# Olay Retinol 24 Night Serum for oily acne-prone skin

**Lovi Fit: High fit for oily acne-prone skin.**
Oily Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/es/p/olay/retinol-24-night-serum/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Brand: [Olay](https://lovi.care/skincare/es/brands/olay)
Category: [Serums and treatments](https://lovi.care/skincare/es/best/serums)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for oily acne-prone skin; a few serums fit it even better.

## Why this fit

- Offers high suitability for your oily skin as niacinamide and retinol work to regulate sebum and cell turnover, addressing your concerns with acne, blemishes, and breakouts. Palmitoyl pentapeptide-4 and retinol also provide excellent treatment for minimizing fine lines and wrinkles.
- The formula offers general skincare benefits, such as hydration, with supportive benefits for acne, blemishes, and breakouts on oily skin due to the presence of Retinyl Propionate and Retinol in concentrations that promote cell turnover.
- The safety profile is excellent, with no risks of irritation for your oily skin due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/es/p/olay/retinol-24-night-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/es/p/olay/retinol-24-night-serum/for/dry-skin): Low
- [Combination skin](https://lovi.care/skincare/es/p/olay/retinol-24-night-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/es/p/olay/retinol-24-night-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/es/p/olay/retinol-24-night-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/es/p/olay/retinol-24-night-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/es/p/olay/retinol-24-night-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/es/p/olay/retinol-24-night-serum/for/dry-sensitive-skin): Low
- [Oily acne-prone skin](https://lovi.care/skincare/es/p/olay/retinol-24-night-serum/for/oily-acne-prone-skin): High (this page)

## Key ingredients

Retinol, Niacinamide, Palmitoyl Pentapeptide-4, Glycerin, Dimethicone

## What the research says

- Topical palmitoyl pentapeptide (pal-KTTKS) provided significant improvement versus placebo control in the reduction of wrinkles and fine lines in Caucasian female subjects. ([International Journal of Cosmetic Science, 2005](https://pubmed.ncbi.nlm.nih.gov/18492182/))
- Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging. ([The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/))
- Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle. ([International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/))
- Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity. ([Journal of Controlled Release, 2018](https://pubmed.ncbi.nlm.nih.gov/29604311/))
- Topical stabilized retinol treatment induced HAS gene expression and increased hyaluronic acid production in human skin in vitro, ex vivo, and in vivo compared to vehicle. ([Archives of Dermatological Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28247017/))
- Topical application of all-trans-retinol induced epidermal thickening and increased retinoid binding protein expression similar to all-trans-retinoic acid in normal human skin, but without causing significant erythema or measurable retinoic acid levels. ([The Journal of Investigative Dermatology, 1995](https://pubmed.ncbi.nlm.nih.gov/7561157/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Wearing an N95 mask alone compared to using dimethicone cream or hydrocolloid dressing caused more adverse skin reactions among 73 military health care workers, with no significant differences in fit test failure rates between groups. ([Military Medicine, 2024](https://pubmed.ncbi.nlm.nih.gov/38771104/))
- A dimethicone skin protectant lotion significantly decreased visual scoring and transepidermal water loss compared to vehicle control and SLS-only treated sites in 12 healthy humans exposed to sodium lauryl sulfate. ([Skin Research and Technology, 2000](https://pubmed.ncbi.nlm.nih.gov/11428946/))
- Treatment with a moisturizer containing dimethicone and glycerine increased epidermal thickness by 0.019 mm, improved barrier function by decreasing transepidermal water loss by 13%, decreased melanin intensity, and induced keratins 6 and 16 in fifteen women with moderately photoaged forearms. ([Clinical and Experimental Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17137484/))

## What reviewers say

Users consistently praise this serum for its gentle, non-drying formula that leaves skin feeling silky and hydrated, making it an excellent choice for retinol beginners. While many report noticeably smoother texture and a brighter complexion, some users note that deep wrinkle reduction takes significant time and the product can pill if layered incorrectly.

- Liked: Gentle & non-irritating (mostly mentioned)
- Liked: Smoother skin texture (mostly mentioned)
- Liked: Hydrating formula (often mentioned)
- Liked: Lightweight absorption (often mentioned)
- Liked: Brightening effect (sometimes noted)
- Disliked: Product pilling (sometimes noted)
- Disliked: Slow results (sometimes noted)
- Disliked: Packaging issues (rarely noted)
- Disliked: Price point (rarely noted)
- Disliked: Sticky residue (rarely noted)

## How to apply

- Could be used as part of your PM routine. Start 3 times a week and build up to daily use if your skin tolerates it well.
- Apply your serum after cleansing and toning, but before putting on your moisturizer.
- Gently press 2 to 3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on clean, dry skin to help manage your blemishes safely.
- Do a patch test before your first use and avoid the delicate eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Olay Retinol 24 a great fit for oily acne-prone skin?

