# SU:M37 Losec Summa Elixir Night Ampoule for combination skin

**Lovi Fit: Average fit for combination skin.**
Combination Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/es/p/su-m37/losec-summa-elixir-night-ampoule/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Brand: [SU:M37](https://lovi.care/skincare/es/brands/su-m37)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/es/best/moisturizers)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for combination skin; other moisturizers fit it better.

## Why this fit

- Offers excellent moisturizing treatment for your combination skin due to the presence of glycerin and propanediol, which hydrate and enhance barrier resilience. These humectants are beneficial for your skin's overall health, though they do not directly address your oily shine concerns.
- Panthenol further supports barrier function and provides soothing benefits, contributing to general skincare improvements without targeting oil control.
- The product is safe for your combination skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/es/p/su-m37/losec-summa-elixir-night-ampoule/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/es/p/su-m37/losec-summa-elixir-night-ampoule/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/es/p/su-m37/losec-summa-elixir-night-ampoule/for/combination-skin): Average (this page)
- [Sensitive skin](https://lovi.care/skincare/es/p/su-m37/losec-summa-elixir-night-ampoule/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/es/p/su-m37/losec-summa-elixir-night-ampoule/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/es/p/su-m37/losec-summa-elixir-night-ampoule/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/es/p/su-m37/losec-summa-elixir-night-ampoule/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/es/p/su-m37/losec-summa-elixir-night-ampoule/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/es/p/su-m37/losec-summa-elixir-night-ampoule/for/oily-acne-prone-skin): Average

## Key ingredients

Lactobacillus Soybean Extract Ferment, Panthenol, Gold, Wine Extract, Beta-Glucan

## What the research says

- Topical application of 1,3-propanediol at various concentrations, alone or combined with butylene glycol and/or glycerol, increased skin hydration and reduced trans epidermal water loss in 30 healthy female subjects over an 8-hour period, with the 15% concentration and the addition of glycerol providing greater benefits. ([International Journal of Cosmetic Science, 2024](https://pubmed.ncbi.nlm.nih.gov/37699769/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- ANT1 soybean extract cream ameliorated complications and enhanced skin recovery after Nd:YAG laser therapy in 45 Asian women, with higher concentrations significantly reducing wrinkles, spots, and pores compared to placebo. ([Annals of Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29369914/))
- Genistein and daidzein inhibited UVB-induced hydrogen peroxide production in keratinocytes acting as free radical scavengers with negligible skin disruption, whereas glycitein showed no protective activity. ([International Journal of Pharmaceutics, 2008](https://pubmed.ncbi.nlm.nih.gov/18761396/))
- A phytoestrogen-enriched cosmetic formulation containing biotransformed soybean extract increased collagen-I expression in fibroblast cells and skin explants in an estrogen receptor beta-dependent manner without harming skin microbiota. ([Brazilian Journal of Medical and Biological Research = Revista Brasileira de Pesquisas Medicas E Biologicas, 2023](https://pubmed.ncbi.nlm.nih.gov/37878883/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans. ([Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/))
- Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two. ([Auris, Nasus, Larynx, 2020](https://pubmed.ncbi.nlm.nih.gov/32067777/))
- Topically delivered gold-coated silica microparticles combined with laser pulses reduced inflammatory lesions compared with sham treatments in patients with moderate-to-severe facial acne. ([The Journal of Investigative Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25748556/))
- Laser-activated gold microparticles combined with topical retinoids reduced inflammatory lesion counts by 68% at month 12 in 52 patients with mild-to-moderate inflammatory facial acne. ([Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37943275/))
- Combined treatment with a micro-diamond and micro-gold topical serum and a 1064 nm picosecond Nd:YAG laser produced moderate clinical improvement and high participant satisfaction in 40% of participants for facial skin rejuvenation with minimal side effects. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/35304935/))
- Treatment with Jacquez grapes wine extract protected a three-dimensional tissue culture model of human epidermis against UVB-induced oxidative damage by preventing ROS-mediated alterations. ([Toxicology in Vitro, 2006](https://pubmed.ncbi.nlm.nih.gov/16901675/))
- The V. vinifera skin extract (ACH37) scavenged reactive oxygen species, prevented inflammation, modulated extracellular matrix remodeling, increased telomere length and telomerase activity, and reversed UV-induced gene suppression in in vitro and ex vivo assays. ([Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37464908/))
- Skin care regimens containing beta-glucan improved hemoglobin index, skin hydration, and transepidermal water loss compared to vehicle control in 20 patients undergoing fractional laser therapy. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33128496/))
- Treatment with topical formulations containing beta-glucan combined with nanofractional radiofrequency plus magnetic nanofractional radiofrequency showed the best efficacy and was tolerable and effective in Chinese women with abdominal stretch marks compared to control groups. ([Dermatology and Therapy, 2023](https://pubmed.ncbi.nlm.nih.gov/37171578/))
- Topical beta-glucan mildly improved striae gravidarum, 1565-nm non-ablative fractional laser showed better results than topical beta-glucan, and the combined strategy further improved striae gravidarum atrophy compared to single treatment. ([The Journal of Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35570397/))

