# Medicube Collagen Niacinamide Jelly Cream for combination skin

**Lovi Fit: Average fit for combination skin.**
Combination Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/es/p/medicube/collagen-niacinamide-jelly-cream/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Brand: [Medicube](https://lovi.care/skincare/es/brands/medicube)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/es/best/moisturizers)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for combination skin; other moisturizers fit it better.

## Why this fit

- This product offers moderate benefits for your combination skin, with niacinamide helping to regulate oil production and trehalose providing hydration, though it is not specifically targeted for oily shine.
- Ingredients like glycerin and squalane offer general skincare support suitable for combination skin, but do not provide intensive treatment for your primary concern.
- The formula is safe for your combination skin, containing no harsh or prohibited ingredients that would cause irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/es/p/medicube/collagen-niacinamide-jelly-cream/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/es/p/medicube/collagen-niacinamide-jelly-cream/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/es/p/medicube/collagen-niacinamide-jelly-cream/for/combination-skin): Average (this page)
- [Sensitive skin](https://lovi.care/skincare/es/p/medicube/collagen-niacinamide-jelly-cream/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/es/p/medicube/collagen-niacinamide-jelly-cream/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/es/p/medicube/collagen-niacinamide-jelly-cream/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/es/p/medicube/collagen-niacinamide-jelly-cream/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/es/p/medicube/collagen-niacinamide-jelly-cream/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/es/p/medicube/collagen-niacinamide-jelly-cream/for/oily-acne-prone-skin): Average

## Key ingredients

Collagen, Niacinamide, Hydrolyzed Collagen, Water-Soluble Collagen, Squalane

## What the research says

- Sodium trehalose sulfate decreased transepidermal water loss and increased stratum corneum water content in participants with low stratum corneum water content when applied for 4 weeks compared to placebo. ([Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38606717/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35818134/))
- Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks. ([International Journal of Molecular Sciences, 2022](https://pubmed.ncbi.nlm.nih.gov/35163025/))
- Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers. ([Marine Drugs, 2023](https://pubmed.ncbi.nlm.nih.gov/36827098/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))

## What reviewers say

Based on a very large amount of data, this moisturizer is highly regarded for providing an immediate radiant glow and significant hydration, attributed to its unique cooling jelly texture. Some users find the finish to be sticky or tacky, and a portion of reviews suggest it performs better as a night mask compared to a daytime product.

- Liked: Glass skin glow (mostly mentioned)
- Liked: Deep hydration (often mentioned)
- Disliked: Sticky/tacky finish (often mentioned)
- Liked: Cooling jelly texture (sometimes noted)
- Liked: Plumping/firming (sometimes noted)
- Disliked: Absorption issues (sometimes noted)
- Disliked: Breakouts/irritation (rarely noted)
- Disliked: Fragrance/scent (rarely noted)

## How to apply

- Use this moisturizer in your AM and PM routine every day to control shine. Always pair with SPF in the morning.
- Apply this moisturizer after your cleanser and toner, right before your morning SPF.
- Gently press a small amount of the moisturizer into your skin and avoid harsh rubbing. Let it ⏳absorb for a minute.
- Apply the moisturizer on slightly damp skin to help it lock in moisture better. This keeps your combination skin balanced.
- Avoid the eye area when applying the moisturizer. Do a patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Medicube Collagen Niacinamide Jelly Cream work for combination skin?

This cream works moderately well for combination skin because niacinamide helps balance oil and trehalose adds hydration, though it is not specifically targeted for oily shine. It needs ingredients that actively reduce shine while keeping skin balanced and hydrated without causing irritation.
Sources: [Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38606717/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this cream a good fit for combination skin?

Niacinamide helps regulate oil production while trehalose and glycerin provide hydration, making this cream a reasonable fit for combination skin. To work best for this skin type, a product of this type needs targeted brightening and moisturizing ingredients that reduce oily shine without any risk of irritation.
Sources: [Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38606717/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Collagen do for combination skin?

Collagen helps keep combination skin smooth and hydrated by improving moisture and supporting elasticity. It is unlikely to cause irritation and may help reduce the appearance of fine lines while keeping the skin barrier balanced.
Sources: [Dermatology Practical & Conceptual, 2022](https://pubmed.ncbi.nlm.nih.gov/35223163/), [Current Issues in Molecular Biology, 2024](https://pubmed.ncbi.nlm.nih.gov/38534748/)

### What does Niacinamide do for combination skin?

Niacinamide helps balance oily areas by reducing excess shine and pore size while keeping dry patches hydrated and smooth. It also works to calm redness and even out skin tone, making it very suitable for combination skin.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### Where does this cream go in a skincare routine for combination skin?