Olay Retinol 24 Night Serum is a great fit because ingredients like niacinamide and retinol help balance oil and speed up cell renewal to keep breakouts under control. The formula also smooths out fine lines while keeping your skin hydrated and comfortable.
Sources: [International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/)

### Which ingredients make this serum a good fit for oily acne-prone skin?

Niacinamide and retinol make this serum a great fit for your oily acne-prone skin because they help regulate oil and skin cell renewal to clear up breakouts. Retinol and palmitoyl pentapeptide-4 also smooth out fine lines while keeping your skin safely comfortable.
Sources: [International Journal of Cosmetic Science, 2005](https://pubmed.ncbi.nlm.nih.gov/18492182/)

### What does Retinol do for oily acne-prone skin?

Retinol helps oily acne-prone skin by clearing up breakouts and smoothing the skin, though it may occasionally cause some mild scaling or stinging. This ingredient works by addressing the root causes of acne, making it a reliable choice for keeping pores clear and skin smooth.
Sources: [American Journal of Clinical Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30674002/), [Journal of Drugs in Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/30586483/)

### What does Niacinamide do for oily acne-prone skin?

Niacinamide helps balance oil production, calms redness, and is unlikely to irritate oily, acne-prone skin while improving blemishes. Clinical tests show it reduces excess oil and helps clear up both inflammatory and non-inflammatory acne breakouts.
Sources: [Journal of Cosmetic and Laser Therapy, 2006](https://pubmed.ncbi.nlm.nih.gov/16766489/), [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38299457/)

### Where does it go in a skincare routine for oily acne-prone skin?

Apply this serum in your evening routine after cleansing and toning, and before moisturizing. This timing helps protect your skin from sun sensitivity while allowing the active ingredients to work overnight.

### Can I use this serum with vitamin C, and in what order?

You can use this serum with vitamin C by applying your vitamin C in the morning and this serum at night to avoid overwhelming your skin. Using them at different times of day helps your skin handle both powerful ingredients safely while keeping breakouts and dark spots under control.
Sources: [American Family Physician, 2012](https://pubmed.ncbi.nlm.nih.gov/23062156/)

### How often should I use it?

Use this serum in your evening routine to keep your oily and acne-prone skin clear with minimal risk of irritation. Applying it at night helps regulate oil and supports skin renewal while avoiding daytime sun sensitivity.
Sources: [Facial Plastic Surgery, 2014](https://pubmed.ncbi.nlm.nih.gov/24488631/)

### Can this serum clog pores, cause breakouts or purging for oily acne-prone skin?

This serum is a great fit because retinol and niacinamide help regulate oil and clear out pores to calm breakouts. It has a very safe formula with no harsh ingredients, though retinol may cause some mild initial purging as skin cell turnover speeds up.
Sources: [International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/)

### Is it fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (benzyl alcohol).

## Alternatives for oily acne-prone skin

- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/es/p/neogen-dermalogy/real-vitamin-c-serum/for/oily-acne-prone-skin) — Superior fit — €29.76 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/es/p/neogen-dermalogy/real-vita-c-serum/for/oily-acne-prone-skin) — High fit — €29.76 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/es/p/skin1004/probio-cica-intensive-ampoule/for/oily-acne-prone-skin) — High fit — €21.99 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/es/p/cerave/foaming-facial-cleanser/for/oily-acne-prone-skin) — Superior fit — €20.50 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/es/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-acne-prone-skin) — Superior fit — €36.00 at Amazon
- SPF: [Dear, Klairs All-day Airy Sunscreen](https://lovi.care/skincare/es/p/dear-klairs/all-day-airy-sunscreen/for/oily-acne-prone-skin) — Superior fit — €21.00 at Amazon

## Where to buy

- Amazon.de: €19.99 (https://www.amazon.de/dp/B0852NGPQ5?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
Prices checked 5 Nov 2026.

## Ingredients

Water, Dimethicone, Glycerin, Retinyl Propionate, Caprylic Capric Triglyceride, Retinol, Palmitoyl Pentapeptide-4, Bht, Butylene Glycol, Dimethiconol, Niacinamide, Polysorbate 20, Laureth-4, Laureth-7, Disodium Edta, Dimethicone Crosspolymer, Polyacrylamide, Peg-100 Stearate, Titanium Dioxide, Mica, Tin Oxide, C13-14 Alkane, Dmdm Hydantoin, Iodopropynyl Butylcarbamate, Benzyl Alcohol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/olay/retinol-24-night-serum/for/oily-acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/olay/retinol-24-night-serum/for/oily-acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/olay/retinol-24-night-serum/for/oily-acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/olay/retinol-24-night-serum/for/oily-acne-prone-skin
- France: https://lovi.care/skincare/fr/p/olay/retinol-24-night-serum/for/oily-acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/olay/retinol-24-night-serum/for/oily-acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/olay/retinol-24-night-serum/for/oily-acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/olay/retinol-24-night-serum/for/oily-acne-prone-skin (this page)
- Canada: https://lovi.care/skincare/ca/p/olay/retinol-24-night-serum/for/oily-acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/olay/retinol-24-night-serum/for/oily-acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/olay/retinol-24-night-serum/for/oily-acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/olay/retinol-24-night-serum/for/oily-acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/olay/retinol-24-night-serum/for/oily-acne-prone-skin