# NEOCUTIS Bio Serum Firm for oily skin

**Lovi Fit: Average fit for oily skin.**
Oily Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/es/p/neocutis/bio-serum-firm/for/oily-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Brand: [NEOCUTIS](https://lovi.care/skincare/es/brands/neocutis)
Category: [Serums and treatments](https://lovi.care/skincare/es/best/serums)

This fit is calculated for the concerns frequently associated with oily skin: shine, enlarged pores, blackheads, and blemishes. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for oily skin; other serums fit it better.

## Why this fit

- Highly suitable for your oily skin, this serum contains Aminopropyl Ascorbyl Phosphate and Glycerin to provide antioxidant benefits and hydration, supporting overall skin health.
- The inclusion of Tetrapeptide-21 and Palmitoyl Tripeptide-1 Acetate offers moderate firming effects, promoting skin elasticity and reducing the appearance of fine lines.
- The product is safe for your skin, with no risks of irritation due to the absence of harsh ingredients and the presence of soothing components like Glycerin and Sodium Hyaluronate.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/es/p/neocutis/bio-serum-firm/for/oily-skin): Average (this page)
- [Dry skin](https://lovi.care/skincare/es/p/neocutis/bio-serum-firm/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/es/p/neocutis/bio-serum-firm/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/es/p/neocutis/bio-serum-firm/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/es/p/neocutis/bio-serum-firm/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/es/p/neocutis/bio-serum-firm/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/es/p/neocutis/bio-serum-firm/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/es/p/neocutis/bio-serum-firm/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/es/p/neocutis/bio-serum-firm/for/oily-acne-prone-skin): Average

## Key ingredients

Rejuvenating Growth Factor, Peptides, Sodium Hyaluronate, Acetyl Glucosamine, Aminopropyl Ascorbyl Phosphate

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants. ([Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/))
- A multi-modal methodology combining MALDI-MSI, in vivo RCM, echography, and histology revealed age-related decreases in extracellular matrix and epidermal-dermal junction proteins and undulation depth, while a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 improved subepidermal low-echogenic band thickness, density, and extracellular matrix structure compared to placebo. ([Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical 2% N-acetyl glucosamine reduced facial hyperpigmentation in an 8-week split-face clinical test, with an even greater effect observed when combined with 4% niacinamide. ([Journal of Cosmetic Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17348991/))
- N-acetyl-glucosamine-loaded nanostructured lipid carriers successfully delivered the hydrophilic agent through the skin and reduced melanin distribution in healthy volunteers. ([Advanced Pharmaceutical Bulletin, 2016](https://pubmed.ncbi.nlm.nih.gov/28101465/))
- Topical cosmetic products containing hyaluronic acid, N-acetyl glucosamine, and gamma-amino butyric acid improved skin hydration by 24.28% to 33.60%, elasticity by 11.98%, and skin lightening by 5.26% over 2 months in 20 female participants. ([Journal of Cosmetic and Laser Therapy, 2019](https://pubmed.ncbi.nlm.nih.gov/30040516/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))

## What reviewers say

Users frequently report significant improvements in skin texture and hydration, with many experiencing smoother skin and a reduction in fine lines and increased firmness within the first week. The product is also often praised for its hydrating and plumping effects, leaving skin with a dewy glow and appearing more radiant. While a substantial number of users find the anti-aging results to be worth the cost, the high price point is a commonly mentioned drawback.

- Disliked: High price (mostly mentioned)
- Liked: Hydrating and Plumping (often mentioned)
- Liked: Improves Skin Texture (often mentioned)
- Liked: Reduces Fine Lines (often mentioned)
- Liked: Fast Results (sometimes noted)
- Liked: Gentle on Skin (sometimes noted)
- Disliked: Irritation/Reactions (rarely noted)
- Disliked: Lack of Results (rarely noted)
- Disliked: Product Pilling (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week and build up to daily use if your skin tolerates it well.
- Apply the serum after cleansing and toning, but right before your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin. Let it absorb ⏱ for a minute before applying the next product.
- Apply the serum on clean and dry skin since your skin is not sensitive and you want to target oily shine. This helps control excess oil throughout the night.
- Avoid the delicate eye area and do a patch test before using the serum for the very first time.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Neocutis Bio Serum Firm work for oily skin?

Neocutis Bio Serum Firm works moderately well for oily skin, providing hydration and firming benefits without causing irritation. However, a product of this type needs ingredients like niacinamide, zinc PCA, or ferulic acid to effectively control excess oil and manage shine for this skin type.
Sources: [Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for oily skin?

