SkinCeuticals Emollience for mature skin

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Questions and answers

What the research says

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• Apigenin protects against UVA-induced cytotoxicity and senescence in normal human dermal fibroblasts, decreases MMP-1 expression, and when applied topically as a cream in human subjects, increases dermal density and elasticity while reducing fine wrinkle length, skin evenness, moisture content, and transepidermal water loss compared to control cream.

  International Journal of Molecular Medicine, 2016

• Topical application of a water-in-oil emulsion containing 2% Muscat hamburg grape seed extract significantly improved melanin, elasticity, and sebum content compared to a placebo in human volunteers over 8 weeks, with no reported skin hypersensitivity.

  International Journal of Cosmetic Science, 2015

• Oligomeric proanthocyanidin topical cream and lotion significantly reduced UV-induced erythema by 45.9% and 53.1% respectively and increased skin hydration by nearly 20% in human subjects, with dietary supplementation providing additional suppression of erythema and higher skin hydration.

  Skin Pharmacology and Physiology, 2007

• The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.

  Journal of Cosmetic Dermatology, 2020

• Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.

  International Journal of Cosmetic Science, 2001

• Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.

  Journal of Drugs in Dermatology, 2012

• Topical application of sesame oil combined with standard care significantly reduced infusion-related phlebitis in adults compared to a control condition, with a risk ratio of 0.54.

  Complementary Therapies in Medicine, 2025

• Sesamol loaded silver nanoparticles gel showed a twofold increase in skin permeation and higher antioxidant activity compared to conventional formulations, demonstrating potential for topical wound healing delivery.

  Current Pharmaceutical Design, 2024

• Treatment with moderately ozonated sesame oil accelerates cutaneous wound closure and enhances cell response, angiogenesis, and VEGF and cyclin D1 expression in SKH1 mice compared to oil with lower or higher peroxide values and controls.

  Wound Repair and Regeneration, 2011

• Grapeseed oil-loaded dermocosmetic nanoemulgel applied on the cheeks of healthy volunteers significantly reduced skin melanin, erythema, sebum production, and pores while increasing moisture and elasticity compared to a placebo.

  Journal of Cosmetic Dermatology, 2022

• Topical treatment with cranberry oil and grape oil improved wound healing in rats, with cranberry oil showing an 88.1% wound area reduction and grape oil showing 84.6% compared to 74.1% in controls and 78.4% in the mupirocin standard group on day 13.

  Phytotherapy Research, 2011

• An ionic liquid-based grapeseed oil emulsion increased transdermal penetration by 4.63-fold and improved skin hydration, firmness, elasticity, and facial wrinkles after 28 days of continuous use compared to ordinary emulsion.

  Pharmaceuticals, 2024

• A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo.

  Clinical Pharmacology, 2018

• Topical aloe vera gel significantly accelerated split-thickness skin graft donor-site healing compared to placebo in 12 patients, but showed no significant difference in pain relief.

  Plastic and Reconstructive Surgery, 2018

• Topical application of Aloe vera cream reduced postoperative pain at rest and during defecation, accelerated wound healing at two weeks, and decreased analgesic requirements in patients after open hemorrhoidectomy compared to placebo.

  Journal of Alternative and Complementary Medicine, 2010

Ingredients

Water, Glycerin, Sesamum Indicum Oil, Propylene Glycol, Glyceryl Stearate, Vitis Vinifera Seed Oil, Rosa Canina Oil Fruit, Macadamia Ternifolia Seed Oil, Mangifera Indica Seed Butter, Stearic Acid, Palmitic Acid, Triethanolamine, Caprylic Capric Glycerides, Phenoxyethanol, Panthenol, Carbomer, Chlorphenesin, Caprylyl Glycol, Aloe Barbadensis, Disodium Edta, Allantoin, Laminaria Ochroleuca Extract, Ginkgo Biloba Extract, Chlorella Vulgaris Extract, Algae Extract, Prunus Cerasus Fruit Extract, Fagus Sylvatica Extract, Lavandula Angustifolia Oil, Rosmarinus Officinalis Oil Leaf, Prunus Armeniaca Kernel Oil, Peppermint Oil, Linalool, Peppermint Extract, Chamomilla Recutita Extract

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.