# HydroPeptide Hydro-Lock Sleep Mask for acne-prone skin

**Lovi Fit: Average fit for acne-prone skin.**
Combination Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/es/p/hydropeptide/hydro-lock-sleep-mask/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Brand: [HydroPeptide](https://lovi.care/skincare/es/brands/hydropeptide)
Category: [Face masks](https://lovi.care/skincare/es/best/face-masks)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for acne-prone skin; other nourishing masks fit it better.

## Why this fit

- Offers moderate suitability for combination skin, as glycerin and panthenol provide essential hydration and barrier support without exacerbating oiliness or dryness.
- While beneficial for general skin health and hydration, the formula lacks targeted ingredients to effectively address your specific concerns of acne, blemishes, and breakouts.
- The product is safe for your combination skin, containing no harsh or prohibited ingredients that would cause irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/es/p/hydropeptide/hydro-lock-sleep-mask/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/es/p/hydropeptide/hydro-lock-sleep-mask/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/es/p/hydropeptide/hydro-lock-sleep-mask/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/es/p/hydropeptide/hydro-lock-sleep-mask/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/es/p/hydropeptide/hydro-lock-sleep-mask/for/acne-prone-skin): Average (this page)
- [Skin with dark spots](https://lovi.care/skincare/es/p/hydropeptide/hydro-lock-sleep-mask/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/es/p/hydropeptide/hydro-lock-sleep-mask/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/es/p/hydropeptide/hydro-lock-sleep-mask/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/es/p/hydropeptide/hydro-lock-sleep-mask/for/oily-acne-prone-skin): Average

## Key ingredients

Royal Peptide, Hydro-Lock Technology, Royal Jelly, Shea Butter, Pentapeptide-48

## What the research says

- A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- A prototype body cream containing bee venom, propolis, honey, beeswax, and royal jelly demonstrated stability for 90 days, high antioxidant capacity of 85.45%, lack of cytotoxicity with over 70% cell viability, and no irritation or allergic reaction in dermatological analysis, while improving skin parameters in a panel test. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35238152/))
- Applying an essence containing royal jelly extract significantly increased the stratum corneum water content of the cheeks compared to placebo in healthy Japanese adults over 4 weeks. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35778882/))
- Royal jelly protects against epidermal stress caused by UVB and menadione through the upregulation of NQO1 expression by its active compound 10-hydroxy-2-decenoic acid. ([International Journal of Molecular Sciences, 2021](https://pubmed.ncbi.nlm.nih.gov/34884772/))
- Defensin-1 from royal jelly stimulated MMP-9 secretion and increased keratinocyte migration and wound closure in vitro, and promoted re-epithelisation and wound closure in uninfected excision wounds. ([Scientific Reports, 2017](https://pubmed.ncbi.nlm.nih.gov/28779102/))
- A combination cream of stimu-tex AS and saccharide isomerate reduced erythema, increased skin capacitance, and reduced transepidermal water loss compared to placebo in 20 subjects after fractional CO2 laser procedure without causing serious adverse events. ([Lasers in Medical Science, 2025](https://pubmed.ncbi.nlm.nih.gov/41134387/))
- A skin barrier restoring cream with shea butter, silkflo, and vitamin E increased type I procollagen synthesis, enhanced antioxidant enzyme activity, decreased reactive oxygen species generation, and promoted hyaluronic acid production in H2O2-stimulated human keratinocyte cells compared to untreated cells. ([International Journal of Cosmetic Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39528438/))

## Why other nourishing masks fit acne-prone skin better

- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))

## How to apply

- You can use this creamy mask as part of your PM routine once a week. Start 3×/week if your skin tolerates it well.
- Apply the creamy mask after cleansing and toning, but always before your moisturizer .
- Smooth an even layer of the creamy mask over your face while avoiding any harsh rubbing. Let it sit ⏱ for the recommended time before rinsing.
- Apply the creamy mask on clean and dry skin for the best results against blemishes.
- Avoid the sensitive eye area and do a patch test before your very first use.
- Video: https://storage.pora.ai/1bd8a450c8dc72304ff10d2ee9cf85f9.mp4

## Questions and answers

### How well does HydroPeptide Hydro-Lock Sleep Mask work for acne-prone skin?

HydroPeptide Hydro-Lock Sleep Mask works moderately well for acne-prone skin, as glycerin and panthenol provide essential hydration and barrier support without making skin too oily or dry. However, the formula lacks targeted ingredients to effectively address breakouts. A nourishing mask for acne-prone skin needs soothing ingredients, niacinamide, retinol, or Centella asiatica to clear blemishes without irritation.
Sources: [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Which ingredients make this mask a good fit for acne-prone skin?

Glycerin and panthenol make this mask a moderate fit by providing essential hydration without making oily areas worse. However, because it lacks targeted ingredients for breakouts, a product for acne-prone skin needs effective soothing ingredients like niacinamide, retinol, or centella asiatica to address blemishes safely while keeping the skin balanced.
Sources: [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Royal Peptide do for acne-prone skin?

