Theramid Copper Peptide for dry sensitive skin
Copper Tripeptide-1
Acetyl Tetrapeptide-2
Sodium Hyaluronate
Bifida Lysate Ferment
Acetyl Glutamine
Average
- HighDry Skin Fit
- AverageEffectiveness
- HighSafety
Works for dry sensitive skin; other serums fit it better.
This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate hydration and anti-aging benefits for your dry and sensitive skin, as glycerin and sodium hyaluronate provide humectant action and barrier repair, while copper tripeptide-1 and acetyl hexapeptide-1 work to minimize fine lines and wrinkles.
- The formula is safe for your dry and sensitive skin, as it lacks harsh ingredients that could cause irritation.
- While the product offers general skincare benefits, its primary focus on hydration and anti-aging may not fully address your specific concerns of dryness and flakiness.
How to apply
- Use this PM routine for your evening skincare. Start using the serum 3 times a week and increase to daily use if your skin feels comfortable.
- Apply the serum after cleansing and toner, but right before your moisturizer. This step locks in deep hydration for dry skin.
- Gently press 2-3 drops of the serum into your skin using your palms. Let it absorb completely for a minute ⏱ before applying your next product.
- Since your skin is sensitive, apply the serum on completely dry skin for better tolerance and less irritation.
- Avoid the sensitive eye area during application. Always do a patch test before your first use to ensure your skin reacts well.
People Say
★4.4Overall rating based on 100+ reviewsA lightweight, fast-absorbing texture is frequently praised, and a moderate number of users report a boost in skin radiance. Some users find the high silicone content problematic for layering and note that copper peptides require careful routine planning to avoid conflicts with other active ingredients.
Highlights
Improves firmness Often Mentioned
- “my skin feels incredibly fed and plump”
- “improving skin elasticity and firmness”
- “it felt bouncier and more lifted”
- “helps to improve signs of aging... firm, smooth, radiant, and younger-looking skin”
Lightweight, fast-absorbing Often Mentioned
- “the texture is a sophisticated, lightweight gel that absorbs almost instantly without leaving a sticky residue”
- “absorbs quickly, and doesn't leave any stickiness, which is a huge plus for those of us who prefer to layer products”
- “it feels better on my skin... soaks in much better”
- “light, gel-like consistency absorbs quickly without leaving a tacky residue”
Boosts radiance Sometimes Noted
- “instantly gives the skin a radiant glow and freshness”
- “my skin has gotten a lot brighter and a lot better”
- “helps my complexion look lively”
- “promote a more youthful glow”
Gentle, non-irritating Sometimes Noted
- “incredibly gentle... I experienced zero redness or irritation”
- “I experienced no redness or dryness, which is often a concern when introducing strong active ingredients”
- “perfect for beginners, sensitive skin”
Hard to combine Sometimes Noted
- “copper peptides are high maintenance... you really don't want to use it in with anything that has a low pH”
- “I wouldn't recommend using it together with Niactilen”
- “Do not use with other acids and retinol products”
High silicone content Rarely Noted
- “I don't like the fact that is has so much silicone in it”
- “makes it very difficult to rub on the skin, because it 'sticks' to first place you put it and doesn't blend well”
- “This broke me out on my face”
No visible results Rarely Noted
- “Nearly 2 months in, no result”
- “No Effect”
- “I have it, I can't say how effective it is”
Sources: lovi.care, peptides133.com, peptides136.com, peptides138.com, youtube.com, lyko.com, and more
Questions and answers
How well does Theramid Copper Peptide treatment work for dry sensitive skin?
Theramid Copper Peptide treatment works moderately well for dry sensitive skin by offering gentle hydration and anti-aging benefits, though it may not fully address severe dryness and flakiness. Treatments that fit this skin best need rich moisturizing ingredients for deep moisture retention, skin barrier support, ceramides, and vitamins to soothe and protect without irritation.
Which ingredients make this treatment a good fit for dry sensitive skin?
Glycerin and sodium hyaluronate make this treatment a good fit by helping to draw in moisture and soothe dry skin. This product needs ingredients like ceramides, richer moisturizers, and barrier-protecting components to deeply nourish dry skin, relieve flakiness, and prevent moisture loss.
What does Copper Tripeptide-1 do for dry sensitive skin?
Copper Tripeptide-1 helps calm irritation and protects dry sensitive skin from sun damage while smoothing out wrinkles and supporting a stronger skin barrier. This ingredient may also improve overall firmness and elasticity, though a product for this skin type also needs gentle, soothing hydrators like colloidal oatmeal or plant oils to keep the skin soft and comfortable.
Skin Research and Technology, 2026Journal of Biomaterials Science. Polymer Edition, 2008
What does Acetyl Tetrapeptide-2 do for dry sensitive skin?
