study](https://pubmed.ncbi.nlm.nih.gov/38553920/) Prebiotic thermal water, La roche-posay thermal spring water, Thermal spring water, La roche-posay prebiotic thermal water, Thermal water · The Medical Journal of Malaysia, 2024
- [Efficacy and safety of a facial serum and a mask containing salicylic acid and lipohydroxy acid in acne management: A randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/36999489/) Micro-exfoliating lha · Journal of Cosmetic Dermatology, 2023
- [Facial disbiosis and UV filters](https://pubmed.ncbi.nlm.nih.gov/39499337/) Ethylhexyl salicylate · Archives of Dermatological Research, 2024
- [Rapid and Visible Efficacy of a Dermocosmetic in Acne Patients With Fair Skin Phototypes: Results of a Randomized Split-Face Study](https://pubmed.ncbi.nlm.nih.gov/41487026/) Zinc gluconate · Journal of Cosmetic Dermatology, 2026
- [A polyhydroxy acid skin care regimen provides antiaging effects comparable to an alpha-hydroxyacid regimen](https://pubmed.ncbi.nlm.nih.gov/15002657/) Pha polyhydroxy acid · Cutis, 2004
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [Topical application of retinyl propionate, 4 hexyl resorcinol, and niacinamide reverses molecular and clinical features of ageing](https://pubmed.ncbi.nlm.nih.gov/38685700/) Hexylresorcinol · International Journal of Cosmetic Science, 2024
- [Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos](https://pubmed.ncbi.nlm.nih.gov/39769217/) Ascorbyl glucoside · International Journal of Molecular Sciences, 2024
- [Cleansing lotion containing tamarind fruit pulp extract. II. Study of cumulative irritation effects in human](https://pubmed.ncbi.nlm.nih.gov/17760696/) Tamarindus indica pulp · Journal of Cosmetic Dermatology, 2007
- [Efficacy of a Topical Formulation on Skin Hydration and Barrier Function in Individuals With Xerosis: A 28-Day Randomized, Split-Leg, Untreated-Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/42108609/) Dipotassium glycyrrhizate · Journal of Cosmetic Dermatology, 2026
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Butyrospermum parkii butter shea butter, Saccharide isomerate, Shea butter · Lasers in Medical Science, 2025
- [Retrospective Review of Dermal Safety Studies of Organic Sunscreens](https://pubmed.ncbi.nlm.nih.gov/40911743/) Ethylhexyl salicylate, Homosalate · Journal of Drugs in Dermatology, 2025
- [Impact of dermal emulsions containing diacyl phospholipids, mono acyl phospholipids, sodium lauryl ether sulfate and polysorbate 80 in combination with UVA irradiation on human skin physiology in vivo: A pilot study](https://pubmed.ncbi.nlm.nih.gov/42617898/) Sodium laureth sulfate · International Journal of Pharmaceutics, 2026
- [Split-face evaluation: Gluconolactone plus oxybrasion versus gluconolactone plus microneedling. The effects on skin parameters](https://pubmed.ncbi.nlm.nih.gov/37357656/) Gluconolactone · Skin Research and Technology, 2023
- [Effects of an ultraviolet B radiation absorber on photocarcinogenesis in hairless albino mice](https://pubmed.ncbi.nlm.nih.gov/19365102/) Ethylhexyl triazone · Skin Pharmacology and Physiology, 2009
- [In vitro analysis of immunoprotective effects of topical sunscreens](https://pubmed.ncbi.nlm.nih.gov/20693002/) Ethylhexyl triazone · Toxicology in Vitro, 1994
- [Microcirculation-Promoting Effect of Escin on Cutaneous Tissue via Gsk3β Down-Regulation](https://pubmed.ncbi.nlm.nih.gov/41150788/) Escin · Current Issues in Molecular Biology, 2025
- [Microcirculatory efficacy of topical treatment with aescin + essential phospholipids gel in venous insufficiency and hypertension: new clinical observations](https://pubmed.ncbi.nlm.nih.gov/15156249/) Escin · Angiology, 2004
- [Phytochemical characterization and antidermatophytic activity of a leaf extract from Mitracarpusscaber](https://pubmed.ncbi.nlm.nih.gov/40945880/) Mitracarpus scaber extract · Journal of Ethnopharmacology, 2026
- [A novel facial moisturizer containing Saccharide isomerate accelerates skin barrier restoration following intense pulsed light treatment: a randomized split-face study](https://pubmed.ncbi.nlm.nih.gov/41211697/) Saccharide isomerate · The Journal of Dermatological Treatment, 2025
- [Saccharide isomerate ameliorates cosmetic scalp conditions in a Chinese study population](https://pubmed.ncbi.nlm.nih.gov/35279940/) Saccharide isomerate · Journal of Cosmetic Dermatology, 2023
- [Clinical Efficacy of Topical Ascorbic Acid 2-Glucoside in Enhancing Outcomes of Laser Gingival Depigmentation: A Randomized Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/42147661/) Ascorbyl glucoside · Cureus, 2026
- [Two new lipoaminoacids with complementary modes of action: new prospects to fight out against skin aging](https://pubmed.ncbi.nlm.nih.gov/19732187/) Palmitoyl glycine · International Journal of Cosmetic Science, 2010

## The brands

- French skincare: [La Roche-Posay](https://lovi.care/skincare/fr/brands/la-roche-posay)
- French skincare: [Clarins](https://lovi.care/skincare/fr/brands/clarins)

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- [The Ordinary vs La Roche-Posay](https://lovi.care/skincare/fr/compare/the-ordinary-vs-la-roche-posay)
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- [COSRX vs La Roche-Posay](https://lovi.care/skincare/fr/compare/cosrx-vs-la-roche-posay)
- [COSRX vs Clarins](https://lovi.care/skincare/fr/compare/cosrx-vs-clarins)
- [CeraVe vs La Roche-Posay](https://lovi.care/skincare/fr/compare/cerave-vs-la-roche-posay)
- [CeraVe vs Clarins](https://lovi.care/skincare/fr/compare/cerave-vs-clarins)
- [La Roche-Posay vs Dr. Althea](https://lovi.care/skincare/fr/compare/la-roche-posay-vs-dr-althea)
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- [La Roche-Posay vs Purito](https://lovi.care/skincare/fr/compare/la-roche-posay-vs-purito)
- [La Roche-Posay vs Cetaphil](https://lovi.care/skincare/fr/compare/la-roche-posay-vs-cetaphil)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

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- France: https://lovi.care/skincare/fr/compare/la-roche-posay-vs-clarins (this page)
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