# La Roche-Posay Anthelios AOX Daily Antioxidant Serum with Sunscreen SPF 50 for combination skin

**Lovi Fit: Superior fit for combination skin.**
Combination Skin Fit: High · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/es/p/la-roche-posay/anthelios-aox-daily-antioxidant-serum-with-sunscreen-spf-50/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Brand: [La Roche-Posay](https://lovi.care/skincare/es/brands/la-roche-posay)
Category: [Sunscreens and SPF moisturizers](https://lovi.care/skincare/es/best/sunscreens)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best sunscreens for combination skin.

## Why this fit

- Offers excellent protection against UV rays and antioxidant benefits for your combination skin, as avobenzone, homosalate, octisalate, octocrylene, and oxybenzone provide robust sun defense while tocopherol and ascorbyl glucoside combat oiliness and free radical damage.
- The inclusion of Scutellaria Baicalensis Root Extract and Cassia Alata Leaf Extract further enhances the formula's ability to soothe and protect, making it highly compatible with your skin's needs.
- This product is safe for your skin, with no risks of irritation due to the absence of harsh ingredients and the presence of beneficial soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/es/p/la-roche-posay/anthelios-aox-daily-antioxidant-serum-with-sunscreen-spf-50/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/es/p/la-roche-posay/anthelios-aox-daily-antioxidant-serum-with-sunscreen-spf-50/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/es/p/la-roche-posay/anthelios-aox-daily-antioxidant-serum-with-sunscreen-spf-50/for/combination-skin): Superior (this page)
- [Sensitive skin](https://lovi.care/skincare/es/p/la-roche-posay/anthelios-aox-daily-antioxidant-serum-with-sunscreen-spf-50/for/sensitive-skin): Superior
- [Acne-prone skin](https://lovi.care/skincare/es/p/la-roche-posay/anthelios-aox-daily-antioxidant-serum-with-sunscreen-spf-50/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/es/p/la-roche-posay/anthelios-aox-daily-antioxidant-serum-with-sunscreen-spf-50/for/dark-spots): Superior
- [Mature skin](https://lovi.care/skincare/es/p/la-roche-posay/anthelios-aox-daily-antioxidant-serum-with-sunscreen-spf-50/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/es/p/la-roche-posay/anthelios-aox-daily-antioxidant-serum-with-sunscreen-spf-50/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/es/p/la-roche-posay/anthelios-aox-daily-antioxidant-serum-with-sunscreen-spf-50/for/oily-acne-prone-skin): High

## Key ingredients

Baicalin, Ascorbic Acid, Vitamin E, Cell-Ox Shield Technology, Ascorbyl Glucoside

## What the research says

- Topical application of tocopherol succinate ethosomal gel decreased erythema, melanin, and sebum levels while improving moisture content and skin elasticity in 34 human women. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38268219/))
- Solid lipid nanoparticles bearing 5% oxybenzone incorporated into a cream base showed slower drug release, enhanced sun protection factor above 25, and prolonged retention in the stratum corneum compared to a plain cream base containing 5% oxybenzone. ([Journal of Microencapsulation, 2010](https://pubmed.ncbi.nlm.nih.gov/19622017/))
- Chemical sunscreens containing avobenzone, octocrylene, homosalate, and octisalate showed no to minimal risks of dermal irritation, sensitization, photo-allergy, and photo-irritation in human subjects. ([Journal of Drugs in Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40911743/))
- A nighttime topical antioxidant containing resveratrol, baicalin, and vitamin E significantly improved fine lines, wrinkles, firmness, elasticity, laxity, hyperpigmentation, radiance, roughness, and dermal thickness in subjects with mild to moderately photodamaged skin over 12 weeks. ([Journal of Drugs in Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/25607790/))
- Motor baicalin encapsulated in bio-vesicles enhanced water solubility, stability, transdermal penetration, antioxidant activity, and clinical skin antiaging efficacy compared to liposome baicalin and baicalin raw material. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/39946269/))
- Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants. ([Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- Topical application of an antioxidant serum containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented particulate matter-induced degradation of extracellular matrix components, inflammation, and oxidative stress in the skin of 15 female volunteers compared to untreated controls. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40642809/))
- Dermatological products containing d-alpha tocopheryl acetate showed non-comedogenic potential with less than a 50% increase in microcomedones in 12 healthy male subjects compared to octyl palmitate. ([Contemporary Clinical Trials Communications, 2021](https://pubmed.ncbi.nlm.nih.gov/34471722/))
- Topical application of an antioxidant mix containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented PM and UV-induced skin barrier perturbation, lipid peroxidation, inflammatory markers, MMP9 activation, and Type I collagen loss in 15 healthy females compared to untreated exposed skin. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590207/))
- Sunscreens containing Mexoryl SX provide superior protection against UVA- and solar-simulated radiation-induced biological damage, including pigmentation, DNA damage, immune suppression, and dermal alterations, compared to formulations without it in human volunteers and patients. ([Photodermatology, Photoimmunology & Photomedicine, 2008](https://pubmed.ncbi.nlm.nih.gov/18717957/))
- Mexoryl SX (5%) efficiently prevents UVA-induced skin alterations including pigmentation, stratum corneum thickening, and protein expression changes in human skin. ([Journal of Photochemistry and Photobiology. B, Biology, 1998](https://pubmed.ncbi.nlm.nih.gov/9745729/))
- Topical application of both a UVB absorber and a broad-spectrum Mexoryl SX sunscreen effectively prevented UVB-induced damage in in vitro reconstructed human skin, whereas only the Mexoryl SX-containing preparation successfully prevented UVA-specific dermal fibroblast disappearance. ([Photochemistry and Photobiology, 2000](https://pubmed.ncbi.nlm.nih.gov/10732449/))

