# Perricone MD Vitamin C Ester Brightening Serum for dry skin

**Lovi Fit: High fit for dry skin.**
Dry Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/es/p/perricone-md/vitamin-c-ester-brightening-serum/for/dry-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Brand: [Perricone MD](https://lovi.care/skincare/es/brands/perricone-md)
Category: [Serums and treatments](https://lovi.care/skincare/es/best/serums)

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for dry skin; a few serums fit it even better.

## Why this fit

- Highly suitable for your dry skin as Sodium Hyaluronate and Squalane provide essential hydration and emollient benefits, addressing dryness and flakiness effectively.
- The inclusion of Vitamin C Ester and Ferulic Acid offers excellent brightening properties, enhancing your skin tone and radiance.
- The product is safe for your dry skin, with no risks of irritation due to the absence of harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/es/p/perricone-md/vitamin-c-ester-brightening-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/es/p/perricone-md/vitamin-c-ester-brightening-serum/for/dry-skin): High (this page)
- [Combination skin](https://lovi.care/skincare/es/p/perricone-md/vitamin-c-ester-brightening-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/es/p/perricone-md/vitamin-c-ester-brightening-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/es/p/perricone-md/vitamin-c-ester-brightening-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/es/p/perricone-md/vitamin-c-ester-brightening-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/es/p/perricone-md/vitamin-c-ester-brightening-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/es/p/perricone-md/vitamin-c-ester-brightening-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/es/p/perricone-md/vitamin-c-ester-brightening-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Ascorbic Acid Ester, Squalane, Ferulic Acid, Rosemary Leaf Extract, Sodium Hyaluronate

## What the research says

- Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/))
- Optimized transfersomes loaded with epigallocatechin-3-gallate and hyaluronic acid increased cell viability while reducing lipid peroxidation, intracellular ROS, and MMP expression in HaCaT cells, and exhibited higher skin permeation and deposition compared to plain EGCG. ([Drug Delivery, 2017](https://pubmed.ncbi.nlm.nih.gov/28155509/))
- A multiple W/O/W emulsion containing Rosmarinus officinalis L., Avena sativa L., and Linum usitatissimum L. extracts showed no irritant, phototoxic, inflammatory, or allergenic potential in human skin models and patch tests, establishing its safety as a cosmetic base. ([Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/34065623/))
- Hyaluronic acid extracts are safe and efficacious products for skin repair when used in tissue regeneration alone or in combination with herbal or Western medicine. ([Journal of Pharmacy & Pharmaceutical Sciences, 2015](https://pubmed.ncbi.nlm.nih.gov/25877441/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))
- Treatment with 14% ferulic acid and 12% l-ascorbic acid significantly reduced pigmentation and erythema while improving hydration and elasticity in 20 women with photoaged skin, with neither acid proving definitively more effective overall though ascorbic acid showed slightly greater skin lightening. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/34877760/))
- Combining fractional microneedle radiofrequency with a topical antioxidant serum significantly reduced wrinkle severity by 29.9% versus 18.0%, increased elasticity by 12.9% versus 2.3%, and improved aesthetic outcomes in 31 participants compared to radiofrequency and placebo. ([The Journal of Dermatological Treatment, 2025](https://pubmed.ncbi.nlm.nih.gov/40464749/))
- Pretreatment with a topical antioxidant mixture of vitamin C, ferulic acid, and phloretin attenuated ultraviolet-induced sunburn cell formation, thymine dimer formation, matrix metalloproteinase-9 expression, p53 protein expression, and the suppression of CD1a-expressing Langerhans cells in human skin compared to vehicle control. ([Journal of Cosmetic Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/19146606/))
- Topical application of rosemary essential oil-loaded lipid nanoparticles in gel vehicles significantly increased skin hydration compared to gels containing free oil, and increased elasticity to a lesser extent, in ten healthy volunteers. ([Pharmaceutics, 2017](https://pubmed.ncbi.nlm.nih.gov/29065483/))
- Topical application of a cream containing the NHE1 activator rosmarinic acid decreased skin surface pH and transepidermal water loss while increasing skin hydration in 50-60-year-old adult females compared to vehicle cream and no treatment. ([International Journal of Molecular Sciences, 2022](https://pubmed.ncbi.nlm.nih.gov/35409270/))
- An alcoholic extract of rosemary leaves, Rosm1, demonstrates strong antioxidant activity and inhibits oxidative alterations to skin surface lipids when evaluated in vitro and in vivo. ([International Journal of Tissue Reactions, 2000](https://pubmed.ncbi.nlm.nih.gov/10937349/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))

