# NATURIUM Retinaldehyde Cream Serum 0.05% for oily acne-prone skin

**Lovi Fit: Average fit for oily acne-prone skin.**
Oily Skin Fit: Average · Effectiveness: Average · Safety: Excellent.

Page: https://lovi.care/skincare/es/p/naturium/retinaldehyde-cream-serum-0-05/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Brand: [NATURIUM](https://lovi.care/skincare/es/brands/naturium)
Category: [Serums and treatments](https://lovi.care/skincare/es/best/serums)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for oily acne-prone skin; other serums fit it better.

## Why this fit

- Offers moderate suitability for your oily skin as retinaldehyde promotes cell turnover and provides antioxidant benefits, while glycerin offers hydration. However, the formula lacks sufficient ingredients specifically targeting oil regulation for your primary concerns of acne and oiliness.
- The yeast extract and apricot kernel oil contribute to soothing and general skincare benefits, but they do not directly address your main issues of blemishes and breakouts.
- The product is safe for your skin, with no risks of irritation due to the absence of harsh ingredients and the inclusion of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/es/p/naturium/retinaldehyde-cream-serum-0-05/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/es/p/naturium/retinaldehyde-cream-serum-0-05/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/es/p/naturium/retinaldehyde-cream-serum-0-05/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/es/p/naturium/retinaldehyde-cream-serum-0-05/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/es/p/naturium/retinaldehyde-cream-serum-0-05/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/es/p/naturium/retinaldehyde-cream-serum-0-05/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/es/p/naturium/retinaldehyde-cream-serum-0-05/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/es/p/naturium/retinaldehyde-cream-serum-0-05/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/es/p/naturium/retinaldehyde-cream-serum-0-05/for/oily-acne-prone-skin): Average (this page)

## Key ingredients

Retinaldehyde, Biofermented Oligopeptide, Retinal, Amino Acids, Punica Granatum Seed Extract

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical moisturizers improved skin barrier function and surface moisture, while a postbiotic moisturizer with yeast extract uniquely supported microbiome balance and modulated biomarkers of skin barrier, structure, and inflammation in participants and ex vivo explants exposed to environmental aggressors. ([Journal of Clinical Medicine, 2023](https://pubmed.ncbi.nlm.nih.gov/37763018/))
- Twice daily application of retinaldehyde 0.1% and 0.05% creams for 3 months improved skin texture and hydration and reduced transepidermal water loss in 40 female Korean volunteers, with only the 0.1% cream significantly improving the melanin index. ([Journal of Cosmetic Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29663701/))
- Topical retinaldehyde demonstrated significant antibacterial activity against gram-positive bacteria both in vitro and in vivo, leading to decreased bacterial counts without inducing resistance. ([Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12218231/))
- Topical 0.05% retinaldehyde applied over 1 year significantly increased epidermal thickness of the temple and cutaneous elasticity compared to an emollient control group in 40 aging skin patients. ([Dermatology, 1999](https://pubmed.ncbi.nlm.nih.gov/10473959/))
- Phenolic-rich pomegranate peel extract formulated into a serum and mask showed significantly better facial skin lightening efficacy than placebo in 30 volunteers over 28 days. ([Planta Medica, 2020](https://pubmed.ncbi.nlm.nih.gov/32428937/))
- Topical application of a 2% cream containing combined fruit extracts for 56 days significantly reduced wrinkle depth by 11.5%, length by 10.07%, and area by 29.55% in 21 female subjects compared to a placebo. ([Clinical, Cosmetic and Investigational Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/26203268/))
- A topical microemulsion containing Punica granatum extract significantly reduced skin erythema and melanin compared to a placebo in healthy Asian subjects over 12 weeks. ([Postepy Dermatologii I Alergologii, 2014](https://pubmed.ncbi.nlm.nih.gov/25610348/))

## Why other serums fit oily acne-prone skin better

- A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo. ([Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/))
- Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo. ([BioMed Research International, 2022](https://pubmed.ncbi.nlm.nih.gov/35342760/))

## What reviewers say

This serum is widely praised as an excellent, gentle introduction to retinaldehyde, with users reporting visible improvements in skin texture, brightness, and acne control without the harsh irritation often associated with retinoids.

- Liked: Gentle & Non-irritating (mostly mentioned)
- Liked: Improves Texture & Tone (often mentioned)
- Liked: Pleasant Texture (often mentioned)
- Liked: Effective for Acne (sometimes noted)
- Liked: Great Value (sometimes noted)
- Disliked: Slow results (sometimes noted)
- Disliked: Breakouts/Purging (rarely noted)
- Disliked: Dryness (rarely noted)
- Disliked: Skin irritation (rarely noted)

## How to apply

- Could be used as part of your PM routine. Start 3 times a week and build up to daily use if your skin tolerates it well.
- Apply your serum after cleansing and toning, but before putting on your moisturizer.
- Gently press 2 to 3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on clean, dry skin to help manage your blemishes safely.
- Do a patch test before your first use and avoid the delicate eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Naturium Retinaldehyde work for oily acne-prone skin?

