TULA 24-7 Moisture Hydrating Day & Night Cream for skin with dark spots

How to apply

Questions and answers

What the research says

• Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts.

  Molecules, 2025

• Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway.

  Antioxidants, 2025

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• Topical application of Bifida Ferment Lysate strengthens the skin barrier function by upregulating barrier and antimicrobial peptide genes, exhibiting strong antioxidant properties, and decreasing inflammatory cytokine secretion in vitro.

  Journal of Cosmetic Dermatology, 2023

Ingredients

Water, Butylene Glycol, Ethylhexyl Palmitate, Squalane, Glycerin, Caprylic Capric Triglyceride, Cetyl Alcohol, Dimethicone, Hydrogenated Oil, Glyceryl Stearate, Peg-100 Stearate, Bifida Lysate Ferment, Lactose, Lactis Proteinum Protéine Du Lait Milk Protein, Yogurt Extract, Hydrolyzed Rice Protein, Cichorium Intybus Root Extract, Blueberry Fruit Extract, Olus Huile Oil, Camelina Sativa Seed Oil, Camellia Sinensis Leaf Extract, Curcuma Longa Root Extract, Tocopheryl Acetate, Ascorbyl Palmitate, Carthamus Tinctorius Seed Oil, Olea Europaea Oil Fruit Olive Oil Fruit, Pyrus Malus Fruit Extract, Watermelon Fruit Extract, Lens Esculenta Fruit Extract, Sodium Lactate, Sodium Pca, Carbomer, Sodium Hydroxide, Pentylene Glycol, Caprylyl Glycol, Bulnesia Sarmientoi Oil Wood, Lemon Oil Fruit, Citrus Aurantium Dulcis Oil, Juniperus Mexicana Oil, Cananga Odorata Oil Flower, Ethylhexylglycerin, Stearyl Alcohol, Disodium Edta, Citric Acid, Sorbic Acid, Phenethyl Alcohol, Sodium Benzoate, Potassium Sorbate, Phenoxyethanol, Parfum, Alpha-Isomethyl Ionone, Butylphenyl Methylpropional, Linalool, Hexyl Cinnamal

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.