## Why other moisturizers fit combination skin better

- A peel-off facial mask containing myoinositol and trehalose-loaded liposomes improved adult female acne by decreasing lesion counts, sebum production, GAGS scores, and local androgen levels while increasing beclin-1 levels. ([Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28342238/))
- Gluconolactone chemical peels lower skin pH and transepidermal water loss while demonstrating seboregulatory properties in 16 female subjects. ([Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37335807/))

## What reviewers say

Based on limited data, this night ampoule is highly rated for providing intensive hydration and a radiant glow, particularly for dry or mature skin. Users appreciate its luxurious texture and skin barrier repair benefits. However, the high price point and the presence of essential oils and alcohol are noted concerns, with some experiencing a heavy finish or availability issues.

- Liked: Intensive hydration (mostly mentioned)
- Liked: Radiance and glow (often mentioned)
- Disliked: High price point (often mentioned)
- Liked: Luxurious texture (sometimes noted)
- Liked: Skin barrier repair (sometimes noted)
- Disliked: Availability issues (sometimes noted)
- Disliked: Potential irritants (sometimes noted)
- Disliked: Heavy/sticky finish (rarely noted)

## How to apply

- Use this moisturizer in your AM and PM routine every day to control shine. Always pair with SPF in the morning.
- Apply this moisturizer after your cleanser and toner, right before your morning SPF.
- Gently press a small amount of the moisturizer into your skin and avoid harsh rubbing. Let it ⏳absorb for a minute.
- Apply the moisturizer on slightly damp skin to help it lock in moisture better. This keeps your combination skin balanced.
- Avoid the eye area when applying the moisturizer. Do a patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does SU:M37 Losec Summa Elixir Night Ampoule work for combination skin?

This moisturizing treatment works well for combination skin by delivering effective hydration and soothing benefits, though it is unlikely to directly address oily shine concerns. A product of this type needs ingredients like ceramides, hyaluronic acid, niacinamide, and peptides to balance moisture while helping control oil.
Sources: [International Journal of Cosmetic Science, 2024](https://pubmed.ncbi.nlm.nih.gov/37699769/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Which ingredients make this ampoule a good fit for combination skin?

Glycerin, propanediol, and panthenol make this ampoule a good fit because they hydrate the skin and support its barrier function. To fit combination skin even better, a moisturizing treatment of this type needs ingredients like ceramides, hyaluronic acid, niacinamide, and peptides that also control oily shine.
Sources: [International Journal of Cosmetic Science, 2024](https://pubmed.ncbi.nlm.nih.gov/37699769/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### What does Lactobacillus Soybean Extract Ferment do for combination skin?

Lactobacillus Soybean Extract Ferment helps keep combination skin balanced and smooth. It works well within your routine to support a calm and healthy feel without making your skin oily.

### What does Panthenol do for combination skin?

Panthenol helps balance combination skin by boosting moisture while keeping redness and irritation calm. It is unlikely to cause breakouts and may help repair the skin barrier safely.
Sources: [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/), [Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29577586/)

### Where does this ampoule go in a skincare routine for combination skin?

This moisturizing treatment goes in the evening routine, after cleansing and before moisturizing, though some of them can also be used in the morning or twice a day. To properly care for combination skin, a product of this type needs to balance hydration with oil-control ingredients.

### Can I use this ampoule with retinol, and in what order?

You can use this moisturizing treatment with retinol by applying it before your retinol step to help support your skin barrier and calm irritation. To work best for combination skin, this type of product also needs oil-controlling ingredients.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use this ampoule?

