# Peach & Lily Glass Skin Refining Serum for acne-prone skin

**Lovi Fit: Superior fit for acne-prone skin.**
Combination Skin Fit: Superior · Effectiveness: Superior · Safety: Excellent.

Page: https://lovi.care/skincare/es/p/peach-and-lily/glass-skin-refining-serum/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Brand: [Peach & Lily](https://lovi.care/skincare/es/brands/peach-and-lily)
Category: [Serums and treatments](https://lovi.care/skincare/es/best/serums)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best serums for acne-prone skin.

## Why this fit

- Excellent suitability for your combination skin and acne concerns is provided by niacinamide and madecassoside, which effectively regulate oil production and target inflammation for clearer, smoother skin. Multiple forms of hyaluronic acid further enhance hydration and plumpness, creating a balanced and refined complexion.
- The inclusion of saccharide isomerate and beta-glucan offers additional soothing and humectant benefits, supporting overall skin health and comfort.
- The product is safe for your skin, with no risks of irritation due to the absence of harsh ingredients and the presence of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/es/p/peach-and-lily/glass-skin-refining-serum/for/oily-skin): Superior
- [Dry skin](https://lovi.care/skincare/es/p/peach-and-lily/glass-skin-refining-serum/for/dry-skin): Superior
- [Combination skin](https://lovi.care/skincare/es/p/peach-and-lily/glass-skin-refining-serum/for/combination-skin): Superior
- [Sensitive skin](https://lovi.care/skincare/es/p/peach-and-lily/glass-skin-refining-serum/for/sensitive-skin): Superior
- [Acne-prone skin](https://lovi.care/skincare/es/p/peach-and-lily/glass-skin-refining-serum/for/acne-prone-skin): Superior (this page)
- [Skin with dark spots](https://lovi.care/skincare/es/p/peach-and-lily/glass-skin-refining-serum/for/dark-spots): Superior
- [Mature skin](https://lovi.care/skincare/es/p/peach-and-lily/glass-skin-refining-serum/for/mature-skin): Superior
- [Dry sensitive skin](https://lovi.care/skincare/es/p/peach-and-lily/glass-skin-refining-serum/for/dry-sensitive-skin): Superior
- [Oily acne-prone skin](https://lovi.care/skincare/es/p/peach-and-lily/glass-skin-refining-serum/for/oily-acne-prone-skin): Superior

## Key ingredients

Niacinamide, Prunus Persica Extract, Sodium Hyaluronate, Madecassoside, Acetyl Octapeptide-3

## What the research says

- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- A novel moisturizer containing saccharide isomerate accelerates skin barrier recovery, improves hydration, reduces erythema, and alleviates discomfort compared to a control moisturizer following intense pulsed light treatment in subjects with skin aging. ([The Journal of Dermatological Treatment, 2025](https://pubmed.ncbi.nlm.nih.gov/41211697/))
- Skin care regimens containing beta-glucan improved hemoglobin index, skin hydration, and transepidermal water loss compared to vehicle control in 20 patients undergoing fractional laser therapy. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33128496/))
- A combination cream of stimu-tex AS and saccharide isomerate reduced erythema, increased skin capacitance, and reduced transepidermal water loss compared to placebo in 20 subjects after fractional CO2 laser procedure without causing serious adverse events. ([Lasers in Medical Science, 2025](https://pubmed.ncbi.nlm.nih.gov/41134387/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Fresh unripe peach extract significantly improved mRNA levels and partial localization of collagen type XVIII in UV-B irradiated human 3D skin models. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30548159/))
- Prunus persica leaf extract loaded in solid lipid nanoparticles demonstrated non-toxicity, antioxidant activity, and anti-aging efficacy against UV-induced photoaging in a mouse model. ([Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/33809166/))
- Topical application of Prunus persica flower extract and its active constituent multiflorin B inhibited UVB-induced erythema in guinea pigs and ear edema in mice in a dose-dependent manner. ([Journal of Cosmetic Science, 2002](https://pubmed.ncbi.nlm.nih.gov/11917253/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))

## What reviewers say

This serum is praised for delivering a dewy, smooth, and translucent "glass skin" appearance with a lightweight, fast-absorbing formula. It is frequently noted for its ability to calm redness and fade dark spots, and is generally considered gentle. However, a small number of users report breakouts, possibly due to niacinamide sensitivity, and some find it ineffective or not hydrating enough.

- Liked: Glass skin glow (mostly mentioned)
- Liked: Lightweight, absorbs fast (mostly mentioned)
- Liked: Calms redness (often mentioned)
- Liked: Gentle, sensitive skin (often mentioned)
- Liked: Fades dark spots (sometimes noted)
- Disliked: High price point (sometimes noted)
- Disliked: Lack of results (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Not hydrating (rarely noted)
- Disliked: Texture issues (rarely noted)

## How to apply

- Use your serum as part of your PM routine and start 3x/week before working up to daily use.
- Apply this treatment after cleansing and toner, and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the product on clean, dry skin to help manage your breakouts safely.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Peach & Lily Glass Skin Refining Serum one of the best fits for acne-prone skin?

