# Clinique vs MAC

Page: https://lovi.care/skincare/fr/compare/clinique-vs-mac

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for France.

Clinique and MAC are Estée Lauder Companies Inc. brands that offer thoughtful moisturizers and makeup removers. The American skincare brand incorporates [hyaluronic acid](https://lovi.care/skincare/fr/ingredients/hyaluronic-acid), [glycerin](https://lovi.care/skincare/fr/ingredients/glycerin), and [caffeine](https://lovi.care/skincare/fr/ingredients/caffeine) for dry sensitive and oily skin, while the Canadian skincare brand uses balanced formulas for balanced skin. Both brands provide reliable daily care, yet Clinique addresses specific concerns with targeted ingredients like glycerin and hyaluronic acid, whereas MAC relies on gentle formulations for steady maintenance.

Clinique is an American skincare brand founded in 1968 and owned by The Estée Lauder Companies Inc..

[en.wikipedia.org](https://en.wikipedia.org/wiki/Clinique) [elcompanies.com](https://www.elcompanies.com/en/who-we-are/our-heritage) [businesswire.com](https://www.businesswire.com/news/home/20261019083802/en/The-Este-Lauder-Companies-Appoints-Krista-Lee-Berger-Senior-Vice-President-Global-Marketing-Clinique) [glossy.co](https://www.glossy.co/beauty/glossy-pop-newsletter-clinique-launches-first-ever-creator-led-campaign/)

MAC is a Canadian skincare brand founded in 1984 and owned by The Estée Lauder Companies Inc. since 1994.

[elcompanies.com](https://www.elcompanies.com/en-gb/our-brands/mac) [en.wikipedia.org](https://en.wikipedia.org/wiki/Est%C3%A9e_Lauder_Companies)

This page compares some of the most popular Clinique and MAC products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg4d44a5bdeb).

### Popular Clinique vs MAC products

#### MAC

- [Hyper Real Serumizer](https://lovi.care/skincare/fr/p/mac/hyper-real-serumizer/for/dry-sensitive-skin) — High fit — [€69.00 at Lookfantastic](https://www.lookfantastic.fr/p/mac-hyper-real-serumizertm-skin-balancing-hydration-serum-30ml/14194687/)
- [Mineralize Timecheck Lotion](https://lovi.care/skincare/fr/p/mac/mineralize-timecheck-lotion/for/dry-skin) — High fit
- [Hyper Real Fresh Canvas Cleansing Oil](https://lovi.care/skincare/fr/p/mac/hyper-real-fresh-canvas-cleansing-oil/for/dry-sensitive-skin) — High fit

#### Clinique

- [moisture surge](https://lovi.care/skincare/fr/p/clinique/moisture-surge/for/sensitive-skin) — High fit
- [Take The Day Off Cleansing Balm](https://lovi.care/skincare/fr/p/clinique/take-the-day-off-cleansing-balm/for/dry-skin) — Average fit — [€25.90 at Amazon](https://www.amazon.fr/dp/B07D5C86RX?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1)
- [Dramatically Different Moisturizing Lotion+](https://lovi.care/skincare/fr/p/clinique/dramatically-different-moisturizing-lotion/for/dry-skin) — Average fit — [€29.49 at Amazon](https://www.amazon.fr/dp/B00CVZ3NJ2?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1)
- [All About Eyes](https://lovi.care/skincare/fr/p/clinique/all-about-eyes/for/dry-skin) — High fit — [€35.99 at Amazon](https://www.amazon.fr/dp/B000OUTR32?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1)
- [Dramatically Different Moisturizing Gel](https://lovi.care/skincare/fr/p/clinique/dramatically-different-moisturizing-gel/for/oily-skin) — High fit — [€30.25 at Amazon](https://www.amazon.fr/dp/B003JRI3OG?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1)
- [Smart Clinical Repair Wrinkle Correcting Serum](https://lovi.care/skincare/fr/p/clinique/smart-clinical-repair-wrinkle-correcting-serum/for/mature-skin) — Average fit — [€87.95 at Amazon](https://www.amazon.fr/dp/B09FG8TJDD?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1)
- [Moisture Surge Overnight Mask](https://lovi.care/skincare/fr/p/clinique/moisture-surge-overnight-mask/for/dry-skin) — High fit — [€26.95 at Amazon](https://www.amazon.fr/dp/B00HSZRQQQ?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1)
- [Clarifying Lotion 2](https://lovi.care/skincare/fr/p/clinique/clarifying-lotion-2/for/oily-acne-prone-skin) — Average fit — [€47.15 at Amazon](https://www.amazon.fr/dp/B000H74MNW?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1)

