# Rodan + Fields Intensive Renewing Serum for acne-prone skin

**Lovi Fit: Average fit for acne-prone skin.**
Combination Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/es/p/rodan-fields/intensive-renewing-serum/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Brand: [Rodan + Fields](https://lovi.care/skincare/es/brands/rodan-fields)
Category: [Serums and treatments](https://lovi.care/skincare/es/best/serums)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for acne-prone skin; other serums fit it better.

## Why this fit

- Offers moderate suitability for your combination skin as retinal and palmitoyl hexapeptide-14 provide some benefits for skin renewal and collagen stimulation, but may lack sufficient ingredients for optimal results in all areas.
- The product offers general skincare benefits like hydration and cleansing, which you would notice, but the benefits are mostly supportive for your acne, blemishes, and breakouts due to the presence of retinal and retinyl palmitate in concentrations that offer moderate exfoliation.
- The safety profile is good, with no risks of irritation for your combination skin due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/es/p/rodan-fields/intensive-renewing-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/es/p/rodan-fields/intensive-renewing-serum/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/es/p/rodan-fields/intensive-renewing-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/es/p/rodan-fields/intensive-renewing-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/es/p/rodan-fields/intensive-renewing-serum/for/acne-prone-skin): Average (this page)
- [Skin with dark spots](https://lovi.care/skincare/es/p/rodan-fields/intensive-renewing-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/es/p/rodan-fields/intensive-renewing-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/es/p/rodan-fields/intensive-renewing-serum/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/es/p/rodan-fields/intensive-renewing-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Retinal, Retinyl Palmitate, Palmitoyl Hexapeptide-14, Bis-Ethylhexyl Hydroxydimethoxy Benzylmalonate, Hydroxyapatite

## What the research says

- Twice daily application of retinaldehyde 0.1% and 0.05% creams for 3 months improved skin texture and hydration and reduced transepidermal water loss in 40 female Korean volunteers, with only the 0.1% cream significantly improving the melanin index. ([Journal of Cosmetic Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29663701/))
- Topical retinaldehyde demonstrated significant antibacterial activity against gram-positive bacteria both in vitro and in vivo, leading to decreased bacterial counts without inducing resistance. ([Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12218231/))
- Topical 0.05% retinaldehyde applied over 1 year significantly increased epidermal thickness of the temple and cutaneous elasticity compared to an emollient control group in 40 aging skin patients. ([Dermatology, 1999](https://pubmed.ncbi.nlm.nih.gov/10473959/))
- Over-the-counter retinol products provided only weak evidence for a mild ameliorating effect on fine facial skin wrinkle lines in randomized, double-blind, vehicle-controlled trials, and major methodological flaws call the validity of positive results into question. ([The Journal of Clinical and Aesthetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/34980969/))
- A cosmetic niacinamide/peptide/retinyl propionate regimen significantly improved periorbital wrinkle appearance relative to a 0.02% tretinoin regimen at 8 weeks with comparable benefits at 24 weeks, while demonstrating significantly better tolerability in 196 women. ([The British Journal of Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/20374604/))
- A novel triple-active cosmetic formulation containing 4-hexylresorcinol, retinyl propionate, and niacinamide improved the visual appearance of photoageing similarly to 0.02% tretinoin and reversed a consensus gene signature associated with ageing in female adults while causing less skin irritation. ([International Journal of Cosmetic Science, 2024](https://pubmed.ncbi.nlm.nih.gov/38685700/))
- Treatment with 2% bis-ethylhexyl hydroxydimethoxy benzylmalonate (HDBM) resulted in a significant reduction of sebum excretion and efficacy against inflamed/red lesions compared to placebo in 44 test subjects with blemished skin over 8 weeks. ([Clinical, Cosmetic and Investigational Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22956882/))
- The combination of botulinum toxin and calcium hydroxylapatite applied together produced higher and earlier satisfaction rates and improved hydration in the lower face and neck region compared to calcium hydroxylapatite alone in 15 participants. ([Clinical, Cosmetic and Investigational Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37823019/))
- Topically applied calcium hydroxylapatite successfully penetrated fractional laser-induced skin defects and remained in the healing skin for at least six weeks, inducing collagen production around the microspheres in a human volunteer. ([Lasers in Surgery and Medicine, 2025](https://pubmed.ncbi.nlm.nih.gov/39160686/))
- Calcium ions from nanophased hydroxyapatite embedded in collagen nanofibers significantly enhanced human dermal fibroblasts, keratinocytes, and hMSCs growth and proliferation, prevented pathogenic bacteria adhesion, enabled hMSCs differentiation, and caused no adverse reaction in rat subcutaneous implantation. ([Nanomedicine, 2021](https://pubmed.ncbi.nlm.nih.gov/33421622/))

