# IT Cosmetics Bye Bye Dark Spots Serum for acne-prone skin

**Lovi Fit: High fit for acne-prone skin.**
Combination Skin Fit: High · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/es/p/it-cosmetics/bye-bye-dark-spots-serum/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Brand: [IT Cosmetics](https://lovi.care/skincare/es/brands/it-cosmetics)
Category: [Serums and treatments](https://lovi.care/skincare/es/best/serums)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for acne-prone skin; a few serums fit it even better.

## Why this fit

- Highly suitable for your combination skin, this serum effectively targets acne, blemishes, and breakouts with salicylic acid and 3-O-ethyl ascorbic acid, which provide moderate exfoliation and antioxidant support to address dark spots and even skin tone.
- Niacinamide and glycerin work synergistically to help regulate sebum production and offer soothing benefits, enhancing the overall efficacy for your skin concerns.
- The safety profile is excellent, with no risks of irritation due to the absence of harsh ingredients and the inclusion of beneficial components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/es/p/it-cosmetics/bye-bye-dark-spots-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/es/p/it-cosmetics/bye-bye-dark-spots-serum/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/es/p/it-cosmetics/bye-bye-dark-spots-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/es/p/it-cosmetics/bye-bye-dark-spots-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/es/p/it-cosmetics/bye-bye-dark-spots-serum/for/acne-prone-skin): High (this page)
- [Skin with dark spots](https://lovi.care/skincare/es/p/it-cosmetics/bye-bye-dark-spots-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/es/p/it-cosmetics/bye-bye-dark-spots-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/es/p/it-cosmetics/bye-bye-dark-spots-serum/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/es/p/it-cosmetics/bye-bye-dark-spots-serum/for/oily-acne-prone-skin): High

## Key ingredients

Niacinamide, 3-O-Ethyl Ascorbic Acid, Salicylic Acid, Glycerin, Caffeine

## What the research says

- Twice daily application of a multitargeted dermocosmetic cream provided comparable efficacy to benzoyl peroxide 5% gel in reducing inflammatory, non-inflammatory, and total lesions in 150 Caucasian subjects with mild-to-moderate acne over 56 days, while demonstrating superior skin tolerability. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/))
- The use of a salicylic acid-based dermocosmetic significantly reduces the needed quantity of benzoyl peroxide without impacting efficacy in mild to moderate acne, and as maintenance post-benzoyl peroxide allows a significant reduction of acne relapse compared to vehicle. ([Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/38051857/))
- A moisturizer containing licochalcone A, 1,2-decanediol, L-carnitine, and salicylic acid significantly reduced noninflammatory, inflammatory, and total acne lesion counts compared to a vehicle control in Thai patients during a 12-week maintenance phase. ([BioMed Research International, 2020](https://pubmed.ncbi.nlm.nih.gov/33150170/))
- Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical 2% niacinamide significantly decreased sebum excretion rate in Japanese individuals and casual sebum levels in Caucasian individuals compared to placebo or baseline. ([Journal of Cosmetic and Laser Therapy, 2006](https://pubmed.ncbi.nlm.nih.gov/16766489/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- Cryotherapy with liquid nitrogen achieved a higher cure rate (39%) than salicylic acid (24%) and a wait-and-see approach (16%) for cutaneous warts at 13 weeks in primary care patients. ([CMAJ, 2010](https://pubmed.ncbi.nlm.nih.gov/20837684/))
- Treatment with 2% supramolecular salicylic acid hydrogel resulted in a regression and markedly improvement rate of 51.01% compared to 43.10% for Adapaline gel in patients with mild to moderate facial acne vulgaris, showing no significant difference in efficacy. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590107/))
- Topical 5% benzoyl peroxide plus salicylic acid achieved the greatest lesion reduction at early 2 to 4 week time points compared to benzoyl peroxide, clindamycin, and combination benzoyl peroxide/clindamycin, while 5% benzoyl peroxide plus salicylic acid and combination benzoyl peroxide/clindamycin showed similar efficacy at 10 to 12 weeks in acne patients. ([Journal of the American Academy of Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/20488582/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- A topical cosmetic slimming product containing tetrahydroxypropyl ethylenediamine, caffeine, carnitine, forskolin and retinol significantly reduced body circumferences and improved skin aspect compared with placebo in 78 women over 12 weeks. ([International Journal of Cosmetic Science, 2011](https://pubmed.ncbi.nlm.nih.gov/21564138/))
- Topical sunscreen formulations containing caffeine combined with UV filters increased in vivo anti-UVB protection by approximately 25% and showed higher SPF values compared to caffeine-free sunscreen, while being well tolerated by the skin of healthy subjects. ([Frontiers in Physiology, 2019](https://pubmed.ncbi.nlm.nih.gov/31130869/))
- Caffeine gel combined with choline geranate showed high skin permeation capacity and superior clinical results in cellulite treatment compared to caffeine gel without ionic liquid. ([AAPS PharmSciTech, 2021](https://pubmed.ncbi.nlm.nih.gov/33796955/))

## How to apply

- Use your serum as part of your PM routine and start 3x/week before working up to daily use.
- Apply this treatment after cleansing and toner, and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the product on clean, dry skin to help manage your breakouts safely.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes IT Cosmetics Bye Bye Dark Spots Serum a great fit for acne-prone skin?

