# Mary Kay Timewise Night Solution for dry skin

**Lovi Fit: Low fit for dry skin.**
Dry Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/es/p/mary-kay/timewise-night-solution/for/dry-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Brand: [Mary Kay](https://lovi.care/skincare/es/brands/mary-kay)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/es/best/moisturizers)

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A weak match for dry skin; the moisturizers alongside fit it better.

## Why this fit

- Offers moderate suitability for your dry skin due to the presence of glycerin, which provides humectant action, but lacks sufficient emollient and occlusive ingredients for optimal hydration.
- While the product offers general skincare benefits like hydration and soothing with ingredients such as Anthemis Nobilis Flower Extract and Rosa Centifolia Flower Extract, these are mostly supportive and not directly addressing your dry or flaky skin concerns.
- The safety profile is excellent, with no risks of irritation for your dry skin due to the absence of prohibited or harsh ingredients and the presence of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/es/p/mary-kay/timewise-night-solution/for/oily-skin): Low
- [Dry skin](https://lovi.care/skincare/es/p/mary-kay/timewise-night-solution/for/dry-skin): Low (this page)
- [Combination skin](https://lovi.care/skincare/es/p/mary-kay/timewise-night-solution/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/es/p/mary-kay/timewise-night-solution/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/es/p/mary-kay/timewise-night-solution/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/es/p/mary-kay/timewise-night-solution/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/es/p/mary-kay/timewise-night-solution/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/es/p/mary-kay/timewise-night-solution/for/dry-sensitive-skin): Low
- [Oily acne-prone skin](https://lovi.care/skincare/es/p/mary-kay/timewise-night-solution/for/oily-acne-prone-skin): Average

## Key ingredients

Palmitoyl Tripeptide-1, Retinyl Palmitate, Tocopheryl Acetate, Glycerin, Crithmum Maritimum Extract

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Vitamin E in O/W and W/O emulsions significantly increased stratum corneum hydration and enhanced water-binding capacity, with an optimum concentration of 5%. ([Arzneimittel-Forschung, 1998](https://pubmed.ncbi.nlm.nih.gov/9706379/))
- A multi-modal methodology combining MALDI-MSI, in vivo RCM, echography, and histology revealed age-related decreases in extracellular matrix and epidermal-dermal junction proteins and undulation depth, while a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 improved subepidermal low-echogenic band thickness, density, and extracellular matrix structure compared to placebo. ([Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/))
- Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants. ([Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/))
- Palmitoyl tetrapeptide-7, acetyl hexapeptide-8, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-10 significantly increased type III collagen levels in human dermal fibroblasts following UV exposure, with their combination demonstrating a greater effect in vitro and enhancing type I, III, and IV collagen levels in ex vivo skin tissues compared to individual components. ([International Journal of Cosmetic Science, 2026](https://pubmed.ncbi.nlm.nih.gov/42683869/))
- Over-the-counter retinol products provided only weak evidence for a mild ameliorating effect on fine facial skin wrinkle lines in randomized, double-blind, vehicle-controlled trials, and major methodological flaws call the validity of positive results into question. ([The Journal of Clinical and Aesthetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/34980969/))
- A cosmetic niacinamide/peptide/retinyl propionate regimen significantly improved periorbital wrinkle appearance relative to a 0.02% tretinoin regimen at 8 weeks with comparable benefits at 24 weeks, while demonstrating significantly better tolerability in 196 women. ([The British Journal of Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/20374604/))
- A novel triple-active cosmetic formulation containing 4-hexylresorcinol, retinyl propionate, and niacinamide improved the visual appearance of photoageing similarly to 0.02% tretinoin and reversed a consensus gene signature associated with ageing in female adults while causing less skin irritation. ([International Journal of Cosmetic Science, 2024](https://pubmed.ncbi.nlm.nih.gov/38685700/))
- Topical application of an antioxidant serum containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented particulate matter-induced degradation of extracellular matrix components, inflammation, and oxidative stress in the skin of 15 female volunteers compared to untreated controls. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40642809/))
- Dermatological products containing d-alpha tocopheryl acetate showed non-comedogenic potential with less than a 50% increase in microcomedones in 12 healthy male subjects compared to octyl palmitate. ([Contemporary Clinical Trials Communications, 2021](https://pubmed.ncbi.nlm.nih.gov/34471722/))
- Topical application of an antioxidant mix containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented PM and UV-induced skin barrier perturbation, lipid peroxidation, inflammatory markers, MMP9 activation, and Type I collagen loss in 15 healthy females compared to untreated exposed skin. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590207/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Preconditioning with samphire cell biomass formulations significantly accelerated epidermal permeability barrier repair kinetics after controlled stripping in healthy subjects older than 50 years compared to placebo and untreated sites. ([Journal of Cosmetic Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22151937/))
- Extracellular vesicles derived from Crithmum maritimum callus and miR167 promote wound healing and skin regeneration in human fibroblasts by downregulating MMP1 and upregulating COL1A1 and VEGFA without cytotoxicity. ([Biomolecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40867601/))
- The full-component extract of Crithmum maritimum significantly promotes epidermal regeneration of UV-induced skin damage in a barrier-weakening 3D full-skin model compared to oil-based extract components. ([RSC Advances, 2025](https://pubmed.ncbi.nlm.nih.gov/39835209/))

