Rael Beauty Calming Cica Cleansing Water for combination skin

How to apply

Questions and answers

What the research says

• Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment.

  American Journal of Clinical Dermatology, 2002

• Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements.

  Indian Journal of Pharmaceutical Sciences, 2016

• A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability.

  The Journal of Dermatological Treatment, 2017

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment.

  Journal of Cosmetic Dermatology, 2025

• Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing.

  Journal of Alternative and Complementary Medicine, 2020

• Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects.

  Journal of Cosmetic Dermatology, 2019

• Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline.

  Experimental Dermatology, 2008

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.

  Journal of Cosmetic Dermatology, 2020

• Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.

  International Journal of Cosmetic Science, 2001

• Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.

  Journal of Drugs in Dermatology, 2012

• Anti-aging cream with 3HFWC+ demonstrated a statistically significant increase of paramagnetic properties of the skin and showed beneficial effects on water content in the stratum corneum compared to vehiculum alone.

  Journal of Cosmetic Dermatology, 2021

• Application of fullerene nanoemulsion twice daily for 28 days significantly increased the mean collagen score by 33.29% and skin hydration by 43.12% without increasing transepidermal water loss in human skin.

  European Journal of Pharmaceutical Sciences, 2015

• Topical application of fullerene gel twice a day in patients with acne vulgaris significantly reduced inflammatory lesions and pustules, inhibited sebum production, and increased skin water content over 8 weeks.

  Nanomedicine, 2011

• Bee venom, Ficus carica, and Geranium essential oil exhibit common anti-inflammatory, antibacterial, and antioxidant pharmacological actions, offering potential therapeutic and safe topical applications for combating various skin conditions and for skin care.

  Life, 2024

• Oral RGEO at 100 mg/kg reduced carrageenan-induced paw edema similarly to diclofenac, while topical RGEO reduced croton oil-induced ear edema by 73% at 5 µl and 88% at 10 µl in rodents.

  The Libyan Journal of Medicine, 2013

• Cutaneous application of geranium essential oil dose-dependently suppressed neutrophil accumulation and inflammatory symptoms in skin lesions of mice compared to untreated curdlan-induced inflammation.

  Journal of Inflammation, 2005

Ingredients

Water, Glycerin, Butylene Glycol, 1,2-Hexanediol, Sodium Coco Pg-Dimonium Chloride Phosphate, Centella Asiatica Leaf Extract, Sodium Hyaluronate, Fullerenes, Sodium Chloride, Panthenol, Xylitol, Allantoin, Polyglyceryl-10 Laurate, Dipropylene Glycol, Polyglyceryl-4 Laurate, Pelargonium Graveolens Oil Flower Geranium Oil Flower, Eclipta Prostrata Extract, Melia Azadirachta Leaf Extract, Melia Azadirachta Flower Extract, Curcuma Longa Root Extract, Corallina Officinalis Extract, Adenosine, Arginine, Brassica Oleracea Italica Extract, Camellia Sinensis Leaf Extract, Caprylyl Glycol, Carbomer, Eriobotrya Japonica Leaf Extract, Ethylhexylglycerin, Lentinus Edodes Extract, Psidium Guajava Leaf Extract, Sasa Quelpaertensis Extract, Pvp, Styrene Acrylates Copolymer, Citric Acid

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.