# PCA SKIN Rejuvenating Serum for dry skin

**Lovi Fit: Average fit for dry skin.**
Dry Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/es/p/pca-skin/rejuvenating-serum/for/dry-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Brand: [PCA SKIN](https://lovi.care/skincare/es/brands/pca-skin)
Category: [Serums and treatments](https://lovi.care/skincare/es/best/serums)

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for dry skin; other serums fit it better.

## Why this fit

- Offers moderate suitability for your dry skin as gluconolactone and niacinamide provide mild exfoliation and improve skin tone, while glycerin and sodium PCA offer hydration. The formula lacks sufficient emollient ingredients like squalane and rice bran wax to fully address dryness.
- The presence of Bisabolol and Aloe Barbadensis Leaf Juice ensures no risks of irritation for your dry skin, as they are soothing ingredients.
- This product offers general skincare benefits, such as hydration, cleansing, or soothing, so that you would notice them, but the benefits are irrelevant or mostly supportive for your dry or flaky skin.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/es/p/pca-skin/rejuvenating-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/es/p/pca-skin/rejuvenating-serum/for/dry-skin): Average (this page)
- [Combination skin](https://lovi.care/skincare/es/p/pca-skin/rejuvenating-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/es/p/pca-skin/rejuvenating-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/es/p/pca-skin/rejuvenating-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/es/p/pca-skin/rejuvenating-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/es/p/pca-skin/rejuvenating-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/es/p/pca-skin/rejuvenating-serum/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/es/p/pca-skin/rejuvenating-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Niacinamide, Glutathione, Squalane, Epigallocatechin Gallate, Aloe Barbadensis Leaf Juice

## What the research says

- Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Glutathione amino acid precursors effectively increase cellular glutathione levels, reducing oxidative stress, ATP depletion, and DNA damage in human keratinocytes, clinical subjects, and ex vivo skin compared to controls. ([Journal of the European Academy of Dermatology and Venereology, 2024](https://pubmed.ncbi.nlm.nih.gov/38189670/))
- Topical oxidized glutathione significantly decreases the skin melanin index and improves moisture content, smoothness, wrinkle formation, and elasticity compared to placebo in healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/25378941/))
- Topical glutathione improves hyperpigmentation, reduces ultraviolet-induced erythema and wrinkles, decreases transepidermal water loss, and enhances antioxidant capacity. ([The Journal of Clinical and Aesthetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/41416233/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))
- Topical green tea extract significantly improved clinical symptoms, tear breakup times, and meibomian gland health compared to standard treatment in patients with dry eye and Meibomian Gland Dysfunction. ([Journal of Clinical and Diagnostic Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28384900/))
- Topical low-dose green tea extract reduces UVB-induced p53 expression and apoptosis in human skin keratinocytes compared to placebo. ([Experimental Dermatology, 2009](https://pubmed.ncbi.nlm.nih.gov/18631247/))
- An anti-acne hydrogel containing Aloe barbadensis, Garcinia mangostana, and Camellia sinensis extracts showed superior antiacne and antiblotch activities compared to 1% clindamycin gel in sixty subjects with mild-moderate acne. ([Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/31239743/))
- A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo. ([Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/))
- Topical aloe vera gel significantly accelerated split-thickness skin graft donor-site healing compared to placebo in 12 patients, but showed no significant difference in pain relief. ([Plastic and Reconstructive Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29649056/))
- Topical application of Aloe vera cream reduced postoperative pain at rest and during defecation, accelerated wound healing at two weeks, and decreased analgesic requirements in patients after open hemorrhoidectomy compared to placebo. ([Journal of Alternative and Complementary Medicine, 2010](https://pubmed.ncbi.nlm.nih.gov/20569031/))

## Why other serums fit dry skin better

- A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/))
- Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days. ([Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/))

## What reviewers say

This product is highly praised for improving skin texture, reducing fine lines, and providing a radiant glow. Users frequently mention its lightweight, fast-absorbing formula. Some users with sensitive skin find the alcohol-heavy base to be drying or irritating.

- Liked: Improves radiance (mostly mentioned)
- Liked: Lightweight texture (often mentioned)
- Liked: Reduces fine lines (often mentioned)
- Liked: Refreshing experience (sometimes noted)
- Disliked: Drying formula (sometimes noted)
- Disliked: High price (sometimes noted)
- Disliked: Irritating ingredients (rarely noted)
- Disliked: Lack of results (rarely noted)

## How to apply

- Apply this serum PM, starting 3×/week and working up to daily use as your skin adjusts.
- Place the serum after cleansing and toner, but right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on slightly damp skin to help lock in extra moisture.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does PCA SKIN Rejuvenating Serum work for dry skin?

PCA SKIN Rejuvenating Serum offers moderate suitability for dry skin as it provides mild exfoliation and hydration, though it lacks sufficient soft ingredients to fully address dryness. A treatment for dry skin needs rich, nourishing ingredients that provide deep hydration and support the skin barrier.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for dry skin?

