# Prequel UREA ADVANCED RELIEF MOISTURIZING MILK for oily acne-prone skin

**Lovi Fit: Average fit for oily acne-prone skin.**
Oily Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/es/p/prequel/urea-advanced-relief-moisturizing-milk/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Brand: [Prequel](https://lovi.care/skincare/es/brands/prequel)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/es/best/moisturizers)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for oily acne-prone skin; other moisturizers fit it better.

## Why this fit

- Offers moderate suitability for your oily skin as urea and niacinamide provide hydration and some oil control, though it lacks sufficient mattifying ingredients for optimal results.
- The product provides excellent moisturizing benefits due to urea and glycerin, which hydrate and enhance barrier resilience, but these benefits are largely supportive rather than directly addressing your acne, blemishes, and breakouts.
- The safety profile is excellent, with no risks of irritation for your oily skin due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/es/p/prequel/urea-advanced-relief-moisturizing-milk/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/es/p/prequel/urea-advanced-relief-moisturizing-milk/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/es/p/prequel/urea-advanced-relief-moisturizing-milk/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/es/p/prequel/urea-advanced-relief-moisturizing-milk/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/es/p/prequel/urea-advanced-relief-moisturizing-milk/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/es/p/prequel/urea-advanced-relief-moisturizing-milk/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/es/p/prequel/urea-advanced-relief-moisturizing-milk/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/es/p/prequel/urea-advanced-relief-moisturizing-milk/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/es/p/prequel/urea-advanced-relief-moisturizing-milk/for/oily-acne-prone-skin): Average (this page)

## Key ingredients

Urea, Niacinamide, Shea Butter, Glycerin, Dimethicone

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical 40% urea cream achieved improvement in less time and showed superiority over 12% ammonium lactate lotion in skin roughness, fissure reduction, thickness, and dryness at day 14 in patients treated for moderate to severe xerosis. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/11978141/))
- Topical treatment with K101 achieved a significantly higher mycological cure rate compared to placebo in patients with ≤50% nail involvement (27.2% vs 10.4%), while showing early visible improvements in nail appearance and no safety issues. ([Mycoses, 2012](https://pubmed.ncbi.nlm.nih.gov/22681227/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- A combination cream of stimu-tex AS and saccharide isomerate reduced erythema, increased skin capacitance, and reduced transepidermal water loss compared to placebo in 20 subjects after fractional CO2 laser procedure without causing serious adverse events. ([Lasers in Medical Science, 2025](https://pubmed.ncbi.nlm.nih.gov/41134387/))
- A skin barrier restoring cream with shea butter, silkflo, and vitamin E increased type I procollagen synthesis, enhanced antioxidant enzyme activity, decreased reactive oxygen species generation, and promoted hyaluronic acid production in H2O2-stimulated human keratinocyte cells compared to untreated cells. ([International Journal of Cosmetic Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39528438/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Wearing an N95 mask alone compared to using dimethicone cream or hydrocolloid dressing caused more adverse skin reactions among 73 military health care workers, with no significant differences in fit test failure rates between groups. ([Military Medicine, 2024](https://pubmed.ncbi.nlm.nih.gov/38771104/))
- A dimethicone skin protectant lotion significantly decreased visual scoring and transepidermal water loss compared to vehicle control and SLS-only treated sites in 12 healthy humans exposed to sodium lauryl sulfate. ([Skin Research and Technology, 2000](https://pubmed.ncbi.nlm.nih.gov/11428946/))
- Treatment with a moisturizer containing dimethicone and glycerine increased epidermal thickness by 0.019 mm, improved barrier function by decreasing transepidermal water loss by 13%, decreased melanin intensity, and induced keratins 6 and 16 in fifteen women with moderately photoaged forearms. ([Clinical and Experimental Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17137484/))

## Why other moisturizers fit oily acne-prone skin better

- A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38366684/))
- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- A facial serum containing snail secretion filtrate, Calendula officinalis, and Glycyrrhiza glabra root extract significantly reduced inflammatory acne lesions compared to placebo in 66 participants with mild-to-moderate maskne over 12 weeks. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35763437/))

## What reviewers say

This 10% urea moisturizer is highly effective at smoothing rough skin texture and providing deep hydration, especially beneficial for conditions like Keratosis Pilaris. Users frequently praise its lightweight, glowy finish and excellent value for money. However, a notable number of reviews mention issues with the product pilling and occasional problems with the pump packaging arriving broken.

- Liked: Deep hydration (mostly mentioned)
- Liked: Effective smoothing (often mentioned)
- Liked: Elegant finish (often mentioned)
- Liked: Great value (often mentioned)
- Disliked: Packaging malfunctions (sometimes noted)
- Disliked: Pilling issues (sometimes noted)
- Disliked: Facial irritation (rarely noted)
- Disliked: Sensory discomfort (rarely noted)

## How to apply

- Use this AM and PM routine every day to help clear your skin. Always remember to finish with SPF in the morning.
- Apply the moisturizer after your cleanser and toner, right before your SPF during the day.
- Gently press a small amount into your skin and avoid rubbing to keep pores clear.
- Apply on clean, slightly damp skin to help the product absorb better and control oil.
- Avoid the sensitive eye area and do a simple patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Prequel Urea Advanced Relief Moisturizing Milk work for oily acne-prone skin?