## Why other serums fit acne-prone skin better

- Topical nicotinamide plus an antibacterial adhesive agent and zinc-pyrrolidone carboxylic acid combined with adapalene significantly reduced noninflammatory acne lesions by the second week of therapy compared to placebo with adapalene in patients with moderate acne vulgaris. ([The Journal of Clinical and Aesthetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32983333/))
- A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo. ([Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/))
- Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo. ([BioMed Research International, 2022](https://pubmed.ncbi.nlm.nih.gov/35342760/))

## What reviewers say

Based on a very large amount of data, users frequently report that this serum effectively smooths skin texture, reduces the appearance of fine lines and wrinkles, and promotes a firmer, more youthful complexion. While many appreciate the results for various skin types, some users feel the product is overpriced and note that similar results can be achieved with more affordable alternatives. This should be definitely taken into account.

- Liked: Reduces fine lines (often mentioned)
- Liked: Smoother skin texture (often mentioned)
- Disliked: High price point (often mentioned)
- Liked: Convenient capsule delivery (sometimes noted)
- Liked: Effective, gentle formula (sometimes noted)
- Disliked: Customer service issues (sometimes noted)
- Disliked: Lack of results (rarely noted)

## How to apply

- Use your serum as part of your PM routine and start 3x/week before working up to daily use.
- Apply this treatment after cleansing and toner, and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the product on clean, dry skin to help manage your breakouts safely.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Intensive Renewing Serum work for acne-prone skin?

This treatment works moderately well for acne-prone skin because retinal and retinyl palmitate offer some supportive exfoliation for breakouts, though other products fit this skin better. An acne-prone skin type needs effective ingredients like niacinamide, propolis, or zinc pca for excellent blemish benefits and oil control without causing excess oiliness or dryness.
Sources: [International Journal of Nanomedicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34211271/)

### Which ingredients make this serum a good fit for acne-prone skin?

Retinal and retinyl palmitate make this serum a fit for acne-prone skin by offering moderate exfoliation to help with breakouts. Treatments that fit this skin better also need ingredients like niacinamide, zinc PCA, and propolis to control oiliness and soothe blemishes.
Sources: [International Journal of Nanomedicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34211271/)

### What does Retinal do for acne-prone skin?

Retinal helps clear acne-prone skin by reducing blemishes, clogged pores, and redness while improving overall skin texture. Side effects are very uncommon when using this ingredient.
Sources: [International Journal of Cosmetic Science, 2026](https://pubmed.ncbi.nlm.nih.gov/42572367/), [Clinical and Experimental Dermatology, 1999](https://pubmed.ncbi.nlm.nih.gov/10564319/)

### What does Retinyl Palmitate do for acne-prone skin?

Retinyl palmitate helps clear up acne-prone skin by reducing acne bumps and blemish counts. It is unlikely to cause heavy irritation, making it much gentler on the skin than stronger treatments.
Sources: [International Journal of Nanomedicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34211271/)

### Where does it go in a skincare routine for acne-prone skin?

This treatment goes in the evening routine after cleansing and before moisturizing. It has a good safety profile with no harsh ingredients, but acne-prone skin needs a product with stronger targeted blemish-fighting ingredients for optimal results.