## What reviewers say

Based on a very large amount of data, users with sensitive and aging skin highly praise this product for its dual function as a lightweight, non-greasy serum and a high-protection sunscreen that layers seamlessly under makeup. While many report visible improvements in skin texture and fine lines, a notable subset of users experiences irritation around the eyes and finds the price high for the small bottle size.

- Liked: Lightweight and non-greasy (mostly mentioned)
- Liked: Excellent makeup base (often mentioned)
- Liked: No white cast (often mentioned)
- Liked: Improves skin texture (sometimes noted)
- Liked: Suitable for sensitive skin (sometimes noted)
- Disliked: Eye irritation (sometimes noted)
- Disliked: High price (sometimes noted)
- Disliked: Packaging issues (rarely noted)
- Disliked: Scent complaints (rarely noted)
- Disliked: Staining potential (rarely noted)

## How to apply

- Apply this sunscreen during your AM routine every single day. Make sure to reapply ⏱ every two hours if you stay outside.
- Apply this sunscreen as the very last step of your morning routine after your moisturizer. Allow your moisturizer to ⏳ sink in for a minute first.
- Smooth an even layer over your face and gently pat it into the skin without harsh rubbing. Be sure to cover all exposed areas thoroughly.
- For the best finish on your combination skin, apply the sunscreen on completely dry skin over your moisturizer. This helps control any oily shine throughout the day.
- Avoid getting the product directly into your eyes. Do a small patch test before your first full application.
- Video: https://storage.pora.ai/53e9a436d82fca2a189dd08aa21de2fd.mp4

## Questions and answers

### What makes La Roche-Posay Anthelios AOX Serum one of the best fits for combination skin?

This serum is an excellent fit for combination skin because it combines strong sun defense with antioxidants like vitamin E and vitamin C derivatives that help combat oiliness and free radical damage. Plant extracts like Scutellaria Baicalensis Root Extract and Cassia Alata Leaf Extract further soothe and protect your skin without causing irritation.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38268219/)

### Which ingredients make this serum a good fit for combination skin?

Avobenzone, homosalate, octisalate, octocrylene, and oxybenzone make this serum a great fit by providing robust sun defense, while tocopherol and ascorbyl glucoside help combat oiliness and free radical damage. Additionally, ingredients like Scutellaria Baicalensis Root Extract and Cassia Alata Leaf Extract soothe and protect your combination skin.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38268219/)

### What does Baicalin do for combination skin?

Baicalin helps balance combination skin by fighting daily environmental damage and smoothing out rough spots, leaving your face feeling soft and calm. Because it works gently on various skin areas, it is unlikely to cause irritation while supporting a clear and even look.
Sources: [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/39946269/), [Journal of Drugs in Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/25607790/)