## What reviewers say

Users consistently report that the serum effectively brightens the complexion and smooths skin texture, often delivering a noticeable "glow" and reducing the appearance of dark spots. While the lightweight, citrus-scented formula is praised for quick absorption, some users with sensitive or dry skin experienced irritation and found it necessary to layer a heavy moisturizer on top.

- Liked: Brightens and glows (often mentioned)
- Liked: Smooths texture (often mentioned)
- Liked: Fades dark spots (sometimes noted)
- Liked: Lightweight absorption (sometimes noted)
- Liked: Pleasant scent (sometimes noted)
- Disliked: Drying formula (sometimes noted)
- Disliked: High price (sometimes noted)
- Disliked: Packaging issues (rarely noted)
- Disliked: Scent dislike (rarely noted)
- Disliked: Skin irritation (rarely noted)

## How to apply

- Apply this serum PM, starting 3×/week and working up to daily use as your skin adjusts.
- Place the serum after cleansing and toner, but right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on slightly damp skin to help lock in extra moisture.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Perricone MD Vitamin C Ester Brightening Serum a great fit for dry skin?

Perricone MD Vitamin C Ester Brightening Serum is a great fit for dry skin because sodium hyaluronate and squalane provide essential hydration to address dryness and flakiness effectively. Vitamin C ester and ferulic acid help brighten your skin tone and add radiance, and the formula is safe without harsh ingredients that might cause irritation.
Sources: [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Which ingredients make this serum a good fit for dry skin?

Sodium hyaluronate and squalane make this serum a great fit for dry skin by delivering essential moisture and tackling flakiness. Additionally, vitamin C ester and ferulic acid help brighten your skin tone and boost radiance.
Sources: [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### What does Ascorbic Acid do for dry skin?

Ascorbic Acid helps dry skin by improving moisture levels and hydration in the outer layer of the skin. It also helps support the skin barrier function to keep moisture locked in.
Sources: [Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/), [Skin Research and Technology, 2008](https://pubmed.ncbi.nlm.nih.gov/19159387/)

### What does Squalane do for dry skin?

Squalane helps keep dry skin soft and smooth by acting as a hydrating agent that locks in moisture and prevents water loss. It is unlikely to cause irritation and may protect the skin from damage while improving overall hydration.
Sources: [Advances in Food and Nutrition Research, 2012](https://pubmed.ncbi.nlm.nih.gov/22361190/), [Molecules, 2009](https://pubmed.ncbi.nlm.nih.gov/19169201/)

### Where does this serum go in a skincare routine for dry skin?

This treatment serum goes in the evening routine after cleansing and before moisturizing, though some serums may also be used in the morning or twice a day. Applying it at this time helps simplify your routine and provides extra safety around sun exposure.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying retinol at night and using this vitamin C serum in the morning, which helps brighten your skin without overloading it. Because dry skin needs gentle handling, using them at different times of day is unlikely to cause irritation.

### How often should I use this serum?

You can use this serum in your evening routine, applying it after cleansing and before moisturizing. It is generally safe for daily use on dry skin, helping to brighten your skin tone and provide essential hydration without irritation.

