# Medicube Deep Reviving Peptide Eye Cream for combination skin

**Lovi Fit: High fit for combination skin.**
Combination Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/es/p/medicube/deep-reviving-peptide-eye-cream/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Brand: [Medicube](https://lovi.care/skincare/es/brands/medicube)
Category: [Eye care and eye patches](https://lovi.care/skincare/es/best/eye-creams)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for combination skin; a few eye cares fit it even better.

## Why this fit

- Offers excellent plumping and firming for your combination skin due to peptides like Palmitoyl Tripeptide-5 and Acetyl Hexapeptide-8, which also provide moderate benefits for oily shine and skin texture through niacinamide.
- Hyaluronic acid and niacinamide further support your combination skin by providing hydration and aiding in seboregulation, enhancing the overall efficacy.
- The formula is safe for your combination skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/es/p/medicube/deep-reviving-peptide-eye-cream/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/es/p/medicube/deep-reviving-peptide-eye-cream/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/es/p/medicube/deep-reviving-peptide-eye-cream/for/combination-skin): High (this page)
- [Sensitive skin](https://lovi.care/skincare/es/p/medicube/deep-reviving-peptide-eye-cream/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/es/p/medicube/deep-reviving-peptide-eye-cream/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/es/p/medicube/deep-reviving-peptide-eye-cream/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/es/p/medicube/deep-reviving-peptide-eye-cream/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/es/p/medicube/deep-reviving-peptide-eye-cream/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/es/p/medicube/deep-reviving-peptide-eye-cream/for/oily-acne-prone-skin): Average

## Key ingredients

Palmitoyl Tripeptide-5, Acetyl Hexapeptide-8, Niacinamide, Hyaluronic Acid, Hydrolyzed Collagen

## What the research says

- Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days. ([Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/))
- Supramolecular collagen nanoparticles composed of lactoferrin, recombinant human collagen, and palmitoyl tripeptide-5 improved transdermal efficiency by 69.90% and demonstrated moisturizing, whitening, wrinkle reduction, and firming effects. ([Colloids and Surfaces. B, Biointerfaces, 2025](https://pubmed.ncbi.nlm.nih.gov/39383579/))
- Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group. ([American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/))
- Acetyl hexapeptide-3 and tripeptide-10 citrulline demonstrated antiwrinkle efficacy and decreased transepidermal water loss in twenty-four healthy volunteers compared to control groups, though synergistic effects between the two peptides remained unclear. ([Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28150423/))
- Daily topical acetyl hexapeptide-8 showed a trend toward a longer time until return to baseline Jankovic Blepharospasm Rating Scale scores compared to placebo (3.7 months vs. 3.0 months) in 24 patients with blepharospasm receiving botulinum toxin therapy. ([European Journal of Neurology, 2013](https://pubmed.ncbi.nlm.nih.gov/23146065/))
- Argireline applied twice daily for 4 weeks achieved a total anti-wrinkle efficiency of 48.9% and notably reduced wrinkle depth compared to placebo in Chinese subjects. ([Journal of Cosmetic and Laser Therapy, 2013](https://pubmed.ncbi.nlm.nih.gov/23607739/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35818134/))
- Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks. ([International Journal of Molecular Sciences, 2022](https://pubmed.ncbi.nlm.nih.gov/35163025/))
- Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers. ([Marine Drugs, 2023](https://pubmed.ncbi.nlm.nih.gov/36827098/))

## What reviewers say

Based on a very large amount of data, this eye cream is highly praised for its rich yet fast-absorbing texture that layers well under makeup. Users report significant improvements in hydration, fine lines, and under-eye plumpness, often considering it a high-performing and affordable alternative to luxury brands. Some users find the scent strong or masculine, and a few consider the price steep for the amount provided, though these are infrequent concerns.

- Liked: Deep hydration (mostly mentioned)
- Liked: Lightweight texture (often mentioned)
- Liked: Gentle formula (sometimes noted)
- Liked: Great value (sometimes noted)
- Liked: Reduces lines (sometimes noted)
- Disliked: Caused milia (rarely noted)
- Disliked: High price (rarely noted)
- Disliked: Minimal results (rarely noted)
- Disliked: Packaging issues (rarely noted)
- Disliked: Unpleasant scent (rarely noted)

## Questions and answers

### What makes Medicube Deep Reviving Peptide Eye Cream a great fit for combination skin?

Medicube Deep Reviving Peptide Eye Cream is a great fit because its peptides like Palmitoyl Tripeptide-5 and Acetyl Hexapeptide-8 help plump and firm your skin. Hyaluronic acid and niacinamide also keep your combination skin hydrated while helping manage oily shine. The formula is very safe and unlikely to cause irritation.
Sources: [Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/), [Colloids and Surfaces. B, Biointerfaces, 2025](https://pubmed.ncbi.nlm.nih.gov/39383579/)

