# MEDIHEAL Madecassoside Blemish Pad for mature skin

**Lovi Fit: High fit for mature skin.**
Normal Skin Fit: Average · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/es/p/mediheal/madecassoside-blemish-pad/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Brand: [MEDIHEAL](https://lovi.care/skincare/es/brands/mediheal)
Category: [Toners](https://lovi.care/skincare/es/best/toners)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for mature skin; a few toners fit it even better.

## Why this fit

- Offers moderate benefits for wrinkles and fine lines as niacinamide and madecassoside support skin barrier function and collagen production, which is suitable for your normal skin.
- The presence of centella asiatica extract and madecassoside provides excellent soothing and calming effects, reducing redness and irritation.
- The product is safe for your normal skin due to the absence of prohibited or harsh ingredients, posing no risk of irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/es/p/mediheal/madecassoside-blemish-pad/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/es/p/mediheal/madecassoside-blemish-pad/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/es/p/mediheal/madecassoside-blemish-pad/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/es/p/mediheal/madecassoside-blemish-pad/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/es/p/mediheal/madecassoside-blemish-pad/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/es/p/mediheal/madecassoside-blemish-pad/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/es/p/mediheal/madecassoside-blemish-pad/for/mature-skin): High (this page)
- [Dry sensitive skin](https://lovi.care/skincare/es/p/mediheal/madecassoside-blemish-pad/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/es/p/mediheal/madecassoside-blemish-pad/for/oily-acne-prone-skin): Average

## Key ingredients

Madecassoside, Niacinamide, Centella Asiatica Extract, Allantoin, Dipotassium Glycyrrhizate

## What the research says

- Treatment with a combination of niacinamide and hyaluronic acid improved skin aging signs and demonstrated a senomorphic effect by decreasing SASP and autocrine signaling genes in women. ([Scientific Reports, 2024](https://pubmed.ncbi.nlm.nih.gov/39009698/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical 2% niacinamide significantly decreased sebum excretion rate in Japanese individuals and casual sebum levels in Caucasian individuals compared to placebo or baseline. ([Journal of Cosmetic and Laser Therapy, 2006](https://pubmed.ncbi.nlm.nih.gov/16766489/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment. ([Aesthetic Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29948103/))
- Combining 755 nm alexandrite laser with topical licorice gel significantly reduces terminal hair counts compared to alexandrite laser with placebo in women with idiopathic hirsutism. ([Evidence-based Complementary and Alternative Medicine, 2015](https://pubmed.ncbi.nlm.nih.gov/26273313/))
- Licochalcone A activated Nrf2 signaling, elevated cytoprotective enzymes, increased the reduced-to-oxidized glutathione ratio, and decreased reactive oxygen species in human fibroblasts and neutrophils, while a LicA-rich licorice extract lowered UVA-induced oxidative processes in vivo. ([Experimental Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25381913/))
- Bioactive glycyrrhizic acid and oxymatrine ionic liquid self-assembled nanomicelles significantly promoted the transdermal permeation, subcutaneous retention, and anti-photoaging efficacy of palmitoyl pentapeptide-4 in cellular and animal models compared to unformulated peptide. ([Advanced Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39783908/))

## What reviewers say

Based on a very large amount of data, this product is widely praised by users with acne-prone and sensitive skin for its ability to rapidly calm redness and smooth rough texture. Many users enjoy using the pads as a daily toner or mini-mask to fade post-acne marks and hydrate the skin, though a minority experience stickiness or initial purging.

- Liked: Calms redness (mostly mentioned)
- Liked: Generous essence (often mentioned)
- Liked: Improves texture (often mentioned)
- Liked: Convenient masking (sometimes noted)
- Disliked: Sticky/tacky finish (sometimes noted)
- Disliked: Causes breakouts (rarely noted)
- Disliked: Herbal scent (rarely noted)
- Disliked: Rough pad texture (rarely noted)

## How to apply

- Could be used as part of your AM or PM routine. Start using it 3 times a week and move to daily use if your skin tolerates it well.
- Apply this soothing toner right after cleansing and before your moisturizer or SPF .
- Gently press 2-3 drops of the soothing toner into your skin and let it absorb for a minute.
- Apply the soothing toner on slightly damp skin to help with better absorption.
- Avoid the sensitive eye area and do a patch test before your very first use .
- Video: https://storage.pora.ai/25abe7eb181ba53153fd15de2058c2a9.mp4

## Questions and answers

### What makes MEDIHEAL Madecassoside Blemish Pad a great fit for mature skin?

This soothing toner is a great fit because niacinamide and madecassoside help support collagen production and skin barrier function to offer moderate benefits for fine lines. It also calms irritation and reduces redness with centella asiatica extract and madecassoside, while being safe for everyday use.
Sources: [Scientific Reports, 2024](https://pubmed.ncbi.nlm.nih.gov/39009698/), [Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/)

### Which ingredients make this toner a good fit for mature skin?

Niacinamide and madecassoside make this toner a good fit for mature skin by supporting collagen production and skin barrier function to help smooth fine lines. Centella asiatica extract further helps calm the skin and reduce redness.
Sources: [Scientific Reports, 2024](https://pubmed.ncbi.nlm.nih.gov/39009698/), [Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/)

