# Murad Retinal ReSculpt Overnight Treatment for dry skin

**Lovi Fit: Average fit for dry skin.**
Dry Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/es/p/murad/retinal-resculpt-overnight-treatment/for/dry-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Brand: [Murad](https://lovi.care/skincare/es/brands/murad)
Category: [Serums and treatments](https://lovi.care/skincare/es/best/serums)

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for dry skin; other serums fit it better.

## Why this fit

- Offers moderate suitability for your dry skin due to the humectant action of urea and trehalose, but it lacks sufficient emollient ingredients like shea butter in higher concentrations to fully address dryness.
- The presence of retinal provides excellent wrinkle reduction by minimizing fine lines and wrinkles, though it may offer moderate exfoliation that is not ideal for your dry or flaky skin.
- The product is safe for your dry skin, as it contains no harsh ingredients and includes soothing components like shea butter and oat kernel extract.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/es/p/murad/retinal-resculpt-overnight-treatment/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/es/p/murad/retinal-resculpt-overnight-treatment/for/dry-skin): Average (this page)
- [Combination skin](https://lovi.care/skincare/es/p/murad/retinal-resculpt-overnight-treatment/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/es/p/murad/retinal-resculpt-overnight-treatment/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/es/p/murad/retinal-resculpt-overnight-treatment/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/es/p/murad/retinal-resculpt-overnight-treatment/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/es/p/murad/retinal-resculpt-overnight-treatment/for/mature-skin): Superior
- [Dry sensitive skin](https://lovi.care/skincare/es/p/murad/retinal-resculpt-overnight-treatment/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/es/p/murad/retinal-resculpt-overnight-treatment/for/oily-acne-prone-skin): Average

## Key ingredients

Retinal, Squalane, Butyrospermum Parkii Butter Shea Butter, Avena Sativa Kernel Extract Oat Kernel Extract, Urea

## What the research says

- Sodium trehalose sulfate decreased transepidermal water loss and increased stratum corneum water content in participants with low stratum corneum water content when applied for 4 weeks compared to placebo. ([Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38606717/))
- Colloidal oat extracts diminished pro-inflammatory cytokines in vitro and colloidal oat lotion improved skin dryness, scaling, roughness, and itch intensity in healthy female subjects compared to baseline. ([Journal of Drugs in Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25607907/))
- Colloidal oatmeal induced skin barrier-related gene expression in vitro and showed significant clinical improvements in skin dryness, moisturization, and barrier in 50 healthy female subjects treated with a colloidal oatmeal lotion. ([Journal of Drugs in Dermatology, 2016](https://pubmed.ncbi.nlm.nih.gov/27272074/))
- A multiple W/O/W emulsion containing Rosmarinus officinalis L., Avena sativa L., and Linum usitatissimum L. extracts showed no irritant, phototoxic, inflammatory, or allergenic potential in human skin models and patch tests, establishing its safety as a cosmetic base. ([Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/34065623/))
- Twice daily application of retinaldehyde 0.1% and 0.05% creams for 3 months improved skin texture and hydration and reduced transepidermal water loss in 40 female Korean volunteers, with only the 0.1% cream significantly improving the melanin index. ([Journal of Cosmetic Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29663701/))
- Topical retinaldehyde demonstrated significant antibacterial activity against gram-positive bacteria both in vitro and in vivo, leading to decreased bacterial counts without inducing resistance. ([Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12218231/))
- Topical 0.05% retinaldehyde applied over 1 year significantly increased epidermal thickness of the temple and cutaneous elasticity compared to an emollient control group in 40 aging skin patients. ([Dermatology, 1999](https://pubmed.ncbi.nlm.nih.gov/10473959/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))
- A combination cream of stimu-tex AS and saccharide isomerate reduced erythema, increased skin capacitance, and reduced transepidermal water loss compared to placebo in 20 subjects after fractional CO2 laser procedure without causing serious adverse events. ([Lasers in Medical Science, 2025](https://pubmed.ncbi.nlm.nih.gov/41134387/))
- A skin barrier restoring cream with shea butter, silkflo, and vitamin E increased type I procollagen synthesis, enhanced antioxidant enzyme activity, decreased reactive oxygen species generation, and promoted hyaluronic acid production in H2O2-stimulated human keratinocyte cells compared to untreated cells. ([International Journal of Cosmetic Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39528438/))
- A repair cream containing Rhealba oat plantlets extract, l-ALA-l-GLU dipeptide, and hyaluronic acid provided immediate relief and was judged by doctors as good or very good in 96.8% of cases for wound healing in 2,363 patients following dermatological acts. ([Clinical, Cosmetic and Investigational Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/30519069/))
- Topically applied Avena sativa and Avena Rhealba oatmeal extracts significantly reduced skin irritation parameters including a* parameter increase and blood flow increase compared to vehicle in 12 healthy individuals subjected to the sodium lauryl sulfate irritation model. ([Skin Pharmacology and Applied Skin Physiology, 2002](https://pubmed.ncbi.nlm.nih.gov/11867969/))
- Colloidal oat increased the growth rate, metabolism, and lactic acid production of Staphylococcus epidermidis compared to Staphylococcus aureus in vitro, matching clinical increases in lactic acid on dry skin after 6 weeks of lotion use. ([Clinical, Cosmetic and Investigational Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33500646/))
- Topical 40% urea cream achieved improvement in less time and showed superiority over 12% ammonium lactate lotion in skin roughness, fissure reduction, thickness, and dryness at day 14 in patients treated for moderate to severe xerosis. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/11978141/))
- Topical treatment with K101 achieved a significantly higher mycological cure rate compared to placebo in patients with ≤50% nail involvement (27.2% vs 10.4%), while showing early visible improvements in nail appearance and no safety issues. ([Mycoses, 2012](https://pubmed.ncbi.nlm.nih.gov/22681227/))