## People Say

Clinique

MAC

- Lightweight and Fast-Absorbing Texture Mostly Mentioned Mostly Mentioned “absorbs quickly — MAC Hyper Real Serumizer” “Absorbs in a snap — MAC Mineralize Timecheck Lotion” “Emulsifies beautifully and rinses off without a greasy film. — MAC Hyper Real Fresh Canvas Cleansing Oil” “sinks in immediately — Clinique moisture surge”
- Makeup Primer and Base Compatibility Often Mentioned Mostly Mentioned “foundation glides on — MAC Hyper Real Serumizer” “Sits beautifully under makeup — MAC Mineralize Timecheck Lotion” “Reduces appearance of pores — MAC Mineralize Timecheck Lotion” “foundation glides on — Clinique moisture surge”
- Sensitive Skin Care and Gentle Formula Mostly Mentioned Often Mentioned “never irritated my eyes — Clinique All About Eyes” “No stinging eyes — Clinique Take The Day Off Cleansing Balm” “cools the heat in my cheeks — Clinique Redness Solutions Daily Relief Cream” “Does not cause breakouts — MAC Mineralize Timecheck Lotion”
- Effective Hydration and Moisture Often Mentioned Often Mentioned “Keeps my dry patches at bay all day — Clinique Dramatically Different Moisturizing Lotion+” “skin feels soft and smooth — Clinique Moisture Surge Overnight Mask” “Leaves skin feeling soft and supple, never tight. — MAC Hyper Real Fresh Canvas Cleansing Oil”
- Skin Plumping and Smoothing Often Mentioned Sometimes Noted “skin feels silky smooth — Clinique Smart Clinical Repair Wrinkle Correcting Serum” “glass skin look — Clinique moisture surge” “visibly plumped up — Clinique Smart Clinical Repair Wrinkle Correcting Serum” “petal-soft skin — MAC Hyper Real Serumizer”
- Makeup Melting and Removal Rarely Noted Often Mentioned “Removes waterproof mascara completely without needing a separate remover. — MAC Hyper Real Fresh Canvas Cleansing Oil” “Melts waterproof mascara — Clinique Take The Day Off Cleansing Balm”
- High Price and Value Issues Often Mentioned Mostly Mentioned “jar is too small for the cost — Clinique moisture surge” “quite pricey — Clinique Smart Clinical Repair Wrinkle Correcting Serum” “Expensive for cleanser — Clinique Take The Day Off Cleansing Balm” “too expensive — MAC Hyper Real Serumizer”
- Skin Breakouts and Irritation Often Mentioned Sometimes Noted “caused acne — MAC Hyper Real Serumizer” “Breaks me out, I got pimples from this. — MAC Hyper Real Fresh Canvas Cleansing Oil” “Stings if it accidentally gets into the eyes. — MAC Hyper Real Fresh Canvas Cleansing Oil” “Woke up with whiteheads on my chin — Clinique Dramatically Different Moisturizing Lotion+”
- Unpleasant Scent and Strong Fragrance Sometimes Noted Often Mentioned “Smells like nail polish remover — Clinique Clarifying Lotion 2” “Smells like old oil — Clinique Take The Day Off Cleansing Balm” “Has a weird plastic-like smell — Clinique Dramatically Different Moisturizing Lotion+” “scent is overpowering — MAC Hyper Real Serumizer”

## Questions and answers

### Clinique or MAC: which is better?

Clinique is better for sensitive skin care and gentle formulas, as every product on the page lists no fragrance and reviewers note its gentle cleansers, whereas MAC products on this page all contain fragrance and reviewers mention skin irritation.