Naturium Retinaldehyde Cream Serum 0.05% works moderately well for oily acne-prone skin, as it helps promote cell turnover while offering hydration and soothing benefits. It is safe and unlikely to cause irritation, though a product of this type needs ingredients like niacinamide, propolis, or Vitamin C to better manage excess oil and breakouts.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Journal of Clinical Medicine, 2023](https://pubmed.ncbi.nlm.nih.gov/37763018/)

### Which ingredients make this serum a good fit for oily acne-prone skin?

Retinaldehyde, retinal, and glycerin make this serum a fit by promoting cell turnover and providing hydration, though a product of this type needs ingredients like niacinamide, propolis, or Vitamin C to better target oil regulation, excess oil, and blemishes.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Retinal do for oily acne-prone skin?

Retinal helps clear clogged pores, reduces bumps and pimples, and helps balance oil production for oily, acne-prone skin. It is generally well tolerated when used regularly as part of an acne skincare routine.
Sources: [Clinical and Experimental Dermatology, 1999](https://pubmed.ncbi.nlm.nih.gov/10564319/), [European Review for Medical and Pharmacological Sciences, 2014](https://pubmed.ncbi.nlm.nih.gov/25219827/)

### What does Biofermented Oligopeptide do for oily acne-prone skin?

Biofermented oligopeptide helps balance oily skin by reducing excess oil production and managing breakouts while keeping the skin calm. It also helps smooth out fine lines with a lower chance of the irritation often linked to strong anti-aging treatments.
Sources: [Life, 2024](https://pubmed.ncbi.nlm.nih.gov/39459512/)

### Where does this serum go in a skincare routine for oily acne-prone skin?

This serum goes in the evening routine after cleansing and toning, and before moisturizing. Oily acne-prone skin needs a product of this type that also includes ingredients to control excess oil and clear breakouts.

### Can I use this serum with glycolic acid, and in what order?

Using this serum with glycolic acid may easily lead to dryness or irritation, so it is best to use them on alternate nights rather than together. When combining potent exfoliating acids and retinoids, applying them separately helps protect your skin barrier from becoming too sensitive.

### How often should I use this serum?

You can use this treatment in the evening as part of your routine. It offers moderate suitability for your oily skin, though an oily acne-prone skin type needs oil-regulating ingredients to better manage blemishes and breakouts.

### Can this serum clog pores, cause breakouts or purging for oily acne-prone skin?

This serum is unlikely to cause breakouts or purging for oily acne-prone skin, as it has a very low risk of causing blemishes and contains soothing components with a safe profile. However, because it offers only moderate suitability for your skin, an ideal product of this type also needs ingredients that actively control oil and directly target blemishes.
Sources: [Journal of Clinical Medicine, 2023](https://pubmed.ncbi.nlm.nih.gov/37763018/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for oily acne-prone skin

- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/es/p/neogen-dermalogy/real-vitamin-c-serum/for/oily-acne-prone-skin) — Superior fit — €29.76 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/es/p/neogen-dermalogy/real-vita-c-serum/for/oily-acne-prone-skin) — High fit — €29.76 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/es/p/skin1004/probio-cica-intensive-ampoule/for/oily-acne-prone-skin) — High fit — €21.99 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/es/p/cerave/foaming-facial-cleanser/for/oily-acne-prone-skin) — Superior fit — €20.50 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/es/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-acne-prone-skin) — Superior fit — €36.00 at Amazon
- SPF: [Dear, Klairs All-day Airy Sunscreen](https://lovi.care/skincare/es/p/dear-klairs/all-day-airy-sunscreen/for/oily-acne-prone-skin) — Superior fit — €21.00 at Amazon

## Where to buy

No store in Spain has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, Propanediol, Triheptanoin, C13-15 Alkane, Coco-Caprylate Caprate, Carbomer, Yeast Extract, Apricot Polyglyceryl-6 Esters Kernel Oil, Amino Acids, Punica Granatum Seed Extract, Cetyl Diglyceryl Tris Trimethylsiloxy Silylethyl Dimethicone, Hydrolyzed Yeast Extract, Olivine Extract, Dilinoleic Acid Butanediol Copolymer, Cellulose, Phenoxyethanol, Sorbitan Oleate, Sodium Metabisulfite, Retinal, Guanosine, Uracil, Polyacrylate Crosspolymer-6, C9-12 Alkane, Caprylyl Glycol, Polyglyceryl-10 Dipalmitate, Dipropylene Glycol, Sodium Hydroxide, Glyceryl Polyacrylate, Tocopherol, Pvm Ma Copolymer, Adenosine Phosphate, Castor Ipdi Copolymer Oil, Potassium Sorbate, Hexadecene, Sodium Benzoate, T-Butyl Alcohol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

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- United States: https://lovi.care/skincare/p/naturium/retinaldehyde-cream-serum-0-05/for/oily-acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/naturium/retinaldehyde-cream-serum-0-05/for/oily-acne-prone-skin
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