Acetyl Tetrapeptide-2 helps firm and support skin structure, which may improve how resilient dry sensitive skin feels. This ingredient works by helping cells maintain better integrity, though very sensitive skin should introduce it slowly to watch for any irritation.
International Journal of Peptide Research and Therapeutics, 2018
Where does this treatment go in a skincare routine for dry sensitive skin?
This treatment goes in the evening routine after your soothing toner and before your moisturizer. Dry and sensitive skin of this type needs a richer product focused heavily on deep hydration and soothing ingredients to properly combat dryness and flakiness.
Can I use this treatment with retinol, and in what order?
You can use this treatment with retinol by applying the treatment first and following with your retinol at night. Because this product lacks harsh ingredients, it is unlikely to irritate your skin, but dry and sensitive skin needs products that also bring extra moisture and soothing ingredients to fully tackle dryness and flakiness.
How often should I use this treatment?
You can use this treatment in your evening routine, applying it after your cleanser and soothing toner and before your moisturizer. A product of this type needs richer hydrators and barrier-repairing ingredients to fully comfort dry and sensitive skin.
Can this treatment clog pores, cause breakouts or purging for dry sensitive skin?
This treatment is unlikely to clog pores or cause breakouts on dry sensitive skin, as it is safe and lacks harsh ingredients that could cause irritation. A product of this type needs rich moisturizing ingredients and barrier-supporting agents to properly soothe dryness and flakiness.
Is this treatment fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Topical copper tripeptide complex on CO2 laser-resurfaced skin caused no significant reduction in erythema or objective improvement in wrinkles compared to controls, but significantly increased patient satisfaction regarding overall skin quality.
Archives of Facial Plastic Surgery, 2006A novel regimen combining a hydroxy acid-based scrub and copper tripeptide serum significantly reduced adherent scalp flaking by 61.24%, increased hair density by 12.48%, increased hair thickness by 25.36%, and improved scalp skin hydration by 76.24% in adults with mild to moderate dandruff over 15 days.
Cureus, 2024The combination of Thermus thermophilus and Bacillus subtilis mixed-culture ferment extract and copper tripeptide-1 GHK-Cu reduced inflammatory cytokines, protected skin explants from UV-induced damage, and improved wrinkles and skin barrier conditions compared to individual components or controls.
Skin Research and Technology, 2026Treatment of immortalized human keratinocytes with Acetyl Tetrapeptide-2 increased cell stiffness across its concentration range, while Acetyl Hexapeptide-50 increased stiffness at 0.05 µg/ml but decreased it at 0.5 and 5 µg/ml compared to untreated controls.
International Journal of Peptide Research and Therapeutics, 2018Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019Topical application of Bifida Ferment Lysate strengthens the skin barrier function by upregulating barrier and antimicrobial peptide genes, exhibiting strong antioxidant properties, and decreasing inflammatory cytokine secretion in vitro.
Journal of Cosmetic Dermatology, 2023
Why other serums fit dry sensitive skin better
Tocopherol succinate-loaded ethosomal gel increased skin deposition, stability, moisture, and mechanical properties in 13 human subjects compared to a control gel over 12 weeks.
Journal of Cosmetic Dermatology, 2022In 50 participants with sensitive skin, a Ceramide NP C15-containing emollient improved skin barrier function with a significant reduction in transepidermal water loss and induced modest changes in skin microbiota compared to the vehicle.
Skin Pharmacology and Physiology, 2026Hydrogels containing vitamin E-loaded nanostructured lipid carriers exhibited better occlusive properties and long-lasting effects, while vitamin E-loaded nanoemulsions performed a faster skin hydration effect and were selected as more attractive for skin application.
Colloids and Surfaces. B, Biointerfaces, 2019
Ingredients
Water, Propanediol, Cyclopentasiloxane, Dimethicone, Betaine, Copper Tripeptide-1, Bifida Lysate Ferment, Cyclohexasiloxane, Glycerin, Sodium Chloride, Polyglyceryl-4 Isostearate, Sodium Hyaluronate, Acetyl Tetrapeptide-2, Trifluoroacetyl Tripeptide-2, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-11, Sh-Polypeptide-9, Acetyl Hexapeptide-1, Bacillus Folic Acid Extract Ferment Filtrate, Cetyl Peg Ppg-10 1 Dimethicone, Hexyl Laurate, Peg Ppg-18 18 Dimethicone, Lecithin, Acetyl Glutamine, Caprylyl Glycol, Butylene Glycol, Dextran, Disodium Edta, Acetic Acid, Lactic Acid, 1,2-Hexanediol, Sodium Benzoate, Phenoxyethanol
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
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PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
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Specialist dermatologist, MBBS, MD, IFAAD
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Dermatology MD
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Elina Nazarenko, MD
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Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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