This ampoule is used in the evening as a treatment step, applied after cleansing and toning and before your moisturizer. To fit combination skin better, a product of this type needs ingredients that help balance oil and control shine.

### Can this ampoule clog pores, cause breakouts or purging for combination skin?

This moisturizing treatment is unlikely to cause breakouts or clog pores on combination skin, as it is safe with no harsh or prohibited ingredients. To truly thrive, combination skin needs products that balance moisture while helping control oily shine.

### Can I use this ampoule around the eyes or on my body?

You can safely use this moisturizing treatment around the eyes and on the body because it has a gentle formula with no harsh ingredients. To properly care for combination skin, a product of this type needs lightweight hydrators and soothing agents like glycerin and panthenol alongside oil-controlling ingredients.
Sources: [International Journal of Cosmetic Science, 2024](https://pubmed.ncbi.nlm.nih.gov/37699769/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Is this ampoule fragrance-free and alcohol-free?

It has no fragrance and contains drying alcohol (alcohol denat).

## Alternatives for combination skin

- [MEDI-PEEL Peptide 9 Volume White Cica All-in-one Essence](https://lovi.care/skincare/es/p/medi-peel/peptide-9-volume-white-cica-all-in-one-essence/for/combination-skin) — High fit — €39.50 at Notino
- [MISSHA Super Aqua Ultra Hyalron Ampoule](https://lovi.care/skincare/es/p/missha/super-aqua-ultra-hyalron-ampoule/for/combination-skin) — Average fit — €20.00 at Notino

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/es/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — €39.80 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/es/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — €36.00 at Amazon
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/es/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/combination-skin) — Superior fit — €97.52 at Amazon