### Can I use this serum with glycolic acid, and in what order?

You can use this serum in your evening routine, but using it with glycolic acid may cause too much peeling and redness on acne-prone skin. It is best to alternate them on different nights or apply glycolic acid in the morning and this treatment at night. To work best for your skin, this type of product needs a balanced mix of soothing ingredients and gentle exfoliants that target breakouts without overwhelming your face.
Sources: [American Family Physician, 2012](https://pubmed.ncbi.nlm.nih.gov/23062156/)

### How often should I use it?

You can use this treatment in your evening routine, starting just once a week to see how your skin reacts. Because it contains gentle exfoliants, people who tolerate it well can carefully use it more often. To work best for acne-prone skin, this type of product needs extra clarifying and soothing ingredients.
Sources: [International Journal of Nanomedicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34211271/), [Facial Plastic Surgery, 2014](https://pubmed.ncbi.nlm.nih.gov/24488631/)

### Can this serum clog pores, cause breakouts or purging for acne-prone skin?

This serum is unlikely to cause irritation on acne-prone skin, as it contains no harsh ingredients and offers gentle exfoliation from retinal and retinyl palmitate. However, because it provides only moderate support for breakouts, acne-prone skin often needs products packed with stronger clarifying ingredients and deep pore-clearing agents for best results.
Sources: [International Journal of Nanomedicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34211271/)

### Is it fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for acne-prone skin

- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/es/p/skinceuticals/c-e-ferulic/for/acne-prone-skin) — Superior fit — €169.99 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/es/p/neogen-dermalogy/real-vitamin-c-serum/for/acne-prone-skin) — Superior fit — €29.76 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/es/p/skin1004/probio-cica-intensive-ampoule/for/acne-prone-skin) — High fit — €21.99 at Amazon

## Pairs well with

- Cleanser: [B.LAB Matcha Hydrating Foam Cleanser](https://lovi.care/skincare/es/p/b-lab/matcha-hydrating-foam-cleanser/for/acne-prone-skin) — Superior fit — €11.99 at Amazon
- Hydrating Toner: [Paula's Choice Resist Advanced Replenishing Toner](https://lovi.care/skincare/es/p/paula-s-choice/advanced-replenishing-toner/for/acne-prone-skin) — Superior fit — €34.00 at Amazon
- Moisturizer: [SKIN1004 Centella Cream](https://lovi.care/skincare/es/p/skin1004/centella-cream/for/acne-prone-skin) — Superior fit — €17.49 at Amazon

## Where to buy

No store in Spain has a checked price for this product, so the page shows none.

## Ingredients

Bis-Ethylhexyl Hydroxydimethoxy Benzylmalonate, C12-15 Alkyl Benzoate, Cyclopentasiloxane, Dimethicone, Ethoxydiglycol, Ethylhexyl Hydroxystearate, Hydroxyapatite, Palmitoyl Hexapeptide-14, Polysilicone-11, Retinal, Retinyl Palmitate
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/rodan-fields/intensive-renewing-serum/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/rodan-fields/intensive-renewing-serum/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/rodan-fields/intensive-renewing-serum/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/rodan-fields/intensive-renewing-serum/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/rodan-fields/intensive-renewing-serum/for/acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/rodan-fields/intensive-renewing-serum/for/acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/rodan-fields/intensive-renewing-serum/for/acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/rodan-fields/intensive-renewing-serum/for/acne-prone-skin (this page)
- Canada: https://lovi.care/skincare/ca/p/rodan-fields/intensive-renewing-serum/for/acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/rodan-fields/intensive-renewing-serum/for/acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/rodan-fields/intensive-renewing-serum/for/acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/rodan-fields/intensive-renewing-serum/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/rodan-fields/intensive-renewing-serum/for/acne-prone-skin