# The Ordinary Matrixyl 10% + HA for sensitive skin

**Lovi Fit: High fit for sensitive skin.**
Normal Skin Fit: Superior · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/es/p/the-ordinary/matrixyl-10-ha/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Brand: [The Ordinary](https://lovi.care/skincare/es/brands/the-ordinary)
Category: [Serums and treatments](https://lovi.care/skincare/es/best/serums)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for sensitive skin; a few serums fit it even better.

## Why this fit

- Offers excellent plumping and fine line minimization for your normal skin, as Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7 support skin barrier function and reduce redness and irritation. Glycerin and Sodium Hyaluronate provide essential hydration, maintaining your skin's barrier function.
- The peptides in this formula are present in moderate concentrations, effectively addressing your concerns about redness and irritation.
- The safety profile is excellent, with no risks of irritation for your sensitive skin due to the absence of harsh ingredients and the presence of soothing components like Glycerin and Sodium Hyaluronate.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/es/p/the-ordinary/matrixyl-10-ha/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/es/p/the-ordinary/matrixyl-10-ha/for/dry-skin): Superior
- [Combination skin](https://lovi.care/skincare/es/p/the-ordinary/matrixyl-10-ha/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/es/p/the-ordinary/matrixyl-10-ha/for/sensitive-skin): High (this page)
- [Acne-prone skin](https://lovi.care/skincare/es/p/the-ordinary/matrixyl-10-ha/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/es/p/the-ordinary/matrixyl-10-ha/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/es/p/the-ordinary/matrixyl-10-ha/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/es/p/the-ordinary/matrixyl-10-ha/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/es/p/the-ordinary/matrixyl-10-ha/for/oily-acne-prone-skin): Average

## Key ingredients

Palmitoyl Pentapeptide-4, Sodium Hyaluronate, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7

## What the research says

- Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants. ([Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/))
- A multi-modal methodology combining MALDI-MSI, in vivo RCM, echography, and histology revealed age-related decreases in extracellular matrix and epidermal-dermal junction proteins and undulation depth, while a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 improved subepidermal low-echogenic band thickness, density, and extracellular matrix structure compared to placebo. ([Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Palmitoyl tetrapeptide-7, acetyl hexapeptide-8, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-10 significantly increased type III collagen levels in human dermal fibroblasts following UV exposure, with their combination demonstrating a greater effect in vitro and enhancing type I, III, and IV collagen levels in ex vivo skin tissues compared to individual components. ([International Journal of Cosmetic Science, 2026](https://pubmed.ncbi.nlm.nih.gov/42683869/))

## What reviewers say

Based on a very large amount of data, this serum is frequently praised for its immediate hydrating and plumping effects, with many users noting a visible reduction in fine lines and improved skin texture with consistent use. Some users experience a tacky finish, and a smaller number report breakouts or no visible anti-aging results.

- Liked: Plumps and hydrates (mostly mentioned)
- Liked: Great value (often mentioned)
- Liked: Reduces fine lines (often mentioned)
- Liked: Gentle formulation (sometimes noted)
- Liked: Silky texture (sometimes noted)
- Disliked: No visible results (sometimes noted)
- Disliked: Sticky finish (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Unpleasant scent (rarely noted)

## How to apply

- Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
- Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
- Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
- Always do a patch test before your first use and avoid getting the serum too close to your eyes .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes The Ordinary Matrixyl 10% + HA a great fit for sensitive skin?

This product is a great fit for sensitive skin because it uses soothing ingredients like glycerin and sodium hyaluronate alongside moderate levels of peptides to calm redness and irritation. Its safe formula lacks harsh ingredients, meaning it is unlikely to cause irritation while keeping your skin hydrated.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for sensitive skin?

This serum is a great fit for sensitive skin because it contains glycerin and sodium hyaluronate to keep your skin calm and hydrated, alongside gentle peptides that help soothe redness and irritation. These ingredients have an excellent safety profile, meaning they are unlikely to cause any irritation for your skin.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Palmitoyl Pentapeptide-4 do for sensitive skin?

