# SVR Sebiaclear Serum for acne-prone skin

**Lovi Fit: Superior fit for acne-prone skin.**
Combination Skin Fit: Superior · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/es/p/svr/sebiaclear-serum/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Brand: [SVR](https://lovi.care/skincare/es/brands/svr)
Category: [Serums and treatments](https://lovi.care/skincare/es/best/serums)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best serums for acne-prone skin.

## Why this fit

- Offers excellent treatment for your acne-prone skin as gluconolactone and salicylic acid work synergistically to exfoliate and reduce blemishes, while niacinamide helps regulate oil production on your combination skin.
- The camellia japonica flower extract provides additional soothing benefits, enhancing the overall comfort and efficacy for your skin.
- The product is safe for your skin, with no risks of irritation due to the absence of harsh ingredients and the presence of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/es/p/svr/sebiaclear-serum/for/oily-skin): Superior
- [Dry skin](https://lovi.care/skincare/es/p/svr/sebiaclear-serum/for/dry-skin): Low
- [Combination skin](https://lovi.care/skincare/es/p/svr/sebiaclear-serum/for/combination-skin): Superior
- [Sensitive skin](https://lovi.care/skincare/es/p/svr/sebiaclear-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/es/p/svr/sebiaclear-serum/for/acne-prone-skin): Superior (this page)
- [Skin with dark spots](https://lovi.care/skincare/es/p/svr/sebiaclear-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/es/p/svr/sebiaclear-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/es/p/svr/sebiaclear-serum/for/dry-sensitive-skin): Caution
- [Oily acne-prone skin](https://lovi.care/skincare/es/p/svr/sebiaclear-serum/for/oily-acne-prone-skin): Superior

## Key ingredients

Gluconolactone, Niacinamide, Salicylic Acid, Camellia Japonica Flower Extract, Biosaccharide Gum-4

## What the research says

- Gluconolactone 14% solution significantly improved mild to moderate acne by reducing inflamed and non-inflamed lesions similarly to 5% benzoyl peroxide, but with fewer side-effects in 150 patients. ([The Australasian Journal of Dermatology, 1992](https://pubmed.ncbi.nlm.nih.gov/1303072/))
- Twice daily application of a multitargeted dermocosmetic cream provided comparable efficacy to benzoyl peroxide 5% gel in reducing inflammatory, non-inflammatory, and total lesions in 150 Caucasian subjects with mild-to-moderate acne over 56 days, while demonstrating superior skin tolerability. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/))
- The use of a salicylic acid-based dermocosmetic significantly reduces the needed quantity of benzoyl peroxide without impacting efficacy in mild to moderate acne, and as maintenance post-benzoyl peroxide allows a significant reduction of acne relapse compared to vehicle. ([Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/38051857/))
- Camellia japonica flower extract protects against urban air pollutant-induced skin damage by scavenging radicals, inhibiting ROS generation, reducing MMP-1 and lipid peroxidation, and increasing collagen synthesis in in vitro and ex vivo models. ([BMC Complementary and Alternative Medicine, 2019](https://pubmed.ncbi.nlm.nih.gov/30691451/))
- A moisturizer containing licochalcone A, 1,2-decanediol, L-carnitine, and salicylic acid significantly reduced noninflammatory, inflammatory, and total acne lesion counts compared to a vehicle control in Thai patients during a 12-week maintenance phase. ([BioMed Research International, 2020](https://pubmed.ncbi.nlm.nih.gov/33150170/))
- Glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene showed no hindrance compared to adapalene monotherapy and provided benefits in reducing complications in 25 subjects with mild-to-moderate acne vulgaris. ([Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30858720/))
- Gluconolactone and tartaric acid significantly lower transepidermal water loss and erythema after sodium lauryl sulphate challenge compared to vehicle, untreated control, and glycolic acid in healthy subjects. ([The British Journal of Dermatology, 1997](https://pubmed.ncbi.nlm.nih.gov/9470910/))
- A polyhydroxy acid skin care regimen provided antiaging benefits comparable to an alpha-hydroxyacid regimen while demonstrating enhanced mildness and better tolerance in subjects. ([Cutis, 2004](https://pubmed.ncbi.nlm.nih.gov/15002657/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Cryotherapy with liquid nitrogen achieved a higher cure rate (39%) than salicylic acid (24%) and a wait-and-see approach (16%) for cutaneous warts at 13 weeks in primary care patients. ([CMAJ, 2010](https://pubmed.ncbi.nlm.nih.gov/20837684/))
- Treatment with 2% supramolecular salicylic acid hydrogel resulted in a regression and markedly improvement rate of 51.01% compared to 43.10% for Adapaline gel in patients with mild to moderate facial acne vulgaris, showing no significant difference in efficacy. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590107/))
- Topical 5% benzoyl peroxide plus salicylic acid achieved the greatest lesion reduction at early 2 to 4 week time points compared to benzoyl peroxide, clindamycin, and combination benzoyl peroxide/clindamycin, while 5% benzoyl peroxide plus salicylic acid and combination benzoyl peroxide/clindamycin showed similar efficacy at 10 to 12 weeks in acne patients. ([Journal of the American Academy of Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/20488582/))
- Camellia oleifera Abel shell 1,3-butanediol extract decreased facial melanin levels by 59% from baseline at 6 weeks compared to a placebo group showing no effect in 30 female subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/31033161/))
- Camellia japonica oil activated the human COL1A2 promoter, induced type I procollagen synthesis, inhibited matrix metalloproteinase-1 activity, and reduced trans-epidermal water loss without inducing adverse reactions in human skin. ([Journal of Ethnopharmacology, 2007](https://pubmed.ncbi.nlm.nih.gov/17386986/))
- Camellia japonica placenta extract treatment upregulated hair growth marker genes in human follicle dermal papilla cells in vitro and improved scalp moisture, sebum, keratin, and erythema in 42 adult female participants in vivo. ([FEBS Open Bio, 2021](https://pubmed.ncbi.nlm.nih.gov/33410284/))

