# NATURIUM Azelaic Topical Acid 10% for sensitive skin

**Lovi Fit: High fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: Excellent.

Page: https://lovi.care/skincare/es/p/naturium/azelaic-topical-acid-10/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Brand: [NATURIUM](https://lovi.care/skincare/es/brands/naturium)
Category: [Serums and treatments](https://lovi.care/skincare/es/best/serums)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for sensitive skin; a few serums fit it even better.

## Why this fit

- Highly suitable for normal skin, this formula leverages potassium azeloyl diglycinate and niacinamide to address redness and blemishes by calming inflammation and regulating sebum production.
- Glycerin and sodium hyaluronate provide essential hydration, supporting your skin's barrier function and soothing irritation.
- The product is safe for your sensitive skin, containing no harsh ingredients and including soothing components like niacinamide and glycerin.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/es/p/naturium/azelaic-topical-acid-10/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/es/p/naturium/azelaic-topical-acid-10/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/es/p/naturium/azelaic-topical-acid-10/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/es/p/naturium/azelaic-topical-acid-10/for/sensitive-skin): High (this page)
- [Acne-prone skin](https://lovi.care/skincare/es/p/naturium/azelaic-topical-acid-10/for/acne-prone-skin): Superior
- [Skin with dark spots](https://lovi.care/skincare/es/p/naturium/azelaic-topical-acid-10/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/es/p/naturium/azelaic-topical-acid-10/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/es/p/naturium/azelaic-topical-acid-10/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/es/p/naturium/azelaic-topical-acid-10/for/oily-acne-prone-skin): High

## Key ingredients

Azelaic Acid, Niacinamide, Ethyl Ascorbic Acid Ascorbic Acid, Potassium Azeloyl Diglycinate, Sodium Hyaluronate

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Hyaluronic acid extracts are safe and efficacious products for skin repair when used in tissue regeneration alone or in combination with herbal or Western medicine. ([Journal of Pharmacy & Pharmaceutical Sciences, 2015](https://pubmed.ncbi.nlm.nih.gov/25877441/))
- Azelaic acid nanocrystal hydrogel 10% achieved a higher success rate and greater lesion reduction than azelaic acid cream 20% in patients with mild to moderate facial acne. ([Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/))
- Application of 15% azelaic acid gel significantly reduced post-inflammatory erythema and hyperpigmentation, decreased hemoglobin and melanin content, improved quality of life, and contributed to acne improvement in patients with mild to moderate acne compared to placebo. ([Dermatology and Therapy, 2024](https://pubmed.ncbi.nlm.nih.gov/38734843/))
- Topical application of a dermocosmetic containing Myrtus communis extract and azelaic acid reduced acne relapses and helped maintain remission compared to a light moisturizing cream in adult females in the acne maintenance phase over 16 weeks. ([Journal of the European Academy of Dermatology and Venereology, 2023](https://pubmed.ncbi.nlm.nih.gov/36729399/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))

## What reviewers say

Most users report improved skin texture and a brighter complexion without experiencing irritation. A smaller number of users noted initial breakouts or found the scent to be unpleasant.

- Liked: Improves texture (mostly mentioned)
- Liked: Clears acne (often mentioned)
- Liked: Gentle and non-irritating (often mentioned)
- Liked: Reduces redness (often mentioned)
- Liked: Elegant texture (sometimes noted)
- Disliked: Unpleasant smell (sometimes noted)
- Disliked: Drying or sticky (rarely noted)
- Disliked: Initial breakouts (rarely noted)
- Disliked: Slow results (rarely noted)

## How to apply

- Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
- Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
- Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
- Always do a patch test before your first use and avoid getting the serum too close to your eyes .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Naturium Azelaic Topical Acid 10% a great fit for sensitive skin?

Naturium Azelaic Topical Acid 10% is a great fit because it uses potassium azeloyl diglycinate and niacinamide to calm redness and soothe irritation without harsh ingredients. Glycerin and sodium hyaluronate also provide essential hydration to support your skin's barrier function.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for sensitive skin?