Palmitoyl pentapeptide-4 is generally suitable for sensitive skin and helps smooth fine lines while supporting overall skin firmness. Because sensitive skin can easily react to active ingredients, a product of this type needs soothing components and a gentle formula to calm irritation while delivering anti-aging benefits.
Sources: [International Journal of Cosmetic Science, 2005](https://pubmed.ncbi.nlm.nih.gov/18492182/), [Acta Biomaterialia, 2025](https://pubmed.ncbi.nlm.nih.gov/39694719/)

### What does Hyaluronic Acid do for sensitive skin?

Hyaluronic acid helps calm and hydrate sensitive skin while supporting the skin barrier to keep it soft and comfortable. Clinical studies show it improves surface moisture and reduces dryness, roughness, and redness without irritation.
Sources: [Journal of Drugs in Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/41037531/), [Journal of Cosmetic Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29356277/)

### Where does it go in a skincare routine for sensitive skin?

This treatment goes in the evening routine after your toner and before your moisturizer. Using it at night is very safe and helps avoid any extra sensitivity from sun exposure.

### Can I use this serum with vitamin C, and in what order?

You can use this serum with vitamin C by applying the vitamin C first and following with this peptide formula. This combination helps smooth fine lines while providing great hydration and keeping your skin calm.
Sources: [Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### How often should I use it?

You can use this treatment in your evening routine for simplicity and extra safety around sun exposure. The moderate amounts of peptides and soothing ingredients like glycerin and sodium hyaluronate are very unlikely to cause irritation.
Sources: [Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can this serum clog pores, cause breakouts or purging for sensitive skin?

This serum is unlikely to cause breakouts for sensitive skin, as complaints about clogged pores and breakouts are very low. Its soothing ingredients like glycerin and sodium hyaluronate help maintain a calm, hydrated barrier without harsh additives.

### Is it fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for sensitive skin

- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/es/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/sensitive-skin) — Superior fit — €57.00 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/es/p/skinceuticals/c-e-ferulic/for/sensitive-skin) — High fit — €169.99 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/es/p/neogen-dermalogy/real-vitamin-c-serum/for/sensitive-skin) — High fit — €29.76 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/es/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — €39.80 at Amazon
- Soothing Toner: [SKIN1004 Centella Asiatica Toning Toner](https://lovi.care/skincare/es/p/skin1004/centella-asiatica-toning-toner/for/sensitive-skin) — Superior fit — €23.99 at Amazon
- Moisturizer with Sun Protection: [Bioderma Bioderma Photoderm Mineral SPF 50+](https://lovi.care/skincare/es/p/bioderma/photoderm-mineral-fluide-spf50/for/sensitive-skin) — Superior fit — €19.13 at Amazon

## Where to buy

- Lookfantastic: €11.96 (https://www.lookfantastic.es/p/the-ordinary-matrixyl-10-ha-high-strength-peptide-formulation-30ml/11363394/)
Prices checked 13 Oct 2026.

## Ingredients

Water, Glycerin, Butylene Glycol, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-38, Sodium Hyaluronate, Hydroxypropyl Cyclodextrin, Ppg-26-Buteth-26, Peg-40 Hydrogenated Castor Oil, Polyacrylate Crosspolymer-6, Trisodium Ethylenediamine Disuccinate, Carbomer, Polysorbate 20, Ethoxydiglycol, Phenoxyethanol, Chlorphenesin
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/the-ordinary/matrixyl-10-ha/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/the-ordinary/matrixyl-10-ha/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/the-ordinary/matrixyl-10-ha/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/the-ordinary/matrixyl-10-ha/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/the-ordinary/matrixyl-10-ha/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/the-ordinary/matrixyl-10-ha/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/the-ordinary/matrixyl-10-ha/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/the-ordinary/matrixyl-10-ha/for/sensitive-skin (this page)
- Canada: https://lovi.care/skincare/ca/p/the-ordinary/matrixyl-10-ha/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/the-ordinary/matrixyl-10-ha/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/the-ordinary/matrixyl-10-ha/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/the-ordinary/matrixyl-10-ha/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/the-ordinary/matrixyl-10-ha/for/sensitive-skin