StriVectin AR™ Night Treatment for mature skin
Advanced Retinol
Sodium Hyaluronate
Peptides
Niacinamide
Vitamin EHigh
- HighNormal Skin Fit
- AverageEffectiveness
- HighSafety
A great choice for mature skin; a few serums fit it even better.
This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate benefits for your normal skin, as retinol and sodium hyaluronate work to minimize fine lines and wrinkles while providing hydration. Niacinamide further supports antioxidant activity and melanogenesis regulation, aligning with your goals.
- Glycerin and panthenol contribute to overall skin hydration and soothing, addressing your concerns for wrinkles and fine lines.
- The product is safe for your normal skin, with no identified risks of irritation due to the absence of harsh or prohibited ingredients.
How to apply
- Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
- Apply this serum after your toner and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- You can apply the serum on dry skin for the best results against fine lines.
- Always do a patch test before your first use and avoid the sensitive eye area.
People Say
★4.6Overall rating based on 1.3k+ reviewsBased on a very large amount of data, this retinol treatment is highly regarded by users, particularly those with mature and dry skin. It is frequently praised for its effectiveness in reducing fine lines and wrinkles, and for providing deep hydration without causing irritation. Many users report smoother, softer, and plumper skin by morning. Some users experience mild peeling or dryness, and a few mention an unpleasant scent or breakouts, but these are less common concerns.
Highlights
Deeply hydrating Often Mentioned
- “intense hydration”
- “skin feels moisturized, nourished”
- “hydrated very well”
- “rich creamy texture left my skin feeling great”
Reduces fine lines Often Mentioned
- “minimizing my fine lines”
- “fine lines are not as noticeable”
- “reduces the depth of wrinkles”
- “deeper lines have improved somewhat”
Gentle on skin Sometimes Noted
- “gentle enough to use every day”
- “doesn't cause me any irritation or redness”
- “no dry skin or peeling”
- “great retinol for sensitive skin”
Improves skin texture Sometimes Noted
- “smoother texture”
- “skin feels so soft and smooth”
- “refines texture and the look of pores”
- “rough texture has also improved”
Causes breakouts Rarely Noted
- “broke me out almost immediately”
- “caused some breakouts”
- “woke up with blemishes”
Causes peeling/dryness Rarely Noted
- “new formula is causing peeling or drying”
- “experienced slight irritation from the retinol”
- “can only use it a couple nights a week or peeling begins”
Greasy residue Rarely Noted
- “oily residue that never really absorbed”
- “way too heavy for me”
- “woke up feeling really greasy”
High price Rarely Noted
- “comes at a pretty steep price”
- “price is too high for the regular size”
- “wish it was more affordable”
Unpleasant scent Rarely Noted
- “could not get over the scent”
- “didn't love the color and scent”
- “has a noticeable fragrance”
Sources: lovi.care, macys.com, costco.com, dermstore.com, boots.com, lovelyskin.com, and more
Questions and answers
What makes StriVectin AR™ Night Treatment a great fit for mature skin?
This treatment is a great fit for mature skin because its advanced retinol, sodium hyaluronate, and niacinamide help smooth fine lines and wrinkles while keeping the skin hydrated. It also includes peptides, vitamin E, glycerin, and panthenol to soothe the skin and support a healthy, youthful look with a low risk of irritation.
Which ingredients make this treatment a good fit for mature skin?
Advanced Retinol, sodium hyaluronate, peptides, niacinamide, and vitamin E make this treatment a great fit for mature skin by helping minimize fine lines, smooth wrinkles, and boost hydration. Retinol helps improve skin firmness and texture, while niacinamide and hyaluronic acid support overall aging care.
What does Retinol do for mature skin?
Retinol helps smooth fine lines, keeps skin firm by boosting collagen, and gives mature skin a more even texture. It is unlikely to cause severe irritation when used properly, though it may occasionally lead to mild dryness or flaking.
What does Hyaluronic Acid do for mature skin?
Hyaluronic acid helps mature skin by deeply boosting moisture, improving elasticity, and smoothing the appearance of fine lines and wrinkles. Regular use keeps the skin looking plump and soft while supporting overall firmness and hydration.
Journal of Drugs in Dermatology, 2011Skin Research and Technology, 2024
Where does this treatment go in a skincare routine for mature skin?
This treatment goes in the evening routine after cleansing and toning, and before moisturizing. Putting treatments in the evening keeps things simple and provides extra safety around sun exposure.
Can I use this treatment with glycolic acid, and in what order?
It is best to use glycolic acid and this retinol treatment on alternating nights rather than together. Using strong acids and retinol at the same time may easily dry out your skin or cause irritation.
How often should I use this treatment?
Use this treatment in your evening routine as part of your nightly steps. It is a great fit for mature skin, helping to smooth fine lines while keeping your skin calm and hydrated with a low risk of irritation.
Can this treatment clog pores, cause breakouts or purging for mature skin?
This treatment is unlikely to clog pores or cause breakouts for mature skin, though retinol may sometimes cause mild peeling as your skin adjusts. Reviewers rarely report breakouts or peeling with this product.
Is this treatment fragrance-free and alcohol-free?
It has no drying alcohol and contains fragrance (parfum). Cetearyl alcohol is a fatty alcohol, which soften the skin.
What the research says
Treatment with a combination of niacinamide and hyaluronic acid improved skin aging signs and demonstrated a senomorphic effect by decreasing SASP and autocrine signaling genes in women.
Scientific Reports, 2024Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment.
American Journal of Clinical Dermatology, 2002Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle.
International Journal of Cosmetic Science, 2017Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging.
The British Journal of Dermatology, 2019Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity.
Journal of Controlled Release, 2018Topical stabilized retinol treatment induced HAS gene expression and increased hyaluronic acid production in human skin in vitro, ex vivo, and in vivo compared to vehicle.
Archives of Dermatological Research, 2017Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.
Journal of Cosmetic Dermatology, 2021Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.
The Journal of Investigative Dermatology, 2008Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.
Dermatologic Surgery, 2005Topical application of an antioxidant serum containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented particulate matter-induced degradation of extracellular matrix components, inflammation, and oxidative stress in the skin of 15 female volunteers compared to untreated controls.
Journal of Cosmetic Dermatology, 2025Dermatological products containing d-alpha tocopheryl acetate showed non-comedogenic potential with less than a 50% increase in microcomedones in 12 healthy male subjects compared to octyl palmitate.
Contemporary Clinical Trials Communications, 2021Topical application of an antioxidant mix containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented PM and UV-induced skin barrier perturbation, lipid peroxidation, inflammatory markers, MMP9 activation, and Type I collagen loss in 15 healthy females compared to untreated exposed skin.
Journal of Cosmetic Dermatology, 2024
Ingredients
Water, Glycerin, Dimethicone, Cetearyl Alcohol, Retinol, Sodium Hyaluronate, Niacinamide, Caprylic Capric Triglyceride, Butyrospermum Parkii Butter Shea Butter, Ceteareth-20, Glyceryl Stearate, Peg-100 Stearate, Phenoxyethanol, Ethylhexylglycerin, Tocopherol, Panthenol, Allantoin, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Disodium Edta, Parfum
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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