# Mediheal A:PE Protain Mask for dry skin

**Lovi Fit: High fit for dry skin.**
Dry Skin Fit: Superior · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/es/p/mediheal/a-pe-protain-mask/for/dry-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Brand: [Mediheal](https://lovi.care/skincare/es/brands/mediheal)
Category: [Face masks](https://lovi.care/skincare/es/best/face-masks)

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for dry skin; a few nourishing masks fit it even better.

## Why this fit

- Excellent suitability for your dry skin is provided by squalane and hydrolyzed collagen, which deeply hydrate and support your skin barrier function, addressing your dry or flaky skin concerns.
- The inclusion of milk protein and acetyl hexapeptide-8 further enhances skin repair and rejuvenation, offering significant nourishing mask benefits.
- The product is safe for your dry skin, as it contains soothing ingredients like niacinamide and glycerin and lacks harsh or irritating components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/es/p/mediheal/a-pe-protain-mask/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/es/p/mediheal/a-pe-protain-mask/for/dry-skin): High (this page)
- [Combination skin](https://lovi.care/skincare/es/p/mediheal/a-pe-protain-mask/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/es/p/mediheal/a-pe-protain-mask/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/es/p/mediheal/a-pe-protain-mask/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/es/p/mediheal/a-pe-protain-mask/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/es/p/mediheal/a-pe-protain-mask/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/es/p/mediheal/a-pe-protain-mask/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/es/p/mediheal/a-pe-protain-mask/for/oily-acne-prone-skin): High

## Key ingredients

Niacinamide, Hydrolyzed Collagen, Sodium Hyaluronate, Centella Asiatica Extract, Squalane

## What the research says

- Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group. ([American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/))
- Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days. ([Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/))
- Acetyl hexapeptide-3 and tripeptide-10 citrulline demonstrated antiwrinkle efficacy and decreased transepidermal water loss in twenty-four healthy volunteers compared to control groups, though synergistic effects between the two peptides remained unclear. ([Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28150423/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35818134/))
- Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks. ([International Journal of Molecular Sciences, 2022](https://pubmed.ncbi.nlm.nih.gov/35163025/))
- Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers. ([Marine Drugs, 2023](https://pubmed.ncbi.nlm.nih.gov/36827098/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))

## What reviewers say

Users with dry, sensitive, or compromised skin barriers report excellent outcomes, praising the mask for its rich, creamy essence that deeply moisturizes and calms redness. While highly effective for soothing irritation and flattening pimples, the heavy, milky texture can be too rich or sticky for those with oily or acne-prone skin.

- Liked: Rich hydration (mostly mentioned)
- Liked: Soothing and calming (mostly mentioned)
- Liked: Soft adherent sheet (often mentioned)
- Disliked: Heavy sticky finish (often mentioned)
- Liked: Barrier repair (sometimes noted)
- Disliked: Slow absorption (sometimes noted)
- Disliked: Artificial fragrance (rarely noted)
- Disliked: Fit issues (rarely noted)

## How to apply

- Use your sheet mask PM or AM whenever your skin feels dry. Start 3 times a week and increase if your skin likes it.
- Place the sheet mask on your face after cleansing and toner, and before moisturizer.
- Unfold the sheet mask and smooth it gently over your face without rubbing. Relax for ten minutes and let the essence soak in.
- Put the sheet mask on clean and slightly damp skin for the best hydration boost. Pat the remaining liquid softly into your skin.
- Avoid getting the essence too close to your eyes. Do a quick patch test before your very first use.
- Video: https://storage.pora.ai/cf9cbc1593b43309df7ca9cfe4fbbdae.mp4

## Questions and answers

### What makes Mediheal A:PE Protain Mask a great fit for dry skin?

Mediheal A:PE Protain Mask is a great fit because squalane and hydrolyzed collagen deeply hydrate and support the skin barrier, helping to care for dry and flaky areas. Ingredients like milk protein and acetyl hexapeptide-8 further improve skin repair, while soothing components like niacinamide and glycerin keep the application safe and gentle.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/)

### Which ingredients make this mask a good fit for dry skin?

Squalane and hydrolyzed collagen make this mask a great fit by deeply hydrating and supporting your skin barrier to address dry or flaky skin. Milk protein, acetyl hexapeptide-8, niacinamide, and glycerin further help nourish, repair, and soothe your skin.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/)

### What does Niacinamide do for dry skin?

Niacinamide helps dry skin by strengthening the skin barrier, increasing hydration, and reducing water loss. It supports ceramide production and helps keep the surface smooth and calm. This ingredient tends to be very well tolerated and is unlikely to irritate dry skin.
Sources: [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/), [Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/42108609/)

### What does Hydrolyzed Collagen do for dry skin?

Hydrolyzed Collagen helps improve skin moisture and keeps dry skin hydrated. Regular use may also reduce wrinkles and make the skin feel more smooth and elastic.
Sources: [Cureus, 2023](https://pubmed.ncbi.nlm.nih.gov/38192916/), [International Journal of Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33742704/)

### Where does this mask go in a skincare routine for dry skin?

This nourishing mask fits into your weekly routine after cleansing and before your treatment and moisturizer. It is a great fit for your dry skin because squalane and hydrolyzed collagen deeply hydrate and support your skin barrier.

