# MISSHA Time Revolution Night Repair Ampoule Cream 5X for sensitive skin

**Lovi Fit: Average fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/es/p/missha/time-revolution-night-repair-ampoule-cream-5x/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Brand: [MISSHA](https://lovi.care/skincare/es/brands/missha)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/es/best/moisturizers)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for sensitive skin; other moisturizers fit it better.

## Why this fit

- Offers moderate hydration and soothing benefits for your normal, sensitive skin, as niacinamide and glycerin work to improve barrier function and retain moisture, which can help with redness and irritation.
- The inclusion of Centella Asiatica Extract and Anthemis Nobilis Oil further supports calming effects, making it generally well-tolerated.
- The product is safe for your sensitive skin, containing no harsh ingredients and featuring soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/es/p/missha/time-revolution-night-repair-ampoule-cream-5x/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/es/p/missha/time-revolution-night-repair-ampoule-cream-5x/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/es/p/missha/time-revolution-night-repair-ampoule-cream-5x/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/es/p/missha/time-revolution-night-repair-ampoule-cream-5x/for/sensitive-skin): Average (this page)
- [Acne-prone skin](https://lovi.care/skincare/es/p/missha/time-revolution-night-repair-ampoule-cream-5x/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/es/p/missha/time-revolution-night-repair-ampoule-cream-5x/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/es/p/missha/time-revolution-night-repair-ampoule-cream-5x/for/mature-skin): Low
- [Dry sensitive skin](https://lovi.care/skincare/es/p/missha/time-revolution-night-repair-ampoule-cream-5x/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/es/p/missha/time-revolution-night-repair-ampoule-cream-5x/for/oily-acne-prone-skin): Average

## Key ingredients

Extreme Biome, Bifida Lysate Ferment, Niacinamide, Centella Asiatica Extract, Ceramide Np

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- Emulsions containing ceramides 1 and 3 improved skin hydration and reduced transepidermal water loss in sodium lauryl sulfate-irritated skin of fifteen healthy Asian women compared to a control emulsion. ([International Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18717861/))
- Topical application of Bifida Ferment Lysate strengthens the skin barrier function by upregulating barrier and antimicrobial peptide genes, exhibiting strong antioxidant properties, and decreasing inflammatory cytokine secretion in vitro. ([Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37218728/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))

## What reviewers say

This anti-aging night cream is highly effective for dry and mature skin, providing deep hydration and plumping for a softer, glowing, and more elastic complexion. While many users appreciate its rich, nourishing texture and good value, some with oily or acne-prone skin find it too heavy and occasionally experience breakouts or a greasy finish.

- Liked: Deeply moisturizing (mostly mentioned)
- Liked: Improves texture (often mentioned)
- Liked: Good value (sometimes noted)
- Liked: Rich consistency (sometimes noted)
- Disliked: Heavy or greasy (sometimes noted)
- Disliked: Fragrance sensitivity (rarely noted)
- Disliked: Packaging concerns (rarely noted)
- Disliked: Potential breakouts (rarely noted)

## How to apply

- Use this soothing AM and PM routine every day to keep your normal skin calm. Always remember to apply SPF in the morning after your moisturizer.
- Apply your moisturizer after your toner in the morning, and after your serum in the evening. This step locks in hydration and protects your skin.
- Gently press a small amount of the moisturizer evenly across your face. Avoid rubbing to keep your sensitive skin happy and calm.
- You can apply this gentle formula on dry or slightly damp skin for the best comfort. It works wonderfully on clean skin to soothe redness and irritation.
- Do a patch test before your very first use to check your skin's reaction. Avoid getting the product directly into your eyes .
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Missha Night Repair Ampoule Cream 5X work for sensitive skin?

