# Perricone MD Cold Plasma Plus+ Sub-D/Neck for dry sensitive skin

**Lovi Fit: High fit for dry sensitive skin.**
Dry Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/es/p/perricone-md/cold-plasma-plus-sub-d-neck/for/dry-sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Brand: [Perricone MD](https://lovi.care/skincare/es/brands/perricone-md)
Category: [Sunscreens and SPF moisturizers](https://lovi.care/skincare/es/best/sunscreens)

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for dry sensitive skin; a few sunscreens fit it even better.

## Why this fit

- Highly suitable for your dry and sensitive skin, as Glycerin and Hydrogenated Lecithin provide essential hydration and barrier support, while Bisabolol calms irritation. Tetrahexyldecyl Ascorbate and Thioctic Acid offer antioxidant benefits, further protecting your skin.
- The formula includes Ethylhexyl Methoxycrylene for excellent UV protection, which is beneficial for maintaining skin health and preventing dryness-induced sensitivity.
- This product is safe for your skin, featuring a gentle formulation with soothing Bisabolol and no harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/es/p/perricone-md/cold-plasma-plus-sub-d-neck/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/es/p/perricone-md/cold-plasma-plus-sub-d-neck/for/dry-skin): Superior
- [Combination skin](https://lovi.care/skincare/es/p/perricone-md/cold-plasma-plus-sub-d-neck/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/es/p/perricone-md/cold-plasma-plus-sub-d-neck/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/es/p/perricone-md/cold-plasma-plus-sub-d-neck/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/es/p/perricone-md/cold-plasma-plus-sub-d-neck/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/es/p/perricone-md/cold-plasma-plus-sub-d-neck/for/mature-skin): Superior
- [Dry sensitive skin](https://lovi.care/skincare/es/p/perricone-md/cold-plasma-plus-sub-d-neck/for/dry-sensitive-skin): High (this page)
- [Oily acne-prone skin](https://lovi.care/skincare/es/p/perricone-md/cold-plasma-plus-sub-d-neck/for/oily-acne-prone-skin): High

## Key ingredients

Dmae, Niacinamide, Tetrahexyldecyl Ascorbate, Acetyl Tetrapeptide-9, Glycerin

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Daily application of 3% DMAE facial gel for 16 weeks safely and efficaciously mitigates forehead lines and periorbital fine wrinkles, improves lip shape and fullness and overall aging skin appearance, and increases skin firmness compared to placebo. ([American Journal of Clinical Dermatology, 2005](https://pubmed.ncbi.nlm.nih.gov/15675889/))
- A gel containing 3% 2-dimethylaminoethanol (DMAE) increased skin firmness, demonstrated by increased shear wave velocity in 30 volunteers compared to a formulation without DMAE. ([Skin Research and Technology, 2002](https://pubmed.ncbi.nlm.nih.gov/12236885/))
- A DMAE-based formulation increased dermal and collagen fiber thickness in hairless mice and enhanced stratum corneum water content in human forearm skin compared to control formulations, without significantly modifying mechanical properties. ([Die Pharmazie, 2009](https://pubmed.ncbi.nlm.nih.gov/20095140/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))

## What reviewers say

Based on a very large amount of data, users frequently report visible improvements in skin texture and firmness along the jawline and neck, describing the skin as smoother and more hydrated. A significant number of reviewers consistently complain about a strong, unpleasant scent often compared to pickles or fish, and some experience issues with the product pilling under makeup.

- Disliked: Unpleasant smell (mostly mentioned)
- Liked: Improves skin texture (often mentioned)
- Liked: Visibly tightens and firms (often mentioned)
- Liked: Hydrating formula (sometimes noted)
- Liked: Lightweight and absorbent (sometimes noted)
- Disliked: High price point (sometimes noted)
- Disliked: Caused irritation (rarely noted)
- Disliked: Pilling or flaking (rarely noted)

## How to apply

- Use this moisturizing sunscreen daily in your morning routine. Reapply every two hours if you are staying outdoors.
- Apply this product at the very end of your morning routine right after your regular moisturizer.
- Gently pat a nickel-sized amount of the moisturizing sunscreen evenly across your face and neck.
- Apply this product onto clean, dry skin before you go outside into the sun.
- Avoid the immediate eye area and do a patch test before your first use to check for sensitivity.
- Video: https://storage.pora.ai/53e9a436d82fca2a189dd08aa21de2fd.mp4

## Questions and answers

### What makes Perricone MD Sub-D/Neck a great fit for dry sensitive skin?

This product is a great fit because glycerin and hydrogenated lecithin bring essential hydration and barrier support, while bisabolol calms irritation. It also helps protect your skin with antioxidants and provides UV protection to prevent dryness-induced sensitivity.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this cream a good fit for dry sensitive skin?

Glycerin and hydrogenated lecithin make this cream a great fit by providing essential hydration and barrier support for dry skin. Bisabolol helps calm irritation, while tetrahexyldecyl ascorbate and thioctic acid offer antioxidant protection.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does DMAE do for dry sensitive skin?