This serum is a great fit for sensitive skin because it uses niacinamide, potassium azeloyl diglycinate, and glycerin to calm redness and soothe irritation. Sodium hyaluronate also helps provide essential hydration to support your skin barrier without harsh ingredients.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Azelaic Acid do for sensitive skin?

Azelaic acid helps calm sensitive, red, or easily irritated skin by soothing inflammation and reducing redness. It is generally well-tolerated and is unlikely to cause severe reactions, making it a gentle option for skin that flares up easily.
Sources: [Experimental Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/20545756/), [Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/21637903/)

### What does Niacinamide do for sensitive skin?

Niacinamide helps calm sensitive skin by strengthening the skin barrier and reducing redness and irritation. It is very well tolerated and may improve overall comfort and resilience with regular use.
Sources: [Cutis, 2005](https://pubmed.ncbi.nlm.nih.gov/16209160/), [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/)

### Where does this serum go in a skincare routine for sensitive skin?

This treatment goes in the evening routine after your toner and before your moisturizer. Putting it in the evening keeps it simple and provides extra safety around sun exposure.

### Can I use it with retinol, and in what order?

You can use this treatment with retinol by applying the retinol first at night and following it with this product, or by using them on alternating nights to keep your skin calm. This formula is unlikely to irritate sensitive skin because it contains soothing ingredients like niacinamide and glycerin to support your skin barrier.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/)

### How often should I use this serum?

You can use this treatment in your evening routine once a week to start. Because it is a great fit for your sensitive skin, you may carefully use it more often if your skin tolerates it well.

### Can it clog pores, cause breakouts or purging for sensitive skin?

This product is unlikely to clog pores or cause major breakouts on sensitive skin, as initial breakouts are reported as a low risk. Its soothing ingredients help calm irritation while supporting your skin's barrier function.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for sensitive skin

- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/es/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/sensitive-skin) — Superior fit — €57.00 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/es/p/skinceuticals/c-e-ferulic/for/sensitive-skin) — High fit — €169.99 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/es/p/neogen-dermalogy/real-vitamin-c-serum/for/sensitive-skin) — High fit — €29.76 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/es/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — €39.80 at Amazon
- Soothing Toner: [SKIN1004 Centella Asiatica Toning Toner](https://lovi.care/skincare/es/p/skin1004/centella-asiatica-toning-toner/for/sensitive-skin) — Superior fit — €23.99 at Amazon
- Moisturizer with Sun Protection: [Bioderma Bioderma Photoderm Mineral SPF 50+](https://lovi.care/skincare/es/p/bioderma/photoderm-mineral-fluide-spf50/for/sensitive-skin) — Superior fit — €19.13 at Amazon

## Where to buy

No store in Spain has a checked price for this product, so the page shows none.

## Ingredients

Water, Propanediol, Potassium Azeloyl Diglycinate, Polyacrylate Crosspolymer-6, Niacinamide, Ethyl Ascorbic Acid, Caprylyl Glycol, Coffea Arabica Seed Extract Coffee Seed Extract, Sodium Hyaluronate, Phenylpropanol, Phenoxyethanol, Citric Acid, Potassium Chloride, Glycerin, Chlorphenesin, Tocopherol, Potassium Sorbate, Sodium Benzoate
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/naturium/azelaic-topical-acid-10/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/naturium/azelaic-topical-acid-10/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/naturium/azelaic-topical-acid-10/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/naturium/azelaic-topical-acid-10/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/naturium/azelaic-topical-acid-10/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/naturium/azelaic-topical-acid-10/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/naturium/azelaic-topical-acid-10/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/naturium/azelaic-topical-acid-10/for/sensitive-skin (this page)
- Canada: https://lovi.care/skincare/ca/p/naturium/azelaic-topical-acid-10/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/naturium/azelaic-topical-acid-10/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/naturium/azelaic-topical-acid-10/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/naturium/azelaic-topical-acid-10/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/naturium/azelaic-topical-acid-10/for/sensitive-skin