Lancôme Rénergie H.P.N. 300-Peptide Cream for oily skin
Peptides
Sodium Hyaluronate
Niacinamide
Hydrolyzed Lupine Protein
Adenosine
Average
- AverageOily Skin Fit
- HighEffectiveness
- ConcerningSafety
Works for oily skin; other moisturizers fit it better.
This fit is calculated for the concerns frequently associated with oily skin: shine, enlarged pores, blackheads, and blemishes. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate suitability for your oily skin due to niacinamide's seboregulating properties, but it lacks sufficient ingredients for optimal oil control to address your oily shine.
- The presence of hydrolyzed hyaluronic acid and adenosine provides excellent moisturizing and anti-aging effects, which are generally beneficial but not directly targeted at your primary concern.
How to apply
- Could be used as part of your AM or PM routine every day to keep your face fresh.
- Apply this moisturizer after cleansing and toning, but right before your SPF in the morning.
- Gently press a small amount into your skin and let it absorb fully.
- Apply on clean, slightly dry skin to help control that oily shine.
- Avoid the eye area and do a quick patch test before your first use.
People Say
★4.7Overall rating based on 7.1k+ reviewsBased on a very large amount of data, this rich cream is highly recommended for mature and dry skin, effectively plumping, firming, and smoothing without greasiness, leading to a radiant complexion. Some users noted sensitivity to the fragrance and found the price to be high.
Highlights
Luxurious non-greasy texture Mostly Mentioned
- “rich cream that absorbs instantly”
- “feels like butter but not oily”
- “sinks in beautifully”
- “perfect under makeup”
Deep hydration Often Mentioned
- “skin feels hydrated all day”
- “no more dry patches”
- “leaves face feeling soft”
- “plumps up dehydration lines”
Visible anti-aging results Often Mentioned
- “jawline looks tighter”
- “fine lines are less visible”
- “skin feels plumper”
- “texture is much smoother”
High price point Often Mentioned
- “very expensive for the amount”
- “hard to justify the cost”
- “price is a bit steep”
- “wish it was more affordable”
Pleasant fragrance Sometimes Noted
- “smells absolutely divine”
- “light and fresh scent”
- “fragrance is lovely but not overpowering”
- “luxurious spa smell”
Refillable packaging Sometimes Noted
- “love that it is refillable”
- “beautiful heavy glass jar”
- “great sustainable option”
- “easy to replace the pod”
Heavy for oily skin Rarely Noted
- “too heavy for my oily zone”
- “made me look greasy”
- “clogged my pores”
- “better for night use only”
Lack of dramatic results Rarely Noted
- “didn't see a difference”
- “just a basic moisturizer”
- “not enough for very dry skin”
- “expected more for the price”
Skin irritation Rarely Noted
- “caused a red rash”
- “skin felt burning”
- “broke me out in hives”
- “irritated my sensitive skin”
Strong fragrance Rarely Noted
- “fragrance is too heavy”
- “smell lingers too long”
- “perfume irritated my eyes”
- “wish it was fragrance-free”
Sources: lovi.care, macys.com, ulta.com, lancome-usa.com, walmart.com, sephora.com, and more
Questions and answers
How well does Lancôme Rénergie H.P.N. 300-Peptide Cream work for oily skin?
This cream works moderately well for your oily skin, because it provides good moisture and helps balance oil, though it lacks enough targeted oil control ingredients. Oily skin needs a product that is highly suitable with strong oil-managing ingredients, lightweight hydration, and no heavy oils to keep pores clear and control shine.
International Journal of Molecular Sciences, 2026International Journal of Cosmetic Science, 2018
Which ingredients make this cream a good fit for oily skin?
This cream works moderately for oily skin thanks to niacinamide, which helps balance oil production. To fit oily skin even better, a product needs lightweight textures, ingredients that control oily shine, and gentle hydrators without heavy oils.
What do Peptides do for oily skin?
Peptides help support skin health and may improve the look of oily skin, but this type of skin needs formulas with ingredients that balance oil production and keep pores clear.
Advanced Science, 2025International Journal of Molecular Sciences, 2025
What does Hyaluronic Acid do for oily skin?
Hyaluronic acid helps oily skin by reducing extra oil and sebum production without causing irritation. Clinical studies show it successfully balances oil levels while keeping the skin comfortable.
Where does this cream go in a skincare routine for oily skin?