Glycerin, sodium PCA, squalane, niacinamide, and gluconolactone make this serum a fit for dry skin by offering hydration and mild exfoliation, though this product lacks enough heavy smoothing ingredients to fully address dryness. Dry skin needs rich hydrating ingredients like ceramides, propolis, or plant oils, along with soothing agents, to lock in moisture and deeply nourish.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/)

### What does Niacinamide do for dry skin?

Niacinamide helps dry skin by strengthening the skin barrier, increasing hydration, and reducing water loss. It supports ceramide production and helps keep the surface smooth and calm. This ingredient tends to be very well tolerated and is unlikely to irritate dry skin.
Sources: [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/), [Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/42108609/)

### What does Glutathione do for dry skin?

Glutathione helps dry skin by improving moisture levels and smoothness while keeping the skin barrier strong against daily stress. Topical application of glutathione may also reduce water loss through the skin, helping your face feel softer and more hydrated.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/25378941/), [The Journal of Clinical and Aesthetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/41416233/)

### Where does it go in a skincare routine for dry skin?

This treatment goes in the evening routine after cleansing and before moisturizing. Dry skin like this needs extra rich hydrators and heavy smoothing ingredients like shea butter or botanical oils to fully soften tight spots.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying this treatment first and following with your retinol at night. Because this product lacks enough heavy moisturizing ingredients to fully protect dry skin, you may want to follow with a rich cream to prevent dryness.

### How often should I use it?

You can use this treatment in the evening as part of your routine. A product of this type needs richer softening ingredients and heavy moisturizing oils to truly comfort dry skin.

### Can this serum clog pores, cause breakouts or purging for dry skin?

This serum is unlikely to clog pores or cause breakouts for dry skin, though some users note a drying formula. A product of this type needs richer softening ingredients like plant oils or butters to properly comfort dry skin.

### Is it fragrance-free and alcohol-free?

It has no fragrance and contains drying alcohol (sd alcohol 40-b).

## Alternatives for dry skin

- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/es/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/dry-skin) — Superior fit — €57.00 at Amazon
- [ma:nyo Bifida Biome Complex Ampoule](https://lovi.care/skincare/es/p/ma-nyo/bifida-biome-complex-ampoule/for/dry-skin) — Superior fit — €18.50 at Amazon
- [Augustinus Bader The Serum](https://lovi.care/skincare/es/p/augustinus-bader/the-serum/for/dry-skin) — Superior fit — €333.00 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/es/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — €8.85 at Amazon
- Hydrating Toner: [Paula's Choice Resist Advanced Replenishing Toner](https://lovi.care/skincare/es/p/paula-s-choice/advanced-replenishing-toner/for/dry-skin) — Superior fit — €34.00 at Amazon
- Moisturizer: [d'Alba First Spray Serum](https://lovi.care/skincare/es/p/d-alba/first-spray-serum/for/dry-skin) — Superior fit — €16.99 at Amazon

## Where to buy

No store in Spain has a checked price for this product, so the page shows none.

## Ingredients

Water, Sd Alcohol 40-B, Glycerin, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Gluconolactone, Polysorbate 20, Bisabolol, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Isomalt, Sodium Pca, Sodium Lactate, Sodium Benzoate, Caprylyl Glycol, 1,2-Hexanediol, Peppermint Oil, Tocopherol, Squalane, Glutathione, Grapefruit Peel Oil, Citrus Aurantium Dulcis Peel Oil, Phytosterols, Tropolone, Epigallocatechin Gallate, Camellia Oleifera Leaf Extract, Aminomethyl Propanol, Tocotrienols, Squalene, Rice Bran Wax, Aloe Barbadensis Leaf Juice, Urea, Niacinamide, Glycine, Fructose, Vitis Vinifera Fruit Cell Extract Grape Fruit Cell Extract, Lecithin, Inositol, Rh-Oligopeptide-1
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/pca-skin/rejuvenating-serum/for/dry-skin
- United Kingdom: https://lovi.care/skincare/uk/p/pca-skin/rejuvenating-serum/for/dry-skin
- Ireland: https://lovi.care/skincare/ie/p/pca-skin/rejuvenating-serum/for/dry-skin
- Germany: https://lovi.care/skincare/de/p/pca-skin/rejuvenating-serum/for/dry-skin
- France: https://lovi.care/skincare/fr/p/pca-skin/rejuvenating-serum/for/dry-skin
- Italy: https://lovi.care/skincare/it/p/pca-skin/rejuvenating-serum/for/dry-skin
- Netherlands: https://lovi.care/skincare/nl/p/pca-skin/rejuvenating-serum/for/dry-skin
- Spain: https://lovi.care/skincare/es/p/pca-skin/rejuvenating-serum/for/dry-skin (this page)
- Canada: https://lovi.care/skincare/ca/p/pca-skin/rejuvenating-serum/for/dry-skin
- Australia: https://lovi.care/skincare/au/p/pca-skin/rejuvenating-serum/for/dry-skin
- Singapore: https://lovi.care/skincare/sg/p/pca-skin/rejuvenating-serum/for/dry-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/pca-skin/rejuvenating-serum/for/dry-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/pca-skin/rejuvenating-serum/for/dry-skin