IT Cosmetics Bye Bye Dark Spots Serum is a great fit for acne-prone skin because it contains salicylic acid to target breakouts and dark spots while providing gentle exfoliation. Niacinamide and glycerin help calm the skin and keep oil balanced, and the formula has an excellent safety profile with very low risk of irritation.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/), [Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/38051857/)

### Which ingredients make this serum a good fit for acne-prone skin?

This serum is a great fit because it contains salicylic acid and 3-O-ethyl ascorbic acid, which help clear breakouts and fade dark spots. Niacinamide and glycerin also work together to calm your skin and keep oil balanced.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/), [Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/38051857/)

### What does Niacinamide do for acne-prone skin?

Niacinamide helps acne-prone skin by reducing both inflamed and uninflamed breakouts and calming redness. It is also very helpful for keeping oily skin balanced by cutting down on excess oil production, and it is well tolerated by most people.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38299457/), [Cureus, 2024](https://pubmed.ncbi.nlm.nih.gov/38725769/)

### What does 3-O-Ethyl Ascorbic Acid do for acne-prone skin?

3-O-Ethyl Ascorbic Acid helps acne-prone skin by reducing dark spots and fighting inflammation. This ingredient is generally well-suited for skin prone to breakouts, as it targets pigmentation while supporting overall skin health.
Sources: [Polymers, 2023](https://pubmed.ncbi.nlm.nih.gov/37571190/), [Free Radical Biology & Medicine, 2025](https://pubmed.ncbi.nlm.nih.gov/39778604/)

### Where does this serum go in a skincare routine for acne-prone skin?

This treatment serum goes in the evening routine after cleansing and before moisturizing, which keeps things simple and safe around sun exposure. It helps clear breakouts and dark spots while keeping skin calm, and is unlikely to cause irritation.
Sources: [International Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/31461548/), [Clinical, Cosmetic and Investigational Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/36798538/)

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first and following it with your retinol product, or by alternating the nights you use each one. Because this combination may cause dryness or irritation, using them on alternate nights or introducing them slowly helps your skin adjust comfortably.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/), [American Family Physician, 2012](https://pubmed.ncbi.nlm.nih.gov/23062156/)

### How often should I use this serum?

This treatment is best used in your evening routine, starting at once a week and slowly increasing frequency only if your skin tolerates it well. Salicylic acid and vitamin C help clear breakouts and dark spots while niacinamide and glycerin soothe the skin.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/), [Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/38051857/)

### Can this serum clog pores, cause breakouts or purging for acne-prone skin?

This serum is a great fit for acne-prone skin because it uses salicylic acid and vitamin C to help clear breakouts and dark spots without harsh ingredients that cause irritation. Niacinamide and glycerin also work together to keep oil in check and keep your skin calm and smooth.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/), [Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/38051857/)

### Is this serum fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (limonene, geraniol, and citronellol).

## Alternatives for acne-prone skin

- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/es/p/skinceuticals/c-e-ferulic/for/acne-prone-skin) — Superior fit — €169.99 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/es/p/neogen-dermalogy/real-vitamin-c-serum/for/acne-prone-skin) — Superior fit — €29.76 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/es/p/skin1004/probio-cica-intensive-ampoule/for/acne-prone-skin) — High fit — €21.99 at Amazon

## Pairs well with

- Cleanser: [B.LAB Matcha Hydrating Foam Cleanser](https://lovi.care/skincare/es/p/b-lab/matcha-hydrating-foam-cleanser/for/acne-prone-skin) — Superior fit — €11.99 at Amazon
- Hydrating Toner: [Paula's Choice Resist Advanced Replenishing Toner](https://lovi.care/skincare/es/p/paula-s-choice/advanced-replenishing-toner/for/acne-prone-skin) — Superior fit — €34.00 at Amazon
- Moisturizer: [SKIN1004 Centella Cream](https://lovi.care/skincare/es/p/skin1004/centella-cream/for/acne-prone-skin) — Superior fit — €17.49 at Amazon

## Where to buy

No store in Spain has a checked price for this product, so the page shows none.

## Ingredients

Water, Propylene Glycol, Glycerin, Niacinamide, Peg Ppg Polybutylene Glycol-8 5 3 Glycerin, Hydroxypropyl Tetrahydropyrantriol, Caffeine, 3-O-Ethyl Ascorbic Acid, Citric Acid, Phenoxyethanol, Ppg-6-Decyltetradeceth-30, Salicylic Acid, Xanthan Gum, Sodium Citrate, Hydroxyethylcellulose, Potassium Hydroxide, Disodium Edta, Limonene, Geraniol, Citronellol, Tocopherol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/it-cosmetics/bye-bye-dark-spots-serum/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/it-cosmetics/bye-bye-dark-spots-serum/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/it-cosmetics/bye-bye-dark-spots-serum/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/it-cosmetics/bye-bye-dark-spots-serum/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/it-cosmetics/bye-bye-dark-spots-serum/for/acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/it-cosmetics/bye-bye-dark-spots-serum/for/acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/it-cosmetics/bye-bye-dark-spots-serum/for/acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/it-cosmetics/bye-bye-dark-spots-serum/for/acne-prone-skin (this page)
- Canada: https://lovi.care/skincare/ca/p/it-cosmetics/bye-bye-dark-spots-serum/for/acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/it-cosmetics/bye-bye-dark-spots-serum/for/acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/it-cosmetics/bye-bye-dark-spots-serum/for/acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/it-cosmetics/bye-bye-dark-spots-serum/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/it-cosmetics/bye-bye-dark-spots-serum/for/acne-prone-skin