This cream works decently for sensitive skin, offering moderate moisture and calming benefits that help keep redness and irritation under control. A moisturizing treatment for this skin type needs high concentrations of soothing ingredients like fermented centella asiatica and ceramides to repair the barrier and hydrate without overwhelming the skin.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [International Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18717861/)

### Which ingredients make this cream a good fit for sensitive skin?

This cream works for sensitive skin because glycerin, niacinamide, Centella Asiatica Extract, and Ceramide NP help lock in moisture, calm redness, and support a healthy skin barrier. To fit sensitive skin even better, a moisturizing treatment needs a high concentration of soothing fermented extracts and nourishing oils that calm irritation while keeping moisture balanced.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [International Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18717861/)

### What does Extreme Biome do for sensitive skin?

Extreme Biome helps keep sensitive skin calm and supports surface moisture when exposed to environmental stressors. Using a moisturizer with yeast extract and postbiotics may also balance the skin microbiome and protect the skin barrier.
Sources: [Journal of Clinical Medicine, 2023](https://pubmed.ncbi.nlm.nih.gov/37763018/)

### What does Bifida Ferment Lysate do for sensitive skin?

Bifida Ferment Lysate helps calm reactive skin, making it less sensitive and more resistant to daily irritation and physical or chemical aggression. It achieves this by strengthening your skin barrier and keeping moisture locked in while decreasing redness.
Sources: [Experimental Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/19624730/), [Scientific Reports, 2023](https://pubmed.ncbi.nlm.nih.gov/37803101/)

### Where does this cream go in a skincare routine for sensitive skin?

This cream works best as a treatment step in the evening routine, placed after your toner and before your moisturizer. Using it at night keeps things simple and provides extra safety around sun exposure.

### Can I use this cream with retinol, and in what order?

You can use this cream alongside retinol by applying it after your retinol treatment to help soothe the skin and reduce dryness. Using a barrier-supporting moisturizer helps maintain comfort and minimizes irritation when using strong active ingredients.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use this cream?

This cream works for your sensitive skin as an evening treatment, though other products fit it better. To care well for sensitive skin, look for products that provide gentle hydration, barrier-strengthening ingredients like ceramides, and calming extracts like centella asiatica without harsh irritants.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this cream clog pores, cause breakouts or purging for sensitive skin?

This cream is unlikely to clog pores or cause breakouts for sensitive skin, though it carries a low potential for breakouts among reviewers. To support breakout-prone sensitive skin, a product of this type needs non-greasy, soothing ingredients that calm irritation without heavy oils.

### Can I use this cream around the eyes or on my body?

This moisturizing treatment is generally well-tolerated on sensitive skin, though sensitive skin around the eyes and body needs products with extra soothing ingredients and richer moisture to prevent irritation.

### Is this cream fragrance-free and alcohol-free?

It has no fragrance and contains drying alcohol (alcohol).

## Alternatives for sensitive skin

- [belif The True Cream Aqua Bomb](https://lovi.care/skincare/es/p/belif/the-true-cream-aqua-bomb/for/sensitive-skin) — High fit — €35.00 at Amazon
- [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/es/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/sensitive-skin) — High fit — €13.67 at Amazon
- [The Ordinary Natural Moisturizing Factors + HA](https://lovi.care/skincare/es/p/the-ordinary/natural-moisturizing-factors-ha/for/sensitive-skin) — High fit — €11.50 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/es/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — €39.80 at Amazon
- Soothing Toner: [SKIN1004 Centella Asiatica Toning Toner](https://lovi.care/skincare/es/p/skin1004/centella-asiatica-toning-toner/for/sensitive-skin) — Superior fit — €23.99 at Amazon
- Moisturizer with Sun Protection: [Bioderma Bioderma Photoderm Mineral SPF 50+](https://lovi.care/skincare/es/p/bioderma/photoderm-mineral-fluide-spf50/for/sensitive-skin) — Superior fit — €19.13 at Amazon

## Where to buy

- Amazon.de: €31.99 (https://www.amazon.de/dp/B09648Y2RX?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- Notino: €53.90 (https://www.notino.es/missha/time-revolution-night-repair-ampoule-5x-tratamiento-intensivo-de-noche-con-efecto-antiarrugas/p-16145762/)
Prices checked 10 Oct – 4 Nov 2026.