### What is the difference between Clinique and MAC?

Clinique is better suited for sensitive skin care and gentle formulas, whereas MAC performs better for lightweight and fast-absorbing textures as well as makeup primer compatibility. Every product on the Clinique page lists no fragrance, while all MAC products on this page contain fragrance. Additionally, Clinique provides effective hydration with key ingredients like [hyaluronic acid](https://lovi.care/skincare/fr/ingredients/hyaluronic-acid), which helps improve skin quality.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Clinique or MAC: which moisturizer is better?

Clinique is better for targeted hydration and sensitive skin needs, as every product on its page lists no fragrance, whereas MAC moisturizers contain fragrance and may cause sensitivity.

### Which is more affordable, Clinique or MAC?

Both Clinique and MAC share the same drawback of a high price point according to reviewers on this page, meaning neither brand stands out as more affordable.

### Which causes fewer breakouts, Clinique or MAC?

Clinique is the better choice for avoiding breakouts, as MAC is more frequently linked in reviews to skin breakouts and irritation. Furthermore, Clinique has fragrance-free products on this page, whereas all MAC products on this page contain fragrance, which may help reduce skin sensitivity.

### Between Clinique and MAC, which brand offers fragrance-free products according to the page?

Clinique offers fragrance-free products on this page, as every product lists no fragrance in its ingredients, whereas MAC includes fragrance in all of its products.

### How do Clinique and MAC compare when it comes to sensitive skin care and gentle formulas?

For sensitive skin care and gentle formulas, Clinique does better than MAC. Every Clinique product on this page lists no fragrance in its ingredients, whereas all MAC products on this page contain fragrance.

### Which brand has products that receive positive reviews for being makeup bases and primers?

MAC receives positive reviews for its makeup bases and primers, whereas Clinique is sometimes noted for its makeup bases.