### Can I use this mask with retinol, and in what order?

You can use this mask in your weekly routine, applying it after cleansing and before your treatment and moisturizer on nights you are not using retinol. It is unlikely to irritate dry skin because it contains soothing ingredients and lacks harsh components.

### How often should I use this mask?

Use this nourishing mask once a week in your weekly routine. It is a great fit for your dry skin, providing deep hydration and helping to support your skin barrier.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this mask clog pores, cause breakouts or purging for dry skin?

This mask is a great fit for dry skin because it deeply hydrates and supports your skin barrier with squalane and hydrolyzed collagen, while soothing ingredients like niacinamide and glycerin help keep your skin calm. It is very unlikely to clog pores or cause breakouts for your skin type, though some reviewers mention a heavy sticky finish or slow absorption.

### Is this mask fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetearyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for dry skin

- [Numbuzin No.2 Water Collagen 65% Voluming Sheet Mask](https://lovi.care/skincare/es/p/numbuzin/no-2-water-collagen-65-voluming-sheet-mask/for/dry-skin) — Superior fit — €14.99 at Amazon
- [Medicube Collagen Night Wrapping Mask](https://lovi.care/skincare/es/p/medicube/collagen-night-wrapping-mask/for/dry-skin) — High fit — €12.15 at Amazon
- [Etude House 0.2mm Therapy Air Mask](https://lovi.care/skincare/es/p/etude-house/0-2mm-therapy-air-mask/for/dry-skin) — High fit — €4.59 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/es/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — €8.85 at Amazon
- Hydrating Toner: [Paula's Choice Resist Advanced Replenishing Toner](https://lovi.care/skincare/es/p/paula-s-choice/advanced-replenishing-toner/for/dry-skin) — Superior fit — €34.00 at Amazon
- Moisturizer: [d'Alba First Spray Serum](https://lovi.care/skincare/es/p/d-alba/first-spray-serum/for/dry-skin) — Superior fit — €16.99 at Amazon

## Where to buy

No store in Spain has a checked price for this product, so the page shows none.

## Ingredients

Water, Dipropylene Glycol, Niacinamide, Propylene Glycol, Cetearyl Alcohol, Squalane, Glycerin, Hydrogenated Lecithin, C12-16 Alcohols, Palmitic Acid, Dipotassium Glycyrrhizate, Lactobacillus Eriodictyon Californicum Extract Ferment, Lactobacillus Soybean Extract Ferment, Centella Asiatica Extract, Origanum Vulgare Leaf Extract, Cinnamomum Cassia Bark Extract, Vitex Agnus Castus Extract, Chamomilla Recutita Extract Matricaria Extract, Chamaecyparis Obtusa Leaf Extract, Peg-12 Dimethicone, Hydroxyethyl Urea, Willow Bark Extract, Scutellaria Baicalensis Root Extract, Betaine, Bifida Ferment Filtrate, Pentylene Glycol, Xylitylglucoside, Adenosine, Anhydroxylitol, Leontopodium Alpinum Callus Culture Extract, Xylitol, Dimethicone, Extract Milk Protein, Tocopheryl Acetate, Hydrolyzed Collagen, Sodium Hyaluronate, Glucose, Portulaca Oleracea Extract, Butylene Glycol, Glycine, Serine, Glutamic Acid, Aspartic Acid, Leucine, Alanine, Lysine, Arginine, Tyrosine, Phenylalanine, Valine, Threonine, Proline, Isoleucine, Histidine, Methionine, Cysteine, Acetyl Hexapeptide-8, Phenoxyethanol, Copper Tripeptide-1, Ethylhexylglycerin, Disodium Edta, Carbomer, 1,2-Hexanediol, Zanthoxylum Piperitum Fruit Extract, Usnea Barbata Extract
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/mediheal/a-pe-protain-mask/for/dry-skin
- United Kingdom: https://lovi.care/skincare/uk/p/mediheal/a-pe-protain-mask/for/dry-skin
- Ireland: https://lovi.care/skincare/ie/p/mediheal/a-pe-protain-mask/for/dry-skin
- Germany: https://lovi.care/skincare/de/p/mediheal/a-pe-protain-mask/for/dry-skin
- France: https://lovi.care/skincare/fr/p/mediheal/a-pe-protain-mask/for/dry-skin
- Italy: https://lovi.care/skincare/it/p/mediheal/a-pe-protain-mask/for/dry-skin
- Netherlands: https://lovi.care/skincare/nl/p/mediheal/a-pe-protain-mask/for/dry-skin
- Spain: https://lovi.care/skincare/es/p/mediheal/a-pe-protain-mask/for/dry-skin (this page)
- Canada: https://lovi.care/skincare/ca/p/mediheal/a-pe-protain-mask/for/dry-skin
- Australia: https://lovi.care/skincare/au/p/mediheal/a-pe-protain-mask/for/dry-skin
- Singapore: https://lovi.care/skincare/sg/p/mediheal/a-pe-protain-mask/for/dry-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/mediheal/a-pe-protain-mask/for/dry-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/mediheal/a-pe-protain-mask/for/dry-skin