### Which ingredients make this cream a good fit for combination skin?

This cream is a great fit for your combination skin because it features peptides like Palmitoyl Tripeptide-5 and Acetyl Hexapeptide-8 for firming, alongside niacinamide and hyaluronic acid to hydrate dry areas while helping balance oily shine. The formula is safe for your skin with no risk of irritation from harsh ingredients.
Sources: [Colloids and Surfaces. B, Biointerfaces, 2025](https://pubmed.ncbi.nlm.nih.gov/39383579/), [Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/)

### What does Palmitoyl Tripeptide-5 do for combination skin?

Palmitoyl Tripeptide-5 helps smooth fine lines and keeps combination skin feeling soft and firm by supporting collagen production. This ingredient may also improve moisture levels and overall skin texture with regular use.
Sources: [Colloids and Surfaces. B, Biointerfaces, 2025](https://pubmed.ncbi.nlm.nih.gov/39383579/)

### What does Argireline do for combination skin?

Argireline helps smooth out lines and keeps combination skin feeling soft when applied twice daily. This ingredient may reduce wrinkle depth and improve overall skin texture, though its absorption through the skin is quite low.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Journal of Cosmetic and Laser Therapy, 2013](https://pubmed.ncbi.nlm.nih.gov/23607739/)

### Where does this cream go in a skincare routine for combination skin?

This eye care cream goes into your routine after your moisturizer or treatment step to keep the delicate eye area hydrated and firm. It is safe for daily use on combination skin and helps smooth fine lines without causing irritation.
Sources: [Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/), [Colloids and Surfaces. B, Biointerfaces, 2025](https://pubmed.ncbi.nlm.nih.gov/39383579/)

### Can I use this cream with retinol, and in what order?

You can use this cream alongside retinol by applying your retinol product first and following with this eye cream to keep your skin hydrated and comfortable. This gentle layering approach helps you avoid irritation while supporting your skin barrier.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use this cream?

You can use this eye cream daily as part of your regular morning and evening routine. The formula is safe for combination skin and is unlikely to cause irritation.

### Can this cream clog pores, cause breakouts or purging for combination skin?

This eye cream is a great fit for combination skin and is unlikely to cause clogged pores, breakouts, or purging. Its safe formula lacks harsh ingredients, and reviewers rarely mention any issues with milia.
Sources: [Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/), [Colloids and Surfaces. B, Biointerfaces, 2025](https://pubmed.ncbi.nlm.nih.gov/39383579/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetearyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for combination skin

- [Purito Centella Unscented Eye Cream](https://lovi.care/skincare/es/p/purito/centella-unscented-eye-cream/for/combination-skin) — Superior fit — €13.85 at Amazon
- [SKIN1004 Probio-Cica Bakuchiol Eye Cream](https://lovi.care/skincare/es/p/skin1004/probio-cica-bakuchiol-eye-cream/for/combination-skin) — High fit — €23.55 at Amazon
- [COSRX Advanced Snail Peptide Eye Cream](https://lovi.care/skincare/es/p/cosrx/advanced-snail-peptide-eye-cream/for/combination-skin) — High fit — €17.40 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/es/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — €39.80 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/es/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — €36.00 at Amazon
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/es/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/combination-skin) — Superior fit — €97.52 at Amazon

## Where to buy

- Amazon.de: €22.57 (https://www.amazon.de/dp/B09BF6S44F?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- Notino: €24.90 (https://www.notino.es/medicube/deep-lifting-peptide-eye-cream-crema-intensa-para-contorno-de-ojos-antiarrugas-y-antiojeras/p-16359259/)
Prices checked 11 Oct – 6 Nov 2026.

## Ingredients

Water, Glycerin, Butylene Glycol, Caprylic Capric Triglyceride, Niacinamide, Cetearyl Alcohol, Dimethicone, Hydrogenated Poly C6-14 Olefin, 1,2-Hexanediol, Cetearyl Olivate, Sorbitan Olivate, Palmitoyl Tripeptide-5, Acetyl Hexapeptide-8, Palmitoyl Pentapeptide-4, Adenosine, Tocopheryl Acetate, Allantoin, Panthenol, Hyaluronic Acid, Hydrolyzed Collagen, Beta-Glucan, Glyceryl Stearate, Peg-100 Stearate, Carbomer, Triethanolamine, Disodium Edta
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medicube/deep-reviving-peptide-eye-cream/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/medicube/deep-reviving-peptide-eye-cream/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/medicube/deep-reviving-peptide-eye-cream/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/medicube/deep-reviving-peptide-eye-cream/for/combination-skin
- France: https://lovi.care/skincare/fr/p/medicube/deep-reviving-peptide-eye-cream/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/medicube/deep-reviving-peptide-eye-cream/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/medicube/deep-reviving-peptide-eye-cream/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/medicube/deep-reviving-peptide-eye-cream/for/combination-skin (this page)
- Canada: https://lovi.care/skincare/ca/p/medicube/deep-reviving-peptide-eye-cream/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/medicube/deep-reviving-peptide-eye-cream/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/medicube/deep-reviving-peptide-eye-cream/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/medicube/deep-reviving-peptide-eye-cream/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/medicube/deep-reviving-peptide-eye-cream/for/combination-skin