This product works moderately well for oily acne-prone skin, providing helpful hydration and some oil control from urea and niacinamide, but it lacks sufficient mattifying ingredients for optimal results. A product of this type needs lightweight hydrating ingredients, oil-absorbing or mattifying agents, and pore-clearing actives to truly balance and manage oily, breakout-prone skin.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this milk a good fit for oily acne-prone skin?

Urea and niacinamide make this moisturizing treatment a moderate fit for your oily skin because they provide hydration and some oil control, though this type of product also needs mattifying ingredients and lightweight, pore-clearing agents to work best for acne-prone skin.

### What does Urea do for oily acne-prone skin?

Urea is generally not the best choice for oily, acne-prone skin because it is designed to deeply hydrate and soften dry skin, which can feel too heavy. Oily skin needs lightweight hydration and ingredients that help keep pores clear rather than rich moisturizers.

### What does Niacinamide do for oily acne-prone skin?

Niacinamide helps balance oil production, calms redness, and is unlikely to irritate oily, acne-prone skin while improving blemishes. Clinical tests show it reduces excess oil and helps clear up both inflammatory and non-inflammatory acne breakouts.
Sources: [Journal of Cosmetic and Laser Therapy, 2006](https://pubmed.ncbi.nlm.nih.gov/16766489/), [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38299457/)

### Where does this milk go in a skincare routine for oily acne-prone skin?

This moisturizing treatment goes towards the end of your morning and evening routines as your daily moisturizer. It helps hydrate your skin and strengthen its barrier safely, though oily acne-prone skin needs lightweight mattifying ingredients and blemish-targeting actives for best results.
Sources: [International Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/31461548/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this milk with retinol, and in what order?

You can use this milk with retinol by applying it right after your retinol treatment to help soothe your skin and keep it soft. Using a moisturizer alongside retinol helps reduce dryness and irritation while supporting your skin barrier.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [The Journal of Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/24930436/)

### How often should I use this milk?

This moisturizing treatment works well for your oily acne-prone skin when used daily as part of your routine. It provides good hydration and helps keep your skin soft, but an oily skin type of this kind needs targeted mattifying ingredients and blemish-fighting actives to control breakouts.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this milk clog pores, cause breakouts or purging for oily acne-prone skin?

This moisturizing treatment is unlikely to cause irritation or breakouts on your oily skin due to its gentle formula, but it lacks sufficient oil-controlling ingredients to prevent shine. Oily acne-prone skin needs lightweight, mattifying ingredients that reduce excess oil alongside gentle hydration.

### Can I use this milk around the eyes or on my body?

You can use this moisturizing treatment on your body, but the thin skin around your eyes requires a dedicated eye cream for best care. The skin on your body will stay soft and comfortable thanks to its deeply hydrating ingredients, though very dry body areas may need a product with extra richness.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/)

### Is this milk fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetearyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for oily acne-prone skin

- [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/es/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/oily-acne-prone-skin) — Superior fit — €13.67 at Amazon
- [belif The True Cream Aqua Bomb](https://lovi.care/skincare/es/p/belif/the-true-cream-aqua-bomb/for/oily-acne-prone-skin) — High fit — €35.00 at Amazon
- [Purito Centella Unscented Recovery Cream](https://lovi.care/skincare/es/p/purito/centella-unscented-recovery-cream/for/oily-acne-prone-skin) — High fit — €14.94 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/es/p/cerave/foaming-facial-cleanser/for/oily-acne-prone-skin) — Superior fit — €20.50 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/es/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-acne-prone-skin) — Superior fit — €36.00 at Amazon
- SPF: [Dear, Klairs All-day Airy Sunscreen](https://lovi.care/skincare/es/p/dear-klairs/all-day-airy-sunscreen/for/oily-acne-prone-skin) — Superior fit — €21.00 at Amazon

## Where to buy

No store in Spain has a checked price for this product, so the page shows none.

## Ingredients

Water, Urea, Ethylhexyl Stearate, Caprylic Capric Triglyceride, Glycerin, Butyrospermum Parkii Butter, Cyclopentasiloxane, C12-15 Alkyl Benzoate, Polyglyceryl-6 Distearate, Sodium Citrate, Sodium Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Cetearyl Alcohol, Dimethicone, Jojoba Esters, Niacinamide, Candelilla Jojoba Rice Bran Polyglyceryl-3 Esters, C15-19 Alkane, Phenoxyethanol, Potassium Cetyl Phosphate, Citric Acid, Lauryl Glucoside, Ethylhexylglycerin, Tetrasodium Glutamate Diacetate, Tocopherol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/prequel/urea-advanced-relief-moisturizing-milk/for/oily-acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/prequel/urea-advanced-relief-moisturizing-milk/for/oily-acne-prone-skin
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- Spain: https://lovi.care/skincare/es/p/prequel/urea-advanced-relief-moisturizing-milk/for/oily-acne-prone-skin (this page)
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