DMAE helps make skin feel firmer and smoother, but it is unlikely to be a good fit for dry sensitive skin on its own. Because dry sensitive skin easily gets irritated, a product for this skin type needs gentle, soothing ingredients and deep moisturizers like hyaluronic acid or ceramides to keep skin soft and comfortable.
Sources: [American Journal of Clinical Dermatology, 2005](https://pubmed.ncbi.nlm.nih.gov/15675889/), [Skin Research and Technology, 2002](https://pubmed.ncbi.nlm.nih.gov/12236885/)

### What does Niacinamide do for dry sensitive skin?

Niacinamide helps dry sensitive skin by calming irritation and keeping moisture locked in so your face feels soft and smooth. It works to build up your skin barrier and calm redness while being very gentle and unlikely to cause irritation.
Sources: [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/), [International Journal of Pharmaceutics, 2013](https://pubmed.ncbi.nlm.nih.gov/23220080/)

### Where does this cream go in a skincare routine for dry sensitive skin?

This moisturizing spf goes in the morning routine as the final step after your cleanser and soothing toner. It is a great fit for your dry sensitive skin because ingredients like glycerin and hydrogenated lecithin provide essential hydration and barrier support while soothing bisabolol calms irritation.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/)

### Can I use this cream with retinol, and in what order?

You can use this moisturizing SPF in your morning routine after cleansing and a soothing toner, while keeping retinol for your evening routine. This safe formula helps protect your skin from UV rays and provides essential hydration, making it a great fit to use alongside your retinol regimen.

### How often should I use this cream?

You can use this moisturizing spf every morning as part of your routine. Daily application helps protect your skin from the sun while keeping it soft and comfortable.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this cream clog pores, cause breakouts or purging for dry sensitive skin?

This cream is unlikely to clog pores or cause breakouts for dry sensitive skin, as it features a gentle formula without harsh ingredients. It also helps calm irritation with soothing bisabolol.

### Is this cream fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (benzyl alcohol).

## Alternatives for dry sensitive skin

- [Purito Daily Soft Touch Sunscreen](https://lovi.care/skincare/es/p/purito/daily-soft-touch-sunscreen/for/dry-sensitive-skin) — Superior fit — €12.98 at Amazon
- [innisfree Daily Sensitive Sunscreen](https://lovi.care/skincare/es/p/innisfree/daily-sensitive-sunscreen/for/dry-sensitive-skin) — High fit — €23.58 at Lookfantastic

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/es/p/cerave/hydrating-facial-cleanser/for/dry-sensitive-skin) — Superior fit — €8.85 at Amazon
- Soothing Toner: [SKIN1004 Centella Asiatica Toning Toner](https://lovi.care/skincare/es/p/skin1004/centella-asiatica-toning-toner/for/dry-sensitive-skin) — Superior fit — €23.99 at Amazon
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/es/p/missha/ultra-hyalon-cleansing-cream/for/dry-sensitive-skin) — Superior fit — €10.97 at Amazon

## Where to buy

- Amazon.de: €122.00 (https://www.amazon.de/dp/B0862RV8F5?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- Notino: €132.10 (https://www.notino.es/perricone-md/cold-plasma-plus-neck-chest-crema-reafirmante-para-cuello-y-escote/p-16069906/)
Prices checked 17 Oct – 6 Nov 2026.

## Ingredients

Water, Dimethicone, Cyclopentasiloxane, Glycerin, Niacinamide, Ethylhexyl Methoxycrylene, Pentylene Glycol, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Polyester-8, Polyglyceryl-3 Polydimethylsiloxyethyl Dimethicone, Tetrahexyldecyl Ascorbate, Thioctic Acid, Acetyl Tetrapeptide-9, Diethylhexyl Syringylidenemalonate, Hydrogenated Lecithin, Bisabolol, Xanthan Gum, Hydrogenated Phosphatidylcholine, Mannitol, Benzyl Alcohol, Stearic Acid, Isohexadecane, Polysilicone-11, Polysorbate 60, Sorbitan Isostearate, Caprylic Capric Triglyceride, Phenoxyethanol, Potassium Sorbate, Sodium Benzoate, Aluminum Hydroxide
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/perricone-md/cold-plasma-plus-sub-d-neck/for/dry-sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/perricone-md/cold-plasma-plus-sub-d-neck/for/dry-sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/perricone-md/cold-plasma-plus-sub-d-neck/for/dry-sensitive-skin
- Germany: https://lovi.care/skincare/de/p/perricone-md/cold-plasma-plus-sub-d-neck/for/dry-sensitive-skin
- France: https://lovi.care/skincare/fr/p/perricone-md/cold-plasma-plus-sub-d-neck/for/dry-sensitive-skin
- Italy: https://lovi.care/skincare/it/p/perricone-md/cold-plasma-plus-sub-d-neck/for/dry-sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/perricone-md/cold-plasma-plus-sub-d-neck/for/dry-sensitive-skin
- Spain: https://lovi.care/skincare/es/p/perricone-md/cold-plasma-plus-sub-d-neck/for/dry-sensitive-skin (this page)
- Canada: https://lovi.care/skincare/ca/p/perricone-md/cold-plasma-plus-sub-d-neck/for/dry-sensitive-skin
- Australia: https://lovi.care/skincare/au/p/perricone-md/cold-plasma-plus-sub-d-neck/for/dry-sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/perricone-md/cold-plasma-plus-sub-d-neck/for/dry-sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/perricone-md/cold-plasma-plus-sub-d-neck/for/dry-sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/perricone-md/cold-plasma-plus-sub-d-neck/for/dry-sensitive-skin