HydroPeptide Power Serum for mature skin

How to apply

Questions and answers

What the research says

• Hexapeptide-11 activated proteasome, autophagy, chaperones, and antioxidant response genes, protected fibroblasts against oxidative-stress-mediated premature cellular senescence, and improved skin elasticity in human subjects.

  Redox Biology, 2015

• Supramolecular collagen nanoparticles composed of lactoferrin, recombinant human collagen, and palmitoyl tripeptide-5 improved transdermal efficiency by 69.90% and demonstrated moisturizing, whitening, wrinkle reduction, and firming effects.

  Colloids and Surfaces. B, Biointerfaces, 2025

• Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone.

  Dermatologic Therapy, 2022

• A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers.

  Journal of Cosmetic Dermatology, 2020

• Hexapeptide-11 reversibly downregulated ATM and p53 protein expression in intrinsically aged fibroblasts, extrinsically aged fibroblasts, and extrinsically aged dermal papillae cells at concentrations between 0.1% and 1.0% in vitro, thereby influencing the onset of cellular senescence.

  Journal of Cosmetic Science, 2013

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

Ingredients

Water, Glycerin, Lactococcus Lysate Ferment, Butylene Glycol, Propanediol, Diethylhexyl Carbonate, Isopentyldiol, Pentylene Glycol, Diheptyl Succinate, Caprylyl Glycol, Hydroxyacetophenone, Olea Europaea Fruit Olive Fruit, Sodium Stearoyl Glutamate, Cetearyl Alcohol, Glyceryl Stearate, Potassium Olivoyl Hydrolyzed Oat Protein, Lysolecithin, Sclerotium Gum, Hexapeptide-11, Tetrahexyldecyl Ascorbate, 1,2-Hexanediol, Capryloyl Glycerin Sebacic Acid Copolymer, Phenylpropanol, Sorbitan Laurate, Pullulan, Xanthan Gum, Caprylic Capric Triglyceride, Glyceryl Oleate, Glycine Soja Seed Extract Soybean Seed Extract, Anogeissus Leiocarpus Bark Extract, Lemon Peel Extract, Palmitoyl Hexapeptide-19, Sodium Phytate, Hydroxyethylcellulose, Sodium Hyaluronate, Acetyl Dipeptide-1 Cetyl Ester, Citrus Aurantium Dulcis Peel Extract, Grapefruit Fruit Extract, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Bergamot Fruit Extract, Citrus Aurantifolia Peel Extract, Citrus Nobilis Fruit Extract Mandarin Orange Fruit Extract, Tangerine Peel Extract, Acetyl Hexapeptide-30, Barosma Betulina Leaf Extract, Vanilla Planifolia Fruit Extract, Vitis Vinifera Fruit Extract Grape Fruit Extract, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Palmitoyl Tripeptide-5, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Tocopherol

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.