## Why other serums fit dry skin better

- A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/))
- Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days. ([Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/))

## What reviewers say

Users report this treatment effectively targets advanced signs of aging, leading to visibly firmer, smoother, and bouncier skin. It is frequently praised for delivering results on deep wrinkles and sagging without the typical irritation associated with potent retinoids.

- Liked: Visibly smooths texture (mostly mentioned)
- Liked: Firms and lifts (often mentioned)
- Liked: Gentle and non-irritating (often mentioned)
- Disliked: High price point (often mentioned)
- Liked: Fast-acting results (sometimes noted)
- Liked: Pleasant consistency (sometimes noted)
- Disliked: Deceiving packaging (sometimes noted)
- Disliked: Lack of results (rarely noted)
- Disliked: Scent/Fragrance (rarely noted)

## How to apply

- Apply this serum PM, starting 3×/week and working up to daily use as your skin adjusts.
- Place the serum after cleansing and toner, but right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on slightly damp skin to help lock in extra moisture.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Murad Retinal ReSculpt Overnight Treatment work for dry skin?

This treatment works okay for dry skin, offering some moisture with urea and trehalose, but it lacks enough rich, softening ingredients like shea butter to fully handle dryness. A treatment for dry skin needs more heavy-duty moisturizers, soothing barrier ingredients, and skin-repairing components like ceramides, peptides, and niacinamide.
Sources: [Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38606717/)

### Which ingredients make this treatment a good fit for dry skin?

This treatment works for dry skin thanks to urea and trehalose, which help hold on to moisture, along with soothing oat kernel extract and shea butter. A product of this type needs richer moisturizing ingredients and barrier-supporting additions like ceramides, niacinamide, or peptides to fully care for dry skin.
Sources: [Journal of Drugs in Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25607907/), [Journal of Drugs in Dermatology, 2016](https://pubmed.ncbi.nlm.nih.gov/27272074/)

### What does Retinal do for dry skin?

Retinal helps smooth dry skin and is unlikely to cause severe dryness when used properly, though it may occasionally lead to mild scaling or irritation as the skin adjusts. This ingredient works best when paired with gentle moisturizers to keep the face feeling soft and comfortable.
Sources: [Dermatology, 1999](https://pubmed.ncbi.nlm.nih.gov/10473959/), [Clinical Interventions in Aging, 2006](https://pubmed.ncbi.nlm.nih.gov/18046911/)

### What does Squalane do for dry skin?

Squalane helps keep dry skin soft and smooth by acting as a hydrating agent that locks in moisture and prevents water loss. It is unlikely to cause irritation and may protect the skin from damage while improving overall hydration.
Sources: [Advances in Food and Nutrition Research, 2012](https://pubmed.ncbi.nlm.nih.gov/22361190/), [Molecules, 2009](https://pubmed.ncbi.nlm.nih.gov/19169201/)

### Where does this treatment go in a skincare routine for dry skin?

This treatment goes in the evening routine after cleansing and before moisturizing. A product of this type works best for dry skin when it also includes rich softening and smoothing ingredients in higher amounts to fully comfort dryness.

