SVR Sebiaclear Serum for acne-prone skin

How to apply

Questions and answers

What the research says

• Gluconolactone 14% solution significantly improved mild to moderate acne by reducing inflamed and non-inflamed lesions similarly to 5% benzoyl peroxide, but with fewer side-effects in 150 patients.

  The Australasian Journal of Dermatology, 1992

• Twice daily application of a multitargeted dermocosmetic cream provided comparable efficacy to benzoyl peroxide 5% gel in reducing inflammatory, non-inflammatory, and total lesions in 150 Caucasian subjects with mild-to-moderate acne over 56 days, while demonstrating superior skin tolerability.

  Journal of Cosmetic Dermatology, 2024

• The use of a salicylic acid-based dermocosmetic significantly reduces the needed quantity of benzoyl peroxide without impacting efficacy in mild to moderate acne, and as maintenance post-benzoyl peroxide allows a significant reduction of acne relapse compared to vehicle.

  Journal of Drugs in Dermatology, 2023

• Camellia japonica flower extract protects against urban air pollutant-induced skin damage by scavenging radicals, inhibiting ROS generation, reducing MMP-1 and lipid peroxidation, and increasing collagen synthesis in in vitro and ex vivo models.

  BMC Complementary and Alternative Medicine, 2019

• A moisturizer containing licochalcone A, 1,2-decanediol, L-carnitine, and salicylic acid significantly reduced noninflammatory, inflammatory, and total acne lesion counts compared to a vehicle control in Thai patients during a 12-week maintenance phase.

  BioMed Research International, 2020

• Glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene showed no hindrance compared to adapalene monotherapy and provided benefits in reducing complications in 25 subjects with mild-to-moderate acne vulgaris.

  Clinical, Cosmetic and Investigational Dermatology, 2019

• Gluconolactone and tartaric acid significantly lower transepidermal water loss and erythema after sodium lauryl sulphate challenge compared to vehicle, untreated control, and glycolic acid in healthy subjects.

  The British Journal of Dermatology, 1997

• A polyhydroxy acid skin care regimen provided antiaging benefits comparable to an alpha-hydroxyacid regimen while demonstrating enhanced mildness and better tolerance in subjects.

  Cutis, 2004

• Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.

  Journal of Cosmetic Dermatology, 2021

• Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.

  The Journal of Investigative Dermatology, 2008

• Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.

  Dermatologic Surgery, 2005

• Cryotherapy with liquid nitrogen achieved a higher cure rate (39%) than salicylic acid (24%) and a wait-and-see approach (16%) for cutaneous warts at 13 weeks in primary care patients.

  CMAJ, 2010

• Treatment with 2% supramolecular salicylic acid hydrogel resulted in a regression and markedly improvement rate of 51.01% compared to 43.10% for Adapaline gel in patients with mild to moderate facial acne vulgaris, showing no significant difference in efficacy.

  Journal of Cosmetic Dermatology, 2024

• Topical 5% benzoyl peroxide plus salicylic acid achieved the greatest lesion reduction at early 2 to 4 week time points compared to benzoyl peroxide, clindamycin, and combination benzoyl peroxide/clindamycin, while 5% benzoyl peroxide plus salicylic acid and combination benzoyl peroxide/clindamycin showed similar efficacy at 10 to 12 weeks in acne patients.

  Journal of the American Academy of Dermatology, 2010

• Camellia oleifera Abel shell 1,3-butanediol extract decreased facial melanin levels by 59% from baseline at 6 weeks compared to a placebo group showing no effect in 30 female subjects.

  Journal of Cosmetic Dermatology, 2019

• Camellia japonica oil activated the human COL1A2 promoter, induced type I procollagen synthesis, inhibited matrix metalloproteinase-1 activity, and reduced trans-epidermal water loss without inducing adverse reactions in human skin.

  Journal of Ethnopharmacology, 2007

• Camellia japonica placenta extract treatment upregulated hair growth marker genes in human follicle dermal papilla cells in vitro and improved scalp moisture, sebum, keratin, and erythema in 42 adult female participants in vivo.

  FEBS Open Bio, 2021

Ingredients

Water, Gluconolactone, Methyl Methacrylate Crosspolymer, Dicaprylyl Carbonate, Niacinamide, Propanediol, Sodium Hydroxide, Dimethicone, Glycerin, Biosaccharide Gum-4, Camellia Japonica Flower Extract, Cetearyl Dimethicone Crosspolymer, Crithmum Maritimum Extract, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Sclerotium Gum, Salicylic Acid, Sodium Hyaluronate, Tocopherol, 1,2-Hexanediol, Caprylic Capric Triglyceride, Cetearyl Alcohol, Glyceryl Stearate, Hydrogenated Oil, Peg-100 Stearate, Coco-Glucoside

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.