# SkinCeuticals Phloretin CF for oily acne-prone skin

**Lovi Fit: High fit for oily acne-prone skin.**
Oily Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/es/p/skinceuticals/phloretin-cf/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Brand: [SkinCeuticals](https://lovi.care/skincare/es/brands/skinceuticals)
Category: [Serums and treatments](https://lovi.care/skincare/es/best/serums)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for oily acne-prone skin; a few serums fit it even better.

## Why this fit

- Offers excellent antioxidant protection and brightening for your oily skin, as ascorbic acid and ferulic acid work to shield from pollution and even skin tone.
- The formula is highly suitable for your acne, blemishes, and breakouts, with ascorbic acid and phloretin aiding cell turnover and sebum regulation.
- The safety profile is excellent, with no risks of irritation for your oily skin due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/es/p/skinceuticals/phloretin-cf/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/es/p/skinceuticals/phloretin-cf/for/dry-skin): Caution
- [Combination skin](https://lovi.care/skincare/es/p/skinceuticals/phloretin-cf/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/es/p/skinceuticals/phloretin-cf/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/es/p/skinceuticals/phloretin-cf/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/es/p/skinceuticals/phloretin-cf/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/es/p/skinceuticals/phloretin-cf/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/es/p/skinceuticals/phloretin-cf/for/dry-sensitive-skin): Low
- [Oily acne-prone skin](https://lovi.care/skincare/es/p/skinceuticals/phloretin-cf/for/oily-acne-prone-skin): High (this page)

## Key ingredients

Phloretin, Ascorbic Acid, Ferulic Acid

## What the research says

- A topical antioxidant solution of 15% L-ascorbic acid, 1% alpha-tocopherol, and 0.5% ferulic acid provides significant photoprotection against solar-simulated UV radiation in human skin compared to its vehicle. ([Journal of the American Academy of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18603326/))
- A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/))
- Pretreatment with a topical antioxidant mixture of vitamin C, ferulic acid, and phloretin attenuated ultraviolet-induced sunburn cell formation, thymine dimer formation, matrix metalloproteinase-9 expression, p53 protein expression, and the suppression of CD1a-expressing Langerhans cells in human skin compared to vehicle control. ([Journal of Cosmetic Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/19146606/))
- Phloretin inhibits the growth of acne-related bacteria, attenuates P. acnes-induced inflammatory mediators in vitro, and significantly reduces comedo counts, sebum output, and porphyrin levels in subjects with whiteheads compared to before treatment. ([International Journal of Cosmetic Science, 2016](https://pubmed.ncbi.nlm.nih.gov/26212527/))
- Phloretin 3',3-disulfonate attenuated UVB-induced cyclobutane pyrimidine dimer formation, glutathione depletion, apoptosis, and inflammatory mediator release in skin cells by enhancing nucleotide excision repair gene expression. ([International Journal of Molecular Sciences, 2014](https://pubmed.ncbi.nlm.nih.gov/25334063/))
- Compound 11c showed potent inhibitory activity against tyrosinase at nanomolar concentrations and reduced melanin content in a UV-induced skin pigmentation guinea pig model. ([Journal of Medicinal Chemistry, 2023](https://pubmed.ncbi.nlm.nih.gov/36940414/))
- An optimized phloretin-based antiacne hydrogel formulation achieved 75% drug release over 120 minutes and strong antimicrobial activity against Staphylococcus epidermidis with an 11 mm inhibition zone, comparable to benzoyl peroxide gel, while showing no skin irritancy. ([Anti-inflammatory & Anti-allergy Agents in Medicinal Chemistry, 2026](https://pubmed.ncbi.nlm.nih.gov/42163615/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- Treatment with 14% ferulic acid and 12% l-ascorbic acid significantly reduced pigmentation and erythema while improving hydration and elasticity in 20 women with photoaged skin, with neither acid proving definitively more effective overall though ascorbic acid showed slightly greater skin lightening. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/34877760/))
- Combining fractional microneedle radiofrequency with a topical antioxidant serum significantly reduced wrinkle severity by 29.9% versus 18.0%, increased elasticity by 12.9% versus 2.3%, and improved aesthetic outcomes in 31 participants compared to radiofrequency and placebo. ([The Journal of Dermatological Treatment, 2025](https://pubmed.ncbi.nlm.nih.gov/40464749/))
- Topical ferulic acid-containing formulations effectively reduce skin erythema, hyperpigmentation, and signs of aging in adults compared to baseline or alternative conditions. ([The Journal of Clinical and Aesthetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40538529/))

## What reviewers say

Based on a very large amount of data, this product is highly regarded for brightening the complexion, evening skin tone, and reducing discoloration such as dark spots and melasma, particularly benefiting those with normal, oily, combination, or acne-prone skin. Many users report achieving smoother, more radiant skin and a decrease in fine lines. However, a significant number of reviews mention the high cost, a strong scent, and occasional issues with stickiness or packaging.

- Liked: Brightens skin (mostly mentioned)
- Liked: Fades discoloration (often mentioned)
- Liked: Lightweight texture (often mentioned)
- Disliked: High price point (often mentioned)
- Liked: Good for oily skin (sometimes noted)
- Disliked: Unpleasant scent (sometimes noted)
- Disliked: Packaging issues (rarely noted)

## How to apply

- Could be used as part of your PM routine. Start 3 times a week and build up to daily use if your skin tolerates it well.
- Apply your serum after cleansing and toning, but before putting on your moisturizer.
- Gently press 2 to 3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on clean, dry skin to help manage your blemishes safely.
- Do a patch test before your first use and avoid the delicate eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes SkinCeuticals Phloretin CF a great fit for oily acne-prone skin?