## What reviewers say

Based on a very large amount of data, this serum is highly effective for adult acne-prone skin, significantly clearing blemishes and fading post-acne marks. Users with oily and combination skin frequently report improved hydration and smoother texture. A moderate number of users appreciate its gentle feel, while a smaller portion of users with sensitive or dry skin mention mild initial stinging or drying effects, and some note the presence of added fragrance.

- Liked: Clears blemishes (mostly mentioned)
- Liked: Fades marks (often mentioned)
- Liked: Hydrating and smoothing (often mentioned)
- Liked: Gentle on skin (sometimes noted)
- Disliked: Added fragrance (sometimes noted)
- Disliked: Can be drying (rarely noted)
- Disliked: Initial stinging (rarely noted)

## How to apply

- Use your serum as part of your PM routine and start 3x/week before working up to daily use.
- Apply this treatment after cleansing and toner, and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the product on clean, dry skin to help manage your breakouts safely.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes SVR Sebiaclear Serum one of the best fits for acne-prone skin?

This serum is an excellent fit because gluconolactone and salicylic acid work together to clear blemishes while niacinamide keeps oil in check. Soothing ingredients like camellia japonica flower extract help keep your skin calm and comfortable.
Sources: [The Australasian Journal of Dermatology, 1992](https://pubmed.ncbi.nlm.nih.gov/1303072/), [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/)

### Which ingredients make this serum a good fit for acne-prone skin?

This serum is a great fit for your acne-prone skin because gluconolactone and salicylic acid work together to clear blemishes, while niacinamide helps keep your oil levels balanced. Soothing ingredients like camellia japonica flower extract also keep your skin comfortable and calm.
Sources: [The Australasian Journal of Dermatology, 1992](https://pubmed.ncbi.nlm.nih.gov/1303072/), [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/)

### What does Gluconolactone do for acne-prone skin?

Gluconolactone helps clear acne-prone skin by reducing both inflamed and non-inflamed blemishes. It is well tolerated and tends to cause fewer side effects than traditional treatments.
Sources: [The Australasian Journal of Dermatology, 1992](https://pubmed.ncbi.nlm.nih.gov/1303072/), [Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30858720/)

### What does Niacinamide do for acne-prone skin?

Niacinamide helps acne-prone skin by reducing both inflamed and uninflamed breakouts and calming redness. It is also very helpful for keeping oily skin balanced by cutting down on excess oil production, and it is well tolerated by most people.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38299457/), [Cureus, 2024](https://pubmed.ncbi.nlm.nih.gov/38725769/)

### Where does this serum go in a skincare routine for acne-prone skin?

This serum goes in the evening routine, as treatments fit best then for simplicity and safety around sun exposure. It is unlikely to irritate your skin due to the soothing ingredients included.