This cream goes as the moisturizer step in your morning and evening routines after your toner and treatments. To work best for your combination skin, this type of product needs targeted oil control and balancing hydration that addresses both oily and dry areas.

### Can I use this cream with retinol, and in what order?

You can use this cream alongside retinol by applying the cream after your retinol has fully absorbed, which helps keep your skin comfortable and smooth while it adjusts to the retinoid. Combination skin of this type needs a lightweight moisturizer with niacinamide and soothing hydrators to support the skin barrier without feeling heavy.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### How often should I use this cream?

You can use this moisturizing treatment twice daily as part of your routine. Daily application helps improve skin moisture and supports the skin barrier, while being safe for your skin type.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this cream clog pores, cause breakouts or purging for combination skin?

This cream is unlikely to cause breakouts or irritation on your combination skin because the formula contains no harsh or prohibited ingredients. However, combination skin with oily shine needs targeted oil-balancing ingredients and lightweight hydrators that absorb quickly without feeling sticky.

### Can I use this cream around the eyes or on my body?

You can safely use this moisturizing treatment around the eyes and on the body, as the formula is gentle and free of harsh ingredients. However, because combination skin requires targeted care for different areas, your skin would benefit more from products with specialized ingredients that manage oily shine and provide intensive treatment.

### Is this cream fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (parfum).

## Alternatives for combination skin

- [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/es/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/combination-skin) — Superior fit — €13.67 at Amazon
- [The Ordinary Natural Moisturizing Factors + HA](https://lovi.care/skincare/es/p/the-ordinary/natural-moisturizing-factors-ha/for/combination-skin) — High fit — €11.50 at Amazon
- [belif The True Cream Aqua Bomb](https://lovi.care/skincare/es/p/belif/the-true-cream-aqua-bomb/for/combination-skin) — High fit — €35.00 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/es/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — €39.80 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/es/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — €36.00 at Amazon
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/es/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/combination-skin) — Superior fit — €97.52 at Amazon

## Where to buy

- Lookfantastic: €21.74 (https://www.lookfantastic.es/p/medicube-collagen-jelly-cream-110ml/16858534/)
Prices checked 15 Oct 2026.

## Ingredients

Water, Propanediol, Dipropylene Glycol, Butylene Glycol, Methylpropanediol, Diethoxyethyl Succinate, Ethoxydiglycol, Ammonium Acryloyldimethyltaurate Beheneth-25 Methacrylate Crosspolymer, Niacinamide, Trehalose, 1,2-Hexanediol, Chlorella Vulgaris Extract, Collagen, Hydrolyzed Collagen, Cynanchum Atratum Extract, Althaea Rosea Flower Extract, Water-Soluble Collagen, Allium Sativum Bulb Extract, Avena Sativa Kernel Extract Oat Kernel Extract, Bertholletia Excelsa Seed Extract, Brassica Oleracea Italica Extract, Camellia Sinensis Seed Extract, Salmon Egg Extract, Solanum Lycopersicum Fruit Extract Tomato Fruit Extract, Spinach Leaf Extract, Blueberry Fruit Extract, Wine Extract, Polyglyceryl-10 Isostearate, Tromethamine, Glucose, Polyglyceryl-10 Oleate, Ethylhexylglycerin, Fructooligosaccharides, Fructose, Adenosine, Sodium Phytate, Cyanocobalamin, Tocopherol, Pullulan, Glycerin, Hydroxypropyltrimonium Hyaluronate, Squalane, Soluble Proteoglycan, Hydrolyzed Elastin, Sodium Dna, Carbomer, Xanthan Gum, Parfum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medicube/collagen-niacinamide-jelly-cream/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/medicube/collagen-niacinamide-jelly-cream/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/medicube/collagen-niacinamide-jelly-cream/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/medicube/collagen-niacinamide-jelly-cream/for/combination-skin
- France: https://lovi.care/skincare/fr/p/medicube/collagen-niacinamide-jelly-cream/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/medicube/collagen-niacinamide-jelly-cream/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/medicube/collagen-niacinamide-jelly-cream/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/medicube/collagen-niacinamide-jelly-cream/for/combination-skin (this page)
- Canada: https://lovi.care/skincare/ca/p/medicube/collagen-niacinamide-jelly-cream/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/medicube/collagen-niacinamide-jelly-cream/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/medicube/collagen-niacinamide-jelly-cream/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/medicube/collagen-niacinamide-jelly-cream/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/medicube/collagen-niacinamide-jelly-cream/for/combination-skin