# the SAEM Power Ampoule for dry sensitive skin

**Lovi Fit: High fit for dry sensitive skin.**
Dry Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/es/p/the-saem/power-ampoule/for/dry-sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Brand: the SAEM
Category: [Serums and treatments](https://lovi.care/skincare/es/best/serums)

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for dry sensitive skin; a few serums fit it even better.

## Why this fit

- Offers high suitability for your dry and sensitive skin, as Centella Asiatica Extract and Beta-Glucan provide soothing benefits while Glycerin and Sodium Hyaluronate offer essential hydration. The inclusion of niacinamide and adenosine further enhances skin texture and brightness, complementing your skin's needs.
- The formulation includes a blend of beneficial oils like Camellia Sinensis Seed Oil and Argania Spinosa Kernel Oil, which contribute to nourishing dry skin, though a richer emollient base could further improve suppleness.
- The product is safe for your skin, with no harsh ingredients and a focus on soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/es/p/the-saem/power-ampoule/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/es/p/the-saem/power-ampoule/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/es/p/the-saem/power-ampoule/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/es/p/the-saem/power-ampoule/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/es/p/the-saem/power-ampoule/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/es/p/the-saem/power-ampoule/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/es/p/the-saem/power-ampoule/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/es/p/the-saem/power-ampoule/for/dry-sensitive-skin): High (this page)
- [Oily acne-prone skin](https://lovi.care/skincare/es/p/the-saem/power-ampoule/for/oily-acne-prone-skin): Average

## Key ingredients

Niacinamide, Sodium Hyaluronate, Ceramide Np, Palmitoyl Pentapeptide-4, Centella Asiatica Extract

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Combined therapy using a topical hyaluronic acid-niacinamide-Matrixyl serum and a multimodal facial device decreased TruSkin age by five years and reduced wrinkles more effectively than the serum alone in a 41-year-old woman with moderate facial aging over 12 weeks. ([Cureus, 2026](https://pubmed.ncbi.nlm.nih.gov/42500768/))
- Emulsions containing ceramides 1 and 3 improved skin hydration and reduced transepidermal water loss in sodium lauryl sulfate-irritated skin of fifteen healthy Asian women compared to a control emulsion. ([International Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18717861/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))

## What reviewers say

The SAEM Power Ampoule line provides targeted solutions for various skin concerns. The Hydra and Vitamin versions are highly praised for delivering deep hydration and brightening effects, particularly beneficial for dry or dull skin. The Pore Tightening version is divisive; while some users with oily skin achieve a matte finish, a notable number report breakouts or no visible pore reduction. A common issue across all versions is a frequently malfunctioning dropper.

- Disliked: Defective dropper (mostly mentioned)
- Liked: Deep hydration (often mentioned)
- Liked: Fast absorption (often mentioned)
- Liked: Affordable price (sometimes noted)
- Liked: Brightening effect (sometimes noted)
- Disliked: Caused breakouts (sometimes noted)
- Disliked: Ineffective on pores (sometimes noted)
- Disliked: Sticky finish (rarely noted)

## How to apply

- Use this PM routine for your evening skincare. Start using the serum 3 times a week and increase to daily use if your skin feels comfortable.
- Apply the serum after cleansing and toner, but right before your moisturizer. This step locks in deep hydration for dry skin.
- Gently press 2-3 drops of the serum into your skin using your palms. Let it absorb completely for a minute ⏱ before applying your next product.
- Since your skin is sensitive, apply the serum on completely dry skin for better tolerance and less irritation.
- Avoid the sensitive eye area during application. Always do a patch test before your first use to ensure your skin reacts well.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes the SAEM Power Ampoule a great fit for dry sensitive skin?

This ampoule is a great fit because Centella asiatica extract and beta-glucan calm your skin, while glycerin and sodium hyaluronate bring much-needed moisture. Niacinamide and adenosine also help brighten and smooth your complexion, while nourishing oils keep dry areas comfortable and safe from irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Which ingredients make this serum a good fit for dry sensitive skin?

Centella asiatica extract and beta-glucan help calm dry sensitive skin, while glycerin and sodium hyaluronate bring essential moisture. Niacinamide and adenosine further improve skin texture, and nourishing plant oils support your skin barrier.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### What does Niacinamide do for dry sensitive skin?

Niacinamide helps dry sensitive skin by calming irritation and keeping moisture locked in so your face feels soft and smooth. It works to build up your skin barrier and calm redness while being very gentle and unlikely to cause irritation.
Sources: [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/), [International Journal of Pharmaceutics, 2013](https://pubmed.ncbi.nlm.nih.gov/23220080/)

### What does Hyaluronic Acid do for dry sensitive skin?

Hyaluronic acid is a great fit for dry, sensitive skin because it brings a large boost in hydration, making the skin feel soft and smooth while improving barrier function. It helps calm tightness and dryness, and is unlikely to cause irritation.
Sources: [Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/), [Dermatology and Therapy, 2021](https://pubmed.ncbi.nlm.nih.gov/34176098/)

### Where does this serum go in a skincare routine for dry sensitive skin?

This treatment goes in your evening routine, applied after your soothing toner and before your moisturizer. Putting it in the evening helps keep your skin safe around sun exposure, though some treatments like this may also be used in the morning or twice a day.