## Research behind their key ingredients

- [Biological and pharmacological activities of squalene and related compounds: potential uses in cosmetic dermatology](https://pubmed.ncbi.nlm.nih.gov/19169201/) Squalene · Molecules, 2009
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate · Dermatologic Therapy, 2022
- [Caffeine's mechanisms of action and its cosmetic use](https://pubmed.ncbi.nlm.nih.gov/23075568/) Caffeine · Skin Pharmacology and Physiology, 2013
- [Topical application of glycolic acid suppresses the UVB induced IL-6, IL-8, MCP-1 and COX-2 inflammation by modulating NF-κB signaling pathway in keratinocytes and mice skin](https://pubmed.ncbi.nlm.nih.gov/28330776/) Micro-acid complex · Journal of Dermatological Science, 2017
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Tocopherol · Journal of Cosmetic Dermatology, 2020
- [Protecting skin photoaging by NF-kappaB inhibitor](https://pubmed.ncbi.nlm.nih.gov/20540695/) Magnolia officinalis bark extract · Current Drug Metabolism, 2010
- [Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo](https://pubmed.ncbi.nlm.nih.gov/19186973/) Ascorbyl glucoside · Journal of Periodontology, 2009
- [Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin](https://pubmed.ncbi.nlm.nih.gov/33037252/) Squalane · Scientific Reports, 2020
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf water, Aloe barbadensis · Clinical Pharmacology, 2018
- [Urea: a comprehensive review of the clinical literature](https://pubmed.ncbi.nlm.nih.gov/24314769/) Urea · Dermatology Online Journal, 2013
- [Effect of Camellia japonica oil on human type I procollagen production and skin barrier function](https://pubmed.ncbi.nlm.nih.gov/17386986/) Camellia japonica seed oil · Journal of Ethnopharmacology, 2007
- [Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate-irritated skin](https://pubmed.ncbi.nlm.nih.gov/18717861/) Ceramide np · International Journal of Dermatology, 2008
- [Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls](https://pubmed.ncbi.nlm.nih.gov/18631247/) Camellia sinensis leaf extract · Experimental Dermatology, 2009
- [Effect of 30% Supramolecular Salicylic Acid Peel on Skin Microbiota and Inflammation in Patients with Moderate-to-Severe Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/36350527/) Micro-acid complex · Dermatology and Therapy, 2023
- [Systematic Study of Resveratrol Nanoliposomes Transdermal Delivery System for Enhancing Anti-Aging and Skin-Brightening Efficacy](https://pubmed.ncbi.nlm.nih.gov/36985709/) Polygonum cuspidatum root extract · Molecules, 2023
- [Role of Resveratrol in Regulating Cutaneous Functions](https://pubmed.ncbi.nlm.nih.gov/32382280/) Polygonum cuspidatum root extract · Evidence-based Complementary and Alternative Medicine, 2020
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/23417317/) Acetyl hexapeptide-8 · American Journal of Clinical Dermatology, 2013
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Stable Ozonides with Vitamin E Acetate versus Corticosteroid in the Treatment of Lichen Sclerosus in Foreskin: Evaluation of Effects on Inflammation](https://pubmed.ncbi.nlm.nih.gov/30991399/) Tocopheryl acetate · Urologia Internationalis, 2019
- [Magnolia ovovata extract and its active component magnolol prevent skin photoaging via inhibition of nuclear factor kappaB](https://pubmed.ncbi.nlm.nih.gov/17346696/) Magnolia officinalis bark extract · European Journal of Pharmacology, 2007
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Glycolic acid · Clinical, Cosmetic and Investigational Dermatology, 2019
- [High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin](https://pubmed.ncbi.nlm.nih.gov/11684194/) Witch hazel extract · Phytochemistry, 2001
- [Self-Assembled Cubic Liquid Crystalline Nanoparticles for Transdermal Delivery of Paeonol](https://pubmed.ncbi.nlm.nih.gov/26517086/) Paeonia albiflora flower extract · Medical Science Monitor, 2015
- [Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin](https://pubmed.ncbi.nlm.nih.gov/33911590/) Acetyl hexapeptide-8 · Annals of Dermatology, 2019
- [Efficacy of Probiotic Supplements and Topical Applications in the Treatment of Acne: A Scoping Review of Current Results](https://pubmed.ncbi.nlm.nih.gov/39810881/) Probiotic technology · Journal of Experimental Pharmacology, 2025