This moisturizing treatment goes near the end of your morning and evening routines after cleansers and toners, and before sunscreen in the morning. Oily skin works best with products that provide targeted oil-control ingredients and mattifying agents to properly manage excess shine.
Can I use this cream with retinol, and in what order?
You can use this cream with retinol by applying your retinol treatment first and following with this moisturizer. Using a moisturizer alongside retinol helps reduce unwanted dryness and irritation, while supporting your skin barrier. To properly manage oily shine, an oily skin type needs lightweight products with targeted oil-controlling ingredients.
How often should I use this cream?
You can use this moisturizing treatment twice daily as part of your routine. Daily application of a moisturizing cream helps improve skin hydration, fine lines, and texture without causing adverse events.
Journal of Cosmetic Dermatology, 2020Health Science Reports, 2021
Can this cream clog pores, cause breakouts or purging for oily skin?
This cream is unlikely to clog pores or cause breakouts for oily skin, though other products fit oily skin better because they offer stronger oil control.
Can I use this cream around the eyes or on my body?
You can use this moisturizing treatment around the eyes and on your body, but you should keep in mind that the skin on the eyelids is very thin and the skin on your back is thick. While this cream helps keep skin soft and smooth, an average fit for oily skin needs lighter balancing ingredients to control shine.
Is this cream fragrance-free and alcohol-free?
It contains fragrance (benzyl alcohol, geraniol, limonene, and parfum) and drying alcohol (alcohol denat).
What the research says
Adenosine-loaded dissolving microneedle patches showed similar or better efficacy on skin wrinkles, dermal density, elasticity, and hydration compared to adenosine cream in 22 female subjects.
International Journal of Cosmetic Science, 2018Horse oil-spread and adenosine-loaded dissolving microneedle patches significantly improved skin elasticity, hydration, dermal density, and wrinkles compared with adenosine-loaded dissolving microneedle patches in 20 women without causing adverse events.
Journal of Cosmetic Dermatology, 2019Topical application of a disodium adenosine monophosphate-based formulation reduced wrinkles and hyperpigmentation while improving hydration, barrier function, skin lifting, and epidermal turnover in female participants.
International Journal of Molecular Sciences, 2026Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.
Journal of Cosmetic Dermatology, 2021Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.
The Journal of Investigative Dermatology, 2008Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.
Dermatologic Surgery, 2005Topical adenosine treatment significantly increased the anagen hair growth rate and thick hair rate compared to placebo in Japanese women with female pattern hair loss over 12 months.
The Journal of Dermatology, 2008Adenosine and cordycepin stimulate the Wnt/beta-catenin signaling pathway through adenosine receptor and PKA activation, promoting cell proliferation, migration, and growth factor secretion in cultured dermal fibroblasts.
International Journal of Molecular Sciences, 2021Adenosine treatment of dermal papilla cells upregulates fibroblast growth factor-7 expression via the A2b adenosine receptor and intracellular cAMP signaling, and fibroblast growth factor-7 significantly stimulates hair fiber elongation in human scalp hair follicle organ cultures.
The Journal of Investigative Dermatology, 2007
Why other moisturizers fit oily skin better
A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions.
Journal of Cosmetic Dermatology, 2024
Ingredients
Water, Glycerin, Dimethicone, Cetearyl Alcohol, Theobroma Grandiflorum Seed Butter, Alcohol Denat, Cetearyl Isononanoate, Niacinamide, Glyceryl Stearate, Peg-100 Stearate, Isopropyl Palmitate, Octyldodecanol, Cyclodextrin, Hydrolyzed Lupine Protein, Pisum Sativum Extract, Adenosine, Capryloyl Salicylic Acid, Hydrolyzed Hyaluronic Acid, Hydrolyzed Linseed Extract, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Trisodium Ethylenediamine Disuccinate, Tocopheryl Acetate, Alba Cera, Beeswax, Cire Dabeille, Orbignya Oleifera Seed Oil, Jojoba Butter, Cetearyl Glucoside, Citric Acid, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Polysorbate 60, Potassium Cetyl Phosphate, Sorbitan Isostearate, Tocopherol, Dimethicone Polyglycerin-3 Crosspolymer, Benzyl Alcohol, Geraniol, Limonene, Chlorphenesin, Dipropylene Glycol, Phenoxyethanol, Sodium Benzoate, Parfum
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
Scan your face, then any product: Lovi shows how well it fits you and what fits even better.