### What does Madecassoside do for mature skin?

Madecassoside helps mature skin by supporting collagen production to keep skin firm and smooth while calming irritation. It is unlikely to cause irritation and may protect against signs of aging and sun damage.
Sources: [Journal of Medicinal Food, 2023](https://pubmed.ncbi.nlm.nih.gov/37976111/), [Annales Pharmaceutiques Francaises, 1995](https://pubmed.ncbi.nlm.nih.gov/7741425/)

### What does Niacinamide do for mature skin?

Niacinamide helps mature skin by smoothing out fine lines and wrinkles, reducing dark spots, and improving overall skin elasticity. It is also very well tolerated and supports a strong skin barrier to keep skin looking healthy.
Sources: [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/), [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/)

### Where does this toner go in a skincare routine for mature skin?

This soothing toner goes in the morning routine right after cleansing and before moisturizing, and it is safe and gentle for mature skin. Niacinamide and madecassoside help support collagen production and calm redness while posing a low risk of irritation.
Sources: [Scientific Reports, 2024](https://pubmed.ncbi.nlm.nih.gov/39009698/), [Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/)

### Can I use this toner with retinol, and in what order?

You can use this toner alongside retinol by applying it right after cleansing to calm and hydrate your skin before using your retinol treatment. This approach helps support your skin barrier and is unlikely to cause irritation.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use this toner?

This toner is a great fit for your mature skin and can be used as part of your daily routine. Since it acts as an exfoliating pad, you should start using it just once a week to see how your skin reacts. If your skin tolerates it well and you see good results, you may carefully use it more often.

### Can this toner clog pores, cause breakouts or purging for mature skin?

This toner is unlikely to clog pores or cause breakouts for mature skin, as it lacks harsh ingredients and carries a low risk of irritation. Reviewers rarely report breakouts from using it.

### Is this toner fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for mature skin

- [Simple Kind to Skin Soothing Facial Toner](https://lovi.care/skincare/es/p/simple/kind-to-skin-soothing-facial-toner/for/mature-skin) — Superior fit — €9.93 at Amazon
- [1004 Skin Madagascar Centella Toning Toner](https://lovi.care/skincare/es/p/1004-skin/madagascar-centella-toning-toner/for/mature-skin) — Superior fit — €19.89 at Amazon
- [ROUND LAB Mugwort Calming Toner](https://lovi.care/skincare/es/p/round-lab/mugwort-calming-toner/for/mature-skin) — Superior fit — €16.87 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/es/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — €39.80 at Amazon
- Moisturizer: [Shiseido Benefiance Wrinkle Smoothing Cream](https://lovi.care/skincare/es/p/shiseido/benefiance-wrinkle-smoothing-cream-enriched/for/mature-skin) — Superior fit — €57.95 at Amazon
- SPF: [Bioré UV Perfect Milk SPF 50+ PA++++](https://lovi.care/skincare/es/p/biore/uv-face-milk-spf50-pa/for/mature-skin) — Superior fit — €25.88 at Amazon

## Where to buy

- Amazon.de: €22.99 (https://www.amazon.de/dp/B0BHVBVRYY?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- Notino: €23.70 (https://www.notino.es/mediheal/madecassoside-blemish-pad-almohadillas-tonificantes-contra-las-imperfecciones-de-la-piel/p-16306221/)
Prices checked 23 Oct – 6 Nov 2026.

## Ingredients

Water, Dipropylene Glycol, Glycereth-26, Niacinamide, Glycerin, 1,2-Hexanediol, Diphenyl Dimethicone, Triethylhexanoin, Hydroxyacetophenone, Hydrogenated Lecithin, Polyglyceryl-10 Oleate, Centella Asiatica Extract, Dipotassium Glycyrrhizate, Sodium Citrate, Allantoin, Octyldodeceth-16, Citric Acid, Disodium Edta, Polyglyceryl-10 Laurate, Juniperus Virginiana Oil, Butylene Glycol, Artemisia Vulgaris Oil, Pogostemon Cablin Oil, Madecassoside, Rosmarinus Officinalis Oil Leaf Rosemary Oil Leaf, Viola Odorata Leaf Extract, Centella Asiatica Root Extract, Centella Asiatica Leaf Extract, Saccharomyces Ferment, Mangifera Indica Fruit Extract, Lactobacillus Ferment, Asiaticoside, Madecassic Acid, Asiatic Acid
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/mediheal/madecassoside-blemish-pad/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/mediheal/madecassoside-blemish-pad/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/mediheal/madecassoside-blemish-pad/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/mediheal/madecassoside-blemish-pad/for/mature-skin
- France: https://lovi.care/skincare/fr/p/mediheal/madecassoside-blemish-pad/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/mediheal/madecassoside-blemish-pad/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/mediheal/madecassoside-blemish-pad/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/mediheal/madecassoside-blemish-pad/for/mature-skin (this page)
- Canada: https://lovi.care/skincare/ca/p/mediheal/madecassoside-blemish-pad/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/mediheal/madecassoside-blemish-pad/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/mediheal/madecassoside-blemish-pad/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/mediheal/madecassoside-blemish-pad/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/mediheal/madecassoside-blemish-pad/for/mature-skin