Royal Peptide helps calm angry, breakout-prone skin by soothing inflammation and supporting skin healing. It is unlikely to clog pores, but acne-prone skin needs lightweight, non-greasy hydration and gentle blemish-fighting ingredients to stay clear and smooth.
Sources: [BMC Complementary Medicine and Therapies, 2026](https://pubmed.ncbi.nlm.nih.gov/41803900/), [BMC Complementary Medicine and Therapies, 2020](https://pubmed.ncbi.nlm.nih.gov/33225942/)

### What does Hydro-Lock Technology do for acne-prone skin?

Hydro-Lock Technology helps keep acne-prone skin hydrated without clogging pores, which supports a healthy skin barrier and minimizes irritation. Using appropriate moisturizers helps reduce inflammation and improves overall treatment outcomes for acne-prone skin.
Sources: [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37605504/)

### Where does this mask go in a skincare routine for acne-prone skin?

This nourishing mask works as a nighttime moisturizer step in your routine to keep your skin soft and hydrated. While it is safe and provides good moisture, this skin type needs products with targeted blemish-fighting ingredients to properly manage breakouts.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this mask with retinol, and in what order?

You can use this nourishing mask with retinol by applying the mask after your retinol treatment to help lock in moisture and keep your skin soft. Using a soothing, barrier-supporting product alongside retinol is unlikely to cause irritation and may help ease the dryness that retinol sometimes brings.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [The Journal of Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/24930436/)

### How often should I use this mask?

You can use this nourishing mask regularly as part of your evening routine to keep your skin hydrated and soft. Since acne-prone skin needs targeted blemish-fighting ingredients alongside moisture, an acne-focused product may work better for your specific concerns.
Sources: [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/), [Journal of Drugs in Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/26151786/)

### Can this mask clog pores, cause breakouts or purging for acne-prone skin?

This mask is unlikely to cause irritation or purging on acne-prone skin, as it contains gentle ingredients that support the skin barrier. However, because it lacks targeted blemish-fighting ingredients, acne-prone skin needs a product that includes salicylic acid or tea tree oil to effectively clear pores and prevent breakouts.
Sources: [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Is this mask fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (limonene, citral, linalool, and geraniol).

## Alternatives for acne-prone skin

- [I'm From Mugwort Mask](https://lovi.care/skincare/es/p/i-m-from/mugwort-mask/for/acne-prone-skin) — Superior fit — €10.22 at Amazon
- [Clinique Moisture Surge Overnight Mask](https://lovi.care/skincare/es/p/clinique/moisture-surge-overnight-mask/for/acne-prone-skin) — High fit — €24.50 at Amazon
- [Laneige Water Sleeping Mask](https://lovi.care/skincare/es/p/laneige/water-sleeping-mask/for/acne-prone-skin) — High fit — €25.50 at Notino

## Pairs well with

- Cleanser: [B.LAB Matcha Hydrating Foam Cleanser](https://lovi.care/skincare/es/p/b-lab/matcha-hydrating-foam-cleanser/for/acne-prone-skin) — Superior fit — €11.99 at Amazon
- Hydrating Toner: [Paula's Choice Resist Advanced Replenishing Toner](https://lovi.care/skincare/es/p/paula-s-choice/advanced-replenishing-toner/for/acne-prone-skin) — Superior fit — €34.00 at Amazon
- Moisturizer: [SKIN1004 Centella Cream](https://lovi.care/skincare/es/p/skin1004/centella-cream/for/acne-prone-skin) — Superior fit — €17.49 at Amazon

## Where to buy

No store in Spain has a checked price for this product, so the page shows none.

## Ingredients

Water, Cyclopentasiloxane, Butylene Glycol, Propanediol, Glycerin, Panthenol, Peg-16 Macadamia Glycerides, Dimethiconol, Acrylates, Cyclohexasiloxane, Dimethicone, Dimethicone Crosspolymer, 2-Hexanediol, Caprylyl Glycol, Dipotassium Glycyrrhizate, Polysorbate 20, Butyrospermum Parkii Butter Shea Butter, Chlorphenesin, Sodium Hydroxide, Limonene, Hydrogenated Lecithin, Disodium Edta, Phenethyl Alcohol, Cyclotetrasiloxane, Ethylhexylglycerin, Citral, Maltodextrin, Linalool, Pentapeptide-48, Geraniol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/hydropeptide/hydro-lock-sleep-mask/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/hydropeptide/hydro-lock-sleep-mask/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/hydropeptide/hydro-lock-sleep-mask/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/hydropeptide/hydro-lock-sleep-mask/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/hydropeptide/hydro-lock-sleep-mask/for/acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/hydropeptide/hydro-lock-sleep-mask/for/acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/hydropeptide/hydro-lock-sleep-mask/for/acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/hydropeptide/hydro-lock-sleep-mask/for/acne-prone-skin (this page)
- Canada: https://lovi.care/skincare/ca/p/hydropeptide/hydro-lock-sleep-mask/for/acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/hydropeptide/hydro-lock-sleep-mask/for/acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/hydropeptide/hydro-lock-sleep-mask/for/acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/hydropeptide/hydro-lock-sleep-mask/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/hydropeptide/hydro-lock-sleep-mask/for/acne-prone-skin