## Why other moisturizers fit dry skin better

- Aged Punica granatum extract significantly reduced UV-induced erythema and melanin levels while improving skin hydration and lightness compared to placebo in 60 women. ([Food Science & Nutrition, 2025](https://pubmed.ncbi.nlm.nih.gov/40755496/))
- Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans. ([Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))

## How to apply

- Could be used as part of your AM or PM routine. Start using it 3 times a week and work your way up to daily use.
- Apply your moisturizer after your toner and before your sunscreen in the morning. At night, use it as the final step after your serum.
- Gently press a small amount of the moisturizer into your skin. Avoid rubbing to keep your dry skin happy.
- Apply the moisturizer on slightly damp skin to help lock in extra hydration. This is great for soothing dry and flaky areas .
- Avoid the sensitive eye area and do a patch test before your first use .
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### Why is Mary Kay Night Solution a weak match for dry skin?

Mary Kay Night Solution is a weak match for dry skin because it provides only moderate moisture with glycerin and lacks enough softening and sealing ingredients to lock in hydration. A product of this type needs rich moisturizing agents, nourishing extracts, and barrier-supporting ingredients like sodium hyaluronate and niacinamide to properly care for dry skin.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a poor fit for dry skin?

Mary Kay Timewise Night Solution is a weak match for dry skin because it lacks enough softening and sealing ingredients to lock in moisture, even though it contains glycerin. A moisturizing treatment for dry skin needs rich moisturizing agents, nourishing extracts, and barrier-supporting ingredients like sodium hyaluronate and niacinamide to keep the skin soft and deeply hydrated.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Palmitoyl Tripeptide-1 do for dry skin?

Palmitoyl tripeptide-1 helps improve firmness, smoothness, and overall skin architecture. When paired with the right routine, it may also help reduce the appearance of fine lines and wrinkles by supporting collagen levels.
Sources: [Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/), [International Journal of Cosmetic Science, 2026](https://pubmed.ncbi.nlm.nih.gov/42683869/)

### What does Retinyl Palmitate do for dry skin?

Retinyl palmitate helps improve dryness by moisturizing the skin and smoothing out rough texture across various body sites. It also helps soften fine lines and wrinkles while keeping the skin feeling smooth.
Sources: [Journal of Cosmetic Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23438139/)

### Where does this serum go in a skincare routine for dry skin?

This treatment goes in the evening routine after cleansing and before your moisturizer. Because your dry skin needs more richness, a product of this type needs heavier moisturizing and softening ingredients to lock in hydration.

### Can I use this serum with niacinamide, and in what order?

You can use this treatment with niacinamide by applying niacinamide first and following with this treatment once it absorbs. This product is a weak match for your dry skin because it lacks heavy smoothing and sealing ingredients, so dry skin needs rich creams and oils to lock in moisture.

### How often should I use this serum?

This product is a weak match for your dry skin, as it lacks enough rich, sealing ingredients to lock in moisture and fully relieve dryness. A product for this skin needs rich, nourishing hydrators, heavy smoothing creams, and oils to repair and protect the skin barrier.

### Can this serum clog pores, cause breakouts or purging for dry skin?

This product is unlikely to clog pores or cause breakouts for dry skin. Its safety profile is excellent, with no harsh ingredients that typically cause irritation or breakouts.