## Where to buy

No store in Spain has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, Propanediol, Alcohol Denat, 1,2-Hexanediol, Butylene Glycol, Lactobacillus Soybean Extract Ferment, Chondrus Crispus Extract, Bis-Peg-18 Methyl Ether Dimethyl Silane, Panthenol, Peg-40 Hydrogenated Castor Oil, Saccharomyces Barley Seed Ferment Filtrate, Saccharomyces Potato Extract Ferment Filtrate, Lauryl Dimethicone Polyglycerin-3 Crosspolymer, Polymethylsilsesquioxane, Tromethamine, Glyceryl Acrylate Acrylic Acid Copolymer, Wine Extract, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Carbomer, Polyquaternium-51, Gold, Euterpe Oleracea Fruit Extract, Vinegar, Bergamot Oil Fruit, Sodium Polyacrylate, Adenosine, Blueberry Fruit Extract, Lactobacillus Pear Juice Ferment Filtrate, Grapefruit Peel Oil, Lactobacillus Wasabia Japonica Extract Root Ferment, Saccharomyces Grape Extract Ferment, Lactobacillus Water Hyacinth Ferment, Lactobacillus Ginseng Root Ferment Filtrate, Lactobacillus Rye Flour Ferment, Saccharomyces Xylinum Black Tea Ferment, Monascus Rice Ferment, Trisodium Edta, Carthamus Tinctorius Flower Extract, Rosa Damascena Oil Flower, Phyllanthus Emblica Fruit Extract, Artemisia Annua Extract, Neem Leaf Extract, Beta-Glucan, Camellia Sinensis Leaf Extract, Elettaria Cardamomum Seed Oil, Cananga Odorata Oil Flower, Lavandula Angustifolia Oil Lavender Oil, Caprylic Capric Triglyceride, Pogostemon Cablin Oil, Salvia Officinalis Leaf Extract, Zingiber Officinale Root Extract, Clove Flower Extract, Yeast Extract Ferment, Lactobacillus Punica Granatum Extract Fruit Ferment, Diospyros Kaki Fruit Extract, Cucumis Sativus Fruit Extract, Melissa Officinalis Extract, Brassica Oleracea Capitata Leaf Extract, Rehmannia Glutinosa Root Extract, Morus Bombycis Leaf Extract, Ficus Carica Fruit Extract, Perilla Frutescens Leaf Extract, Geranium Robertianum Extract, Ipomoea Batatas Root Extract, Acorus Calamus Root Extract, Undaria Pinnatifida Extract, Pyrus Malus Fruit Extract, Leuconostoc Radish Root Extract, Fraxinus Excelsior Leaf Extract, Brassica Rapa Leaf Extract Turnip Leaf Extract, Rosmarinus Officinalis Leaf Extract Rosemary Leaf Extract, Nelumbo Nucifera Root Extract, Thymus Vulgaris Leaf Extract, Onion Bulb Extract, Portulaca Oleracea Extract, Glycyrrhiza Glabra Root Extract Licorice Root Extract, Codonopsis Lanceolata Root Extract, Ginkgo Biloba Nut Extract, Lavandula Angustifolia Flower Extract Lavender Flower Extract, Sesamum Indicum Seed Extract, Citrus Unshiu Peel Extract, Grifola Frondosa Fruiting Body Extract, Fennel Fruit Extract, Daucus Carota Sativa Root Extract Carrot Root Extract, Parsley Extract, Platycodon Grandiflorum Root Extract, Watermelon Fruit Extract, Lonicera Japonica Flower Extract Honeysuckle Flower Extract, Eriobotrya Japonica Leaf Extract, Houttuynia Cordata Extract, Ocimum Basilicum Leaf Extract, Artemisia Princeps Leaf Extract, Panicum Miliaceum Seed Extract, Sasa Veitchii Leaf Extract, Acer Palmatum Leaf Extract, Glechoma Hederacea Extract, Schizonepeta Tenuifolia Extract, Chamomilla Recutita Flower Extract Matricaria Flower Extract, Anemarrhena Asphodeloides Root Extract, Equisetum Arvense Extract, Spinach Leaf Extract, Cassia Obtusifolia Seed Extract, Centella Asiatica Extract, Dandelion Leaf Extract, Camellia Japonica Leaf Extract, Trichosanthes Kirilowii Root Extract, Lycium Chinense Fruit Extract, Allium Sativum Bulb Extract, Illicium Verum Fruit Extract Anise Fruit Extract, Prunus Armeniaca Fruit Extract Apricot Fruit Extract, Citrus Junos Fruit Extract, Beta Vulgaris Root Extract, Musa Sapientum Fruit Extract, Rubus Idaeus Fruit Extract Raspberry Fruit Extract, Carica Papaya Fruit Extract, Phaseolus Angularis Seed Extract, Hemerocallis Fulva Flower Extract, Hypericum Perforatum Stem Extract Flower Leaf, Curcuma Longa Root Extract, Coriandrum Sativum Leaf Extract Fruit, Helianthus Annuus Seed Extract Sunflower Seed Extract, Nigella Sativa Seed Extract, Lentinus Edodes Extract, Cymbopogon Citratus Extract, Plantago Major Seed Extract, Marrubium Vulgare Extract, Cichorium Intybus Root Extract, Prunus Persica Fruit Extract, Peppermint Stem Extract Flower Leaf, Chaenomeles Sinensis Fruit Extract, Bergamot Leaf Extract, Lippia Citriodora Leaf Extract, Akebia Quinata Extract, Crataegus Cuneata Fruit Extract, Actinidia Polygama Fruit Extract, Prunus Salicina Fruit Extract, Jasminum Sambac Flower Extract Jasmine Flower Extract, Citrus Aurantium Dulcis Oil Flower, Cinnamomum Zeylanicum Bark Extract, Valeriana Officinalis Root Extract Rhizome, Honey Extract, Boswellia Serrata Extract Resin
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/su-m37/losec-summa-elixir-night-ampoule/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/su-m37/losec-summa-elixir-night-ampoule/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/su-m37/losec-summa-elixir-night-ampoule/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/su-m37/losec-summa-elixir-night-ampoule/for/combination-skin
- France: https://lovi.care/skincare/fr/p/su-m37/losec-summa-elixir-night-ampoule/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/su-m37/losec-summa-elixir-night-ampoule/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/su-m37/losec-summa-elixir-night-ampoule/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/su-m37/losec-summa-elixir-night-ampoule/for/combination-skin (this page)
- Canada: https://lovi.care/skincare/ca/p/su-m37/losec-summa-elixir-night-ampoule/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/su-m37/losec-summa-elixir-night-ampoule/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/su-m37/losec-summa-elixir-night-ampoule/for/combination-skin
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