- [Systematic Study of Paeonol/Madecassoside Co-Delivery Nanoemulsion Transdermal Delivery System for Enhancing Barrier Repair and Anti-Inflammatory Efficacy](https://pubmed.ncbi.nlm.nih.gov/37446936/) Paeonia albiflora flower extract · Molecules, 2023
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [Clay jojoba oil facial mask for lesioned skin and mild acne--results of a prospective, observational pilot study](https://pubmed.ncbi.nlm.nih.gov/22585103/) Jojoba seed oil · Forschende Komplementarmedizin, 2012
- [A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid](https://pubmed.ncbi.nlm.nih.gov/34348350/) Ceramide np · Skin Pharmacology and Physiology, 2022
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Subclinical, non-erythematous irritation with an open assay model (washing): sodium lauryl sulfate (SLS) versus sodium laureth sulfate (SLES)](https://pubmed.ncbi.nlm.nih.gov/11278060/) Sodium laureth sulfate · Food and Chemical Toxicology, 2001
- [Topical application of jojoba (Simmondsia chinensis L.) wax enhances the synthesis of pro-collagen III and hyaluronic acid and reduces inflammation in the ex-vivo human skin organ culture model](https://pubmed.ncbi.nlm.nih.gov/38344180/) Jojoba seed oil · Frontiers in Pharmacology, 2024
- [Subclinical cutaneous inflammation remained after permeability barrier disruption enhances UV sensitivity by altering ER stress responses and topical pseudoceramide prevents them](https://pubmed.ncbi.nlm.nih.gov/28631090/) Ceramide ng · Archives of Dermatological Research, 2017
- [Safety assessment of cyclomethicone, cyclotetrasiloxane, cyclopentasiloxane, cyclohexasiloxane, and cycloheptasiloxane](https://pubmed.ncbi.nlm.nih.gov/22247236/) Cyclopentasiloxane · International Journal of Toxicology, 2011
- [The efficacy study of the combination of tripeptide-10-citrulline and acetyl hexapeptide-3. A prospective, randomized controlled study](https://pubmed.ncbi.nlm.nih.gov/28150423/) Acetyl hexapeptide-8 · Journal of Cosmetic Dermatology, 2017
- [Whitening effect of alpha-bisabolol in Asian women subjects](https://pubmed.ncbi.nlm.nih.gov/20642768/) Bisabolol · International Journal of Cosmetic Science, 2010
- [Antiacne and antiblotch activities of a formulated combination of Aloe barbadensis leaf powder, Garcinia mangostana peel extract, and Camellia sinensis leaf extract](https://pubmed.ncbi.nlm.nih.gov/31239743/) Camellia sinensis leaf extract · Clinical, Cosmetic and Investigational Dermatology, 2019
- [The synergistic effect of retinyl propionate and hydroxypinacolone retinoate on skin aging](https://pubmed.ncbi.nlm.nih.gov/36762391/) Hydroxypinacolone retinoate · Journal of Cosmetic Dermatology, 2023
- [Understanding Solar Skin Elastosis-Cause and Treatment](https://pubmed.ncbi.nlm.nih.gov/30052192/) Witch hazel extract · Journal of Cosmetic Science, 2018
- [Partially purified paeoniflorin exerts protective effects on UV-induced DNA damage and reduces facial wrinkles in human skin](https://pubmed.ncbi.nlm.nih.gov/16676123/) Paeonia albiflora flower extract · Journal of Cosmetic Science, 2006
- [Squalane as a Promising Agent Protecting UV-Induced Inhibition of Collagen Biosynthesis and Wound Healing in Human Dermal Fibroblast](https://pubmed.ncbi.nlm.nih.gov/40363772/) Squalane · Molecules, 2025
- [Epigallocatechin Gallate Enzymatic Alpha Glucosylation Potentiates Its Skin-Lightening Activity-Involvement of Skin Microbiota](https://pubmed.ncbi.nlm.nih.gov/39598779/) Camellia sinensis leaf extract · Molecules, 2024
- [Effects of Investigational Moisturizers on the Skin Barrier and Microbiome following Exposure to Environmental Aggressors: A Randomized Clinical Trial and Ex Vivo Analysis](https://pubmed.ncbi.nlm.nih.gov/37763018/) Yeast extract · Journal of Clinical Medicine, 2023
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Clinical efficacy and safety of nano-microneedle-assisted phenylethyl resorcinol for the treatment of infraorbital dark circles](https://pubmed.ncbi.nlm.nih.gov/32783330/) Dimethoxytolyl propylresorcinol · Journal of Cosmetic Dermatology, 2021
- [Synergistic action of a triple peptide complex on an essential extra-cellular matrix protein exhibits significant anti-aging benefits](https://pubmed.ncbi.nlm.nih.gov/20618556/) Multi-peptides · Journal of Cosmetic Dermatology, 2010