SkinCeuticals Phloretin CF is a great fit because its blend of ascorbic acid and ferulic acid shields oily skin from pollution while evening out your skin tone. Additionally, phloretin and ascorbic acid help control oil and support cell turnover to keep blemishes and breakouts at bay safely without causing irritation.
Sources: [Journal of the American Academy of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18603326/), [International Journal of Cosmetic Science, 2016](https://pubmed.ncbi.nlm.nih.gov/26212527/)

### Which ingredients make this serum a good fit for oily acne-prone skin?

Ascorbic acid, phloretin, and ferulic acid make this serum a great fit by shielding your oily skin from pollution, evening your skin tone, and helping control breakouts and sebum. This combination is unlikely to cause irritation while supporting clearer and brighter skin.
Sources: [Journal of the American Academy of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18603326/), [International Journal of Cosmetic Science, 2016](https://pubmed.ncbi.nlm.nih.gov/26212527/)

### What does phloretin do for oily acne-prone skin?

Phloretin helps oily acne-prone skin by slowing down the growth of acne-causing bacteria and reducing extra oil. Clinical studies show it also significantly lowers whiteheads and calms inflammation to keep your skin clear and smooth.
Sources: [International Journal of Cosmetic Science, 2016](https://pubmed.ncbi.nlm.nih.gov/26212527/), [Journal of Cosmetic Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/19146606/)

### What does vitamin C do for oily acne-prone skin?

Vitamin C helps brighten and smooth oily acne-prone skin while improving overall texture and dark spots. It is unlikely to cause breakouts and works well to keep the skin looking clear and radiant.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/), [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37128827/)

### Where does this serum go in a skincare routine for oily acne-prone skin?

This treatment goes in the evening routine after cleansing and before moisturizing, following the simple and safe approach for active serums. It is unlikely to cause irritation on oily skin, helping protect from pollution while managing breakouts.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum in your morning routine and the retinol in the evening. This helps you avoid irritation while giving your oily skin strong antioxidant protection and blemish control.
Sources: [Journal of the American Academy of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18603326/), [International Journal of Cosmetic Science, 2016](https://pubmed.ncbi.nlm.nih.gov/26212527/)

### How often should I use this serum?

This treatment is a great fit and can be used in your evening routine, starting once a week to see how your skin responds. Ascorbic acid, phloretin, and ferulic acid help protect your skin from pollution, brighten tone, and balance oil.
Sources: [Journal of the American Academy of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18603326/), [International Journal of Cosmetic Science, 2016](https://pubmed.ncbi.nlm.nih.gov/26212527/)

### Can this serum clog pores, cause breakouts or purging for oily acne-prone skin?

SkinCeuticals Phloretin CF is unlikely to cause breakouts or clog pores on oily acne-prone skin. Its ingredients help regulate oil and clear dead skin cells safely without causing irritation.
Sources: [International Journal of Cosmetic Science, 2016](https://pubmed.ncbi.nlm.nih.gov/26212527/), [Journal of Cosmetic Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/19146606/)

### Is this serum fragrance-free and alcohol-free?

It has no fragrance and contains drying alcohol (alcohol denat).

## Alternatives for oily acne-prone skin

- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/es/p/neogen-dermalogy/real-vitamin-c-serum/for/oily-acne-prone-skin) — Superior fit — €29.76 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/es/p/neogen-dermalogy/real-vita-c-serum/for/oily-acne-prone-skin) — High fit — €29.76 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/es/p/skin1004/probio-cica-intensive-ampoule/for/oily-acne-prone-skin) — High fit — €21.99 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/es/p/cerave/foaming-facial-cleanser/for/oily-acne-prone-skin) — Superior fit — €20.50 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/es/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-acne-prone-skin) — Superior fit — €36.00 at Amazon
- SPF: [Dear, Klairs All-day Airy Sunscreen](https://lovi.care/skincare/es/p/dear-klairs/all-day-airy-sunscreen/for/oily-acne-prone-skin) — Superior fit — €21.00 at Amazon

## Where to buy

- Amazon.de: €171.50 (https://www.amazon.de/dp/B001CEWDHG?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- Lookfantastic: €194.35 (https://www.lookfantastic.es/p/skinceuticals-phloretin-cf-antioxidant-serum-for-normal-combination-discolouration-prone-skin-types/11705728/)
Prices checked 17 Oct – 6 Nov 2026.

## Ingredients

Water, Dipropylene Glycol, Alcohol Denat, Ascorbic Acid, Butylene Glycol, Triethyl Citrate, Phloretin, Ferulic Acid
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/skinceuticals/phloretin-cf/for/oily-acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/skinceuticals/phloretin-cf/for/oily-acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/skinceuticals/phloretin-cf/for/oily-acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/skinceuticals/phloretin-cf/for/oily-acne-prone-skin
- France: https://lovi.care/skincare/fr/p/skinceuticals/phloretin-cf/for/oily-acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/skinceuticals/phloretin-cf/for/oily-acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/skinceuticals/phloretin-cf/for/oily-acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/skinceuticals/phloretin-cf/for/oily-acne-prone-skin (this page)
- Canada: https://lovi.care/skincare/ca/p/skinceuticals/phloretin-cf/for/oily-acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/skinceuticals/phloretin-cf/for/oily-acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/skinceuticals/phloretin-cf/for/oily-acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/skinceuticals/phloretin-cf/for/oily-acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/skinceuticals/phloretin-cf/for/oily-acne-prone-skin