## Ingredients

Water, Glycerin, Methyl Propanediol, Cyclohexasiloxane, Hydrogenated Polyisobutene, Caprylic Capric Triglyceride, Triethylhexanoin, Cetearyl Alcohol, Niacinamide, Dimethicone, 1,2-Hexanediol, Trehalose, Stearyl Alcohol, Beeswax, Cetyl Alcohol, Phytosteryl Isostearyl Cetyl Stearyl Behenyl Dimer Dilinoleate, Cetearyl Glucoside, Vinyl Dimethicone, Polyglyceryl-2 Stearate, Glyceryl Stearate, Palmitic Acid, Stearic Acid, Bergamot Oil Fruit, Hydroxyacetophenone, Dioscorea Japonica Root Extract, Ammonium Acryloyldimethyltaurate Vp Copolymer, Ethylhexylglycerin, Glycosyl Trehalose, Butylene Glycol, Alcohol, Bifida Lysate Ferment, Hydrogenated Hydrolysate Starch, Xanthan Gum, Adenosine, Raffinose, Glyceryl Polymethacrylate, Dextrin, Theobroma Cacao Shell Powder, Pelargonium Graveolens Oil Flower, Lecithin, Disodium Edta, Hydrogenated Lecithin, Camellia Sinensis Seed Oil, Argania Spinosa Kernel Oil, Olea Europaea Oil Fruit Olive Oil Fruit, Helianthus Annuus Seed Oil Sunflower Seed Oil, Jojoba Seed Oil, Camellia Japonica Seed Oil, Macadamia Ternifolia Seed Oil, Glucose, Centella Asiatica Extract, Ficus Carica Fruit Extract, Polyquaternium-51, Cetearyl Olivate, Ceramide Np, Lavandula Angustifolia Oil Lavender Oil, Citrus Aurantium Dulcis Peel Oil, Sorbitan Olivate, Phellodendron Amurense Bark Extract, Lactobacillus Ferment, Myristic Acid, Lactobacillus Acerola Cherry Ferment, Lactococcus Ferment, Leuconostoc Radish Root Ferment Filtrate, Bifida Ferment Filtrate, Lactobacillus Soybean Extract Ferment, Lactobacillus Punica Granatum Extract Fruit Ferment, Lactobacillus Lysate Ferment, Lactococcus Lysate Ferment, Monascus Extract, Sucrose Distearate, Rice Extract, Dipropylene Glycol, Biosaccharide Gum-1, Saccharomyces Ferment, Beta Vulgaris Root Extract, Daucus Carota Sativa Root Extract Carrot Root Extract, Brassica Oleracea Capitata Leaf Extract, Blueberry Fruit Extract, Solanum Melongena Fruit Extract, Anthemis Nobilis Oil Flower, Tocopherol, Sandalwood Oil, Bacillus Ferment
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/missha/time-revolution-night-repair-ampoule-cream-5x/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/missha/time-revolution-night-repair-ampoule-cream-5x/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/missha/time-revolution-night-repair-ampoule-cream-5x/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/missha/time-revolution-night-repair-ampoule-cream-5x/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/missha/time-revolution-night-repair-ampoule-cream-5x/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/missha/time-revolution-night-repair-ampoule-cream-5x/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/missha/time-revolution-night-repair-ampoule-cream-5x/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/missha/time-revolution-night-repair-ampoule-cream-5x/for/sensitive-skin (this page)
- Canada: https://lovi.care/skincare/ca/p/missha/time-revolution-night-repair-ampoule-cream-5x/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/missha/time-revolution-night-repair-ampoule-cream-5x/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/missha/time-revolution-night-repair-ampoule-cream-5x/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/missha/time-revolution-night-repair-ampoule-cream-5x/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/missha/time-revolution-night-repair-ampoule-cream-5x/for/sensitive-skin