### What does Vitamin C do for combination skin?

Vitamin C helps brighten dull areas and smooth out uneven texture on combination skin while protecting against daily environmental stress. It may also help keep pores clear and skin firm by supporting collagen production, though drier spots may need an added moisturizer to stay comfortable.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/), [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37128827/)

### Where does this serum go in a skincare routine for combination skin?

This product goes in the morning routine as the final skincare step before makeup, right after your moisturizer. It provides strong sun defense and helps combat oiliness and free radical damage while being safe for your skin.
Sources: [Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/36607762/)

### Can I use this serum with retinol, and in what order?

You can use this sunscreen serum in your morning routine after your moisturizer, keeping retinol for your evening routine. This protects your combination skin from UV rays while avoiding any potential irritation from mixing strong active ingredients.

### How often should I use this serum?

You can use this serum every morning as the final step of your daytime routine to protect against UV rays and keep oiliness in check.
Sources: [Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/36607762/)

### Can this serum clog pores, cause breakouts or purging for combination skin?

This serum is unlikely to clog pores or cause breakouts on combination skin because its lightweight formula combats oiliness while avoiding heavy, pore-blocking ingredients. It is also formulated to be safe and gentle, with soothing components that help keep skin calm without triggering irritation.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38268219/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for combination skin

- [Bioderma Photoderm Mineral SPF 50+](https://lovi.care/skincare/es/p/bioderma/photoderm-mineral-fluide-spf50/for/combination-skin) — Superior fit — €19.13 at Amazon
- [Missha All Around Safe Block Soft Finish Sun Milk SPF 50+](https://lovi.care/skincare/es/p/missha/all-around-safe-block-soft-finish-sun-milk/for/combination-skin) — High fit — €20.99 at Amazon
- [SKIN1004 Centella Air-Fit Suncream Light](https://lovi.care/skincare/es/p/skin1004/centella-air-fit-suncream-light/for/combination-skin) — High fit — €13.99 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/es/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — €39.80 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/es/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — €36.00 at Amazon
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/es/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/combination-skin) — Superior fit — €97.52 at Amazon

## Where to buy

- Amazon.de: €18.65 (https://www.amazon.de/dp/B0GHP7WPN7?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
Prices checked 5 Nov 2026.

## Ingredients

Avobenzone, Homosalate, Octisalate, Octocrylene, Oxybenzone, Water, Dimethicone, Cyclopentasiloxane, Tocopherol, Acrylates Dimethicone Copolymer, Phenoxyethanol, Propylene Glycol, Caprylyl Glycol, Silica, Sodium Polyacrylate, Ascorbyl Glucoside, Scutellaria Baicalensis Root Extract, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Disodium Edta, Diethylhexyl Syringylidenemalonate, Polyacrylamide, C13-14 Isoparaffin, Laureth-7, Cassia Alata Leaf Extract, Maltodextrin, Triethanolamine
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/la-roche-posay/anthelios-aox-daily-antioxidant-serum-with-sunscreen-spf-50/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/la-roche-posay/anthelios-aox-daily-antioxidant-serum-with-sunscreen-spf-50/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/la-roche-posay/anthelios-aox-daily-antioxidant-serum-with-sunscreen-spf-50/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/la-roche-posay/anthelios-aox-daily-antioxidant-serum-with-sunscreen-spf-50/for/combination-skin
- France: https://lovi.care/skincare/fr/p/la-roche-posay/anthelios-aox-daily-antioxidant-serum-with-sunscreen-spf-50/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/la-roche-posay/anthelios-aox-daily-antioxidant-serum-with-sunscreen-spf-50/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/la-roche-posay/anthelios-aox-daily-antioxidant-serum-with-sunscreen-spf-50/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/la-roche-posay/anthelios-aox-daily-antioxidant-serum-with-sunscreen-spf-50/for/combination-skin (this page)
- Canada: https://lovi.care/skincare/ca/p/la-roche-posay/anthelios-aox-daily-antioxidant-serum-with-sunscreen-spf-50/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/la-roche-posay/anthelios-aox-daily-antioxidant-serum-with-sunscreen-spf-50/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/la-roche-posay/anthelios-aox-daily-antioxidant-serum-with-sunscreen-spf-50/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/la-roche-posay/anthelios-aox-daily-antioxidant-serum-with-sunscreen-spf-50/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/la-roche-posay/anthelios-aox-daily-antioxidant-serum-with-sunscreen-spf-50/for/combination-skin