This serum is one of the best fits because niacinamide and madecassoside regulate oil production and calm redness, helping you get clearer, smoother skin. Multiple forms of hyaluronic acid, beta-glucan, and saccharide isomerate add deep hydration and soothing comfort without causing irritation.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [The Journal of Dermatological Treatment, 2025](https://pubmed.ncbi.nlm.nih.gov/41211697/)

### Which ingredients make this serum a good fit for acne-prone skin?

Niacinamide and madecassoside make this serum a great fit because they help regulate oil production and calm redness for clearer, smoother skin. The formula is safe for your skin and is unlikely to cause irritation due to its soothing ingredients.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### What does Niacinamide do for acne-prone skin?

Niacinamide helps acne-prone skin by reducing both inflamed and uninflamed breakouts and calming redness. It is also very helpful for keeping oily skin balanced by cutting down on excess oil production, and it is well tolerated by most people.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38299457/), [Cureus, 2024](https://pubmed.ncbi.nlm.nih.gov/38725769/)

### What does Peach Extract do for acne-prone skin?

Peach Extract helps clear up acne-prone skin by reducing pimples and calming redness. It is unlikely to irritate, as studies show it fights bacteria and lowers inflammation safely.
Sources: [Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30414245/), [The Journal of Dermatological Treatment, 2021](https://pubmed.ncbi.nlm.nih.gov/31424962/)

### Where does this serum go in a skincare routine for acne-prone skin?

This serum goes in the evening routine after cleansing and toning, and before moisturizing. Putting treatments in the evening keeps things simple and adds extra safety around sun exposure, though some may also be used in the morning or twice a day.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol, applying this treatment first to calm the skin and keep it hydrated. Niacinamide and madecassoside help reduce irritation, making the routine very safe and well tolerated for acne-prone skin.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### How often should I use this serum?

This treatment fits your acne-prone skin exceptionally well and can be used in the evening as part of your routine. It helps calm redness and manage oil production for clearer, smoother skin without irritation.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### Can this serum clog pores, cause breakouts or purging for acne-prone skin?

This serum is an exceptional fit for acne-prone skin because niacinamide and madecassoside help calm redness and keep oil production balanced for clearer skin. It has a great safety profile with soothing ingredients, making it unlikely to clog pores or cause irritation, though a few reviewers have reported breakouts.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for acne-prone skin

- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/es/p/skinceuticals/c-e-ferulic/for/acne-prone-skin) — Superior fit — €169.99 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/es/p/neogen-dermalogy/real-vitamin-c-serum/for/acne-prone-skin) — Superior fit — €29.76 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/es/p/skin1004/probio-cica-intensive-ampoule/for/acne-prone-skin) — High fit — €21.99 at Amazon

## Pairs well with

- Cleanser: [B.LAB Matcha Hydrating Foam Cleanser](https://lovi.care/skincare/es/p/b-lab/matcha-hydrating-foam-cleanser/for/acne-prone-skin) — Superior fit — €11.99 at Amazon
- Hydrating Toner: [Paula's Choice Resist Advanced Replenishing Toner](https://lovi.care/skincare/es/p/paula-s-choice/advanced-replenishing-toner/for/acne-prone-skin) — Superior fit — €34.00 at Amazon
- Moisturizer: [SKIN1004 Centella Cream](https://lovi.care/skincare/es/p/skin1004/centella-cream/for/acne-prone-skin) — Superior fit — €17.49 at Amazon

## Where to buy

No store in Spain has a checked price for this product, so the page shows none.

## Ingredients

Water, Propanediol, Butylene Glycol, Niacinamide, 1,2-Hexanediol, Prunus Persica Fruit Extract, Dioscorea Japonica Root Extract, Sodium Hyaluronate, Adenosine, Hydrolyzed Sodium Hyaluronate, Madecassoside, Hydrolyzed Hyaluronic Acid, Sodium Acetylated Hyaluronate, Acetyl Octapeptide-3, Ethylhexylglycerin, Hydrolyzed Corn Starch, Sodium Carbomer, Beta-Glucan, Saccharide Isomerate, Phytic Acid, Sucrose, Asiaticoside, Caprylyl Glycol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/peach-and-lily/glass-skin-refining-serum/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/peach-and-lily/glass-skin-refining-serum/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/peach-and-lily/glass-skin-refining-serum/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/peach-and-lily/glass-skin-refining-serum/for/acne-prone-skin
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- Netherlands: https://lovi.care/skincare/nl/p/peach-and-lily/glass-skin-refining-serum/for/acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/peach-and-lily/glass-skin-refining-serum/for/acne-prone-skin (this page)
- Canada: https://lovi.care/skincare/ca/p/peach-and-lily/glass-skin-refining-serum/for/acne-prone-skin
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- Singapore: https://lovi.care/skincare/sg/p/peach-and-lily/glass-skin-refining-serum/for/acne-prone-skin
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