### Can I use it with retinol, and in what order?

You can use this treatment with retinol by applying it at different times or alternating days to keep your skin calm and smooth. This product is unlikely to cause irritation when combined thoughtfully, but introducing them slowly helps your skin adjust comfortably.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/), [American Family Physician, 2012](https://pubmed.ncbi.nlm.nih.gov/23062156/)

### How often should I use this serum?

Use this treatment serum in your evening routine, starting just once a week and slowly increasing the frequency if your skin handles it well. Gluconolactone and salicylic acid help clear blemishes while keeping irritation low, making it a great match for your acne-prone skin.
Sources: [The Australasian Journal of Dermatology, 1992](https://pubmed.ncbi.nlm.nih.gov/1303072/), [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/)

### Can it clog pores, cause breakouts or purging for acne-prone skin?

This product is unlikely to clog pores or cause breakouts on acne-prone skin. Its key ingredients like gluconolactone, salicylic acid, and niacinamide help clear blemishes and control oil, and it is safe for your skin with very low chances of irritation.
Sources: [The Australasian Journal of Dermatology, 1992](https://pubmed.ncbi.nlm.nih.gov/1303072/), [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetearyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for acne-prone skin

- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/es/p/skinceuticals/c-e-ferulic/for/acne-prone-skin) — Superior fit — €169.99 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/es/p/neogen-dermalogy/real-vitamin-c-serum/for/acne-prone-skin) — Superior fit — €29.76 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/es/p/skin1004/probio-cica-intensive-ampoule/for/acne-prone-skin) — High fit — €21.99 at Amazon

## Pairs well with

- Cleanser: [B.LAB Matcha Hydrating Foam Cleanser](https://lovi.care/skincare/es/p/b-lab/matcha-hydrating-foam-cleanser/for/acne-prone-skin) — Superior fit — €11.99 at Amazon
- Hydrating Toner: [Paula's Choice Resist Advanced Replenishing Toner](https://lovi.care/skincare/es/p/paula-s-choice/advanced-replenishing-toner/for/acne-prone-skin) — Superior fit — €34.00 at Amazon
- Moisturizer: [SKIN1004 Centella Cream](https://lovi.care/skincare/es/p/skin1004/centella-cream/for/acne-prone-skin) — Superior fit — €17.49 at Amazon

## Where to buy

- Amazon.de: €18.37 (https://www.amazon.de/dp/B07H6653QT?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
Prices checked 5 Nov 2026.

## Ingredients

Water, Gluconolactone, Methyl Methacrylate Crosspolymer, Dicaprylyl Carbonate, Niacinamide, Propanediol, Sodium Hydroxide, Dimethicone, Glycerin, Biosaccharide Gum-4, Camellia Japonica Flower Extract, Cetearyl Dimethicone Crosspolymer, Crithmum Maritimum Extract, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Sclerotium Gum, Salicylic Acid, Sodium Hyaluronate, Tocopherol, 1,2-Hexanediol, Caprylic Capric Triglyceride, Cetearyl Alcohol, Glyceryl Stearate, Hydrogenated Oil, Peg-100 Stearate, Coco-Glucoside
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/svr/sebiaclear-serum/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/svr/sebiaclear-serum/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/svr/sebiaclear-serum/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/svr/sebiaclear-serum/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/svr/sebiaclear-serum/for/acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/svr/sebiaclear-serum/for/acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/svr/sebiaclear-serum/for/acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/svr/sebiaclear-serum/for/acne-prone-skin (this page)
- Canada: https://lovi.care/skincare/ca/p/svr/sebiaclear-serum/for/acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/svr/sebiaclear-serum/for/acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/svr/sebiaclear-serum/for/acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/svr/sebiaclear-serum/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/svr/sebiaclear-serum/for/acne-prone-skin