### Can I use this serum around the eyes or on my body?

This product is generally safe to apply around the eyes or on the body, but it is unlikely to provide enough moisture for very dry skin. A product of this type needs rich smoothing and sealing ingredients to properly soften and comfort dry skin.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for dry skin

- [Kiehl's Midnight Recovery Concentrate](https://lovi.care/skincare/es/p/kiehl-s/midnight-recovery-concentrate/for/dry-skin) — Average fit — €54.78 at Amazon

## Routine for dry skin

### AM

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/es/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — €8.85 at Amazon
- Hydrating Toner: [Paula's Choice Resist Advanced Replenishing Toner](https://lovi.care/skincare/es/p/paula-s-choice/advanced-replenishing-toner/for/dry-skin) — Superior fit — €34.00 at Amazon
- Moisturizer: [d'Alba First Spray Serum](https://lovi.care/skincare/es/p/d-alba/first-spray-serum/for/dry-skin) — Superior fit — €16.99 at Amazon
- SPF: [Purito Daily Soft Touch Sunscreen](https://lovi.care/skincare/es/p/purito/daily-soft-touch-sunscreen/for/dry-skin) — Superior fit — €12.98 at Amazon

### PM

- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/es/p/missha/ultra-hyalon-cleansing-cream/for/dry-skin) — Superior fit — €10.97 at Amazon
- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/es/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — €8.85 at Amazon
- Serum or Treatment: [SKIN1004 Madagascar Centella Poremizing Fresh Ampoule](https://lovi.care/skincare/es/p/skin1004/madagascar-centella-poremizing-fresh-ampoule/for/dry-skin) — Superior fit — €14.98 at Amazon
- Moisturizer: [d'Alba First Spray Serum](https://lovi.care/skincare/es/p/d-alba/first-spray-serum/for/dry-skin) — Superior fit — €16.99 at Amazon

### Weekly

- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/es/p/missha/ultra-hyalon-cleansing-cream/for/dry-skin) — Superior fit — €10.97 at Amazon
- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/es/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — €8.85 at Amazon
- Nourishing Mask: [Abib Rice Probiotics Overnight Mask](https://lovi.care/skincare/es/p/abib/rice-probiotics-overnight-mask/for/dry-skin) — Superior fit — €15.30 at Amazon
- Serum or Treatment: [SKIN1004 Madagascar Centella Poremizing Fresh Ampoule](https://lovi.care/skincare/es/p/skin1004/madagascar-centella-poremizing-fresh-ampoule/for/dry-skin) — Superior fit — €14.98 at Amazon
- Moisturizer: [d'Alba First Spray Serum](https://lovi.care/skincare/es/p/d-alba/first-spray-serum/for/dry-skin) — Superior fit — €16.99 at Amazon

## Where to buy

No store in Spain has a checked price for this product, so the page shows none.

## Ingredients

Water, Butylene Glycol, Glycerin, 1-Methylhydantoin-2-Imide, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Tocopheryl Acetate, Retinyl Palmitate, Ascorbyl Palmitate, Crithmum Maritimum Extract, Geranium Extract, Mentha Arvensis Leaf Extract, Anthemis Nobilis Flower Extract, Rosa Centifolia Flower Extract, Citrus Aurantium Dulcis Flower Extract, Jasmine Extract, Ferula Galbaniflua Extract Gum, Cananga Odorata Flower Extract, Ribes Nigrum Fruit Extract Black Current Fruit Extract, Propylene Glycol, Hydroxyethylcellulose, Mannitol, Acrylates Vinyl Isodecanoate Crosspolymer, Cellulose, Hydroxypropyl Methylcellulose, Triethyl Citrate, Acrylates Ammonium Methacrylate Copolymer, Polysorbate 20, Carbomer, Triethanolamine, Disodium Edta, Talc, Methylparaben, Dmdm Hydantoin, Mica, Titanium Dioxide, Ultramarines, Red 30
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/mary-kay/timewise-night-solution/for/dry-skin
- United Kingdom: https://lovi.care/skincare/uk/p/mary-kay/timewise-night-solution/for/dry-skin
- Ireland: https://lovi.care/skincare/ie/p/mary-kay/timewise-night-solution/for/dry-skin
- Germany: https://lovi.care/skincare/de/p/mary-kay/timewise-night-solution/for/dry-skin
- France: https://lovi.care/skincare/fr/p/mary-kay/timewise-night-solution/for/dry-skin
- Italy: https://lovi.care/skincare/it/p/mary-kay/timewise-night-solution/for/dry-skin
- Netherlands: https://lovi.care/skincare/nl/p/mary-kay/timewise-night-solution/for/dry-skin
- Spain: https://lovi.care/skincare/es/p/mary-kay/timewise-night-solution/for/dry-skin (this page)
- Canada: https://lovi.care/skincare/ca/p/mary-kay/timewise-night-solution/for/dry-skin
- Australia: https://lovi.care/skincare/au/p/mary-kay/timewise-night-solution/for/dry-skin
- Singapore: https://lovi.care/skincare/sg/p/mary-kay/timewise-night-solution/for/dry-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/mary-kay/timewise-night-solution/for/dry-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/mary-kay/timewise-night-solution/for/dry-skin