### Can I use this treatment with niacinamide, and in what order?

You can use this treatment with niacinamide by applying niacinamide first and following with this treatment once it absorbs. This approach helps keep your skin calm, though dry skin of this type needs more rich, softening ingredients and gentle hydration to fully address dryness.
Sources: [Journal of Drugs in Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25607907/), [Journal of Drugs in Dermatology, 2016](https://pubmed.ncbi.nlm.nih.gov/27272074/)

### How often should I use this treatment?

You can use this treatment in your evening routine, starting just once a week to see how your skin reacts since it may cause flaking on dry skin. To properly care for dry skin, this type of product needs extra rich softening ingredients and heavy moisturizing butters to fully lock in hydration and prevent dryness.
Sources: [Journal of Drugs in Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25607907/), [Journal of Drugs in Dermatology, 2016](https://pubmed.ncbi.nlm.nih.gov/27272074/)

### Can this treatment clog pores, cause breakouts or purging for dry skin?

This treatment is unlikely to clog pores or cause breakouts on dry skin, but the retinal it contains may cause mild flaking or purging as your skin adjusts. A product of this type needs richer softening ingredients and soothing extracts to fully comfort dry skin.

### Is this treatment fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (citronellol and parfum). Cetearyl alcohol and cetyl alcohol are fatty alcohols, which soften the skin.

## Alternatives for dry skin

- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/es/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/dry-skin) — Superior fit — €57.00 at Amazon
- [ma:nyo Bifida Biome Complex Ampoule](https://lovi.care/skincare/es/p/ma-nyo/bifida-biome-complex-ampoule/for/dry-skin) — Superior fit — €18.50 at Amazon
- [Augustinus Bader The Serum](https://lovi.care/skincare/es/p/augustinus-bader/the-serum/for/dry-skin) — Superior fit — €333.00 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/es/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — €8.85 at Amazon
- Hydrating Toner: [Paula's Choice Resist Advanced Replenishing Toner](https://lovi.care/skincare/es/p/paula-s-choice/advanced-replenishing-toner/for/dry-skin) — Superior fit — €34.00 at Amazon
- Moisturizer: [d'Alba First Spray Serum](https://lovi.care/skincare/es/p/d-alba/first-spray-serum/for/dry-skin) — Superior fit — €16.99 at Amazon

## Where to buy

No store in Spain has a checked price for this product, so the page shows none.

## Ingredients

Water, Diisostearyl Malate, Pentylene Glycol, Polyglyceryl-3 Methylglucose Distearate, Zea Mays Kernel Extract, Squalane, Propanediol, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Glycerin, Cetearyl Alcohol, Glyceryl Ricinoleate, Avena Sativa Kernel Extract Oat Kernel Extract, Butyrospermum Parkii Butter Shea Butter, Retinal, Urea, Yeast Amino Acids, Trehalose, Inositol, Taurine, Betaine, Anigozanthos Flavidus Extract, Phosphatidylcholine, Olea Europaea Leaf Extract Olive Leaf Extract, Mannitol, Ethylhexylglycerin, Dimethyl Isosorbide, Glyceryl Stearate, Sodium Stearoyl Glutamate, Cetyl Alcohol, Hectorite, Xanthan Gum, Sodium Chloride, Polysorbate 60, Sorbitan Isostearate, Leuconostoc Radish Root Ferment Filtrate, Tetrasodium Glutamate Diacetate, Citric Acid, Sodium Benzoate, Chlorphenesin, Potassium Sorbate, Citronellol, Alpha-Isomethyl Ionone, Parfum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/murad/retinal-resculpt-overnight-treatment/for/dry-skin
- United Kingdom: https://lovi.care/skincare/uk/p/murad/retinal-resculpt-overnight-treatment/for/dry-skin
- Ireland: https://lovi.care/skincare/ie/p/murad/retinal-resculpt-overnight-treatment/for/dry-skin
- Germany: https://lovi.care/skincare/de/p/murad/retinal-resculpt-overnight-treatment/for/dry-skin
- France: https://lovi.care/skincare/fr/p/murad/retinal-resculpt-overnight-treatment/for/dry-skin
- Italy: https://lovi.care/skincare/it/p/murad/retinal-resculpt-overnight-treatment/for/dry-skin
- Netherlands: https://lovi.care/skincare/nl/p/murad/retinal-resculpt-overnight-treatment/for/dry-skin
- Spain: https://lovi.care/skincare/es/p/murad/retinal-resculpt-overnight-treatment/for/dry-skin (this page)
- Canada: https://lovi.care/skincare/ca/p/murad/retinal-resculpt-overnight-treatment/for/dry-skin
- Australia: https://lovi.care/skincare/au/p/murad/retinal-resculpt-overnight-treatment/for/dry-skin
- Singapore: https://lovi.care/skincare/sg/p/murad/retinal-resculpt-overnight-treatment/for/dry-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/murad/retinal-resculpt-overnight-treatment/for/dry-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/murad/retinal-resculpt-overnight-treatment/for/dry-skin