### Can this serum clog pores, cause breakouts or purging for dry skin?

This serum is unlikely to clog pores or cause breakouts for dry skin, as its hydrating ingredients help keep the skin smooth and balanced. While reviewers occasionally mention dryness, the formula's gentle ingredients are generally well-tolerated without causing irritation.
Sources: [Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/34065623/), [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Is this serum fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (benzyl alcohol, parfum, limonene, linalool, citral, and citronellol). Behenyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for dry skin

- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/es/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/dry-skin) — Superior fit — €57.00 at Amazon
- [ma:nyo Bifida Biome Complex Ampoule](https://lovi.care/skincare/es/p/ma-nyo/bifida-biome-complex-ampoule/for/dry-skin) — Superior fit — €18.50 at Amazon
- [Augustinus Bader The Serum](https://lovi.care/skincare/es/p/augustinus-bader/the-serum/for/dry-skin) — Superior fit — €333.00 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/es/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — €8.85 at Amazon
- Hydrating Toner: [Paula's Choice Resist Advanced Replenishing Toner](https://lovi.care/skincare/es/p/paula-s-choice/advanced-replenishing-toner/for/dry-skin) — Superior fit — €34.00 at Amazon
- Moisturizer: [d'Alba First Spray Serum](https://lovi.care/skincare/es/p/d-alba/first-spray-serum/for/dry-skin) — Superior fit — €16.99 at Amazon

## Where to buy

- Amazon.de: €74.90 (https://www.amazon.de/dp/B07GVS3XT3?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- Lookfantastic: €62.40 (https://www.lookfantastic.es/p/perricone-md-vitamin-c-ester-brightening-serum/13033787/)
- Notino: €141.00 (https://www.notino.es/perricone-md/vitamin-c-ester-brightening-complex-20-serum-iluminador-para-el-rostro/p-16232218/)
Prices checked 17 Oct – 5 Nov 2026.

## Ingredients

Water, Tetrahexyldecyl Ascorbate, Caprylyl Methicone, Hydrogenated Lecithin, Behenyl Alcohol, Benzyl Alcohol, Squalane, Rosmarinus Officinalis Leaf Extract Rosemary Leaf Extract, Ferulic Acid, Jojoba Seed Oil, Sodium Hyaluronate, Polysorbate 20, Xanthan Gum, Beta-Glucan, Parfum, Sorbitol, Limonene, Stearyl Glycyrrhetinate, Disodium Edta, Palm Oil, Tocotrienols, Linalool, Tocopherol, Citral, Citronellol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/perricone-md/vitamin-c-ester-brightening-serum/for/dry-skin
- United Kingdom: https://lovi.care/skincare/uk/p/perricone-md/vitamin-c-ester-brightening-serum/for/dry-skin
- Ireland: https://lovi.care/skincare/ie/p/perricone-md/vitamin-c-ester-brightening-serum/for/dry-skin
- Germany: https://lovi.care/skincare/de/p/perricone-md/vitamin-c-ester-brightening-serum/for/dry-skin
- France: https://lovi.care/skincare/fr/p/perricone-md/vitamin-c-ester-brightening-serum/for/dry-skin
- Italy: https://lovi.care/skincare/it/p/perricone-md/vitamin-c-ester-brightening-serum/for/dry-skin
- Netherlands: https://lovi.care/skincare/nl/p/perricone-md/vitamin-c-ester-brightening-serum/for/dry-skin
- Spain: https://lovi.care/skincare/es/p/perricone-md/vitamin-c-ester-brightening-serum/for/dry-skin (this page)
- Canada: https://lovi.care/skincare/ca/p/perricone-md/vitamin-c-ester-brightening-serum/for/dry-skin
- Australia: https://lovi.care/skincare/au/p/perricone-md/vitamin-c-ester-brightening-serum/for/dry-skin
- Singapore: https://lovi.care/skincare/sg/p/perricone-md/vitamin-c-ester-brightening-serum/for/dry-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/perricone-md/vitamin-c-ester-brightening-serum/for/dry-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/perricone-md/vitamin-c-ester-brightening-serum/for/dry-skin