- [Algae extract protection effect on oxidized protein level in human stratum corneum](https://pubmed.ncbi.nlm.nih.gov/15247018/) Algae extract · Annals of the New York Academy of Sciences, 2004
- [Cucumber (Cucumis sativus L.) with heterologous poly-γ-glutamic acid has skin moisturizing, whitening and anti-wrinkle effects](https://pubmed.ncbi.nlm.nih.gov/38336313/) Cucumis sativus fruit extract · International Journal of Biological Macromolecules, 2024
- [Amended safety assessment of Sesamum indicum (sesame) seed oil, hydrogenated sesame seed oil, Sesamum indicum (sesame) oil unsaponifiables, and sodium sesameseedate](https://pubmed.ncbi.nlm.nih.gov/21772026/) Sesamum indicum oil · International Journal of Toxicology, 2011
- [The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects](https://pubmed.ncbi.nlm.nih.gov/23607739/) Acetyl hexapeptide-8 · Journal of Cosmetic and Laser Therapy, 2013
- [Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol](https://pubmed.ncbi.nlm.nih.gov/19514921/) Caprylyl glycol · Cutaneous and Ocular Toxicology, 2009
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [Functional properties and skin care effects of sodium trehalose sulfate](https://pubmed.ncbi.nlm.nih.gov/38606717/) Trehalose · Skin Research and Technology, 2024
- [A Double-Blind, 12-Week Study to Evaluate the Antiaging Efficacy of a Cream Containing the NFκB Inhibitor 4-Hexyl-1, 3-Phenylenediol and Ascorbic Acid-2 Glucoside in Adult Females](https://pubmed.ncbi.nlm.nih.gov/27272084/) Ascorbyl glucoside · Journal of Drugs in Dermatology, 2016
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Evaulation of irritation potential of surfactant mixtures](https://pubmed.ncbi.nlm.nih.gov/18503452/) Sodium laureth sulfate · International Journal of Cosmetic Science, 1999
- [Effects of a Postbiotic Saccharomyces and Lactobacillus Ferment Complex on the Scalp Microbiome of Chinese Women with Sensitive Scalp Syndrome](https://pubmed.ncbi.nlm.nih.gov/37767337/) Lactobacillus ferment · Clinical, Cosmetic and Investigational Dermatology, 2023
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [The efficacy of enoxolone in reducing erythema and pain after laser treatment: A randomized split-face pilot study](https://pubmed.ncbi.nlm.nih.gov/38622995/) Glycyrrhetinic acid · Journal of Cosmetic Dermatology, 2024
- [Efficacy of Topical Hydroxypinacolone Retinoate-Peptide Product Versus Fractional CO2 Laser in Facial Aging](https://pubmed.ncbi.nlm.nih.gov/39394831/) Hydroxypinacolone retinoate · Journal of Cosmetic Dermatology, 2025
- [Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos](https://pubmed.ncbi.nlm.nih.gov/39769217/) Ascorbyl glucoside · International Journal of Molecular Sciences, 2024
- [Impact of Hydrocolloid Dressing and Moisturizing Cream as Facial Skin Protectants Among Health Care Workers](https://pubmed.ncbi.nlm.nih.gov/38771104/) Dimethicone · Military Medicine, 2024
- [The effect of a serum containing acetyl hexapeptide-8, dipeptide diaminobutyroyl benzylamide diacetate and gluconolactone on skin biomarkers, wrinkles and skin texture: Ex vivo and clinical studies](https://pubmed.ncbi.nlm.nih.gov/41668671/) Laminaria digitata extract · International Journal of Cosmetic Science, 2026
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Butyrospermum parkii butter shea butter · Lasers in Medical Science, 2025
- [Clinical Efficacy of Topical Ascorbic Acid 2-Glucoside in Enhancing Outcomes of Laser Gingival Depigmentation: A Randomized Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/42147661/) Ascorbyl glucoside · Cureus, 2026
- [Impact of dermal emulsions containing diacyl phospholipids, mono acyl phospholipids, sodium lauryl ether sulfate and polysorbate 80 in combination with UVA irradiation on human skin physiology in vivo: A pilot study](https://pubmed.ncbi.nlm.nih.gov/42617898/) Sodium laureth sulfate · International Journal of Pharmaceutics, 2026
- [Simmondsia chinensis (jojoba) cake fermentation: A new, sustainable technology for advanced skin and scalp care ingredients](https://pubmed.ncbi.nlm.nih.gov/42698229/) Lactobacillus ferment · International Journal of Cosmetic Science, 2026
- [Efficacy of a Topical Formulation on Skin Hydration and Barrier Function in Individuals With Xerosis: A 28-Day Randomized, Split-Leg, Untreated-Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/42108609/) Dipotassium glycyrrhizate · Journal of Cosmetic Dermatology, 2026

