# SKIN1004 Madagascar Centella Hyalu-Cica First Ampoule for dry skin

**Lovi Fit: Superior fit for dry skin.**
Dry Skin Fit: Superior · Effectiveness: Superior · Safety: Excellent.

Page: https://lovi.care/skincare/es/p/skin1004/madagascar-centella-hyalu-cica-first-ampoule/for/dry-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Brand: [SKIN1004](https://lovi.care/skincare/es/brands/skin1004)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/es/best/moisturizers)

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best moisturizers for dry skin.

## Why this fit

- Excellent suitability for your dry skin is provided by high concentrations of Sodium Hyaluronate and Hydrolyzed Hyaluronic Acid, which offer superior hydration, complemented by Centella Asiatica Extract and Anastatica Hierochuntica Extract for effective barrier repair.
- Glycerin and Butylene Glycol further enhance humectant action, ensuring your skin remains smooth and hydrated throughout the day.
- The product is safe for your skin, with no risks of irritation due to the absence of harsh ingredients and the inclusion of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/es/p/skin1004/madagascar-centella-hyalu-cica-first-ampoule/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/es/p/skin1004/madagascar-centella-hyalu-cica-first-ampoule/for/dry-skin): Superior (this page)
- [Combination skin](https://lovi.care/skincare/es/p/skin1004/madagascar-centella-hyalu-cica-first-ampoule/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/es/p/skin1004/madagascar-centella-hyalu-cica-first-ampoule/for/sensitive-skin): Superior
- [Acne-prone skin](https://lovi.care/skincare/es/p/skin1004/madagascar-centella-hyalu-cica-first-ampoule/for/acne-prone-skin): Superior
- [Skin with dark spots](https://lovi.care/skincare/es/p/skin1004/madagascar-centella-hyalu-cica-first-ampoule/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/es/p/skin1004/madagascar-centella-hyalu-cica-first-ampoule/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/es/p/skin1004/madagascar-centella-hyalu-cica-first-ampoule/for/dry-sensitive-skin): Superior
- [Oily acne-prone skin](https://lovi.care/skincare/es/p/skin1004/madagascar-centella-hyalu-cica-first-ampoule/for/oily-acne-prone-skin): High

## Key ingredients

Centella Asiatica, Sodium Hyaluronate, Niacinamide, Glycerin, Curcuma Longa Extract

## What the research says

- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Profhilo gel combined with Dysport Botox significantly improved skin hydration, skin thickness, and GAIS scores compared to Dysport Botox injection alone in 19 participants seeking neck rejuvenation. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/35775872/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Profhilo treatment led to significant improvements in superficial skin hydration and transepidermal water loss over time in Chinese females, while demonstrating good product tolerability. ([Aesthetic Plastic Surgery, 2026](https://pubmed.ncbi.nlm.nih.gov/40921777/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Topical application of curcumin or turmeric treats various skin conditions by leveraging antioxidant, anti-inflammatory, and antimicrobial properties. ([Skin Pharmacology and Physiology, 2023](https://pubmed.ncbi.nlm.nih.gov/38008088/))
- Topical formulations of curcumin target oxidative damage and inflammation to improve wound healing in animal models. ([Drug Discovery Today, 2017](https://pubmed.ncbi.nlm.nih.gov/28711364/))
- A curcumin-loaded spanlastic anti-aging gel utilizing formula F5 incorporated into 2% HPMC E50 demonstrated sustained release action, compatibility, and the ability to penetrate skin layers to a depth of about 112.5 um without signs of irritation. ([Saudi Pharmaceutical Journal, 2024](https://pubmed.ncbi.nlm.nih.gov/38178851/))

## What reviewers say

Based on a very large amount of data, this ampoule is widely praised as a holy grail for oily, combination, and sensitive skin types due to its incredibly lightweight, water-like texture that deeply hydrates without clogging pores. While it excels at soothing redness and prepping the skin for makeup, users with very dry skin often find it insufficient as a standalone moisturizer, particularly during colder months.

- Liked: Lightweight hydration (mostly mentioned)
- Liked: Rapid absorption (mostly mentioned)
- Liked: Soothing and calming (often mentioned)
- Liked: Makeup compatibility (sometimes noted)
- Liked: Value for money (sometimes noted)
- Disliked: Insufficient for dry (sometimes noted)
- Disliked: Breakouts rare (rarely noted)
- Disliked: Lack of wow (rarely noted)
- Disliked: Runny texture (rarely noted)

## How to apply

- Could be used as part of your AM or PM routine. Start using it 3 times a week and work your way up to daily use.
- Apply your moisturizer after your toner and before your sunscreen in the morning. At night, use it as the final step after your serum.
- Gently press a small amount of the moisturizer into your skin. Avoid rubbing to keep your dry skin happy.
- Apply the moisturizer on slightly damp skin to help lock in extra hydration. This is great for soothing dry and flaky areas .
- Avoid the sensitive eye area and do a patch test before your first use .
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes SKIN1004 Hyalu-Cica First Ampoule one of the best fits for dry skin?

This moisturizing treatment is one of the best fits for your dry skin because it uses high levels of hyaluronic acid to draw in moisture, alongside centella asiatica and resurrection plant extracts to repair your skin barrier. Glycerin and butylene glycol add extra hydrating power to keep your skin smooth all day long, and the gentle formula is unlikely to cause irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Which ingredients make this ampoule a good fit for dry skin?

This ampoule is a very good fit for dry skin thanks to high concentrations of sodium hyaluronate and hydrolyzed hyaluronic acid that bring deep hydration, alongside centella asiatica extract and anastatica hierochuntica extract which help repair the skin barrier. Glycerin and butylene glycol also add extra moisture to keep your skin smooth all day long.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Centella Asiatica do for dry skin?