### Can I use this serum with retinol, and in what order?

You can use this treatment with retinol by applying the treatment first and following with your retinol at night, provided your skin is used to both. Because this product contains soothing ingredients like Centella Asiatica and hydrating components like glycerin, it is unlikely to irritate dry and sensitive skin when combined properly.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### How often should I use this serum?

You can use this treatment in the evening as part of your routine. It is a great fit for your dry sensitive skin, helping to calm and hydrate.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Cureus, 2026](https://pubmed.ncbi.nlm.nih.gov/42500768/)

### Can this serum clog pores, cause breakouts or purging for dry sensitive skin?

This treatment may cause breakouts for dry sensitive skin, as moderate complaints of breakouts are reported by reviewers. It is unlikely to cause purging since it does not contain exfoliating active ingredients.

### Is this serum fragrance-free and alcohol-free?

It has no fragrance and contains drying alcohol (ethanol).

## Alternatives for dry sensitive skin

- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/es/p/skinceuticals/c-e-ferulic/for/dry-sensitive-skin) — Superior fit — €169.99 at Amazon
- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/es/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/dry-sensitive-skin) — Superior fit — €57.00 at Amazon
- [Augustinus Bader The Serum](https://lovi.care/skincare/es/p/augustinus-bader/the-serum/for/dry-sensitive-skin) — Superior fit — €333.00 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/es/p/cerave/hydrating-facial-cleanser/for/dry-sensitive-skin) — Superior fit — €8.85 at Amazon
- Soothing Toner: [SKIN1004 Centella Asiatica Toning Toner](https://lovi.care/skincare/es/p/skin1004/centella-asiatica-toning-toner/for/dry-sensitive-skin) — Superior fit — €23.99 at Amazon
- Moisturizer with Sun Protection: [d'Alba UVessence Mild Waterfull Sun Cream SPF 50](https://lovi.care/skincare/es/p/d-alba/uvessence-mild-waterfull-sun-cream-spf-50/for/dry-sensitive-skin) — Superior fit — €16.99 at Amazon

## Where to buy

No store in Spain has a checked price for this product, so the page shows none.

## Ingredients

Water, Ethanol, Glycerin, Dipropylene Glycol, 1,2-Hexanediol, Niacinamide, Methyl Gluceth-20, Laminaria Japonica Extract, Eclipta Prostrata Leaf Extract, Coccinia Indica Fruit Extract, Eclipta Prostrata Extract, Melia Azadirachta Flower Extract, Melia Azadirachta Leaf Extract, Piper Methysticum Stem Extract Root Leaf, Acmella Oleracea Extract, Curcuma Longa Root Extract, Ocimum Sanctum Leaf Extract, Centella Asiatica Extract, Panax Ginseng Extract Berry, Corallina Officinalis Extract, Honey Extract, Monascus Extract, Hydrogenated Lecithin, Sodium Hyaluronate, Camellia Sinensis Seed Oil, Camellia Japonica Seed Oil, Argania Spinosa Kernel Oil, Olea Europaea Oil Fruit Olive Oil Fruit, Macadamia Ternifolia Seed Oil, Helianthus Annuus Seed Oil Sunflower Seed Oil, Jojoba Seed Oil, Ammonium Acryloyldimethyltaurate Vp Copolymer, Polyglyceryl-10 Laurate, Methylpropanediol, Ceramide Np, Sodium Citrate, Sucrose Distearate, Xanthan Gum, Citric Acid, Adenosine, Fructooligosaccharides, Disodium Edta, Beta-Glucan, Polyquaternium-51, Glyceryl Stearate, Butylene Glycol, Bifida Lysate Ferment, Panthenol, Hydrolyzed Hyaluronic Acid, Raffinose, Folic Acid, Cholesterol, Aureobasidium Pullulans Ferment, Tromethamine, Palmitoyl Pentapeptide-4, Nonapeptide-1, Acetyl Hexapeptide-8, Copper Tripeptide-1, Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Hexapeptide-9, Hydrogenated Polydecene, Polyglyceryl-10 Oleate, Hydroxyacetophenone, Ethylhexylglycerin, Caprylyl Glycol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/the-saem/power-ampoule/for/dry-sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/the-saem/power-ampoule/for/dry-sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/the-saem/power-ampoule/for/dry-sensitive-skin
- Germany: https://lovi.care/skincare/de/p/the-saem/power-ampoule/for/dry-sensitive-skin
- France: https://lovi.care/skincare/fr/p/the-saem/power-ampoule/for/dry-sensitive-skin
- Italy: https://lovi.care/skincare/it/p/the-saem/power-ampoule/for/dry-sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/the-saem/power-ampoule/for/dry-sensitive-skin
- Spain: https://lovi.care/skincare/es/p/the-saem/power-ampoule/for/dry-sensitive-skin (this page)
- Canada: https://lovi.care/skincare/ca/p/the-saem/power-ampoule/for/dry-sensitive-skin
- Australia: https://lovi.care/skincare/au/p/the-saem/power-ampoule/for/dry-sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/the-saem/power-ampoule/for/dry-sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/the-saem/power-ampoule/for/dry-sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/the-saem/power-ampoule/for/dry-sensitive-skin