## The brands

- American skincare: [Clinique](https://lovi.care/skincare/fr/brands/clinique)
- Canadian skincare: [MAC](https://lovi.care/skincare/fr/brands/mac)

## More comparisons

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- [SKIN1004 vs MAC](https://lovi.care/skincare/fr/compare/skin1004-vs-mac)
- [Anua vs Clinique](https://lovi.care/skincare/fr/compare/anua-vs-clinique)
- [Anua vs MAC](https://lovi.care/skincare/fr/compare/anua-vs-mac)
- [Medicube vs Clinique](https://lovi.care/skincare/fr/compare/medicube-vs-clinique)
- [Medicube vs MAC](https://lovi.care/skincare/fr/compare/medicube-vs-mac)
- [The Ordinary vs Clinique](https://lovi.care/skincare/fr/compare/the-ordinary-vs-clinique)
- [The Ordinary vs MAC](https://lovi.care/skincare/fr/compare/the-ordinary-vs-mac)
- [Beauty of Joseon vs Clinique](https://lovi.care/skincare/fr/compare/beauty-of-joseon-vs-clinique)
- [Beauty of Joseon vs MAC](https://lovi.care/skincare/fr/compare/beauty-of-joseon-vs-mac)
- [COSRX vs Clinique](https://lovi.care/skincare/fr/compare/cosrx-vs-clinique)
- [COSRX vs MAC](https://lovi.care/skincare/fr/compare/cosrx-vs-mac)
- [CeraVe vs Clinique](https://lovi.care/skincare/fr/compare/cerave-vs-clinique)
- [CeraVe vs MAC](https://lovi.care/skincare/fr/compare/cerave-vs-mac)
- [La Roche-Posay vs Clinique](https://lovi.care/skincare/fr/compare/la-roche-posay-vs-clinique)
- [La Roche-Posay vs MAC](https://lovi.care/skincare/fr/compare/la-roche-posay-vs-mac)
- [Dr. Althea vs Clinique](https://lovi.care/skincare/fr/compare/dr-althea-vs-clinique)
- [Dr. Althea vs MAC](https://lovi.care/skincare/fr/compare/dr-althea-vs-mac)
- [Some By Mi vs Clinique](https://lovi.care/skincare/fr/compare/some-by-mi-vs-clinique)
- [Some By Mi vs MAC](https://lovi.care/skincare/fr/compare/some-by-mi-vs-mac)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/clinique-vs-mac
- United Kingdom: https://lovi.care/skincare/uk/compare/clinique-vs-mac
- Ireland: https://lovi.care/skincare/ie/compare/clinique-vs-mac
- Germany: https://lovi.care/skincare/de/compare/clinique-vs-mac
- France: https://lovi.care/skincare/fr/compare/clinique-vs-mac (this page)
- Italy: https://lovi.care/skincare/it/compare/clinique-vs-mac
- Netherlands: https://lovi.care/skincare/nl/compare/clinique-vs-mac
- Spain: https://lovi.care/skincare/es/compare/clinique-vs-mac
- Canada: https://lovi.care/skincare/ca/compare/clinique-vs-mac
- Australia: https://lovi.care/skincare/au/compare/clinique-vs-mac
- Singapore: https://lovi.care/skincare/sg/compare/clinique-vs-mac
- Saudi Arabia: https://lovi.care/skincare/sa/compare/clinique-vs-mac
- United Arab Emirates: https://lovi.care/skincare/ae/compare/clinique-vs-mac