Aminopropyl Ascorbyl Phosphate and Glycerin make this serum a good fit for oily skin by providing antioxidant benefits and keeping the face hydrated without causing irritation. To be an even better fit for this skin type, a treatment needs ingredients like niacinamide and zinc PCA to control shine and manage excess oil.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Growth Factor do for oily skin?

Growth factor helps balance and repair oily skin while supporting a smooth and calm texture. This type of skin needs lightweight hydrators and soothing ingredients that manage excess oil without clogging pores.

### What do Peptides do for oily skin?

Peptides help support skin health and may improve the look of oily skin, but this type of skin needs formulas with ingredients that balance oil production and keep pores clear.
Sources: [Advanced Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39783908/), [International Journal of Molecular Sciences, 2025](https://pubmed.ncbi.nlm.nih.gov/40565185/)

### Where does it go in a skincare routine for oily skin?

This treatment goes in the evening routine after cleansing and before your moisturizer. Treatments with active ingredients are placed at night for simplicity and extra safety around sun exposure.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first and following it with your retinol. Because this product lacks harsh ingredients and contains soothing components like glycerin and sodium hyaluronate, it is unlikely to irritate your skin when paired with a retinoid.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/)

### How often should I use it?

You can use this treatment in the evening as part of your routine. Oily skin needs lighter serums and gel hydrators with niacinamide and salicylic acid to stay fresh and balanced.

### Can this serum clog pores, cause breakouts or purging for oily skin?

This serum is unlikely to cause breakouts or clog pores on oily skin, as it is free of harsh ingredients and contains soothing components like glycerin and sodium hyaluronate. Oily skin often benefits from lightweight hydrators and antioxidants such as aminopropyl ascorbyl phosphate and glycerin to support skin health without feeling heavy.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Is it fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for oily skin

- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/es/p/skinceuticals/c-e-ferulic/for/oily-skin) — High fit — €169.99 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/es/p/neogen-dermalogy/real-vita-c-serum/for/oily-skin) — High fit — €29.76 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/es/p/neogen-dermalogy/real-vitamin-c-serum/for/oily-skin) — High fit — €29.76 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/es/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — €20.50 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/es/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-skin) — Superior fit — €36.00 at Amazon
- Moisturizer: [SKIN1004 Centella Cream](https://lovi.care/skincare/es/p/skin1004/centella-cream/for/oily-skin) — Superior fit — €17.49 at Amazon

## Where to buy

No store in Spain has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, Caprylic Capric Triglyceride, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Squalane, Aminopropyl Ascorbyl Phosphate, Sodium Hyaluronate, Hydrolyzed Sodium Hyaluronate, Cutaneous Lysate, Tetrapeptide-21, Palmitoyl Tripeptide-1 Acetate, Butylene Glycol, Ethylhexylglycerin, Pullulan, Acetyl Glucosamine, Ethylene Acrylic Acid Copolymer, Polysorbate 60, Proline, Arginine, Glycine, Glutamine, Chlorphenesin, Nannochloropsis Oculata Extract, Capryloyl Carnosine, Poloxamer 338, Silica, Trifluoroacetyl Tripeptide-2, Dextran, Sorbitan Isostearate, Potassium Sorbate, Sodium Benzoate, Tocopherol, Disodium Edta, Sodium Hydroxide, Phenoxyethanol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/neocutis/bio-serum-firm/for/oily-skin
- United Kingdom: https://lovi.care/skincare/uk/p/neocutis/bio-serum-firm/for/oily-skin
- Ireland: https://lovi.care/skincare/ie/p/neocutis/bio-serum-firm/for/oily-skin
- Germany: https://lovi.care/skincare/de/p/neocutis/bio-serum-firm/for/oily-skin
- France: https://lovi.care/skincare/fr/p/neocutis/bio-serum-firm/for/oily-skin
- Italy: https://lovi.care/skincare/it/p/neocutis/bio-serum-firm/for/oily-skin
- Netherlands: https://lovi.care/skincare/nl/p/neocutis/bio-serum-firm/for/oily-skin
- Spain: https://lovi.care/skincare/es/p/neocutis/bio-serum-firm/for/oily-skin (this page)
- Canada: https://lovi.care/skincare/ca/p/neocutis/bio-serum-firm/for/oily-skin
- Australia: https://lovi.care/skincare/au/p/neocutis/bio-serum-firm/for/oily-skin
- Singapore: https://lovi.care/skincare/sg/p/neocutis/bio-serum-firm/for/oily-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/neocutis/bio-serum-firm/for/oily-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/neocutis/bio-serum-firm/for/oily-skin