Centella asiatica helps dry skin by boosting moisture levels and keeping water locked in to make the skin feel softer and smoother. It also calms redness and supports the natural barrier to prevent everyday irritation.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Hyaluronic Acid do for dry skin?

Hyaluronic acid draws moisture into dry skin, giving an immediate and lasting boost in hydration that helps smooth out fine lines and soften rough patches. It is very gentle and unlikely to cause irritation while improving overall skin smoothness and plumpness.
Sources: [Dermatology and Therapy, 2021](https://pubmed.ncbi.nlm.nih.gov/34176098/), [Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/)

### Where does this ampoule go in a skincare routine for dry skin?

This ampoule goes in the evening routine after cleansing and before moisturizing. Putting treatments in the evening keeps things simple and protects your skin around sun exposure.

### Can I use this ampoule with retinol, and in what order?

You can use this ampoule with retinol, applying the ampoule before your retinol product to help keep your skin calm and hydrated. Using a hydrating and barrier-repairing treatment alongside retinol is unlikely to cause irritation and may help your dry skin adjust more comfortably.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### How often should I use this ampoule?

This ampoule is used in the evening as part of your routine for dry skin. Daily application helps keep dry skin smooth and deeply hydrated.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this ampoule clog pores, cause breakouts or purging for dry skin?

This ampoule is unlikely to cause breakouts or clog pores on dry skin, as it has a very low risk of irritation and includes soothing ingredients. It helps keep your skin calm and smooth without heavy oils.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Can I use this ampoule around the eyes or on my body?

You can use this moisturizing treatment around the eyes and on the body because it is very safe and gentle. Its hydrating ingredients help smooth dry skin on thinner areas like the eyelids and body without causing irritation.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [Polymers, 2023](https://pubmed.ncbi.nlm.nih.gov/37896378/)

### Is this ampoule fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for dry skin

- [Kiehl's Midnight Recovery Concentrate](https://lovi.care/skincare/es/p/kiehl-s/midnight-recovery-concentrate/for/dry-skin) — Average fit — €54.78 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/es/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — €8.85 at Amazon
- Hydrating Toner: [Paula's Choice Resist Advanced Replenishing Toner](https://lovi.care/skincare/es/p/paula-s-choice/advanced-replenishing-toner/for/dry-skin) — Superior fit — €34.00 at Amazon
- SPF: [Purito Daily Soft Touch Sunscreen](https://lovi.care/skincare/es/p/purito/daily-soft-touch-sunscreen/for/dry-skin) — Superior fit — €12.98 at Amazon

## Where to buy

- Amazon.de: €22.99 (https://www.amazon.de/dp/B0B5WRBK93?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- Notino: €16.50 (https://www.notino.es/skin1004/madagascar-centella-hyalu-cica-first-ampoule-serum-hidratante-revitalizante/p-16231301/)
Prices checked 16 Oct – 6 Nov 2026.

## Ingredients

Centella Asiatica Extract, Butylene Glycol, Niacinamide, 1,2-Hexanediol, Water, Hydroxyacetophenone, Carbomer, Glycereth-25 Pca Isostearate, Ethylhexylglycerin, Tromethamine, Sodium Hyaluronate, Betula Platyphylla Japonica Juice, Melia Azadirachta Leaf Extract, Melia Azadirachta Flower Extract, Propanediol, Musa Sapientum Flower Extract, Coccinia Indica Fruit Extract, Rosa Damascena Flower Water, Pyrus Communis Fruit Extract, Prunus Domestica Fruit Extract, Aloe Barbadensis Flower Extract, Cucumis Melo Fruit Extract, Solanum Melongena Fruit Extract, Hedera Helix Stem Extract Leaf, Ocimum Sanctum Leaf Extract, Glycerin, Anastatica Hierochuntica Extract, Corallina Officinalis Extract, Curcuma Longa Root Extract, Hydrolyzed Hyaluronic Acid, Portulaca Oleracea Extract, Artemisia Princeps Extract, Rhodiola Rosea Root Extract
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/skin1004/madagascar-centella-hyalu-cica-first-ampoule/for/dry-skin
- United Kingdom: https://lovi.care/skincare/uk/p/skin1004/madagascar-centella-hyalu-cica-first-ampoule/for/dry-skin
- Ireland: https://lovi.care/skincare/ie/p/skin1004/madagascar-centella-hyalu-cica-first-ampoule/for/dry-skin
- Germany: https://lovi.care/skincare/de/p/skin1004/madagascar-centella-hyalu-cica-first-ampoule/for/dry-skin
- France: https://lovi.care/skincare/fr/p/skin1004/madagascar-centella-hyalu-cica-first-ampoule/for/dry-skin
- Italy: https://lovi.care/skincare/it/p/skin1004/madagascar-centella-hyalu-cica-first-ampoule/for/dry-skin
- Netherlands: https://lovi.care/skincare/nl/p/skin1004/madagascar-centella-hyalu-cica-first-ampoule/for/dry-skin
- Spain: https://lovi.care/skincare/es/p/skin1004/madagascar-centella-hyalu-cica-first-ampoule/for/dry-skin (this page)
- Canada: https://lovi.care/skincare/ca/p/skin1004/madagascar-centella-hyalu-cica-first-ampoule/for/dry-skin
- Australia: https://lovi.care/skincare/au/p/skin1004/madagascar-centella-hyalu-cica-first-ampoule/for/dry-skin
- Singapore: https://lovi.care/skincare/sg/p/skin1004/madagascar-centella-hyalu-cica-first-ampoule/for/dry-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/skin1004/madagascar-centella-hyalu-cica-first-ampoule/for/dry-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/skin1004/madagascar-centella-hyalu-cica-first-ampoule/for/dry-skin